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The map label for this gene is hutU [H]

Identifier: 29348103

GI number: 29348103

Start: 3356866

End: 3358857

Strand: Reverse

Name: hutU [H]

Synonym: BT_2694

Alternate gene names: 29348103

Gene position: 3358857-3356866 (Counterclockwise)

Preceding gene: 29348104

Following gene: 29348102

Centisome position: 53.65

GC content: 50.3

Gene sequence:

>1992_bases
ATGAAGATAACTCTTGGCAACACGTTACCTCCCTACCCAGCTTTCATAGAAGGTATCCGGAGGGCCCCCGACCGTAGTTA
TATGCTTACGCCGGCGCAGACAGCTACGGCATTGAAGAATGCATTGCGCTATATCCCCTTGGAATTGCATGAGCAACTGG
CACCTGAATTTATGGAAGAATTGCGTACCCGTGGGCGAATTTACGGATACCGCTTCCGCCCCGCAGGCGATCTGAAAGCC
AGACCGATTGATGAATATCGTGGCAAATGTGTGGAAGGCAAAGCCTTTCAAGTAATGATTGACAACAATCTCTGTTTTGA
TATCGCGTTGTATCCCTATGAGCTTGTTACTTATGGTGAAACCGGACAAGTTTGTCAGAACTGGATGCAATACCTTCTGA
TCAAGCAATATCTCGAAGAACTTACTCCTGAGCAAACACTGGTCATTGAGTCCGGACATCCGTTGGGACTGTTTCGTTCC
CGTCCCGATGCTCCCCGCGTTATTATTACCAACTCTATGATGATAGGCCAGTTCGACAATCAGCACGATTGGCACATTGC
CGCACAAATGGGAGTTGCCAACTATGGGCAGATGACGGCGGGCGGCTGGATGTATATCGGTCCGCAGGGTATTGTTCATG
GCACTTTCAACACATTACTCAACGCCGGGCGATTGAAACTCGGCATTCCGCAGGACAAAGATTTGCGTGGTCACCTCTTC
GTATCTTCCGGTTTGGGAGGAATGAGCGGGGCACAGCCAAAGGCAGCCGAAATAGCCGGAGCAGCCTCTATTATAGCCGA
AGTCGATAGCTCCCGTATCGAAACACGTTATCGGCAGGGATGGGTAGGCCATGTCACACAGGACCTGTCGGAAGCTTTCC
GCCTGGCAAAAGAAGCGATGGAACGTCGGGAACCTTGCTCGATAGCCTATCATGGCAACGTCGTTGATTTGCTGGAATAT
GCGGAACGCGAGCAGATTCATATTGAACTTTTGTCCGATCAGACCTCTTGTCATGCCGTTTACGAAGGAGGCTACTGTCC
CGTAGGCTTGACTTTCGAAGAGCGCACCCGCCTTCTTCATGAATCTCCTGATCAGTTCCGTCGTCTGGCAGACGCTTCTT
TGCGCCGCCATTTTGAGGTAATCCGGAAACTGGTGGCATGCGGCACTTACTTCTTCGATTATGGCAACTCCTTTATGAAA
GCGATTTATGATGCCGGAGTGAAAGAGATTTCCCGCAATGGAGTTGATGAGAAAGACGGATTTATATGGCCGAGTTATGT
AGAAGATATCATGGGACCCCAACTCTTTGATTATGGCTATGGCCCCTTCCGATGGGTATGTCTGAGCGGTAGGCACGAAG
ATCTGATAAAAACGGACCGTGCCGCAATGGAGTGCATTGATGTCAATCGCCGGGGACAGGATCTGGATAATTATAACTGG
ATACGCGACGCCGAAAAGAACAGGCTGGTAGTAGGTACTCAGGCACGTATTCTCTATCAGGATGCCGTAGGAAGAATGAA
TATCGCCCTCCGTTTCAATGAAATGGTACGGCGGGGAGAAGTAGGACCGATCATGTTGGGCCGCGATCATCATGATGTGA
GTGGAACCGATTCGCCTTTCCGTGAGACATCGAATATCAAAGACGGAAGTAATGTCATGGCTGATATGGCCGTGCAGTGT
TTCGCCGGAAACTGCGCGCGTGGCATGAGCTTGGTAGCCCTGCATAATGGCGGCGGAGTCGGTATCGGAAAAGCGATTAA
TGGCGGCTTCGGCATGGTATGTGACGGCAGCGAACGGGTAGACGAGATACTTCGCTCGGCTATGCTTTGGGATGTGATGG
GCGGAGTGGCCCGCCGTTCGTGGGCCCGCAATCCGCATGCAATGGAAACTAGTGACGCTTTCAATGAATCACATTCGGAA
GGGTATCATATAACGATGCCTTATCTGGCTGATGACGAGCTGATTAAAAAGACAATAAAAGAAGCATTGTAA

Upstream 100 bases:

>100_bases
AATCTACCAAAACCTTTGTCTTTTCTCTTCTTTTTTTCTATATTGCGAAGAGTTATAGAACTGTATTGCTTACAGTTTGT
AATCCTTAATTCTGCTTATT

Downstream 100 bases:

>100_bases
TAGAAAGTAACGAAATAGAGAAATAAATATGAATTGGAGTAAGATCATCGAATGTGTCCCCAACTTTAGCGAGGGACGTG
ATTTGGAGAAAATAGACAAG

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MKITLGNTLPPYPAFIEGIRRAPDRSYMLTPAQTATALKNALRYIPLELHEQLAPEFMEELRTRGRIYGYRFRPAGDLKA
RPIDEYRGKCVEGKAFQVMIDNNLCFDIALYPYELVTYGETGQVCQNWMQYLLIKQYLEELTPEQTLVIESGHPLGLFRS
RPDAPRVIITNSMMIGQFDNQHDWHIAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLGIPQDKDLRGHLF
VSSGLGGMSGAQPKAAEIAGAASIIAEVDSSRIETRYRQGWVGHVTQDLSEAFRLAKEAMERREPCSIAYHGNVVDLLEY
AEREQIHIELLSDQTSCHAVYEGGYCPVGLTFEERTRLLHESPDQFRRLADASLRRHFEVIRKLVACGTYFFDYGNSFMK
AIYDAGVKEISRNGVDEKDGFIWPSYVEDIMGPQLFDYGYGPFRWVCLSGRHEDLIKTDRAAMECIDVNRRGQDLDNYNW
IRDAEKNRLVVGTQARILYQDAVGRMNIALRFNEMVRRGEVGPIMLGRDHHDVSGTDSPFRETSNIKDGSNVMADMAVQC
FAGNCARGMSLVALHNGGGVGIGKAINGGFGMVCDGSERVDEILRSAMLWDVMGGVARRSWARNPHAMETSDAFNESHSE
GYHITMPYLADDELIKKTIKEAL

Sequences:

>Translated_663_residues
MKITLGNTLPPYPAFIEGIRRAPDRSYMLTPAQTATALKNALRYIPLELHEQLAPEFMEELRTRGRIYGYRFRPAGDLKA
RPIDEYRGKCVEGKAFQVMIDNNLCFDIALYPYELVTYGETGQVCQNWMQYLLIKQYLEELTPEQTLVIESGHPLGLFRS
RPDAPRVIITNSMMIGQFDNQHDWHIAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLGIPQDKDLRGHLF
VSSGLGGMSGAQPKAAEIAGAASIIAEVDSSRIETRYRQGWVGHVTQDLSEAFRLAKEAMERREPCSIAYHGNVVDLLEY
AEREQIHIELLSDQTSCHAVYEGGYCPVGLTFEERTRLLHESPDQFRRLADASLRRHFEVIRKLVACGTYFFDYGNSFMK
AIYDAGVKEISRNGVDEKDGFIWPSYVEDIMGPQLFDYGYGPFRWVCLSGRHEDLIKTDRAAMECIDVNRRGQDLDNYNW
IRDAEKNRLVVGTQARILYQDAVGRMNIALRFNEMVRRGEVGPIMLGRDHHDVSGTDSPFRETSNIKDGSNVMADMAVQC
FAGNCARGMSLVALHNGGGVGIGKAINGGFGMVCDGSERVDEILRSAMLWDVMGGVARRSWARNPHAMETSDAFNESHSE
GYHITMPYLADDELIKKTIKEAL
>Mature_663_residues
MKITLGNTLPPYPAFIEGIRRAPDRSYMLTPAQTATALKNALRYIPLELHEQLAPEFMEELRTRGRIYGYRFRPAGDLKA
RPIDEYRGKCVEGKAFQVMIDNNLCFDIALYPYELVTYGETGQVCQNWMQYLLIKQYLEELTPEQTLVIESGHPLGLFRS
RPDAPRVIITNSMMIGQFDNQHDWHIAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLGIPQDKDLRGHLF
VSSGLGGMSGAQPKAAEIAGAASIIAEVDSSRIETRYRQGWVGHVTQDLSEAFRLAKEAMERREPCSIAYHGNVVDLLEY
AEREQIHIELLSDQTSCHAVYEGGYCPVGLTFEERTRLLHESPDQFRRLADASLRRHFEVIRKLVACGTYFFDYGNSFMK
AIYDAGVKEISRNGVDEKDGFIWPSYVEDIMGPQLFDYGYGPFRWVCLSGRHEDLIKTDRAAMECIDVNRRGQDLDNYNW
IRDAEKNRLVVGTQARILYQDAVGRMNIALRFNEMVRRGEVGPIMLGRDHHDVSGTDSPFRETSNIKDGSNVMADMAVQC
FAGNCARGMSLVALHNGGGVGIGKAINGGFGMVCDGSERVDEILRSAMLWDVMGGVARRSWARNPHAMETSDAFNESHSE
GYHITMPYLADDELIKKTIKEAL

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=660, Percent_Identity=47.4242424242424, Blast_Score=573, Evalue=1e-163,
Organism=Homo sapiens, GI260306182, Length=382, Percent_Identity=45.0261780104712, Blast_Score=309, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI71997891, Length=651, Percent_Identity=49.7695852534562, Blast_Score=605, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 74493; Mature: 74493

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITLGNTLPPYPAFIEGIRRAPDRSYMLTPAQTATALKNALRYIPLELHEQLAPEFMEE
CEEECCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LRTRGRIYGYRFRPAGDLKARPIDEYRGKCVEGKAFQVMIDNNLCFDIALYPYELVTYGE
HHHCCCEEEEEECCCCCCCCCCCHHHCCCEECCCEEEEEECCCCEEEEEECCEEEEEECC
TGQVCQNWMQYLLIKQYLEELTPEQTLVIESGHPLGLFRSRPDAPRVIITNSMMIGQFDN
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCEEEEECCEEEECCCC
QHDWHIAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLGIPQDKDLRGHLF
CCCEEEEEECCCCCCCCCCCCCEEEECCCCEEEHHHHHHHCCCCEEECCCCCCCCCEEEE
VSSGLGGMSGAQPKAAEIAGAASIIAEVDSSRIETRYRQGWVGHVTQDLSEAFRLAKEAM
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERREPCSIAYHGNVVDLLEYAEREQIHIELLSDQTSCHAVYEGGYCPVGLTFEERTRLLH
HCCCCCEEEECCCHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCEECCHHHHHHHHH
ESPDQFRRLADASLRRHFEVIRKLVACGTYFFDYGNSFMKAIYDAGVKEISRNGVDEKDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FIWPSYVEDIMGPQLFDYGYGPFRWVCLSGRHEDLIKTDRAAMECIDVNRRGQDLDNYNW
EECHHHHHHHCCCCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IRDAEKNRLVVGTQARILYQDAVGRMNIALRFNEMVRRGEVGPIMLGRDHHDVSGTDSPF
HHCCCCCEEEEECCHHEEEHHCCCCEEEEEEEHHHHHCCCCCCEEECCCCCCCCCCCCCC
RETSNIKDGSNVMADMAVQCFAGNCARGMSLVALHNGGGVGIGKAINGGFGMVCDGSERV
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCCCEEEEECCHHHH
DEILRSAMLWDVMGGVARRSWARNPHAMETSDAFNESHSEGYHITMPYLADDELIKKTIK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHH
EAL
HCC
>Mature Secondary Structure
MKITLGNTLPPYPAFIEGIRRAPDRSYMLTPAQTATALKNALRYIPLELHEQLAPEFMEE
CEEECCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LRTRGRIYGYRFRPAGDLKARPIDEYRGKCVEGKAFQVMIDNNLCFDIALYPYELVTYGE
HHHCCCEEEEEECCCCCCCCCCCHHHCCCEECCCEEEEEECCCCEEEEEECCEEEEEECC
TGQVCQNWMQYLLIKQYLEELTPEQTLVIESGHPLGLFRSRPDAPRVIITNSMMIGQFDN
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCEEEEECCEEEECCCC
QHDWHIAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLGIPQDKDLRGHLF
CCCEEEEEECCCCCCCCCCCCCEEEECCCCEEEHHHHHHHCCCCEEECCCCCCCCCEEEE
VSSGLGGMSGAQPKAAEIAGAASIIAEVDSSRIETRYRQGWVGHVTQDLSEAFRLAKEAM
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERREPCSIAYHGNVVDLLEYAEREQIHIELLSDQTSCHAVYEGGYCPVGLTFEERTRLLH
HCCCCCEEEECCCHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCEECCHHHHHHHHH
ESPDQFRRLADASLRRHFEVIRKLVACGTYFFDYGNSFMKAIYDAGVKEISRNGVDEKDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FIWPSYVEDIMGPQLFDYGYGPFRWVCLSGRHEDLIKTDRAAMECIDVNRRGQDLDNYNW
EECHHHHHHHCCCCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IRDAEKNRLVVGTQARILYQDAVGRMNIALRFNEMVRRGEVGPIMLGRDHHDVSGTDSPF
HHCCCCCEEEEECCHHEEEHHCCCCEEEEEEEHHHHHCCCCCCEEECCCCCCCCCCCCCC
RETSNIKDGSNVMADMAVQCFAGNCARGMSLVALHNGGGVGIGKAINGGFGMVCDGSERV
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCCCEEEEECCHHHH
DEILRSAMLWDVMGGVARRSWARNPHAMETSDAFNESHSEGYHITMPYLADDELIKKTIK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHH
EAL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA