Click here to switch to the map view.

The map label for this gene is 29347252

Identifier: 29347252

GI number: 29347252

Start: 2313348

End: 2314664

Strand: Reverse

Name: 29347252

Synonym: BT_1842

Alternate gene names: NA

Gene position: 2314664-2313348 (Counterclockwise)

Preceding gene: 29347253

Following gene: 29347251

Centisome position: 36.97

GC content: 45.79

Gene sequence:

>1317_bases
ATGAAAACACATTTCATCACTTTCCTATTATTAGTAGGTATGAGTCTGGGAATCTCCTCCCGGCTCCACGCACAGTCTTC
TTACCAGCCTGGTGAAGAAAACCTCAAAGCCCGTGAAGAATTTCAGGATAATAAATTCGGTATTTTCCTTCATTGGGGAC
TGTATGCCATGCTTGCCACCGGTGAGTGGACTATGACAAATAATAATCTGAATTATAAAGAGTATGCCAAACTGGCAGGC
GGTTTCTATCCCTCCAAGTTTGATGCGGATAAGTGGGTGGCTGCCATCAAAGCATCGGGAGCTAAATATATCTGTCTGAC
TTCCCGCCATCATGACGGCTTCTCCATGTTCGATACCCAATATTCGGACTTCAATATCGTGAAGGCAACTCCCTTTAAGC
GGGATATCATCAAGGAGCTGGCAGCAGCCTGTAGCAAACAGGGAATCAAACTTCATTTCTATTATTCTCATCTTGACTGG
ACGCGGGAAGATTATCCTTGGGGACGTACAGGACGGGGTACAGGACGTTCGAATCCGCAAGGAGACTGGAAAAGCTATTA
TCAGTTCATGAACAATCAGTTGACGGAACTGCTGACTAATTATGGTCCGGTAGGAGCCATTTGGTTTGACGGATGGTGGG
ATCAGGATGGAAACCCCGGCTTTAACTGGGAATTGCCGGAACAATATGCCATGATCCATAAACTACAGCCGGGCTGCCTG
ATAGGAAATAACCATCATCAGACTCCTTTTGCCGGTGAAGACATTCAGATATTCGAACGTGACCTGCCCGGAGAAAATAC
CGCAGGACTTTCCGGACAAAGTGTAAGTCACCTGCCCTTGGAAACCTGCGAAACGATGAATGGTATGTGGGGATATAAGA
TTACGGATCAGAATTATAAATCAACGAAGACACTGATTCATTATCTGGTAAAGGCAGCCGGAAAGAATGCGAACCTGTTG
ATGAATATCGGCCCTCAGCCCGACGGAGAGCTTCCGGAAGTAGCCGTACAGCGGTTGAAAGAAATGGGAGAGTGGATGAA
TCAATATGGTGAAACGATTTATGGAACCCGTGGCGGTGCGGTTGCTCCGCATGATTGGGGAGTGACGACGCAGAAAGGAA
ACAAGCTGTATGTGCATATTCTGAATTTGCAGGATAAAGCCCTGTTCCTGCCTTTGGCAGATAAGAAGGTGAAGAAGGCA
GTACTGTTTAAGAACGGCACACCTGTCCGATTCACTAAAAATAAAGAAGGCGTGTTGCTGGAGTTTACAGAGATACCAAA
AGATATTGATTACGTTGTAGAACTTACAATTGACTAA

Upstream 100 bases:

>100_bases
CTAGAATAACTTTGTTCTATAACTTAATGAGAGGCGGAGAAATGGAAATGACTCCGCCTTTTTGTTTTCTCTTTACCCCC
AATATTAACTATAACGCATT

Downstream 100 bases:

>100_bases
TTTTTAGCTAATTCTTCATAAAAGCATAGGGAAACTATCGTTACATACGTAGTTTCCCTTTATTTTTGGCAAACAATTTG
TTTATATAGATATAGAGTAA

Product: alpha-L-fucosidase

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Coagulation Factor 5/8 Type Domain Protein; Calx-Beta Domain-Containing Protein; Alpha-L-Fucosidase Protein; Alpha-1 3/4-Fucosidase; Exported Alpha-L-Fucosidase Protein; Lipoprotein; Exporte Hydrolase; Exported Fucosidase; Alpha-L-Fucosidase Family Protein; Coagulation Factor 5/8 Type Domain-Containing Protein; Alpha-L-Fucosidase-Like Protein; Glycoside Hydrolase Family Alpha-L-Fucosidase; Glycosyl Hydrolase Alpha-L-Fucosidase; Family; Exported Hydrolase; Ig Domain-Containing; Twin-Arginine Translocation Pathway Signal; Alpha-L-Fucosidase Superfamily; Fucosidase; DS Domain-Containing Protein; Tat Pathway Signal Sequence Domain Protein; Glycoside Hydrolase

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKTHFITFLLLVGMSLGISSRLHAQSSYQPGEENLKAREEFQDNKFGIFLHWGLYAMLATGEWTMTNNNLNYKEYAKLAG
GFYPSKFDADKWVAAIKASGAKYICLTSRHHDGFSMFDTQYSDFNIVKATPFKRDIIKELAAACSKQGIKLHFYYSHLDW
TREDYPWGRTGRGTGRSNPQGDWKSYYQFMNNQLTELLTNYGPVGAIWFDGWWDQDGNPGFNWELPEQYAMIHKLQPGCL
IGNNHHQTPFAGEDIQIFERDLPGENTAGLSGQSVSHLPLETCETMNGMWGYKITDQNYKSTKTLIHYLVKAAGKNANLL
MNIGPQPDGELPEVAVQRLKEMGEWMNQYGETIYGTRGGAVAPHDWGVTTQKGNKLYVHILNLQDKALFLPLADKKVKKA
VLFKNGTPVRFTKNKEGVLLEFTEIPKDIDYVVELTID

Sequences:

>Translated_438_residues
MKTHFITFLLLVGMSLGISSRLHAQSSYQPGEENLKAREEFQDNKFGIFLHWGLYAMLATGEWTMTNNNLNYKEYAKLAG
GFYPSKFDADKWVAAIKASGAKYICLTSRHHDGFSMFDTQYSDFNIVKATPFKRDIIKELAAACSKQGIKLHFYYSHLDW
TREDYPWGRTGRGTGRSNPQGDWKSYYQFMNNQLTELLTNYGPVGAIWFDGWWDQDGNPGFNWELPEQYAMIHKLQPGCL
IGNNHHQTPFAGEDIQIFERDLPGENTAGLSGQSVSHLPLETCETMNGMWGYKITDQNYKSTKTLIHYLVKAAGKNANLL
MNIGPQPDGELPEVAVQRLKEMGEWMNQYGETIYGTRGGAVAPHDWGVTTQKGNKLYVHILNLQDKALFLPLADKKVKKA
VLFKNGTPVRFTKNKEGVLLEFTEIPKDIDYVVELTID
>Mature_438_residues
MKTHFITFLLLVGMSLGISSRLHAQSSYQPGEENLKAREEFQDNKFGIFLHWGLYAMLATGEWTMTNNNLNYKEYAKLAG
GFYPSKFDADKWVAAIKASGAKYICLTSRHHDGFSMFDTQYSDFNIVKATPFKRDIIKELAAACSKQGIKLHFYYSHLDW
TREDYPWGRTGRGTGRSNPQGDWKSYYQFMNNQLTELLTNYGPVGAIWFDGWWDQDGNPGFNWELPEQYAMIHKLQPGCL
IGNNHHQTPFAGEDIQIFERDLPGENTAGLSGQSVSHLPLETCETMNGMWGYKITDQNYKSTKTLIHYLVKAAGKNANLL
MNIGPQPDGELPEVAVQRLKEMGEWMNQYGETIYGTRGGAVAPHDWGVTTQKGNKLYVHILNLQDKALFLPLADKKVKKA
VLFKNGTPVRFTKNKEGVLLEFTEIPKDIDYVVELTID

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40068512, Length=443, Percent_Identity=28.6681715575621, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI119360348, Length=463, Percent_Identity=23.7580993520518, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71997700, Length=369, Percent_Identity=28.1842818428184, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24662717, Length=370, Percent_Identity=29.1891891891892, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI78706642, Length=370, Percent_Identity=29.1891891891892, Blast_Score=118, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 49759; Mature: 49759

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTHFITFLLLVGMSLGISSRLHAQSSYQPGEENLKAREEFQDNKFGIFLHWGLYAMLAT
CCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEHHHCC
GEWTMTNNNLNYKEYAKLAGGFYPSKFDADKWVAAIKASGAKYICLTSRHHDGFSMFDTQ
CCEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
YSDFNIVKATPFKRDIIKELAAACSKQGIKLHFYYSHLDWTREDYPWGRTGRGTGRSNPQ
CCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GDWKSYYQFMNNQLTELLTNYGPVGAIWFDGWWDQDGNPGFNWELPEQYAMIHKLQPGCL
CHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCCCCHHHHHHHHCCCCEE
IGNNHHQTPFAGEDIQIFERDLPGENTAGLSGQSVSHLPLETCETMNGMWGYKITDQNYK
ECCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCCH
STKTLIHYLVKAAGKNANLLMNIGPQPDGELPEVAVQRLKEMGEWMNQYGETIYGTRGGA
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCC
VAPHDWGVTTQKGNKLYVHILNLQDKALFLPLADKKVKKAVLFKNGTPVRFTKNKEGVLL
CCCCCCCCEECCCCEEEEEEEECCCCEEEEECCCHHHHHEEEECCCCEEEEECCCCCEEE
EFTEIPKDIDYVVELTID
EHHHCCCCCEEEEEEEEC
>Mature Secondary Structure
MKTHFITFLLLVGMSLGISSRLHAQSSYQPGEENLKAREEFQDNKFGIFLHWGLYAMLAT
CCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEHHHCC
GEWTMTNNNLNYKEYAKLAGGFYPSKFDADKWVAAIKASGAKYICLTSRHHDGFSMFDTQ
CCEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
YSDFNIVKATPFKRDIIKELAAACSKQGIKLHFYYSHLDWTREDYPWGRTGRGTGRSNPQ
CCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GDWKSYYQFMNNQLTELLTNYGPVGAIWFDGWWDQDGNPGFNWELPEQYAMIHKLQPGCL
CHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCCCCHHHHHHHHCCCCEE
IGNNHHQTPFAGEDIQIFERDLPGENTAGLSGQSVSHLPLETCETMNGMWGYKITDQNYK
ECCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCCH
STKTLIHYLVKAAGKNANLLMNIGPQPDGELPEVAVQRLKEMGEWMNQYGETIYGTRGGA
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCC
VAPHDWGVTTQKGNKLYVHILNLQDKALFLPLADKKVKKAVLFKNGTPVRFTKNKEGVLL
CCCCCCCCEECCCCEEEEEEEECCCCEEEEECCCHHHHHEEEECCCCEEEEECCCCCEEE
EFTEIPKDIDYVVELTID
EHHHCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA