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The map label for this gene is arcB [H]

Identifier: 29347433

GI number: 29347433

Start: 2539054

End: 2541216

Strand: Reverse

Name: arcB [H]

Synonym: BT_2023

Alternate gene names: 29347433

Gene position: 2541216-2539054 (Counterclockwise)

Preceding gene: 29347434

Following gene: 29347431

Centisome position: 40.59

GC content: 52.24

Gene sequence:

>2163_bases
ATGGAAGCGCGGATAACTCGAAAAACAGCGGCACTTGCAATCTTTCTGATCAGTGCATTTCAGACTTACATTTATGCCGG
CCGCCCCTCTTCTTGTCAACTATTAATTATCAATTCTTATACCGAAAACTGTCTGTGGAGCGATGACTTTATGGCCCCTG
TCTATAAAGAGTTTCGCGTCCAGAACAGCCCGGTTGACATATGTGCCGAGCACATGGAACTGATGGCGACCGTTGTCCCG
GATATGCGCAAACAGGTCTTCATGTCCGACAGGCGCTGGATCAGTGCGCAATGCAGGAAAGAAGCGGAGGAAGTGATGCC
TTTCCTGTTGATCGGCGGCTATTTCTGGACAGATAGTGAAATAAAGAAACATCTGCTCCCGGTGATCAAAAGCCGCCTGG
ACGGAGCGTCGCATCCGCACAGAGTGGAAACGACAGCGATGGGGACGCCCCCATCCGTCATCAATTATGCCGACTACGTA
GAGAGCGGACTGTTGCTCGGCCTGTGTCCCGACGACACTGTTTTTGGTATGAAGCCCCCCACTTTTTTCGAGCGGAACAA
ATATTATCTGGCCCTGTTTTTCTCTTTGATGGCACTGGCCGTCATCTATGTGATATGGCTCCGGAGGGCGCTGCATGAGA
GGAGCAGGCTGCTGGAGATCATGAGGAGCTATAGCAGTCTGGTCGAAAACATGCCCGTTCTCTATGCCCGTGTCGAGCTC
ATATTCGACCCCGGTGGCCGGATTATCGACTATGTCTACCGGGAAGTGAATCCCACTTTCGAGAAATACATCCTGCCCAA
AGAAAAAATACTGGGAAAGAAATACAGCGAACTCAATCCGGATTATTCGCCGGAACTGCCCGACAGGTACAGCGAACTGA
ATGACAACAGGCAAATAACCTTTCAGTATTATCTGGAGAAGACGAAAACTCATCTGACCGTCATCTCCATACATTCCAAA
ACGAAAGGCTGCGTCGATGTCTTTGGTGTGGACAATACCGAACTGGTGCTGACGCAGCAAATGCTGAAATCCACCAACCA
TAAGTTGTCCGCCGCCCTCGACGCTGCCGACATGACCCCTTGGAAATGGGATTTGCGGACCGGCCTCCTCTCGTGCAACG
TCAGCCACGACTTGTACGTCACCGAAGAGGAGGTGACGCATGACGGCAACCTGATTATCGTGCCCACCTCCGCCTGTTTC
GCGAAAATCTGCGATGAAGACCGCGAACGCGTGCGGGACGCCTTCGAGCACCTCGCCAATGGCGAAACGCAGAAAATGCG
CGAGGAATATCGGGTAGGCAGACAGTGGCTTCCTTCCCCGCAACAGAATGAATGGGTAGAAGTGCGCGCAGCCGTGGACG
AGCGCGACGCGAACGGAAAACCGCTGAGCCTTATCGGCACTTCGATGACCGTCACCCAACGAAAGGAAATGGAGGAAGCG
CTCGTACAGGCAAAGGTGAAAGCCGAGGAGGCGAACACGCTCAAATCTTCTTTCCTCGCCAACATCAGCCACGAAATACG
CACTCCCCTCAACGCCATTGTCGGCTTTTCCTCGCTGCTGGTGTCGGCGGAAAGGGGGATTTCGGAAGAGAAACAGGAAT
ATATCAACATCATTGAAAACAACAACACACTCCTGTTGCAGCTTATCAGCGATGTGCTCGACCTTTCGAAGATCGAAGCC
GGAACGATGGAGTTCGACTACGCCCCGATAGATGTGCACGGCCTGTTTATCGAACTCGAAGATACGTTCCGGTTGAGGAA
TAAAAAGTCCGGCATCTGTATCTGCTATCACCGCCGGACGACCGAATGTGTCGTAAAGGCGGACCGTAACCGTCTGGTAC
AGGTGATGATGAATCTGATGAATAATGCTGTGAAGTTTACCGGGGAAGGCAGCATTGAGTTCGGGTTTGATGTGCGCGAA
GACGGTTTCCTGCATTTCTATGTCACCGACACCGGTTGCGGGATACCGGAGGAACGGTTGGAAGAAATCTTCGGGAATTT
TGTCAAACTCAACAGCTTTGTGCAGGGCACGGGACTCGGACTCACCATTTGCCGGGCAATCGTCGAAAGGATGGGAGGAA
AGATCGGTGCTGTCTCACGGCTGGGTCAGGGGAGTACTTTTTGGTTCACGCTGCCTTATACGGCCAACGAAGAGAAGATT
TGA

Upstream 100 bases:

>100_bases
CAGAACTTACATTTTTGTATAGTAATATTTAAAGATTTAATAGCAATATTTTAAGATATTCAGTGATCGGTTCCGCAAAC
AATCAAAACAATCACTATTT

Downstream 100 bases:

>100_bases
AAAGGACGTGGCGTGACGGAAATATACTTGCTTCCCGAAGAATGGGGCTTGACTAAAAAGTCAGCCCCTTCCCGAAGGGA
GGGGAAGCCATGCGGATAGT

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MEARITRKTAALAIFLISAFQTYIYAGRPSSCQLLIINSYTENCLWSDDFMAPVYKEFRVQNSPVDICAEHMELMATVVP
DMRKQVFMSDRRWISAQCRKEAEEVMPFLLIGGYFWTDSEIKKHLLPVIKSRLDGASHPHRVETTAMGTPPSVINYADYV
ESGLLLGLCPDDTVFGMKPPTFFERNKYYLALFFSLMALAVIYVIWLRRALHERSRLLEIMRSYSSLVENMPVLYARVEL
IFDPGGRIIDYVYREVNPTFEKYILPKEKILGKKYSELNPDYSPELPDRYSELNDNRQITFQYYLEKTKTHLTVISIHSK
TKGCVDVFGVDNTELVLTQQMLKSTNHKLSAALDAADMTPWKWDLRTGLLSCNVSHDLYVTEEEVTHDGNLIIVPTSACF
AKICDEDRERVRDAFEHLANGETQKMREEYRVGRQWLPSPQQNEWVEVRAAVDERDANGKPLSLIGTSMTVTQRKEMEEA
LVQAKVKAEEANTLKSSFLANISHEIRTPLNAIVGFSSLLVSAERGISEEKQEYINIIENNNTLLLQLISDVLDLSKIEA
GTMEFDYAPIDVHGLFIELEDTFRLRNKKSGICICYHRRTTECVVKADRNRLVQVMMNLMNNAVKFTGEGSIEFGFDVRE
DGFLHFYVTDTGCGIPEERLEEIFGNFVKLNSFVQGTGLGLTICRAIVERMGGKIGAVSRLGQGSTFWFTLPYTANEEKI

Sequences:

>Translated_720_residues
MEARITRKTAALAIFLISAFQTYIYAGRPSSCQLLIINSYTENCLWSDDFMAPVYKEFRVQNSPVDICAEHMELMATVVP
DMRKQVFMSDRRWISAQCRKEAEEVMPFLLIGGYFWTDSEIKKHLLPVIKSRLDGASHPHRVETTAMGTPPSVINYADYV
ESGLLLGLCPDDTVFGMKPPTFFERNKYYLALFFSLMALAVIYVIWLRRALHERSRLLEIMRSYSSLVENMPVLYARVEL
IFDPGGRIIDYVYREVNPTFEKYILPKEKILGKKYSELNPDYSPELPDRYSELNDNRQITFQYYLEKTKTHLTVISIHSK
TKGCVDVFGVDNTELVLTQQMLKSTNHKLSAALDAADMTPWKWDLRTGLLSCNVSHDLYVTEEEVTHDGNLIIVPTSACF
AKICDEDRERVRDAFEHLANGETQKMREEYRVGRQWLPSPQQNEWVEVRAAVDERDANGKPLSLIGTSMTVTQRKEMEEA
LVQAKVKAEEANTLKSSFLANISHEIRTPLNAIVGFSSLLVSAERGISEEKQEYINIIENNNTLLLQLISDVLDLSKIEA
GTMEFDYAPIDVHGLFIELEDTFRLRNKKSGICICYHRRTTECVVKADRNRLVQVMMNLMNNAVKFTGEGSIEFGFDVRE
DGFLHFYVTDTGCGIPEERLEEIFGNFVKLNSFVQGTGLGLTICRAIVERMGGKIGAVSRLGQGSTFWFTLPYTANEEKI
>Mature_720_residues
MEARITRKTAALAIFLISAFQTYIYAGRPSSCQLLIINSYTENCLWSDDFMAPVYKEFRVQNSPVDICAEHMELMATVVP
DMRKQVFMSDRRWISAQCRKEAEEVMPFLLIGGYFWTDSEIKKHLLPVIKSRLDGASHPHRVETTAMGTPPSVINYADYV
ESGLLLGLCPDDTVFGMKPPTFFERNKYYLALFFSLMALAVIYVIWLRRALHERSRLLEIMRSYSSLVENMPVLYARVEL
IFDPGGRIIDYVYREVNPTFEKYILPKEKILGKKYSELNPDYSPELPDRYSELNDNRQITFQYYLEKTKTHLTVISIHSK
TKGCVDVFGVDNTELVLTQQMLKSTNHKLSAALDAADMTPWKWDLRTGLLSCNVSHDLYVTEEEVTHDGNLIIVPTSACF
AKICDEDRERVRDAFEHLANGETQKMREEYRVGRQWLPSPQQNEWVEVRAAVDERDANGKPLSLIGTSMTVTQRKEMEEA
LVQAKVKAEEANTLKSSFLANISHEIRTPLNAIVGFSSLLVSAERGISEEKQEYINIIENNNTLLLQLISDVLDLSKIEA
GTMEFDYAPIDVHGLFIELEDTFRLRNKKSGICICYHRRTTECVVKADRNRLVQVMMNLMNNAVKFTGEGSIEFGFDVRE
DGFLHFYVTDTGCGIPEERLEEIFGNFVKLNSFVQGTGLGLTICRAIVERMGGKIGAVSRLGQGSTFWFTLPYTANEEKI

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=294, Percent_Identity=33.6734693877551, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=33.969465648855, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=36.4, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=32.8, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081816, Length=247, Percent_Identity=36.8421052631579, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=30.6772908366534, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=28.3842794759825, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=30.2127659574468, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=27.1929824561404, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=240, Percent_Identity=28.75, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=26.3374485596708, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=26.4069264069264, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=27.3127753303965, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788279, Length=223, Percent_Identity=26.9058295964126, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82169; Mature: 82169

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEARITRKTAALAIFLISAFQTYIYAGRPSSCQLLIINSYTENCLWSDDFMAPVYKEFRV
CCCCHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHC
QNSPVDICAEHMELMATVVPDMRKQVFMSDRRWISAQCRKEAEEVMPFLLIGGYFWTDSE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHCCCEEECHHH
IKKHLLPVIKSRLDGASHPHRVETTAMGTPPSVINYADYVESGLLLGLCPDDTVFGMKPP
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCC
TFFERNKYYLALFFSLMALAVIYVIWLRRALHERSRLLEIMRSYSSLVENMPVLYARVEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
IFDPGGRIIDYVYREVNPTFEKYILPKEKILGKKYSELNPDYSPELPDRYSELNDNRQIT
EECCCCHHHHHHHHHCCCCHHHHCCCHHHHHCCHHHHCCCCCCCCCCHHHHHCCCCCEEE
FQYYLEKTKTHLTVISIHSKTKGCVDVFGVDNTELVLTQQMLKSTNHKLSAALDAADMTP
EEEEEHHCCCEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCC
WKWDLRTGLLSCNVSHDLYVTEEEVTHDGNLIIVPTSACFAKICDEDRERVRDAFEHLAN
CEEEHHHCEEEECCCCCEEEEHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHC
GETQKMREEYRVGRQWLPSPQQNEWVEVRAAVDERDANGKPLSLIGTSMTVTQRKEMEEA
CCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCCCCEEEEECCCHHHHHHHHHHH
LVQAKVKAEEANTLKSSFLANISHEIRTPLNAIVGFSSLLVSAERGISEEKQEYINIIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
NNTLLLQLISDVLDLSKIEAGTMEFDYAPIDVHGLFIELEDTFRLRNKKSGICICYHRRT
CCEEHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEEEEEEHHHHHCCCCCCEEEEEECCC
TECVVKADRNRLVQVMMNLMNNAVKFTGEGSIEFGFDVREDGFLHFYVTDTGCGIPEERL
CHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEECCEECCCCEEEEEEECCCCCCCHHHH
EEIFGNFVKLNSFVQGTGLGLTICRAIVERMGGKIGAVSRLGQGSTFWFTLPYTANEEKI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEHHHHCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MEARITRKTAALAIFLISAFQTYIYAGRPSSCQLLIINSYTENCLWSDDFMAPVYKEFRV
CCCCHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHC
QNSPVDICAEHMELMATVVPDMRKQVFMSDRRWISAQCRKEAEEVMPFLLIGGYFWTDSE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHCCCEEECHHH
IKKHLLPVIKSRLDGASHPHRVETTAMGTPPSVINYADYVESGLLLGLCPDDTVFGMKPP
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCC
TFFERNKYYLALFFSLMALAVIYVIWLRRALHERSRLLEIMRSYSSLVENMPVLYARVEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
IFDPGGRIIDYVYREVNPTFEKYILPKEKILGKKYSELNPDYSPELPDRYSELNDNRQIT
EECCCCHHHHHHHHHCCCCHHHHCCCHHHHHCCHHHHCCCCCCCCCCHHHHHCCCCCEEE
FQYYLEKTKTHLTVISIHSKTKGCVDVFGVDNTELVLTQQMLKSTNHKLSAALDAADMTP
EEEEEHHCCCEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCC
WKWDLRTGLLSCNVSHDLYVTEEEVTHDGNLIIVPTSACFAKICDEDRERVRDAFEHLAN
CEEEHHHCEEEECCCCCEEEEHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHC
GETQKMREEYRVGRQWLPSPQQNEWVEVRAAVDERDANGKPLSLIGTSMTVTQRKEMEEA
CCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCCCCEEEEECCCHHHHHHHHHHH
LVQAKVKAEEANTLKSSFLANISHEIRTPLNAIVGFSSLLVSAERGISEEKQEYINIIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
NNTLLLQLISDVLDLSKIEAGTMEFDYAPIDVHGLFIELEDTFRLRNKKSGICICYHRRT
CCEEHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEEEEEEHHHHHCCCCCCEEEEEECCC
TECVVKADRNRLVQVMMNLMNNAVKFTGEGSIEFGFDVREDGFLHFYVTDTGCGIPEERL
CHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEECCEECCCCEEEEEEECCCCCCCHHHH
EEIFGNFVKLNSFVQGTGLGLTICRAIVERMGGKIGAVSRLGQGSTFWFTLPYTANEEKI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEHHHHCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]