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The map label for this gene is udg [H]

Identifier: 29346751

GI number: 29346751

Start: 1666242

End: 1667555

Strand: Reverse

Name: udg [H]

Synonym: BT_1341

Alternate gene names: 29346751

Gene position: 1667555-1666242 (Counterclockwise)

Preceding gene: 29346752

Following gene: 29346750

Centisome position: 26.64

GC content: 36.53

Gene sequence:

>1314_bases
ATGAATATTGCAGTAGTAGGAACCGGATATGTTGGTTTAGTCTCAGGAGCATGTTTCTCGGAAATAGGAGTAAATGTTAC
ATGCATAGATGTTAATGAGAAGAAAATACAGGCTTTAAAAGATGGTAAAATTCCTATTTATGAGCCAGGCTTGGATGAAA
TAGTCCGTCGTAATTATCATGAAGGACGATTACATTTTGATACAGATATTACAACATGCTTAAATGAAGTAGAAATTGTT
TTCTGTGCAGTAGGAACTCCTCCAGATGAGGATGGTAGCGCAGATCTTAAGTATGTGTTAGAGGTCGCTCGTACTGTTGG
GAGTAACATGAATAAAAAATTGCTTTTCGTAACAAAATCTACGGTGCCAGTAGGAACAGCGAAGAAAGTAAAGGCAGCTA
TTCAAGACGAATTAAAGAAACGGGACCTAGATATTTCTTTTGATGTTGCAAGTAATCCTGAATTTTTGAAAGAGGGTGCA
GCTATTAAAGATTTTATGAGTCCAGATCGTGTTGTCGTAGGTATAGAATCAGAGGAAGCTAAGAGATTGATGACACTCTT
ATATCGACCATTGATGCTTAATAATTGCCGTATTCTTTTTACTGATATACCAAGTGCTGAAATGATAAAGTATGCTGCAA
ATTCTATGCTTGCAACTCGTATCAGTTTTATGAATGACATCGCTAATCTTTGTGCATTAGTAGGGGCTGATGTGAATATG
GTCCGTAAAGGTATTGGGGCGGATAGTCGAATCGGCAGTAAATTTCTTTATCCAGGCTGTGGTTATGGTGGATCATGTTT
TCCTAAAGACGTGAAAGCGTTAATAAAAACGGCTGAAATGAACGGCTATGAGATGAGAGTGCTTAAAGCTGTGGAAGAGG
TAAATGAACAGCAAAAACAAATTATATTCAAGAAACTTTCAGAATATTATGAAACAAAATTGATTGGAAAAAATGTTGGA
ATTTGGGGATTAGCTTTCAAACCTGAAACTGATGATATGCGTGAAGCACCTTCATTGGTTGTAATCCGAAAGTTGTTAGA
AGCTGGATGCAGAGTTCGAGTGTATGATCCTATTGCTATGGACGAGTGTTATCGTCAACTTGGTGATGCTGTAATATACG
CTACAGATATGTATGATGCGACTTTAAATACTGATGCTTTATTATTATTAACAGAATGGAAGCAATTTCGACTACCAAGT
TGGGAGGTGATAAAGAAAATAATGAAGTGTCCATTGATTATTGATGGTCGTAATATTTATGAGGCACAAGATATGGTAAA
TCTTGGTTTTGACTATGTATGTATTGGAAGATAG

Upstream 100 bases:

>100_bases
GATACAGGATTTAAGCCAGATACATCTTTGCTTGAGGGAGTGAGGAAAACAATAGATTGGTATTGTGATTTTTATAAATT
AGATAGTAAATAGTTGTATT

Downstream 100 bases:

>100_bases
TATTTTTATAAAAACTAATATATAAATGATTACTGCATCAATTGTAACATACCATCATCACTTTAAGGATATTCGTAAGG
TAATTGAATGTATATTGTCA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNIAVVGTGYVGLVSGACFSEIGVNVTCIDVNEKKIQALKDGKIPIYEPGLDEIVRRNYHEGRLHFDTDITTCLNEVEIV
FCAVGTPPDEDGSADLKYVLEVARTVGSNMNKKLLFVTKSTVPVGTAKKVKAAIQDELKKRDLDISFDVASNPEFLKEGA
AIKDFMSPDRVVVGIESEEAKRLMTLLYRPLMLNNCRILFTDIPSAEMIKYAANSMLATRISFMNDIANLCALVGADVNM
VRKGIGADSRIGSKFLYPGCGYGGSCFPKDVKALIKTAEMNGYEMRVLKAVEEVNEQQKQIIFKKLSEYYETKLIGKNVG
IWGLAFKPETDDMREAPSLVVIRKLLEAGCRVRVYDPIAMDECYRQLGDAVIYATDMYDATLNTDALLLLTEWKQFRLPS
WEVIKKIMKCPLIIDGRNIYEAQDMVNLGFDYVCIGR

Sequences:

>Translated_437_residues
MNIAVVGTGYVGLVSGACFSEIGVNVTCIDVNEKKIQALKDGKIPIYEPGLDEIVRRNYHEGRLHFDTDITTCLNEVEIV
FCAVGTPPDEDGSADLKYVLEVARTVGSNMNKKLLFVTKSTVPVGTAKKVKAAIQDELKKRDLDISFDVASNPEFLKEGA
AIKDFMSPDRVVVGIESEEAKRLMTLLYRPLMLNNCRILFTDIPSAEMIKYAANSMLATRISFMNDIANLCALVGADVNM
VRKGIGADSRIGSKFLYPGCGYGGSCFPKDVKALIKTAEMNGYEMRVLKAVEEVNEQQKQIIFKKLSEYYETKLIGKNVG
IWGLAFKPETDDMREAPSLVVIRKLLEAGCRVRVYDPIAMDECYRQLGDAVIYATDMYDATLNTDALLLLTEWKQFRLPS
WEVIKKIMKCPLIIDGRNIYEAQDMVNLGFDYVCIGR
>Mature_437_residues
MNIAVVGTGYVGLVSGACFSEIGVNVTCIDVNEKKIQALKDGKIPIYEPGLDEIVRRNYHEGRLHFDTDITTCLNEVEIV
FCAVGTPPDEDGSADLKYVLEVARTVGSNMNKKLLFVTKSTVPVGTAKKVKAAIQDELKKRDLDISFDVASNPEFLKEGA
AIKDFMSPDRVVVGIESEEAKRLMTLLYRPLMLNNCRILFTDIPSAEMIKYAANSMLATRISFMNDIANLCALVGADVNM
VRKGIGADSRIGSKFLYPGCGYGGSCFPKDVKALIKTAEMNGYEMRVLKAVEEVNEQQKQIIFKKLSEYYETKLIGKNVG
IWGLAFKPETDDMREAPSLVVIRKLLEAGCRVRVYDPIAMDECYRQLGDAVIYATDMYDATLNTDALLLLTEWKQFRLPS
WEVIKKIMKCPLIIDGRNIYEAQDMVNLGFDYVCIGR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=463, Percent_Identity=34.9892008639309, Blast_Score=244, Evalue=9e-65,
Organism=Homo sapiens, GI296040438, Length=366, Percent_Identity=34.9726775956284, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI296040443, Length=458, Percent_Identity=31.6593886462882, Blast_Score=191, Evalue=2e-48,
Organism=Escherichia coli, GI1788340, Length=367, Percent_Identity=28.3378746594005, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI48994968, Length=415, Percent_Identity=25.5421686746988, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=460, Percent_Identity=35.8695652173913, Blast_Score=247, Evalue=9e-66,
Organism=Drosophila melanogaster, GI17136908, Length=466, Percent_Identity=35.6223175965665, Blast_Score=252, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48726; Mature: 48726

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAVVGTGYVGLVSGACFSEIGVNVTCIDVNEKKIQALKDGKIPIYEPGLDEIVRRNYH
CEEEEEECCHHHHHCCHHHHHHCCEEEEEECCHHHHHHHHCCCCCEECCCHHHHHHCCCC
EGRLHFDTDITTCLNEVEIVFCAVGTPPDEDGSADLKYVLEVARTVGSNMNKKLLFVTKS
CCEEEECCHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEC
TVPVGTAKKVKAAIQDELKKRDLDISFDVASNPEFLKEGAAIKDFMSPDRVVVGIESEEA
CCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCHHHHHCCCCCEEEEECHHHH
KRLMTLLYRPLMLNNCRILFTDIPSAEMIKYAANSMLATRISFMNDIANLCALVGADVNM
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGADSRIGSKFLYPGCGYGGSCFPKDVKALIKTAEMNGYEMRVLKAVEEVNEQQKQ
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IIFKKLSEYYETKLIGKNVGIWGLAFKPETDDMREAPSLVVIRKLLEAGCRVRVYDPIAM
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEEECCHHH
DECYRQLGDAVIYATDMYDATLNTDALLLLTEWKQFRLPSWEVIKKIMKCPLIIDGRNIY
HHHHHHHCCEEEEEEECCCCCCCCCEEEEEECHHHHCCCCHHHHHHHHHCCEEECCCCCH
EAQDMVNLGFDYVCIGR
HHHHHHHCCCCEEEECC
>Mature Secondary Structure
MNIAVVGTGYVGLVSGACFSEIGVNVTCIDVNEKKIQALKDGKIPIYEPGLDEIVRRNYH
CEEEEEECCHHHHHCCHHHHHHCCEEEEEECCHHHHHHHHCCCCCEECCCHHHHHHCCCC
EGRLHFDTDITTCLNEVEIVFCAVGTPPDEDGSADLKYVLEVARTVGSNMNKKLLFVTKS
CCEEEECCHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEC
TVPVGTAKKVKAAIQDELKKRDLDISFDVASNPEFLKEGAAIKDFMSPDRVVVGIESEEA
CCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCHHHHHCCCCCEEEEECHHHH
KRLMTLLYRPLMLNNCRILFTDIPSAEMIKYAANSMLATRISFMNDIANLCALVGADVNM
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGADSRIGSKFLYPGCGYGGSCFPKDVKALIKTAEMNGYEMRVLKAVEEVNEQQKQ
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IIFKKLSEYYETKLIGKNVGIWGLAFKPETDDMREAPSLVVIRKLLEAGCRVRVYDPIAM
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEEECCHHH
DECYRQLGDAVIYATDMYDATLNTDALLLLTEWKQFRLPSWEVIKKIMKCPLIIDGRNIY
HHHHHHHCCEEEEEEECCCCCCCCCEEEEEECHHHHCCCCHHHHHHHHHCCEEECCCCCH
EAQDMVNLGFDYVCIGR
HHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]