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The map label for this gene is prpC [H]

Identifier: 29348181

GI number: 29348181

Start: 3434041

End: 3435690

Strand: Reverse

Name: prpC [H]

Synonym: BT_2772

Alternate gene names: 29348181

Gene position: 3435690-3434041 (Counterclockwise)

Preceding gene: 29348182

Following gene: 29348180

Centisome position: 54.88

GC content: 37.76

Gene sequence:

>1650_bases
ATGAAAGAAGAAAATATATATAACTATTGTCACATTGCAGGGCGTACCGACATTGGCTGCAAACGTCAGGCAAATGAAGA
CAGTATGGGCAACTTCGAAACGATCAATGGCCTTGCTGCTGTTGTATGTGACGGTATGGGAGGGCACGTCGGAGGAGCTA
CGGCATCCCGCTTAGCTGTAGAAGCGATTCATGGTTTTCTTGACGGACAGTATTATGAAGATCCTCGTGAAGCCATTGGA
GAAGCTATTGATGCTGCCAATAAGGCTATACTTCATCAGGCAATGATACAACCTGAGTTGCAGGGAATGGGGTCTACATG
TGTATTGTTGTTGGTCCGTGACTCTAAAGTTTATATAGGTCATGTGGGAGATAGTCGTGTTTACCTAATACGTAACAGAT
GTATAAAACAACTAACCAAGGATCACTCTTATGTACAGATGTTGGTGGATATGGGACAACTGACTAATGAGCAGGCAGAA
CATCACCCACGGAAAAACGAAATAACAAATGCTTTAGGCATTGCCAATATGAAACCGGCTACAGTACTGCCTGATGCGAT
TTTACCCGAAGCTGGAGATTGTTTTTTGCTTTGTTCGGATGGATTGAGCGGAATGATATCAGATAGGGAGATAGAACGCA
TCGTCAGCAGACAATCTGAAATGGGGTCACAGGAACGTGTGGACTATTTAGTACAACGAGCAAGGGACAATGGGGGATTG
GACAATATAACGGTAGAGATTGTAGAGTTTTCTATTACTCCTGGTTCGCCTTCTAAACCTCAAAGAAGAAAAATAGGAAT
GATCATATTAACTGTCATTTTGCTGATATGTATTGGCGCCAGTGGAGGTTATTATTTTTGGAATAAGCATTTTAAGTCGG
AATCTATTACTATATATAAATCCTTTATGCGAAGGGATACAATTATTATGTTGCCTGAAATTAAGTTCCAGAAAGGTGAA
GATATTTTAGAAATAAATTATAAGCAAGGACATACGGAGATCCTTATGGGCAAAGAAAAAGAAAAGGTGATAGAAATAAA
CCGTGCTCTGTCAAGTGATTCATTAAAGTATGATGAGGATATTGATGTGGCATATGGTAACCGTCTTTTAGTGTTTCGAC
AAGAGTTTAAAAACGAACAATTGCGTTTTTCTTTGGCAGACTCTGTGAAGATATTCAAATTTGTTGTTCCTGTGGTAAAA
GATATGACATTGACACAGCCGAAGCAAACTCATCAAGAATCTACTCCCTCTGTTGTAAATGATGTAAGTAATACCGCAAA
TGGTAGTATTGTTGCTATTGTGGCAGCTACTGGAAAAGTGGATTCTCTTACATATAGAGTTGATGCTCAGTTTGTTCCTA
AAAGAAAAGCCTTTTCTTTTATTGAAGGTGAGAATGCGTGTTTTTTAGTTGAAGGACAATCACAGCCTTCAAAACTCAAT
CGTCATTTTCAGATAACTGACATAGAATATGATGCAACTTATTTCAAGAAAACAAAAAAGGAAACAGGATTTGATATCTC
TTTTACAGAGAAAGAACCACCTAAAAAAATAGATATTGTAATAAAAGGAAAAGAGAAAGAAGGAGAGAACTCTACTGATG
TATTACTTAATATAATTATTAGTCTTAATATTAATAAGGAAGGAAAATAG

Upstream 100 bases:

>100_bases
TGTAGGTGACCGTGTACAGTTGTATACGAATGATGTTATTGTTTTGGGAGCTACCAAAATGATTTTCTTGGCTATTCCTC
AATAAAAAGCAAATTAGGCA

Downstream 100 bases:

>100_bases
TTATGCCTGAATATGAATTGATAAAAGTAATAGGTCAAGGAGGCATGGGCAGCGTCTATGAAGGGAGAAGTGGCGATGGG
AAACGTGTAGCAATAAAGAT

Product: putative protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKEENIYNYCHIAGRTDIGCKRQANEDSMGNFETINGLAAVVCDGMGGHVGGATASRLAVEAIHGFLDGQYYEDPREAIG
EAIDAANKAILHQAMIQPELQGMGSTCVLLLVRDSKVYIGHVGDSRVYLIRNRCIKQLTKDHSYVQMLVDMGQLTNEQAE
HHPRKNEITNALGIANMKPATVLPDAILPEAGDCFLLCSDGLSGMISDREIERIVSRQSEMGSQERVDYLVQRARDNGGL
DNITVEIVEFSITPGSPSKPQRRKIGMIILTVILLICIGASGGYYFWNKHFKSESITIYKSFMRRDTIIMLPEIKFQKGE
DILEINYKQGHTEILMGKEKEKVIEINRALSSDSLKYDEDIDVAYGNRLLVFRQEFKNEQLRFSLADSVKIFKFVVPVVK
DMTLTQPKQTHQESTPSVVNDVSNTANGSIVAIVAATGKVDSLTYRVDAQFVPKRKAFSFIEGENACFLVEGQSQPSKLN
RHFQITDIEYDATYFKKTKKETGFDISFTEKEPPKKIDIVIKGKEKEGENSTDVLLNIIISLNINKEGK

Sequences:

>Translated_549_residues
MKEENIYNYCHIAGRTDIGCKRQANEDSMGNFETINGLAAVVCDGMGGHVGGATASRLAVEAIHGFLDGQYYEDPREAIG
EAIDAANKAILHQAMIQPELQGMGSTCVLLLVRDSKVYIGHVGDSRVYLIRNRCIKQLTKDHSYVQMLVDMGQLTNEQAE
HHPRKNEITNALGIANMKPATVLPDAILPEAGDCFLLCSDGLSGMISDREIERIVSRQSEMGSQERVDYLVQRARDNGGL
DNITVEIVEFSITPGSPSKPQRRKIGMIILTVILLICIGASGGYYFWNKHFKSESITIYKSFMRRDTIIMLPEIKFQKGE
DILEINYKQGHTEILMGKEKEKVIEINRALSSDSLKYDEDIDVAYGNRLLVFRQEFKNEQLRFSLADSVKIFKFVVPVVK
DMTLTQPKQTHQESTPSVVNDVSNTANGSIVAIVAATGKVDSLTYRVDAQFVPKRKAFSFIEGENACFLVEGQSQPSKLN
RHFQITDIEYDATYFKKTKKETGFDISFTEKEPPKKIDIVIKGKEKEGENSTDVLLNIIISLNINKEGK
>Mature_549_residues
MKEENIYNYCHIAGRTDIGCKRQANEDSMGNFETINGLAAVVCDGMGGHVGGATASRLAVEAIHGFLDGQYYEDPREAIG
EAIDAANKAILHQAMIQPELQGMGSTCVLLLVRDSKVYIGHVGDSRVYLIRNRCIKQLTKDHSYVQMLVDMGQLTNEQAE
HHPRKNEITNALGIANMKPATVLPDAILPEAGDCFLLCSDGLSGMISDREIERIVSRQSEMGSQERVDYLVQRARDNGGL
DNITVEIVEFSITPGSPSKPQRRKIGMIILTVILLICIGASGGYYFWNKHFKSESITIYKSFMRRDTIIMLPEIKFQKGE
DILEINYKQGHTEILMGKEKEKVIEINRALSSDSLKYDEDIDVAYGNRLLVFRQEFKNEQLRFSLADSVKIFKFVVPVVK
DMTLTQPKQTHQESTPSVVNDVSNTANGSIVAIVAATGKVDSLTYRVDAQFVPKRKAFSFIEGENACFLVEGQSQPSKLN
RHFQITDIEYDATYFKKTKKETGFDISFTEKEPPKKIDIVIKGKEKEGENSTDVLLNIIISLNINKEGK

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 61383; Mature: 61383

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEENIYNYCHIAGRTDIGCKRQANEDSMGNFETINGLAAVVCDGMGGHVGGATASRLAV
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCEEEEEECCCCCCCCCCHHHHHHH
EAIHGFLDGQYYEDPREAIGEAIDAANKAILHQAMIQPELQGMGSTCVLLLVRDSKVYIG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEEEEECCEEEEE
HVGDSRVYLIRNRCIKQLTKDHSYVQMLVDMGQLTNEQAEHHPRKNEITNALGIANMKPA
ECCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCCCCCCC
TVLPDAILPEAGDCFLLCSDGLSGMISDREIERIVSRQSEMGSQERVDYLVQRARDNGGL
CCCCHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
DNITVEIVEFSITPGSPSKPQRRKIGMIILTVILLICIGASGGYYFWNKHFKSESITIYK
CCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHH
SFMRRDTIIMLPEIKFQKGEDILEINYKQGHTEILMGKEKEKVIEINRALSSDSLKYDED
HHHHCCCEEEECCCCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCC
IDVAYGNRLLVFRQEFKNEQLRFSLADSVKIFKFVVPVVKDMTLTQPKQTHQESTPSVVN
CCEECCCEEEEEEHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHH
DVSNTANGSIVAIVAATGKVDSLTYRVDAQFVPKRKAFSFIEGENACFLVEGQSQPSKLN
HHCCCCCCCEEEEEEECCCCCEEEEEECCEECCCHHHHHEECCCCCEEEEECCCCHHHCC
RHFQITDIEYDATYFKKTKKETGFDISFTEKEPPKKIDIVIKGKEKEGENSTDVLLNIII
CCEEEEEEEECHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCCCCCHHHEEEEEEE
SLNINKEGK
EEEECCCCC
>Mature Secondary Structure
MKEENIYNYCHIAGRTDIGCKRQANEDSMGNFETINGLAAVVCDGMGGHVGGATASRLAV
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCEEEEEECCCCCCCCCCHHHHHHH
EAIHGFLDGQYYEDPREAIGEAIDAANKAILHQAMIQPELQGMGSTCVLLLVRDSKVYIG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEEEEECCEEEEE
HVGDSRVYLIRNRCIKQLTKDHSYVQMLVDMGQLTNEQAEHHPRKNEITNALGIANMKPA
ECCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCCCCCCC
TVLPDAILPEAGDCFLLCSDGLSGMISDREIERIVSRQSEMGSQERVDYLVQRARDNGGL
CCCCHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
DNITVEIVEFSITPGSPSKPQRRKIGMIILTVILLICIGASGGYYFWNKHFKSESITIYK
CCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHH
SFMRRDTIIMLPEIKFQKGEDILEINYKQGHTEILMGKEKEKVIEINRALSSDSLKYDED
HHHHCCCEEEECCCCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCC
IDVAYGNRLLVFRQEFKNEQLRFSLADSVKIFKFVVPVVKDMTLTQPKQTHQESTPSVVN
CCEECCCEEEEEEHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHH
DVSNTANGSIVAIVAATGKVDSLTYRVDAQFVPKRKAFSFIEGENACFLVEGQSQPSKLN
HHCCCCCCCEEEEEEECCCCCEEEEEECCEECCCHHHHHEECCCCCEEEEECCCCHHHCC
RHFQITDIEYDATYFKKTKKETGFDISFTEKEPPKKIDIVIKGKEKEGENSTDVLLNIII
CCEEEEEEEECHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCCCCCHHHEEEEEEE
SLNINKEGK
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]