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The map label for this gene is 29347124

Identifier: 29347124

GI number: 29347124

Start: 2110471

End: 2111511

Strand: Reverse

Name: 29347124

Synonym: BT_1714

Alternate gene names: NA

Gene position: 2111511-2110471 (Counterclockwise)

Preceding gene: 29347125

Following gene: 29347123

Centisome position: 33.73

GC content: 34.68

Gene sequence:

>1041_bases
ATGAAGAATACTTATATTATTGGTGAAATAGGGCAGAATCATAATGGTTCTGTTGACTTGGCTAAGTTGATTATTGAATT
AATCTCACGACCTGTACATGAGGATGTTTTTGGTATGGATTTCATGCCAATGAATGCTGTTAAAATGACTAAAAGAGATT
TATCAGAAGAATTGGCTGTTTCTCAAATGAATCAAATATATGACAATCCTAATTCTTTTGGGCGTACTTATGGTGAACAT
CGTGCTTTTCTTGAGCTTGATGATCAAGCGCATTTTGAGATTTATAAATATGCTAAGTCATTAGGATTAGATTTTATCGA
GACGTTATGTGCCAAAGGATGTCTGTCTTTGCTTAAACTGTTCACACCGGATAGGCTAAAAGTTGCTAGTCGTGATTTGA
CTAACTTACCATTGCTTGAAGCATTAGCAGAAACTCATATTCCTATTATATTATCGACAGGAATGGCTGGTCAAAGAGAA
CTTGACAATGCATTAGATGTGATAACGAGATATCATAGTAATATAGCTATTCTACATTGTGTATCTCAGTATCCAACTCA
TCCAAATAATTTGAATCTACGTACAATAACATATTTGAAGAAGCATTACAATAAGTTTGAGATAGGTTTTTCTGATCATA
CAATAGGTATTTCTGCTGCTACAGCTGCTGTAGCGATGGGAGCGGAAATTATAGAAAAGCATGTAACAATTGATCGGCAT
ATGAAAGGAACAGACCAGCTTGGCTCTTTAGGTCCAGATGGGGTTAATCGTATGATTCGAGATATTCGCATAGCAGAGTG
TTGGCTTGGTACTGAAGATCTTTATATAGAAAAAGGGGTGGAGAAGTCTAAGATAAAACTTGAACGTTCTATTGCCACTC
GAAAATATATTCCAGCAGGTAGTATTATTCAAGAGTCGGACATTCATTTACTGAGTCCTGGTGATGGTTATAAATGGATA
GATAAAAAAAATGTAATTGGTCATTTTGCTAAACAAGATATATCAGCGAATGAAATAATATATCCTGATTTTATTGAATA
G

Upstream 100 bases:

>100_bases
AAAGAGTGGAAATATCGATAGAAGTGATTGTAGACTATGTTCGAAGACATGCAGAATACATTCAACTGATGAAACAACAA
ATAAAAAAAAATTCTAAATA

Downstream 100 bases:

>100_bases
ATATATTCCTACTGCAACTTGTATTACGGTATAGAGTACTGCCTGCTATAAGCTAAGTAGTGATTAATAAATAAGGGTAA
AATACTAAAAAAATGAAAGA

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEH
RAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRE
LDNALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATAAVAMGAEIIEKHVTIDRH
MKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVEKSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWI
DKKNVIGHFAKQDISANEIIYPDFIE

Sequences:

>Translated_346_residues
MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEH
RAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRE
LDNALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATAAVAMGAEIIEKHVTIDRH
MKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVEKSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWI
DKKNVIGHFAKQDISANEIIYPDFIE
>Mature_346_residues
MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEH
RAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRE
LDNALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATAAVAMGAEIIEKHVTIDRH
MKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVEKSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWI
DKKNVIGHFAKQDISANEIIYPDFIE

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=345, Percent_Identity=29.2753623188406, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI21357081, Length=252, Percent_Identity=32.9365079365079, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38957; Mature: 38957

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAV
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
SQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKL
HHHHHHHCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
FTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDNALDVITRYHSNIAILHC
CCCCHHHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEE
VSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATAAVAMGAEIIEKHVTIDRH
HHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
MKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVEKSKIKLERSIATRKYIPAG
CCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCC
SIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEIIYPDFIE
CCEECCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAV
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
SQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKL
HHHHHHHCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
FTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDNALDVITRYHSNIAILHC
CCCCHHHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEE
VSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATAAVAMGAEIIEKHVTIDRH
HHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
MKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVEKSKIKLERSIATRKYIPAG
CCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCC
SIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEIIYPDFIE
CCEECCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]