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The map label for this gene is nahA [H]

Identifier: 29347869

GI number: 29347869

Start: 3076578

End: 3078440

Strand: Reverse

Name: nahA [H]

Synonym: BT_2459

Alternate gene names: 29347869

Gene position: 3078440-3076578 (Counterclockwise)

Preceding gene: 29347870

Following gene: 29347868

Centisome position: 49.17

GC content: 42.4

Gene sequence:

>1863_bases
ATGGTCCGGAAAAAAGGTACGCTATCCATCGAACGTCTGGAAAGCATCCATTTCCCGGACGAATGGAAAAATACAGGAAA
CCTCCTTGTCAGCGATCTGAAAGAACTGGCAAATTTGTCTGTCATGGTGAATGCCTCAAATCCTTCCATTCATGTAAAAA
AGGTGAAAATGCAGGAGCCGGAAATGTACATGCTGGAAATTACAAAGCAGGGGATCATCATAGAAGCAGGTGACCAGACA
GGTATGATTCATGCTTTTTCCACTCTTTTACAATTGATTCTGGGAAGTGAGGGAAAAGAGTTACCCCGGTTCATAATCCA
CGACAAACCCCGTTTTAGTTACAGGGGAGTCATGATAGATTGTAGCCGCCATTTCTGGACTATCGAACAACTTAAAAAGT
ATACCAAACAATTGGCCTTTTTTAAACTTAACACTTTACATCTGCACTTGACAGACAATCAAGGCTGGCGTCTGTATCTG
GACCAATATCCGGATTTAGCGTTCAAAGGTACGTACTACCGGACATTCGAGGATCTATCGGGACATTATTATCGTAAAAG
CGAGTTGCAGGAATTGATCAACTATGCCGCCATGTACGGCATAGAGATCATTCCGGAGATTGACCTTCCGGGACACTGTC
TGGCCTTGCTTGCAGCCCTTCCCCAACTGTCATGTAAAGGCGGAAAATTTGAAGCCTATCCAGAGGAACTGGACGGACAA
AAACGGAAGAGAGCAGATGAGAATATGCTGTGTATAGGAAATCCTGAAACCTATAGGTTTGTGGAAAAACTGGTAGCAGA
ACTCACTGATCTCTTCCCTTCATCATTCATACATCTGGGAGGAGATGAAGTGTCGACACATCTATGGGAACAATGTCCGA
AATGCCAAAAGATTTACAAACAAGAGAATATGACTTCATGGCACGAGTTACAGGACTATTTTACGAAACGAGTTAGTGAA
ATTGTACGTTCCAAGGGAAAAAGGATGATAGGTTGGGATGAAATAAATGACCGTAATGCCGCTGACATCAGTGACGTGAT
CATGATCTGGCAACGTGATGGAAGAGAACAGCAACAGAAAGCTTTGAAAAGAGGGTTGTCAGTCATTATGTCTCCTAAGG
ATCCCTGTTACTTTGATTTCGGGTATTCACGGAATTCCACACGCAGATTGTATGAATGGGAACCAGTTGGCAAAGAATGT
ACGAATACTCAAGCACATCTCGTCAAGGGAGGACAGGCTAATTTGTGGACTGAATTCATTACAACCTCGGATGAGGTGGA
AAGGATGTTATATCCCAGAACTTGTGCCTTGGCCGAAACCCTCTGGAACACGAAAGAAAAGAAAGAATGGGAAGGGTTCC
GACAACGTATCAGCAAGTTCGGTGCTATTATGGAAAAACTGAATATCTGTTACTTCAAAGACGAGGATTGGGATAACACA
GGTTTTGTTCCGCAAAGCGAACAAAGGCCCCGTCTTGTATGTCCTGCCCGTATCGATACCAATATGAAGGGAATCAAGTA
TTATATGCCTGAATATGCGTTTGACGGTGATATACAGACTTTCTTTGCAACCCCCTATTCCTTAAAAAAAGGAGATTATT
TTACTCTTACTTTGGAAAAAAGACAAGCAGTACAGGAAATCAGAATTGTGTTTGATGTTTCAAAGGAACATCCGGAACAT
GTACAATTATCTGTCAGCGAGGACGGTACAATATTTAAGAAAGTAGCTGCAGATAACAAAAATGGAGAATTGTCAGCATC
TTTCAGTACACTAGCCATGATTAAAGCCCTCAAAATGGAATTGACAACTCCACTGATGGCCCGGCTGACTATCAAGGAGA
TTATCCTTCGCTACTATGAATAA

Upstream 100 bases:

>100_bases
TGGAAAGAGCTATATTTTTCACCTTTTTCTATTTCTTCTCATATTACCAGACAGTATTTATTCTCAAGATAATATTTGTC
TGATCCCGCAAGTTGAAAGC

Downstream 100 bases:

>100_bases
ACAAGTATAAGAATAATGAAAATTGTTATGATAAAAAAAATTATATATATTTCTCTCATCTGGATGGTATTTCACGGAGC
GAGTCTTCATGCTGCCAGTT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MVRKKGTLSIERLESIHFPDEWKNTGNLLVSDLKELANLSVMVNASNPSIHVKKVKMQEPEMYMLEITKQGIIIEAGDQT
GMIHAFSTLLQLILGSEGKELPRFIIHDKPRFSYRGVMIDCSRHFWTIEQLKKYTKQLAFFKLNTLHLHLTDNQGWRLYL
DQYPDLAFKGTYYRTFEDLSGHYYRKSELQELINYAAMYGIEIIPEIDLPGHCLALLAALPQLSCKGGKFEAYPEELDGQ
KRKRADENMLCIGNPETYRFVEKLVAELTDLFPSSFIHLGGDEVSTHLWEQCPKCQKIYKQENMTSWHELQDYFTKRVSE
IVRSKGKRMIGWDEINDRNAADISDVIMIWQRDGREQQQKALKRGLSVIMSPKDPCYFDFGYSRNSTRRLYEWEPVGKEC
TNTQAHLVKGGQANLWTEFITTSDEVERMLYPRTCALAETLWNTKEKKEWEGFRQRISKFGAIMEKLNICYFKDEDWDNT
GFVPQSEQRPRLVCPARIDTNMKGIKYYMPEYAFDGDIQTFFATPYSLKKGDYFTLTLEKRQAVQEIRIVFDVSKEHPEH
VQLSVSEDGTIFKKVAADNKNGELSASFSTLAMIKALKMELTTPLMARLTIKEIILRYYE

Sequences:

>Translated_620_residues
MVRKKGTLSIERLESIHFPDEWKNTGNLLVSDLKELANLSVMVNASNPSIHVKKVKMQEPEMYMLEITKQGIIIEAGDQT
GMIHAFSTLLQLILGSEGKELPRFIIHDKPRFSYRGVMIDCSRHFWTIEQLKKYTKQLAFFKLNTLHLHLTDNQGWRLYL
DQYPDLAFKGTYYRTFEDLSGHYYRKSELQELINYAAMYGIEIIPEIDLPGHCLALLAALPQLSCKGGKFEAYPEELDGQ
KRKRADENMLCIGNPETYRFVEKLVAELTDLFPSSFIHLGGDEVSTHLWEQCPKCQKIYKQENMTSWHELQDYFTKRVSE
IVRSKGKRMIGWDEINDRNAADISDVIMIWQRDGREQQQKALKRGLSVIMSPKDPCYFDFGYSRNSTRRLYEWEPVGKEC
TNTQAHLVKGGQANLWTEFITTSDEVERMLYPRTCALAETLWNTKEKKEWEGFRQRISKFGAIMEKLNICYFKDEDWDNT
GFVPQSEQRPRLVCPARIDTNMKGIKYYMPEYAFDGDIQTFFATPYSLKKGDYFTLTLEKRQAVQEIRIVFDVSKEHPEH
VQLSVSEDGTIFKKVAADNKNGELSASFSTLAMIKALKMELTTPLMARLTIKEIILRYYE
>Mature_620_residues
MVRKKGTLSIERLESIHFPDEWKNTGNLLVSDLKELANLSVMVNASNPSIHVKKVKMQEPEMYMLEITKQGIIIEAGDQT
GMIHAFSTLLQLILGSEGKELPRFIIHDKPRFSYRGVMIDCSRHFWTIEQLKKYTKQLAFFKLNTLHLHLTDNQGWRLYL
DQYPDLAFKGTYYRTFEDLSGHYYRKSELQELINYAAMYGIEIIPEIDLPGHCLALLAALPQLSCKGGKFEAYPEELDGQ
KRKRADENMLCIGNPETYRFVEKLVAELTDLFPSSFIHLGGDEVSTHLWEQCPKCQKIYKQENMTSWHELQDYFTKRVSE
IVRSKGKRMIGWDEINDRNAADISDVIMIWQRDGREQQQKALKRGLSVIMSPKDPCYFDFGYSRNSTRRLYEWEPVGKEC
TNTQAHLVKGGQANLWTEFITTSDEVERMLYPRTCALAETLWNTKEKKEWEGFRQRISKFGAIMEKLNICYFKDEDWDNT
GFVPQSEQRPRLVCPARIDTNMKGIKYYMPEYAFDGDIQTFFATPYSLKKGDYFTLTLEKRQAVQEIRIVFDVSKEHPEH
VQLSVSEDGTIFKKVAADNKNGELSASFSTLAMIKALKMELTTPLMARLTIKEIILRYYE

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=407, Percent_Identity=29.97542997543, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI189181666, Length=438, Percent_Identity=28.0821917808219, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17569815, Length=429, Percent_Identity=30.0699300699301, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24657468, Length=487, Percent_Identity=25.0513347022587, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17647501, Length=487, Percent_Identity=25.0513347022587, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281365639, Length=487, Percent_Identity=25.0513347022587, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24657474, Length=487, Percent_Identity=25.0513347022587, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45551090, Length=431, Percent_Identity=25.9860788863109, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24653074, Length=432, Percent_Identity=25.9259259259259, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI17933586, Length=430, Percent_Identity=23.953488372093, Blast_Score=112, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 72121; Mature: 72121

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKKGTLSIERLESIHFPDEWKNTGNLLVSDLKELANLSVMVNASNPSIHVKKVKMQEP
CCCCCCCCCHHHHHHCCCCHHHCCCCHHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCC
EMYMLEITKQGIIIEAGDQTGMIHAFSTLLQLILGSEGKELPRFIIHDKPRFSYRGVMID
CEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEECCEEEE
CSRHFWTIEQLKKYTKQLAFFKLNTLHLHLTDNQGWRLYLDQYPDLAFKGTYYRTFEDLS
CCCCEEEHHHHHHHHHHHHHEEEEEEEEEEECCCCCEEEEECCCCCEECCCHHHHHHHHC
GHYYRKSELQELINYAAMYGIEIIPEIDLPGHCLALLAALPQLSCKGGKFEAYPEELDGQ
CCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHCCCH
KRKRADENMLCIGNPETYRFVEKLVAELTDLFPSSFIHLGGDEVSTHLWEQCPKCQKIYK
HHHCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHCHHHHHHHH
QENMTSWHELQDYFTKRVSEIVRSKGKRMIGWDEINDRNAADISDVIMIWQRDGREQQQK
HCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHEEECCCCHHHHHH
ALKRGLSVIMSPKDPCYFDFGYSRNSTRRLYEWEPVGKECTNTQAHLVKGGQANLWTEFI
HHHHCHHEEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCHHHEEECCCCCHHHHHH
TTSDEVERMLYPRTCALAETLWNTKEKKEWEGFRQRISKFGAIMEKLNICYFKDEDWDNT
CCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
GFVPQSEQRPRLVCPARIDTNMKGIKYYMPEYAFDGDIQTFFATPYSLKKGDYFTLTLEK
CCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEEECCCEECCCCEEEEEEHH
RQAVQEIRIVFDVSKEHPEHVQLSVSEDGTIFKKVAADNKNGELSASFSTLAMIKALKME
HHHHHHHHHEEEECCCCCCEEEEEECCCCCEEHHHHCCCCCCCEEEHHHHHHHHHHHHHH
LTTPLMARLTIKEIILRYYE
HCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRKKGTLSIERLESIHFPDEWKNTGNLLVSDLKELANLSVMVNASNPSIHVKKVKMQEP
CCCCCCCCCHHHHHHCCCCHHHCCCCHHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCC
EMYMLEITKQGIIIEAGDQTGMIHAFSTLLQLILGSEGKELPRFIIHDKPRFSYRGVMID
CEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEECCEEEE
CSRHFWTIEQLKKYTKQLAFFKLNTLHLHLTDNQGWRLYLDQYPDLAFKGTYYRTFEDLS
CCCCEEEHHHHHHHHHHHHHEEEEEEEEEEECCCCCEEEEECCCCCEECCCHHHHHHHHC
GHYYRKSELQELINYAAMYGIEIIPEIDLPGHCLALLAALPQLSCKGGKFEAYPEELDGQ
CCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHCCCH
KRKRADENMLCIGNPETYRFVEKLVAELTDLFPSSFIHLGGDEVSTHLWEQCPKCQKIYK
HHHCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHCHHHHHHHH
QENMTSWHELQDYFTKRVSEIVRSKGKRMIGWDEINDRNAADISDVIMIWQRDGREQQQK
HCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHEEECCCCHHHHHH
ALKRGLSVIMSPKDPCYFDFGYSRNSTRRLYEWEPVGKECTNTQAHLVKGGQANLWTEFI
HHHHCHHEEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCHHHEEECCCCCHHHHHH
TTSDEVERMLYPRTCALAETLWNTKEKKEWEGFRQRISKFGAIMEKLNICYFKDEDWDNT
CCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
GFVPQSEQRPRLVCPARIDTNMKGIKYYMPEYAFDGDIQTFFATPYSLKKGDYFTLTLEK
CCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEEECCCEECCCCEEEEEEHH
RQAVQEIRIVFDVSKEHPEHVQLSVSEDGTIFKKVAADNKNGELSASFSTLAMIKALKME
HHHHHHHHHEEEECCCCCCEEEEEECCCCCEEHHHHCCCCCCCEEEHHHHHHHHHHHHHH
LTTPLMARLTIKEIILRYYE
HCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]