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The map label for this gene is atoC [H]

Identifier: 29346939

GI number: 29346939

Start: 1885379

End: 1886728

Strand: Reverse

Name: atoC [H]

Synonym: BT_1529

Alternate gene names: 29346939

Gene position: 1886728-1885379 (Counterclockwise)

Preceding gene: 29346940

Following gene: 29346938

Centisome position: 30.14

GC content: 50.0

Gene sequence:

>1350_bases
ATGATTTTAATAATAGACGACGACAGTGCGGTACGCTCTTCACTCAGTTTTATGTTGAAGCGGGCTGGATATGAAGCACA
AACGGTTTCCGGTCCCCGAGAAGCTATGGAGGTGGTGCGTTCCGTAGCACCGGATTTAATCTTAATGGATATGAACTTCA
CCCTTTCTACTACAGGTGAAGAAGGGCTGACTTTGCTCAGGCAAGTGAAAATATTCCGTCCGGAAACTCCGGTGATACTG
ATGACCGCCTGGGGAAGCATACAGCTTGCCGTGCAAGGTATGCAGGCAGGAGCCTTCGATTTTATCACCAAACCTTGGAA
TAATGCGGCATTGTTGCAACGTATCGAGACGGCTTTGGAACTGGCAGGCTCTCCCAAAGAGACAACGCAGGAACAGAATG
ACGCTTTCGACCGTCGTCATATCATCGGCCGTAGTCAGGGACTGACGGAAGTACTGAACACCATTGCCCGTATAGCAAAG
ACGAATGCTTCCGTACTGATCACCGGAGAAAGTGGGACGGGCAAGGAACTGATAGCCGAGGCGATACACATCAACAGCCA
GCGTGCCAAACAGCCTTTTGTCAAAGTGAACTTGGGAGGAATCTCCCAAAGTCTGTTCGAAAGTGAAATGTTCGGCCATA
AGAAAGGAGCTTTTACGGATGCTTCCTCCGACCGTATCGGACGCTTTGAGATGGCGAACAAAGGAACCATCTTTCTGGAC
GAGATCGGTGATCTCGACCCTTCTTGTCAAGTGAAGCTCTTGCGGGTGTTACAAGATCAGACGTTTGAAGTATTGGGAGA
CAGCCGTCCCCGTAAGACGGATATTCGTGTCGTCTCCGCTACCAATGCCGATTTACGCAAGATGGTGGGCGAACGTACTT
TCCGCGAAGATTTGTTTTACCGTATTAATCTGATTACCGTCAGACTGCCGGCTTTGCGTGAGCGTCGGGAGGATATTCCC
TTGCTGGCACGTCACTTTGCCGATCGTCAGGCAGAGGCCAACGGTTTTCCTCGCACCGAATTTTCGGCGGATGCCTTGCA
GTTTCTGAGTCGCTTACCTTATCCGGGAAATATCCGTGAATTGAAGAATCTGGTAGAACGTACGATTCTGGTCAATGGAA
AGCCGACGCTTGATGCCGCCGACTTTGATGCTCAGTATATCCGTCACGAAGATCAGAAAGTCGCCGAAGGCGCATCCTTT
GCTGGTATGACTCTGGATGAAATAGAACGGCAGACGATTTTGCAGGCTTTGGAGCGTCATAAGGGAAATTTGAGTCAGGT
AGCTACAGCGCTTGGCATCAGTCGTGCCGCCCTTTACCGTCGTTTGGAGAAGTTTGGAATCAGTGTTTAG

Upstream 100 bases:

>100_bases
AAGCAGATTTTGATGAAATAGTGCGGCAATAGGGATTAATCGGGCTATTTGTTGCTTGTATTGAGTATTTACAATATCTT
TGTCACAAGTAATTTAAACT

Downstream 100 bases:

>100_bases
CAGATAGACCTTACTATTATTATGCGTATAAAAGGATTTTTTGGTATACTCGTTTTCCTGCTTCTGGTCTTGGGGGGTGG
ATTGCTTTTCCTTTCAAGCC

Product: two-component system response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MILIIDDDSAVRSSLSFMLKRAGYEAQTVSGPREAMEVVRSVAPDLILMDMNFTLSTTGEEGLTLLRQVKIFRPETPVIL
MTAWGSIQLAVQGMQAGAFDFITKPWNNAALLQRIETALELAGSPKETTQEQNDAFDRRHIIGRSQGLTEVLNTIARIAK
TNASVLITGESGTGKELIAEAIHINSQRAKQPFVKVNLGGISQSLFESEMFGHKKGAFTDASSDRIGRFEMANKGTIFLD
EIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKTDIRVVSATNADLRKMVGERTFREDLFYRINLITVRLPALRERREDIP
LLARHFADRQAEANGFPRTEFSADALQFLSRLPYPGNIRELKNLVERTILVNGKPTLDAADFDAQYIRHEDQKVAEGASF
AGMTLDEIERQTILQALERHKGNLSQVATALGISRAALYRRLEKFGISV

Sequences:

>Translated_449_residues
MILIIDDDSAVRSSLSFMLKRAGYEAQTVSGPREAMEVVRSVAPDLILMDMNFTLSTTGEEGLTLLRQVKIFRPETPVIL
MTAWGSIQLAVQGMQAGAFDFITKPWNNAALLQRIETALELAGSPKETTQEQNDAFDRRHIIGRSQGLTEVLNTIARIAK
TNASVLITGESGTGKELIAEAIHINSQRAKQPFVKVNLGGISQSLFESEMFGHKKGAFTDASSDRIGRFEMANKGTIFLD
EIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKTDIRVVSATNADLRKMVGERTFREDLFYRINLITVRLPALRERREDIP
LLARHFADRQAEANGFPRTEFSADALQFLSRLPYPGNIRELKNLVERTILVNGKPTLDAADFDAQYIRHEDQKVAEGASF
AGMTLDEIERQTILQALERHKGNLSQVATALGISRAALYRRLEKFGISV
>Mature_449_residues
MILIIDDDSAVRSSLSFMLKRAGYEAQTVSGPREAMEVVRSVAPDLILMDMNFTLSTTGEEGLTLLRQVKIFRPETPVIL
MTAWGSIQLAVQGMQAGAFDFITKPWNNAALLQRIETALELAGSPKETTQEQNDAFDRRHIIGRSQGLTEVLNTIARIAK
TNASVLITGESGTGKELIAEAIHINSQRAKQPFVKVNLGGISQSLFESEMFGHKKGAFTDASSDRIGRFEMANKGTIFLD
EIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKTDIRVVSATNADLRKMVGERTFREDLFYRINLITVRLPALRERREDIP
LLARHFADRQAEANGFPRTEFSADALQFLSRLPYPGNIRELKNLVERTILVNGKPTLDAADFDAQYIRHEDQKVAEGASF
AGMTLDEIERQTILQALERHKGNLSQVATALGISRAALYRRLEKFGISV

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=455, Percent_Identity=42.1978021978022, Blast_Score=350, Evalue=8e-98,
Organism=Escherichia coli, GI1790437, Length=451, Percent_Identity=38.5809312638581, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI1790299, Length=475, Percent_Identity=38.3157894736842, Blast_Score=301, Evalue=8e-83,
Organism=Escherichia coli, GI1788905, Length=447, Percent_Identity=37.5838926174497, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI1789087, Length=310, Percent_Identity=43.8709677419355, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI87082117, Length=320, Percent_Identity=44.0625, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1789233, Length=344, Percent_Identity=39.5348837209302, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87082152, Length=335, Percent_Identity=38.5074626865672, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787583, Length=315, Percent_Identity=36.8253968253968, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87081872, Length=321, Percent_Identity=38.6292834890966, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1786524, Length=327, Percent_Identity=37.3088685015291, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1789828, Length=276, Percent_Identity=34.7826086956522, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI87081858, Length=290, Percent_Identity=29.6551724137931, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788394, Length=134, Percent_Identity=29.1044776119403, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789809, Length=131, Percent_Identity=30.5343511450382, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=28.3333333333333, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50022; Mature: 50022

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIIDDDSAVRSSLSFMLKRAGYEAQTVSGPREAMEVVRSVAPDLILMDMNFTLSTTGE
CEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEECCCH
EGLTLLRQVKIFRPETPVILMTAWGSIQLAVQGMQAGAFDFITKPWNNAALLQRIETALE
HHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHH
LAGSPKETTQEQNDAFDRRHIIGRSQGLTEVLNTIARIAKTNASVLITGESGTGKELIAE
HCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
AIHINSQRAKQPFVKVNLGGISQSLFESEMFGHKKGAFTDASSDRIGRFEMANKGTIFLD
HHHCCCHHHHCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEE
EIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKTDIRVVSATNADLRKMVGERTFREDLFY
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHE
RINLITVRLPALRERREDIPLLARHFADRQAEANGFPRTEFSADALQFLSRLPYPGNIRE
EEEEEEEECHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHH
LKNLVERTILVNGKPTLDAADFDAQYIRHEDQKVAEGASFAGMTLDEIERQTILQALERH
HHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
KGNLSQVATALGISRAALYRRLEKFGISV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILIIDDDSAVRSSLSFMLKRAGYEAQTVSGPREAMEVVRSVAPDLILMDMNFTLSTTGE
CEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEECCCH
EGLTLLRQVKIFRPETPVILMTAWGSIQLAVQGMQAGAFDFITKPWNNAALLQRIETALE
HHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHH
LAGSPKETTQEQNDAFDRRHIIGRSQGLTEVLNTIARIAKTNASVLITGESGTGKELIAE
HCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
AIHINSQRAKQPFVKVNLGGISQSLFESEMFGHKKGAFTDASSDRIGRFEMANKGTIFLD
HHHCCCHHHHCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEE
EIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKTDIRVVSATNADLRKMVGERTFREDLFY
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHE
RINLITVRLPALRERREDIPLLARHFADRQAEANGFPRTEFSADALQFLSRLPYPGNIRE
EEEEEEEECHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHH
LKNLVERTILVNGKPTLDAADFDAQYIRHEDQKVAEGASFAGMTLDEIERQTILQALERH
HHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
KGNLSQVATALGISRAALYRRLEKFGISV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]