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The map label for this gene is luxQ [H]

Identifier: 29346857

GI number: 29346857

Start: 1781157

End: 1783514

Strand: Reverse

Name: luxQ [H]

Synonym: BT_1447

Alternate gene names: 29346857

Gene position: 1783514-1781157 (Counterclockwise)

Preceding gene: 29346858

Following gene: 29346850

Centisome position: 28.49

GC content: 46.31

Gene sequence:

>2358_bases
ATGAACAACGAACAAACAAAAGAAGCACTGAAAGAGGAATTGGAGTTGCTTAGAAAAGAAAATGAGCAACTGAAGCGACA
ACTTCGATCTCTGGAACAGAATAAACAACCCGAAGAAAGCTCCACCAGCTTTCAGGAAAGGTATGCCGTTAAAATATTAA
ATTCCTTACCGGATATGCTGACTGTGTTCAACCACGACGAAGTGGGAATTGAAGTCGTATCCAATGAAGAAACCAATCAT
GTCGGGATATCCAACAAAGATTTTGAAGGAATGCACATGCGCCAGATGGTGCCTCCCGAAGCCTATCAGAACATCCATGC
CAATATGCAGAAAGTGATCGCCACGCGGACTGTTTCGGCAGCGCATCACGACATGGATTTCAATGGCTCTCACCATTACT
ACGAGAACCGGATTTTTCCGTTGGATGAAGAATACGTTCTGATTATGTGTCGTGACATCACGGAGAGAGTGGCCACCCAG
CAACAGCTGGAGATATTTAAAAGCGTACTCGACAAAGTCAGTGACAGCATTCTTGCCGTTTCCAGTGACGGAACGCTGGT
ATATGCCAACAAGCAATTTATGGAAGAGTATGGTGTCACCCAGCAGATGGGTACCCAGAAAATATACGACCTGCCCGTCT
CTATGCGCACGCCGGAGTTATGGGAAGCCAAACTGAAAGATATACGCGATAATGGCGGCAGCTTTTCATACCGTGCAGCG
TATGTGCGCAAAGGTGAGGAGAAAAACAGAGTACACCAAGTCTCTACCTACCTTACACAGGAGGATGATACGGAGCTTAT
CTGGTTTTTTACGCAGGACATTACCGATGTAATAAAGAAGCGGGATGAACTTCGTGAATTGAATCTCCTGCTGGACGGTA
TTCTGAATAATATCCCTGTCTATCTGTATGTGAAAGATCCCGAGGACGATTTCAGATATCTGTATTGGAACAAGGCATTT
GCCGAACATTCCAAGATTCCTGCCTCTCGGGCAATCGGCCGAACAGACTTTGAGATCTTTCCGGAGCGTGCAGATGCCGA
AAGGTTCCGCAGGGATGATTTGGAATTGATCCGGACGCATGAACGGATCGATATGCAGGAGACCTACGTGGCGGCCACCG
GCGAGACCCGTATTGTGCAGACACTGAAAGCGCTTGTCCCGATGGAAGGGCGCGAACCGCTTCTGATCGGTATCTCCTGG
GATATCACTAACTTTCAGAATATCGAGCAGGAACTGATTAAGGCACGCATCAAGGCAGAGCAATCCGACAGATTAAAAAC
CGCCTTTCTTGCAAATATGAGCCATGAAATCCGGACACCGCTGAATGCGATTGTCGGTTTCTCCAATTTGTTGCCTTCTG
CCGAAACCCTTGAAGAAGAAAAACTCTATTCGAGCATTATCAATCAGAACTCAGAGATCCTGTTGCAGCTGATTAATGAC
ATCTTGGATTTGTCTAAGATAGAAGCCGGTACATTGGAATACGTCAGACAGCCGATGAACCTGGGTGAAATATGTCGGAA
TATCTATCAGATTCATAAGGATCGTGTGCAGGAAGGGGTTACCCTTATTCTGGATAATCAAGACGAAGACCTGATTATTG
AAGAAGACCGGAACCGCATTGCGCAGGTTATCACTAACTTCCTCACCAATGCCGGTAAATTCACGCTTTCCGGTGAAATC
CGCTTTGGCTTTAAAGTCAATAATCAATGTATCCGTTTTTATGTGAAGGATACAGGTATCGGAATAGCTCCCGATAAGGT
GGGACATATTTTCGACCGTTTTGTCAAATTGAACTCATTTGCGCAGGGGACAGGTCTCGGACTTGCCATCTGCCGGATGA
TCATAGAAAAGATAGGAGGGGAGATCGGAGTCACTTCGGAAATAGGCAAAGGATCGACTTTCTACTTTACGATACCTTAT
AAAGAAAGCTCAGATGACCGTATTGCATTTTCCGAGGCTTCGGAAACGAAATACATCAGCCACACCATCAAGAGGATGCA
GAAGATCAAGAAGATTCTGGTAGCTGAAGATGTGGACAGCAACTTTGTACTGATCAAGAATATGATTGGCAAAGATTACA
CTCTGCTATGGGCGAAAGATGGCTTTGAGGCGGTGGAAATGTATAAACAGTTCCAGCCGGATTTGATTCTGATGGATATC
AAGATGCCTCGTATGGGTGGACTGGAGGCTACCCGCATCATTCGTTCCTATTCGAAGGAGATTCCTGTCATTGCGCTGAC
TGCCTATGCTTTCGAAGCGGACAAGGAGCAGGCTTTGGAAGCCGGCTGCAATGACTTTGTCACGAAGCCGGTTTCAAAAG
CAGCATTGGAAGAGGCGTTGGGGAAGTGTTGCGGGTAG

Upstream 100 bases:

>100_bases
ATTGAATGATTCTCAAAAAAAATAAAGGTGTTTTACGTACTTATCTCAAAAGTTTTCTTTACTTTTGGCAGATAAGTACG
TATTTATATCCGGATGTCTT

Downstream 100 bases:

>100_bases
TAACTACAAGTGATTATATTATACTCACTTTCCTATTTCGGGAACTAATAAGAACTTTGTTTCCGGAAAGTACTTTTCGA
GCCAAGCTCGTATAAACTCC

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MNNEQTKEALKEELELLRKENEQLKRQLRSLEQNKQPEESSTSFQERYAVKILNSLPDMLTVFNHDEVGIEVVSNEETNH
VGISNKDFEGMHMRQMVPPEAYQNIHANMQKVIATRTVSAAHHDMDFNGSHHYYENRIFPLDEEYVLIMCRDITERVATQ
QQLEIFKSVLDKVSDSILAVSSDGTLVYANKQFMEEYGVTQQMGTQKIYDLPVSMRTPELWEAKLKDIRDNGGSFSYRAA
YVRKGEEKNRVHQVSTYLTQEDDTELIWFFTQDITDVIKKRDELRELNLLLDGILNNIPVYLYVKDPEDDFRYLYWNKAF
AEHSKIPASRAIGRTDFEIFPERADAERFRRDDLELIRTHERIDMQETYVAATGETRIVQTLKALVPMEGREPLLIGISW
DITNFQNIEQELIKARIKAEQSDRLKTAFLANMSHEIRTPLNAIVGFSNLLPSAETLEEEKLYSSIINQNSEILLQLIND
ILDLSKIEAGTLEYVRQPMNLGEICRNIYQIHKDRVQEGVTLILDNQDEDLIIEEDRNRIAQVITNFLTNAGKFTLSGEI
RFGFKVNNQCIRFYVKDTGIGIAPDKVGHIFDRFVKLNSFAQGTGLGLAICRMIIEKIGGEIGVTSEIGKGSTFYFTIPY
KESSDDRIAFSEASETKYISHTIKRMQKIKKILVAEDVDSNFVLIKNMIGKDYTLLWAKDGFEAVEMYKQFQPDLILMDI
KMPRMGGLEATRIIRSYSKEIPVIALTAYAFEADKEQALEAGCNDFVTKPVSKAALEEALGKCCG

Sequences:

>Translated_785_residues
MNNEQTKEALKEELELLRKENEQLKRQLRSLEQNKQPEESSTSFQERYAVKILNSLPDMLTVFNHDEVGIEVVSNEETNH
VGISNKDFEGMHMRQMVPPEAYQNIHANMQKVIATRTVSAAHHDMDFNGSHHYYENRIFPLDEEYVLIMCRDITERVATQ
QQLEIFKSVLDKVSDSILAVSSDGTLVYANKQFMEEYGVTQQMGTQKIYDLPVSMRTPELWEAKLKDIRDNGGSFSYRAA
YVRKGEEKNRVHQVSTYLTQEDDTELIWFFTQDITDVIKKRDELRELNLLLDGILNNIPVYLYVKDPEDDFRYLYWNKAF
AEHSKIPASRAIGRTDFEIFPERADAERFRRDDLELIRTHERIDMQETYVAATGETRIVQTLKALVPMEGREPLLIGISW
DITNFQNIEQELIKARIKAEQSDRLKTAFLANMSHEIRTPLNAIVGFSNLLPSAETLEEEKLYSSIINQNSEILLQLIND
ILDLSKIEAGTLEYVRQPMNLGEICRNIYQIHKDRVQEGVTLILDNQDEDLIIEEDRNRIAQVITNFLTNAGKFTLSGEI
RFGFKVNNQCIRFYVKDTGIGIAPDKVGHIFDRFVKLNSFAQGTGLGLAICRMIIEKIGGEIGVTSEIGKGSTFYFTIPY
KESSDDRIAFSEASETKYISHTIKRMQKIKKILVAEDVDSNFVLIKNMIGKDYTLLWAKDGFEAVEMYKQFQPDLILMDI
KMPRMGGLEATRIIRSYSKEIPVIALTAYAFEADKEQALEAGCNDFVTKPVSKAALEEALGKCCG
>Mature_785_residues
MNNEQTKEALKEELELLRKENEQLKRQLRSLEQNKQPEESSTSFQERYAVKILNSLPDMLTVFNHDEVGIEVVSNEETNH
VGISNKDFEGMHMRQMVPPEAYQNIHANMQKVIATRTVSAAHHDMDFNGSHHYYENRIFPLDEEYVLIMCRDITERVATQ
QQLEIFKSVLDKVSDSILAVSSDGTLVYANKQFMEEYGVTQQMGTQKIYDLPVSMRTPELWEAKLKDIRDNGGSFSYRAA
YVRKGEEKNRVHQVSTYLTQEDDTELIWFFTQDITDVIKKRDELRELNLLLDGILNNIPVYLYVKDPEDDFRYLYWNKAF
AEHSKIPASRAIGRTDFEIFPERADAERFRRDDLELIRTHERIDMQETYVAATGETRIVQTLKALVPMEGREPLLIGISW
DITNFQNIEQELIKARIKAEQSDRLKTAFLANMSHEIRTPLNAIVGFSNLLPSAETLEEEKLYSSIINQNSEILLQLIND
ILDLSKIEAGTLEYVRQPMNLGEICRNIYQIHKDRVQEGVTLILDNQDEDLIIEEDRNRIAQVITNFLTNAGKFTLSGEI
RFGFKVNNQCIRFYVKDTGIGIAPDKVGHIFDRFVKLNSFAQGTGLGLAICRMIIEKIGGEIGVTSEIGKGSTFYFTIPY
KESSDDRIAFSEASETKYISHTIKRMQKIKKILVAEDVDSNFVLIKNMIGKDYTLLWAKDGFEAVEMYKQFQPDLILMDI
KMPRMGGLEATRIIRSYSKEIPVIALTAYAFEADKEQALEAGCNDFVTKPVSKAALEEALGKCCG

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=413, Percent_Identity=32.2033898305085, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1788713, Length=420, Percent_Identity=28.5714285714286, Blast_Score=164, Evalue=3e-41,
Organism=Escherichia coli, GI87081816, Length=398, Percent_Identity=28.391959798995, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=35.6862745098039, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1789149, Length=247, Percent_Identity=36.0323886639676, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=29.4605809128631, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=26.5560165975104, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=28.7671232876712, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=210, Percent_Identity=27.1428571428571, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=28.2700421940928, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=25.1121076233184, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788550, Length=110, Percent_Identity=34.5454545454545, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787487, Length=109, Percent_Identity=37.6146788990826, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790567, Length=135, Percent_Identity=34.0740740740741, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=125, Percent_Identity=34.4, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=110, Percent_Identity=33.6363636363636, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 90090; Mature: 90090

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNEQTKEALKEELELLRKENEQLKRQLRSLEQNKQPEESSTSFQERYAVKILNSLPDML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHH
TVFNHDEVGIEVVSNEETNHVGISNKDFEGMHMRQMVPPEAYQNIHANMQKVIATRTVSA
HHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AHHDMDFNGSHHYYENRIFPLDEEYVLIMCRDITERVATQQQLEIFKSVLDKVSDSILAV
HHCCCCCCCCCCEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
SSDGTLVYANKQFMEEYGVTQQMGTQKIYDLPVSMRTPELWEAKLKDIRDNGGSFSYRAA
ECCCEEEEECHHHHHHHCCHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEHH
YVRKGEEKNRVHQVSTYLTQEDDTELIWFFTQDITDVIKKRDELRELNLLLDGILNNIPV
HHHCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
YLYVKDPEDDFRYLYWNKAFAEHSKIPASRAIGRTDFEIFPERADAERFRRDDLELIRTH
EEEEECCCCCCEEEEECHHHHHHHCCCHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHH
ERIDMQETYVAATGETRIVQTLKALVPMEGREPLLIGISWDITNFQNIEQELIKARIKAE
HHCCHHHHEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCC
QSDRLKTAFLANMSHEIRTPLNAIVGFSNLLPSAETLEEEKLYSSIINQNSEILLQLIND
HHHHHHHHHHHHCCHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
ILDLSKIEAGTLEYVRQPMNLGEICRNIYQIHKDRVQEGVTLILDNQDEDLIIEEDRNRI
HHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHH
AQVITNFLTNAGKFTLSGEIRFGFKVNNQCIRFYVKDTGIGIAPDKVGHIFDRFVKLNSF
HHHHHHHHCCCCCEEEECEEEEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCC
AQGTGLGLAICRMIIEKIGGEIGVTSEIGKGSTFYFTIPYKESSDDRIAFSEASETKYIS
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHH
HTIKRMQKIKKILVAEDVDSNFVLIKNMIGKDYTLLWAKDGFEAVEMYKQFQPDLILMDI
HHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEE
KMPRMGGLEATRIIRSYSKEIPVIALTAYAFEADKEQALEAGCNDFVTKPVSKAALEEAL
CCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCHHHHHHCCCHHHHHCHHHHHHHHHHH
GKCCG
HHHCC
>Mature Secondary Structure
MNNEQTKEALKEELELLRKENEQLKRQLRSLEQNKQPEESSTSFQERYAVKILNSLPDML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHH
TVFNHDEVGIEVVSNEETNHVGISNKDFEGMHMRQMVPPEAYQNIHANMQKVIATRTVSA
HHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AHHDMDFNGSHHYYENRIFPLDEEYVLIMCRDITERVATQQQLEIFKSVLDKVSDSILAV
HHCCCCCCCCCCEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
SSDGTLVYANKQFMEEYGVTQQMGTQKIYDLPVSMRTPELWEAKLKDIRDNGGSFSYRAA
ECCCEEEEECHHHHHHHCCHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEHH
YVRKGEEKNRVHQVSTYLTQEDDTELIWFFTQDITDVIKKRDELRELNLLLDGILNNIPV
HHHCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
YLYVKDPEDDFRYLYWNKAFAEHSKIPASRAIGRTDFEIFPERADAERFRRDDLELIRTH
EEEEECCCCCCEEEEECHHHHHHHCCCHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHH
ERIDMQETYVAATGETRIVQTLKALVPMEGREPLLIGISWDITNFQNIEQELIKARIKAE
HHCCHHHHEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCC
QSDRLKTAFLANMSHEIRTPLNAIVGFSNLLPSAETLEEEKLYSSIINQNSEILLQLIND
HHHHHHHHHHHHCCHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
ILDLSKIEAGTLEYVRQPMNLGEICRNIYQIHKDRVQEGVTLILDNQDEDLIIEEDRNRI
HHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHH
AQVITNFLTNAGKFTLSGEIRFGFKVNNQCIRFYVKDTGIGIAPDKVGHIFDRFVKLNSF
HHHHHHHHCCCCCEEEECEEEEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCC
AQGTGLGLAICRMIIEKIGGEIGVTSEIGKGSTFYFTIPYKESSDDRIAFSEASETKYIS
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHH
HTIKRMQKIKKILVAEDVDSNFVLIKNMIGKDYTLLWAKDGFEAVEMYKQFQPDLILMDI
HHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEE
KMPRMGGLEATRIIRSYSKEIPVIALTAYAFEADKEQALEAGCNDFVTKPVSKAALEEAL
CCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCHHHHHHCCCHHHHHCHHHHHHHHHHH
GKCCG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA