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The map label for this gene is hutI

Identifier: 29348101

GI number: 29348101

Start: 3354584

End: 3355837

Strand: Reverse

Name: hutI

Synonym: BT_2692

Alternate gene names: 29348101

Gene position: 3355837-3354584 (Counterclockwise)

Preceding gene: 29348102

Following gene: 29348100

Centisome position: 53.6

GC content: 50.56

Gene sequence:

>1254_bases
ATGAGTGAAAACCTGATTATATTCAATGCCCGTATTGTCACTCCGACAGGAACCTCCGCCCGTAAAGGTGCGGAAATGGG
ACAACTCCGTATCATAGAAAACGGAACGGTAGAAGTGACCAAAGGCATCATCACTTACGTCGGCGAGAGTCGTGGCGAAG
ATCGTGACGGCTACTACCAGCATTACTGGCATTACAACGCCCGGGGACATTGCCTGCTTCCGGGCTTTGTCGATTCGCAT
ACCCATTTTGTTTTTGGCGGAGAACGTTCCGAAGAATTTTCATGGCGGCTGAAAGGCGAAAGCTATATGTCCATCATGGA
ACGTGGCGGAGGGATAGCCAGTACCGTAAAAGCTACCCGGCAAATGAATTTCCTGAAACTTCGCTCGGCAGCCGAAGGCT
TTCTGAAGAAGATGAGTGCTATGGGAGTCACCACGGTAGAAGGTAAAAGCGGTTATGGACTCGATCGGGAAACAGAGCTG
CTGCAACTGAAAATAATGCGCAGCCTGAACAATGACGAGCACAAACGTATCGACATTGTATCCACTTTCTTAGGAGCCCA
CGCCCTTCCCGAAGAGTATAAAGGAAGAGGAGACGAATACATCGACTTTCTGATTCGTGAAATGCTCCCCGTTATCCGCG
AGAACGAACTTGCCGAATGTTGTGATGTCTTTTGCGAACAAGGAGTTTTCTCTGTCGAACAGTCCCGCCGCCTCCTTCAG
GCAGCCAAAGAACAAGGCTTCCTGTTAAAGCTCCATGCCGATGAAATCGTTTCCTTTGGTGGCGCTGAGCTGGCTGCCGA
ACTGGGCGCTTTGTCTGCCGATCATCTGCTTCAGGCTTCCGATGCCGGAATCCGTGCAATGGCCGACGCAGGAGTAGTAG
CTACCCTGCTGCCTCTGACGGCTTTCGCACTGAAAGAACCTTATGCACGCGGTCGTGAAATGATTGATGCCGGCTGTGCC
GTGGCACTTGCCACAGACTTGAATCCGGGAAGCTGTTTCTCCGGTTCCATCCCGTTGACCATTGCTTTGGCGTGTATTTA
CATGAAACTTAGCATCGAAGAAACCATCACTGCCCTTACACTGAACGGAGCTGCTGCCCTTCATCGGGCAGACCGGATCG
GAAGCATCGAAGTAGGCAAGCAAGGTGACTTTGTCATACTGAATTCGGACAATTATCACATTCTGCCATACTACGTAGGC
ATGAACTGTGTCATCATGACTATTAAAGGCGGTATGCTATACCCCGTCAATTGA

Upstream 100 bases:

>100_bases
TAGCACCCGGAGTATTAAAATAATGTGCGTCCGATATAAAGCTGCGGAAACTTATATCGAATTATGATTGAACTAATAAG
AACCGAATAATAAAAGATCA

Downstream 100 bases:

>100_bases
TAACTAAAAGCATAAAATACCATGTTAGCAGATTTAACCGTAAAAGATTTCTTAGATAAGGTAGCCGGCAATGATCCGGT
ACCCGGCGGTGGCAGTATTG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSENLIIFNARIVTPTGTSARKGAEMGQLRIIENGTVEVTKGIITYVGESRGEDRDGYYQHYWHYNARGHCLLPGFVDSH
THFVFGGERSEEFSWRLKGESYMSIMERGGGIASTVKATRQMNFLKLRSAAEGFLKKMSAMGVTTVEGKSGYGLDRETEL
LQLKIMRSLNNDEHKRIDIVSTFLGAHALPEEYKGRGDEYIDFLIREMLPVIRENELAECCDVFCEQGVFSVEQSRRLLQ
AAKEQGFLLKLHADEIVSFGGAELAAELGALSADHLLQASDAGIRAMADAGVVATLLPLTAFALKEPYARGREMIDAGCA
VALATDLNPGSCFSGSIPLTIALACIYMKLSIEETITALTLNGAAALHRADRIGSIEVGKQGDFVILNSDNYHILPYYVG
MNCVIMTIKGGMLYPVN

Sequences:

>Translated_417_residues
MSENLIIFNARIVTPTGTSARKGAEMGQLRIIENGTVEVTKGIITYVGESRGEDRDGYYQHYWHYNARGHCLLPGFVDSH
THFVFGGERSEEFSWRLKGESYMSIMERGGGIASTVKATRQMNFLKLRSAAEGFLKKMSAMGVTTVEGKSGYGLDRETEL
LQLKIMRSLNNDEHKRIDIVSTFLGAHALPEEYKGRGDEYIDFLIREMLPVIRENELAECCDVFCEQGVFSVEQSRRLLQ
AAKEQGFLLKLHADEIVSFGGAELAAELGALSADHLLQASDAGIRAMADAGVVATLLPLTAFALKEPYARGREMIDAGCA
VALATDLNPGSCFSGSIPLTIALACIYMKLSIEETITALTLNGAAALHRADRIGSIEVGKQGDFVILNSDNYHILPYYVG
MNCVIMTIKGGMLYPVN
>Mature_416_residues
SENLIIFNARIVTPTGTSARKGAEMGQLRIIENGTVEVTKGIITYVGESRGEDRDGYYQHYWHYNARGHCLLPGFVDSHT
HFVFGGERSEEFSWRLKGESYMSIMERGGGIASTVKATRQMNFLKLRSAAEGFLKKMSAMGVTTVEGKSGYGLDRETELL
QLKIMRSLNNDEHKRIDIVSTFLGAHALPEEYKGRGDEYIDFLIREMLPVIRENELAECCDVFCEQGVFSVEQSRRLLQA
AKEQGFLLKLHADEIVSFGGAELAAELGALSADHLLQASDAGIRAMADAGVVATLLPLTAFALKEPYARGREMIDAGCAV
ALATDLNPGSCFSGSIPLTIALACIYMKLSIEETITALTLNGAAALHRADRIGSIEVGKQGDFVILNSDNYHILPYYVGM
NCVIMTIKGGMLYPVN

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=342, Percent_Identity=43.5672514619883, Blast_Score=246, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17555004, Length=419, Percent_Identity=34.6062052505967, Blast_Score=238, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_BACTN (Q8A4B1)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_811604.1
- HSSP:   Q8U8Z6
- ProteinModelPortal:   Q8A4B1
- SMR:   Q8A4B1
- GeneID:   1072571
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_2692
- NMPDR:   fig|226186.1.peg.2691
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   BTHE226186:BT_2692-MONOMER
- BRENDA:   3.5.2.7
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 45701; Mature: 45570

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: BINDING 89-89 BINDING 102-102 BINDING 152-152 BINDING 187-187 BINDING 255-255

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENLIIFNARIVTPTGTSARKGAEMGQLRIIENGTVEVTKGIITYVGESRGEDRDGYYQ
CCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHCCCCCCCCCCCEE
HYWHYNARGHCLLPGFVDSHTHFVFGGERSEEFSWRLKGESYMSIMERGGGIASTVKATR
EEEEECCCCCEEECCCCCCCCEEEECCCCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHH
QMNFLKLRSAAEGFLKKMSAMGVTTVEGKSGYGLDRETELLQLKIMRSLNNDEHKRIDIV
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
STFLGAHALPEEYKGRGDEYIDFLIREMLPVIRENELAECCDVFCEQGVFSVEQSRRLLQ
HHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
AAKEQGFLLKLHADEIVSFGGAELAAELGALSADHLLQASDAGIRAMADAGVVATLLPLT
HHHHCCEEEEEEHHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCCEEHHCCCHHHHHHHHH
AFALKEPYARGREMIDAGCAVALATDLNPGSCFSGSIPLTIALACIYMKLSIEETITALT
HHHHHCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEE
LNGAAALHRADRIGSIEVGKQGDFVILNSDNYHILPYYVGMNCVIMTIKGGMLYPVN
ECCHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEEEEECCEEEEEEEECCEEEECC
>Mature Secondary Structure 
SENLIIFNARIVTPTGTSARKGAEMGQLRIIENGTVEVTKGIITYVGESRGEDRDGYYQ
CCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHCCCCCCCCCCCEE
HYWHYNARGHCLLPGFVDSHTHFVFGGERSEEFSWRLKGESYMSIMERGGGIASTVKATR
EEEEECCCCCEEECCCCCCCCEEEECCCCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHH
QMNFLKLRSAAEGFLKKMSAMGVTTVEGKSGYGLDRETELLQLKIMRSLNNDEHKRIDIV
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
STFLGAHALPEEYKGRGDEYIDFLIREMLPVIRENELAECCDVFCEQGVFSVEQSRRLLQ
HHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
AAKEQGFLLKLHADEIVSFGGAELAAELGALSADHLLQASDAGIRAMADAGVVATLLPLT
HHHHCCEEEEEEHHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCCEEHHCCCHHHHHHHHH
AFALKEPYARGREMIDAGCAVALATDLNPGSCFSGSIPLTIALACIYMKLSIEETITALT
HHHHHCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEE
LNGAAALHRADRIGSIEVGKQGDFVILNSDNYHILPYYVGMNCVIMTIKGGMLYPVN
ECCHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEEEEECCEEEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928