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The map label for this gene is lolE [H]

Identifier: 29348247

GI number: 29348247

Start: 3540896

End: 3542122

Strand: Reverse

Name: lolE [H]

Synonym: BT_2838

Alternate gene names: 29348247

Gene position: 3542122-3540896 (Counterclockwise)

Preceding gene: 29348248

Following gene: 29348239

Centisome position: 56.58

GC content: 43.44

Gene sequence:

>1227_bases
GTGAATTTTCCCTTCTACATAGCTCGGCGTTATCTTTTCTCGAAAAAGAAGCATAATGCTATCAATATTATTTCCGGCAT
ATCAGTATGCGGGGTGGCACTTGCTACGTTGGCACTGGTCTGCACGCTTTCCGTATTCAACGGATTTCAGGATATGGTAG
CCAGCTTTTTCACAGCTTTTGATCCTCAGTTGAAGATTACCATCCGCGAGGGAAAAGTCTTCGACGGACAGGATGAAAGG
ATTCGTGCGGTCTGTGCGCTTCCGGAGGTCTCGGTATCTACAGAGACGCTGGAAGAGAATGCGATGGTGCAATATAAAGA
CCGTCAGGCTATGGTTGTGTTGAAAGGCGTGGAAGATAACTTTGAGGATTTAACCGAAATAGATAACATTCTTTACGGAG
CCGGCGAGTTTATTCTTCATGATTCGATAGTGAATTATGGGGTGATGGGCGTGGAACTGGTTTCGACTTTGGGTACCGGA
CTGGCGTTCGTAGATCCTTTGCAGGTGTATCTTCCCAAGCGTAATGCCAAAGTGAATATGGCGAATCCCGGGGCTTCTTT
CAATCGCGACTATCTTTATTCACCGGGTGTTGTGTTCGTGGTCAACCAACAGAAGTATGATGAAAGCTATATTCTCACTT
CCCTTGATTTCCTTCGTAACTTATTGGACTATACGACAGAGGTTTCTGGCATTGAGTTGAAACTGAAACCGAATACCAAT
ATATCATCCGTACAGTCTAAAATAGAAAAAATGCTGGGTGATGACTTTGTGGTACAGAACCGTTATCAGCAGCAAGCAGA
TGTTTTCCGTATCATGGAAATAGAGAAGCTGATCTCTTATCTGTTTCTTACTTTTATTCTGATGATTGCCTGTTTTAATG
TGATCGGTTCTCTTTCTATGTTGATTCTGGATAAGAAAGACGATGTCATAACCTTGCGCAGTTTGGGAGCCAGTGATAAA
CTGATATCCCGTATCTTTTTATTTGAGGGACGGCTCATCTCTCTCTTTGGTGCTATCTCCGGTATTATACTGGGGTTGAT
ATTATGTTTTATTCAGCAGAAGTTTGGCATCATTACCCTTGGCGGAGGTGGTGGAACTTTTGTGGTGGACGCTTATCCGG
TAAGTGTCCATGCATGGGATGTAGTGCTTATTTTTATTACTGTTTTAGCAGTGGGATTCCTGTCAGTATGGTATCCAGTG
CGTTACTTAAGCAAGCGGCTTCTGTAA

Upstream 100 bases:

>100_bases
TCGGAACCCGTGTGCGTCATCAATTACGGATTATTCCCGAATTGAAGTTCTTCGTGGACGACTCACTGGATTATATTGAG
AAGATTGATTCTTTGCTGAA

Downstream 100 bases:

>100_bases
TTGGCTGAAGAAGAAAAAGGCTATAACCTTTGAATACAGAAGTGTAGGTGCTTTGTAGAGGAGTTTGCTAAAATGGAACA
GAGTGTTTCATGTATTTATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MNFPFYIARRYLFSKKKHNAINIISGISVCGVALATLALVCTLSVFNGFQDMVASFFTAFDPQLKITIREGKVFDGQDER
IRAVCALPEVSVSTETLEENAMVQYKDRQAMVVLKGVEDNFEDLTEIDNILYGAGEFILHDSIVNYGVMGVELVSTLGTG
LAFVDPLQVYLPKRNAKVNMANPGASFNRDYLYSPGVVFVVNQQKYDESYILTSLDFLRNLLDYTTEVSGIELKLKPNTN
ISSVQSKIEKMLGDDFVVQNRYQQQADVFRIMEIEKLISYLFLTFILMIACFNVIGSLSMLILDKKDDVITLRSLGASDK
LISRIFLFEGRLISLFGAISGIILGLILCFIQQKFGIITLGGGGGTFVVDAYPVSVHAWDVVLIFITVLAVGFLSVWYPV
RYLSKRLL

Sequences:

>Translated_408_residues
MNFPFYIARRYLFSKKKHNAINIISGISVCGVALATLALVCTLSVFNGFQDMVASFFTAFDPQLKITIREGKVFDGQDER
IRAVCALPEVSVSTETLEENAMVQYKDRQAMVVLKGVEDNFEDLTEIDNILYGAGEFILHDSIVNYGVMGVELVSTLGTG
LAFVDPLQVYLPKRNAKVNMANPGASFNRDYLYSPGVVFVVNQQKYDESYILTSLDFLRNLLDYTTEVSGIELKLKPNTN
ISSVQSKIEKMLGDDFVVQNRYQQQADVFRIMEIEKLISYLFLTFILMIACFNVIGSLSMLILDKKDDVITLRSLGASDK
LISRIFLFEGRLISLFGAISGIILGLILCFIQQKFGIITLGGGGGTFVVDAYPVSVHAWDVVLIFITVLAVGFLSVWYPV
RYLSKRLL
>Mature_408_residues
MNFPFYIARRYLFSKKKHNAINIISGISVCGVALATLALVCTLSVFNGFQDMVASFFTAFDPQLKITIREGKVFDGQDER
IRAVCALPEVSVSTETLEENAMVQYKDRQAMVVLKGVEDNFEDLTEIDNILYGAGEFILHDSIVNYGVMGVELVSTLGTG
LAFVDPLQVYLPKRNAKVNMANPGASFNRDYLYSPGVVFVVNQQKYDESYILTSLDFLRNLLDYTTEVSGIELKLKPNTN
ISSVQSKIEKMLGDDFVVQNRYQQQADVFRIMEIEKLISYLFLTFILMIACFNVIGSLSMLILDKKDDVITLRSLGASDK
LISRIFLFEGRLISLFGAISGIILGLILCFIQQKFGIITLGGGGGTFVVDAYPVSVHAWDVVLIFITVLAVGFLSVWYPV
RYLSKRLL

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=419, Percent_Identity=24.1050119331742, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787360, Length=405, Percent_Identity=21.9753086419753, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45573; Mature: 45573

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPFYIARRYLFSKKKHNAINIISGISVCGVALATLALVCTLSVFNGFQDMVASFFTAF
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPQLKITIREGKVFDGQDERIRAVCALPEVSVSTETLEENAMVQYKDRQAMVVLKGVEDN
CCCEEEEEECCCEECCCCHHEEHEEECCCCCCCHHHHHCCCEEEECCCCEEEEEECCCCC
FEDLTEIDNILYGAGEFILHDSIVNYGVMGVELVSTLGTGLAFVDPLQVYLPKRNAKVNM
HHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHCHHHHEECCCCCEEEE
ANPGASFNRDYLYSPGVVFVVNQQKYDESYILTSLDFLRNLLDYTTEVSGIELKLKPNTN
CCCCCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
ISSVQSKIEKMLGDDFVVQNRYQQQADVFRIMEIEKLISYLFLTFILMIACFNVIGSLSM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LILDKKDDVITLRSLGASDKLISRIFLFEGRLISLFGAISGIILGLILCFIQQKFGIITL
EEEECCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
GGGGGTFVVDAYPVSVHAWDVVLIFITVLAVGFLSVWYPVRYLSKRLL
ECCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFPFYIARRYLFSKKKHNAINIISGISVCGVALATLALVCTLSVFNGFQDMVASFFTAF
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPQLKITIREGKVFDGQDERIRAVCALPEVSVSTETLEENAMVQYKDRQAMVVLKGVEDN
CCCEEEEEECCCEECCCCHHEEHEEECCCCCCCHHHHHCCCEEEECCCCEEEEEECCCCC
FEDLTEIDNILYGAGEFILHDSIVNYGVMGVELVSTLGTGLAFVDPLQVYLPKRNAKVNM
HHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHCHHHHEECCCCCEEEE
ANPGASFNRDYLYSPGVVFVVNQQKYDESYILTSLDFLRNLLDYTTEVSGIELKLKPNTN
CCCCCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
ISSVQSKIEKMLGDDFVVQNRYQQQADVFRIMEIEKLISYLFLTFILMIACFNVIGSLSM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LILDKKDDVITLRSLGASDKLISRIFLFEGRLISLFGAISGIILGLILCFIQQKFGIITL
EEEECCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
GGGGGTFVVDAYPVSVHAWDVVLIFITVLAVGFLSVWYPVRYLSKRLL
ECCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]