Click here to switch to the map view.

The map label for this gene is rfbC [H]

Identifier: 29346748

GI number: 29346748

Start: 1663708

End: 1664256

Strand: Reverse

Name: rfbC [H]

Synonym: BT_1338

Alternate gene names: 29346748

Gene position: 1664256-1663708 (Counterclockwise)

Preceding gene: 29346749

Following gene: 29346747

Centisome position: 26.58

GC content: 34.61

Gene sequence:

>549_bases
ATGGAAGTTATAAAGACTAATATAGAGGGAGTCGTTATTATTGAACCTCGTATTTTTAAAGACGATCGTGGTTATTTCTT
TGAATCTTTTTCTCAAAGAGAATTTGAGGAAAAGGTTTGTAAAACGACTTTTGTTCAAGATAATGAAAGTAAGTCTAGCT
ATGGAGTATTGAGAGGCTTACATTTCCAGAAACCTCCTTTTGCTCAAAGTAAATTAGTGCGAGTTATAAAAGGAGCTGTG
TTAGATGTTGCTGTTGATATAAGAAAAGGCTCTCCTACATTTGGGCAATATGTATCTGTAGAATTAACAGGTGAAAATCA
TCGTCAGTTTTTTATACCTCGTGGATTTGCTCATGGATTTAGTGTTTTAAGTGAAGAAGTGATTTTCCAATATAAATGTG
ATAACTTCTATTCTCCTCAAAGTGAAGGGGCAATAGCATGGAATGATCCGGATTTGAATATTGATTGGCGTATTCCTGCT
GAAAAAGTGGTTCTCTCAGAGAAAGACAGTAAGCATCCAAGGTTAAAAGATTGGCAGAATATGTTTTAG

Upstream 100 bases:

>100_bases
ATATTGTTGTATGGGTTGGGCTTAATTTGTGGTGGAGTGGAGTGAGAAAAAAGCGATGCCATGGAGTTGGTAAATAGAAA
ATTGAGAGTTGTTTTAAGTG

Downstream 100 bases:

>100_bases
GATATTACTCCAATTACCTGCAATTCAGTTCTTAGAATTGAAATAAACGACGATTGGGAGCGTATTCTTGAACGAATGCA
CCGATAAAAAGAAAAAAACA

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MEVIKTNIEGVVIIEPRIFKDDRGYFFESFSQREFEEKVCKTTFVQDNESKSSYGVLRGLHFQKPPFAQSKLVRVIKGAV
LDVAVDIRKGSPTFGQYVSVELTGENHRQFFIPRGFAHGFSVLSEEVIFQYKCDNFYSPQSEGAIAWNDPDLNIDWRIPA
EKVVLSEKDSKHPRLKDWQNMF

Sequences:

>Translated_182_residues
MEVIKTNIEGVVIIEPRIFKDDRGYFFESFSQREFEEKVCKTTFVQDNESKSSYGVLRGLHFQKPPFAQSKLVRVIKGAV
LDVAVDIRKGSPTFGQYVSVELTGENHRQFFIPRGFAHGFSVLSEEVIFQYKCDNFYSPQSEGAIAWNDPDLNIDWRIPA
EKVVLSEKDSKHPRLKDWQNMF
>Mature_182_residues
MEVIKTNIEGVVIIEPRIFKDDRGYFFESFSQREFEEKVCKTTFVQDNESKSSYGVLRGLHFQKPPFAQSKLVRVIKGAV
LDVAVDIRKGSPTFGQYVSVELTGENHRQFFIPRGFAHGFSVLSEEVIFQYKCDNFYSPQSEGAIAWNDPDLNIDWRIPA
EKVVLSEKDSKHPRLKDWQNMF

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=172, Percent_Identity=54.0697674418605, Blast_Score=186, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17550412, Length=178, Percent_Identity=47.1910112359551, Blast_Score=149, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21061; Mature: 21061

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVIKTNIEGVVIIEPRIFKDDRGYFFESFSQREFEEKVCKTTFVQDNESKSSYGVLRGL
CCCEECCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCC
HFQKPPFAQSKLVRVIKGAVLDVAVDIRKGSPTFGQYVSVELTGENHRQFFIPRGFAHGF
CCCCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCHHHHH
SVLSEEVIFQYKCDNFYSPQSEGAIAWNDPDLNIDWRIPAEKVVLSEKDSKHPRLKDWQN
HHHHHHHEEEEECCCCCCCCCCCEEEECCCCCEEEEECCHHHEEECCCCCCCCCCCHHHH
MF
CC
>Mature Secondary Structure
MEVIKTNIEGVVIIEPRIFKDDRGYFFESFSQREFEEKVCKTTFVQDNESKSSYGVLRGL
CCCEECCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCC
HFQKPPFAQSKLVRVIKGAVLDVAVDIRKGSPTFGQYVSVELTGENHRQFFIPRGFAHGF
CCCCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCHHHHH
SVLSEEVIFQYKCDNFYSPQSEGAIAWNDPDLNIDWRIPAEKVVLSEKDSKHPRLKDWQN
HHHHHHHEEEEECCCCCCCCCCCEEEECCCCCEEEEECCHHHEEECCCCCCCCCCCHHHH
MF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8170390; 8157605; 12384590; 12704152 [H]