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The map label for this gene is luxQ [H]

Identifier: 29349053

GI number: 29349053

Start: 4722402

End: 4724417

Strand: Reverse

Name: luxQ [H]

Synonym: BT_3645

Alternate gene names: 29349053

Gene position: 4724417-4722402 (Counterclockwise)

Preceding gene: 29349067

Following gene: 29349052

Centisome position: 75.47

GC content: 44.94

Gene sequence:

>2016_bases
ATGAGCCGATTGTCCCGAATTATCTTAGGATACCTTGTCTCTTTTTTGTTCATCGTTATTCCTGCAAAAGCCCAGAAAGA
AGCTGAAGTTTATAACGTTGATTCCTCTTTGTATGCCTACTATCAGCGTTGCCAGGAACATTTGCTGGAACCGGTCGTGC
TGAGTATGTCCGATACGCTGTTCCGTATGGCTAGCGGACAAAACGACCAGCGGATGCAGGCGGTAGCTCTCTCCACCCGG
CTGGACTATTATTATTACCAGGCCAATAATGAAGACAGCATCATTTTTTATACCAATAAGGTAAAACAATTCGCTAAAGA
AATACAGCAGTCCAAGTACTACTATTTCGCCTGGGCCAACCGGCTGATCCTATATTACCTGAAAACCGGAAGGAGTAACA
TCGCCCTCTATGAAGCCGAAAAAGTGCTGAAAGAGGCACAAGCCGAGGACAACAAGACCGGACTCATGTACTGCTACAAC
ATCATGTCGCAGATTTACACAATCAAGAACTTTGATGTCATGGCGTCCGAATGGCGCGTGAAAGAAATCGAACTGACCGA
AAAATACAAATTAGAAAACTATAATATCAGTAATACTTACGCTCAACTTGCCAATTACTACATTACGCATCATCAGCCGG
AACCAGCGCTGGAAGCACTGGAAAAAGCAGTAAAAACAGCCAACTCCGCCAGCCATAAAATACTGGCAAAGCTGACATAC
GTAGAGTATTACAGTGAATTTAAAGATTTCTCAGCAGCGGAGAAGATGCTGAAAGAATGCAGGGAACTGTTCGACCAGGA
CAAAAGGCTGGACTCACTCAAAAAAAGGTTTTACCGCACAGAGGCTTTCTACTACCAGCGCAGCAAACAGTTCGTCAAGG
CACTGGAAGCTGTCGAGAAGCAGAAAACCGAAGAGCAACGGCTGAATGAGTACGCCATGAGCAGCGGACAATACCGCCTC
AAAGGAGAAATCTACAGACAGATGGGCAGACCGGATGAAGCGGTGAAATTTCTGAAAAAGTATATTGAAGTAGACGATTC
TTTGAAAATAGCCAATGAACAACTGGCGAGCAGCGAATATGCCACGCTGCTAAATGTAGAAAAGCTCAATGCGGAGAAAA
AGGAATTAATGCTTCGGACAAAAGAAAAGGAGTTGAGCAATAAAACGACGCTGATTTTTTCATTGATCATCCTGTTAGCC
ATCCTCTTCTTGTTCTTATATCGGGAAAGCCGTCTGAACCGGAGGCTGAAGGCCTCGGAAAGTGAATTAAGAAATAAGAA
CGAAGAACTGACTTATTCGAGAGAAGAACTGCGCAAAGCCAGAGATCAGGCAGAAGCGACCAGCCAGATGAAAACGACTT
TTATTCAGAGTATGTCTCACGAAATACGGACACCGCTCAATTCGATCATAGGCTTCTCACAAGTATTAAGTGACCACTAC
GGCAATGAGGAAACGAAAGAATTCGTCAACATCATCAAAGCCAACACGGACGATCTGCTTCGACTCGTGACCGATGTGCT
CGCATTGTCGGAGCTCGACCAATATAACAAGCTCCCTACAAATATCCAAACGGATATCAATATGATCTGCCAGCTATCTA
TCGAAGTAGCTAAAATGCAGAAACAAGACACAGTCGAATTCCTTTTCAAACCGGAAAGGGAAAAACTAATCATACTCAGC
AATCCGGAACGCATTTCGCAGTTACTTGCCAATCTGGCACACAATGCGATCAAATTCACGACTCATGGCAGCATCGAACT
GACTTATTCGGTATTGGAAGCAGAAAAGAAACTCGAGATCAGCGTTACCGACACCGGTATAGGAATCCCTAAGGAGAAAC
AGGAAAAAGTATTCGAACGCTTCTACAAAATGAACTCCTTCTCACAGGGCACGGGCCTCGGACTGTCGATCAGCCGGACG
ATTGCCGAAAAGTTAGGAGGCAGCCTCCACATCGATTCATCCTATACGGACGGGTGCCGGATGGTGCTGACTCTTCCTTT
GGTATATGCTGAGTAA

Upstream 100 bases:

>100_bases
GCAAATGTAGATAAAAAAAGCAAGTATTCGTATTAAAATTAGGAAATAAACGTATATTTGCAATCAATAGCAATCAATAG
AACTACCGAAAACGAATACC

Downstream 100 bases:

>100_bases
AAAACGCTTCTGACCGATACCAAATCCGAAAGAATAGCCTATCTTTGCAACATTTAAAAATAAAAGCTCAGGCTATGAAA
CTTTCTGCTCTTTACCAGAT

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSRLSRIILGYLVSFLFIVIPAKAQKEAEVYNVDSSLYAYYQRCQEHLLEPVVLSMSDTLFRMASGQNDQRMQAVALSTR
LDYYYYQANNEDSIIFYTNKVKQFAKEIQQSKYYYFAWANRLILYYLKTGRSNIALYEAEKVLKEAQAEDNKTGLMYCYN
IMSQIYTIKNFDVMASEWRVKEIELTEKYKLENYNISNTYAQLANYYITHHQPEPALEALEKAVKTANSASHKILAKLTY
VEYYSEFKDFSAAEKMLKECRELFDQDKRLDSLKKRFYRTEAFYYQRSKQFVKALEAVEKQKTEEQRLNEYAMSSGQYRL
KGEIYRQMGRPDEAVKFLKKYIEVDDSLKIANEQLASSEYATLLNVEKLNAEKKELMLRTKEKELSNKTTLIFSLIILLA
ILFLFLYRESRLNRRLKASESELRNKNEELTYSREELRKARDQAEATSQMKTTFIQSMSHEIRTPLNSIIGFSQVLSDHY
GNEETKEFVNIIKANTDDLLRLVTDVLALSELDQYNKLPTNIQTDINMICQLSIEVAKMQKQDTVEFLFKPEREKLIILS
NPERISQLLANLAHNAIKFTTHGSIELTYSVLEAEKKLEISVTDTGIGIPKEKQEKVFERFYKMNSFSQGTGLGLSISRT
IAEKLGGSLHIDSSYTDGCRMVLTLPLVYAE

Sequences:

>Translated_671_residues
MSRLSRIILGYLVSFLFIVIPAKAQKEAEVYNVDSSLYAYYQRCQEHLLEPVVLSMSDTLFRMASGQNDQRMQAVALSTR
LDYYYYQANNEDSIIFYTNKVKQFAKEIQQSKYYYFAWANRLILYYLKTGRSNIALYEAEKVLKEAQAEDNKTGLMYCYN
IMSQIYTIKNFDVMASEWRVKEIELTEKYKLENYNISNTYAQLANYYITHHQPEPALEALEKAVKTANSASHKILAKLTY
VEYYSEFKDFSAAEKMLKECRELFDQDKRLDSLKKRFYRTEAFYYQRSKQFVKALEAVEKQKTEEQRLNEYAMSSGQYRL
KGEIYRQMGRPDEAVKFLKKYIEVDDSLKIANEQLASSEYATLLNVEKLNAEKKELMLRTKEKELSNKTTLIFSLIILLA
ILFLFLYRESRLNRRLKASESELRNKNEELTYSREELRKARDQAEATSQMKTTFIQSMSHEIRTPLNSIIGFSQVLSDHY
GNEETKEFVNIIKANTDDLLRLVTDVLALSELDQYNKLPTNIQTDINMICQLSIEVAKMQKQDTVEFLFKPEREKLIILS
NPERISQLLANLAHNAIKFTTHGSIELTYSVLEAEKKLEISVTDTGIGIPKEKQEKVFERFYKMNSFSQGTGLGLSISRT
IAEKLGGSLHIDSSYTDGCRMVLTLPLVYAE
>Mature_670_residues
SRLSRIILGYLVSFLFIVIPAKAQKEAEVYNVDSSLYAYYQRCQEHLLEPVVLSMSDTLFRMASGQNDQRMQAVALSTRL
DYYYYQANNEDSIIFYTNKVKQFAKEIQQSKYYYFAWANRLILYYLKTGRSNIALYEAEKVLKEAQAEDNKTGLMYCYNI
MSQIYTIKNFDVMASEWRVKEIELTEKYKLENYNISNTYAQLANYYITHHQPEPALEALEKAVKTANSASHKILAKLTYV
EYYSEFKDFSAAEKMLKECRELFDQDKRLDSLKKRFYRTEAFYYQRSKQFVKALEAVEKQKTEEQRLNEYAMSSGQYRLK
GEIYRQMGRPDEAVKFLKKYIEVDDSLKIANEQLASSEYATLLNVEKLNAEKKELMLRTKEKELSNKTTLIFSLIILLAI
LFLFLYRESRLNRRLKASESELRNKNEELTYSREELRKARDQAEATSQMKTTFIQSMSHEIRTPLNSIIGFSQVLSDHYG
NEETKEFVNIIKANTDDLLRLVTDVLALSELDQYNKLPTNIQTDINMICQLSIEVAKMQKQDTVEFLFKPEREKLIILSN
PERISQLLANLAHNAIKFTTHGSIELTYSVLEAEKKLEISVTDTGIGIPKEKQEKVFERFYKMNSFSQGTGLGLSISRTI
AEKLGGSLHIDSSYTDGCRMVLTLPLVYAE

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=273, Percent_Identity=30.7692307692308, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=28.515625, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=29.0322580645161, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=27.5862068965517, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788713, Length=257, Percent_Identity=26.8482490272374, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1790436, Length=295, Percent_Identity=26.4406779661017, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=29.6943231441048, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788393, Length=236, Percent_Identity=27.5423728813559, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=25.6410256410256, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=261, Percent_Identity=26.4367816091954, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=24.6861924686192, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=238, Percent_Identity=27.3109243697479, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=25.3061224489796, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=25.974025974026, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=331, Percent_Identity=23.8670694864048, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788279, Length=331, Percent_Identity=26.8882175226586, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=25.9414225941423, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78121; Mature: 77990

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50005 TPR L=RR ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLSRIILGYLVSFLFIVIPAKAQKEAEVYNVDSSLYAYYQRCQEHLLEPVVLSMSDTL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
FRMASGQNDQRMQAVALSTRLDYYYYQANNEDSIIFYTNKVKQFAKEIQQSKYYYFAWAN
HHHHCCCCCHHHHHHHHHHHHEEEEEEECCCCCEEEEEHHHHHHHHHHHHCCEEEEEHHH
RLILYYLKTGRSNIALYEAEKVLKEAQAEDNKTGLMYCYNIMSQIYTIKNFDVMASEWRV
HHHEEEEECCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCEE
KEIELTEKYKLENYNISNTYAQLANYYITHHQPEPALEALEKAVKTANSASHKILAKLTY
EEEEHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
VEYYSEFKDFSAAEKMLKECRELFDQDKRLDSLKKRFYRTEAFYYQRSKQFVKALEAVEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKTEEQRLNEYAMSSGQYRLKGEIYRQMGRPDEAVKFLKKYIEVDDSLKIANEQLASSEY
HHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCHHH
ATLLNVEKLNAEKKELMLRTKEKELSNKTTLIFSLIILLAILFLFLYRESRLNRRLKASE
HHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SELRNKNEELTYSREELRKARDQAEATSQMKTTFIQSMSHEIRTPLNSIIGFSQVLSDHY
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
GNEETKEFVNIIKANTDDLLRLVTDVLALSELDQYNKLPTNIQTDINMICQLSIEVAKMQ
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KQDTVEFLFKPEREKLIILSNPERISQLLANLAHNAIKFTTHGSIELTYSVLEAEKKLEI
HHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHEEEEECCCEEEHHHHHHHCCCEEE
SVTDTGIGIPKEKQEKVFERFYKMNSFSQGTGLGLSISRTIAEKLGGSLHIDSSYTDGCR
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCHH
MVLTLPLVYAE
HHHEECHHCCC
>Mature Secondary Structure 
SRLSRIILGYLVSFLFIVIPAKAQKEAEVYNVDSSLYAYYQRCQEHLLEPVVLSMSDTL
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
FRMASGQNDQRMQAVALSTRLDYYYYQANNEDSIIFYTNKVKQFAKEIQQSKYYYFAWAN
HHHHCCCCCHHHHHHHHHHHHEEEEEEECCCCCEEEEEHHHHHHHHHHHHCCEEEEEHHH
RLILYYLKTGRSNIALYEAEKVLKEAQAEDNKTGLMYCYNIMSQIYTIKNFDVMASEWRV
HHHEEEEECCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCEE
KEIELTEKYKLENYNISNTYAQLANYYITHHQPEPALEALEKAVKTANSASHKILAKLTY
EEEEHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
VEYYSEFKDFSAAEKMLKECRELFDQDKRLDSLKKRFYRTEAFYYQRSKQFVKALEAVEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKTEEQRLNEYAMSSGQYRLKGEIYRQMGRPDEAVKFLKKYIEVDDSLKIANEQLASSEY
HHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCHHH
ATLLNVEKLNAEKKELMLRTKEKELSNKTTLIFSLIILLAILFLFLYRESRLNRRLKASE
HHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SELRNKNEELTYSREELRKARDQAEATSQMKTTFIQSMSHEIRTPLNSIIGFSQVLSDHY
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
GNEETKEFVNIIKANTDDLLRLVTDVLALSELDQYNKLPTNIQTDINMICQLSIEVAKMQ
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KQDTVEFLFKPEREKLIILSNPERISQLLANLAHNAIKFTTHGSIELTYSVLEAEKKLEI
HHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHEEEEECCCEEEHHHHHHHCCCEEE
SVTDTGIGIPKEKQEKVFERFYKMNSFSQGTGLGLSISRTIAEKLGGSLHIDSSYTDGCR
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCHH
MVLTLPLVYAE
HHHEECHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]