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The map label for this gene is purN [H]

Identifier: 29348292

GI number: 29348292

Start: 3603002

End: 3603586

Strand: Reverse

Name: purN [H]

Synonym: BT_2883

Alternate gene names: 29348292

Gene position: 3603586-3603002 (Counterclockwise)

Preceding gene: 29348293

Following gene: 29348291

Centisome position: 57.56

GC content: 34.87

Gene sequence:

>585_bases
ATGAAATCTTTTAATATTGTAGTGTGTGCGTCTGGTGGTGGAGGAAATTTTCGTTCTTTGATAAAATATCAATGTGATTA
TGGTTATCACATTTCGTTACTGATAGTAGATAGAGAGTGTCCTGCTATTAAGATAGCAAAGGAAAATGGGATATCATATT
CCGTTTTAGAAAAGAAAGTTTTAGGCAAGTCTTTTTTTGAGGAGTTTGAGAAGATTGTCCCCATAGATACGAATTTAATT
GTTTTAGCAGGATTTCTACCGATTATACCCAAATGGATTTGTGAAAAGTGGGAACGTAAAATAATAAATATTCATCCTTC
ACTATTGCCAAAATATGGAGGGAAAGGCATGTATGGGGTTAAAGTGCAAGAAGCTATTTTGAGGAATCATGAGAAGTATG
CCGGCTGTACCGTTCATTATGTGGATTCGGAAATAGACACTGGCGAGATAATAGCTCAAAAAAAAATACTTGTGATGGAG
AATGAGTCTGCATGGGAATTGGGAGGCAGAGTTTTTAATGAAGAAATAATATTACTTCCGTTGGCTATTAAACATATACG
TGAAGCAATGAAAGTGATTCCTTAA

Upstream 100 bases:

>100_bases
GCCTTATTTGTCGATGATAGATGTATTAATGAATAATACCAAAGATGAAGTCAATGATTTATTGGATTCTTTTTGTGTAA
GATATTGAAATTGCTTAGAT

Downstream 100 bases:

>100_bases
GATTGAATATAAGTGTATTATATAATATTATACGATTTTCGATATGACACAATGCCCATTGGTTAGTATTTCTTGTCTGA
CCTATAATCATGCTCCGTAT

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKSFNIVVCASGGGGNFRSLIKYQCDYGYHISLLIVDRECPAIKIAKENGISYSVLEKKVLGKSFFEEFEKIVPIDTNLI
VLAGFLPIIPKWICEKWERKIINIHPSLLPKYGGKGMYGVKVQEAILRNHEKYAGCTVHYVDSEIDTGEIIAQKKILVME
NESAWELGGRVFNEEIILLPLAIKHIREAMKVIP

Sequences:

>Translated_194_residues
MKSFNIVVCASGGGGNFRSLIKYQCDYGYHISLLIVDRECPAIKIAKENGISYSVLEKKVLGKSFFEEFEKIVPIDTNLI
VLAGFLPIIPKWICEKWERKIINIHPSLLPKYGGKGMYGVKVQEAILRNHEKYAGCTVHYVDSEIDTGEIIAQKKILVME
NESAWELGGRVFNEEIILLPLAIKHIREAMKVIP
>Mature_194_residues
MKSFNIVVCASGGGGNFRSLIKYQCDYGYHISLLIVDRECPAIKIAKENGISYSVLEKKVLGKSFFEEFEKIVPIDTNLI
VLAGFLPIIPKWICEKWERKIINIHPSLLPKYGGKGMYGVKVQEAILRNHEKYAGCTVHYVDSEIDTGEIIAQKKILVME
NESAWELGGRVFNEEIILLPLAIKHIREAMKVIP

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=191, Percent_Identity=28.7958115183246, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI209869995, Length=191, Percent_Identity=28.7958115183246, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI209869993, Length=191, Percent_Identity=28.7958115183246, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1788846, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17567511, Length=188, Percent_Identity=28.7234042553192, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582400, Length=196, Percent_Identity=30.1020408163265, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 21923; Mature: 21923

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFNIVVCASGGGGNFRSLIKYQCDYGYHISLLIVDRECPAIKIAKENGISYSVLEKKV
CCCEEEEEEECCCCCCHHHHHEEECCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHH
LGKSFFEEFEKIVPIDTNLIVLAGFLPIIPKWICEKWERKIINIHPSLLPKYGGKGMYGV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCCCCCCEECH
KVQEAILRNHEKYAGCTVHYVDSEIDTGEIIAQKKILVMENESAWELGGRVFNEEIILLP
HHHHHHHHCCCCCCCCEEEEECCCCCCCHHEEEEEEEEEECCCHHHHCCEEECCCEEEEH
LAIKHIREAMKVIP
HHHHHHHHHHHHCC
>Mature Secondary Structure
MKSFNIVVCASGGGGNFRSLIKYQCDYGYHISLLIVDRECPAIKIAKENGISYSVLEKKV
CCCEEEEEEECCCCCCHHHHHEEECCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHH
LGKSFFEEFEKIVPIDTNLIVLAGFLPIIPKWICEKWERKIINIHPSLLPKYGGKGMYGV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCCCCCCEECH
KVQEAILRNHEKYAGCTVHYVDSEIDTGEIIAQKKILVMENESAWELGGRVFNEEIILLP
HHHHHHHHCCCCCCCCEEEEECCCCCCCHHEEEEEEEEEECCCHHHHCCEEECCCEEEEH
LAIKHIREAMKVIP
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA