Click here to switch to the map view.

The map label for this gene is ribE [H]

Identifier: 29346727

GI number: 29346727

Start: 1642549

End: 1643151

Strand: Reverse

Name: ribE [H]

Synonym: BT_1317

Alternate gene names: 29346727

Gene position: 1643151-1642549 (Counterclockwise)

Preceding gene: 29346730

Following gene: 29346726

Centisome position: 26.25

GC content: 42.45

Gene sequence:

>603_bases
ATGTTTTCTGGAATCGTAGAAGAGTATGCTACCTTGGTAGCACTGGTGAAAGACCAGGAGAATATACACTTTACATTTAA
GTGTTCGTTTGTAAATGAGCTGAAGATTGATCAGAGTATTTCTCACAATGGAGTATGCCTGACGGTAGTGAACTTGACCG
ATGATACGTATACGGTAACTGCCATGAAAGAAACGTTGGACCGTTCGAATCTTGGTTTGCTGAAAGTGGGCGATAAGGTG
AATGTAGAGCGCAGCATGATGATGAATGGCCGTCTGGACGGACATATCGTACAGGGGCATGTGGACCAGACCGCTACTTG
TGTGGAAATAAAGGATGCGGACGGAAGCTGGTATTTTACATTCAAATACGCATTTGATAAGGAAATGGCGAAACGTGGCT
ATATCACAGTGGATAAGGGGTCAGTCACTGTAAATGGTGTCAGCTTGACGGTATGTAATCCGACGGATGATACTTTCCAG
GTAGCTATTATTCCTTATACTTATGAGCATACTAACTTTCATACGTTCGAGATCGGTAGCGTAGTGAACATTGAGTTTGA
TATCATCGGCAAGTATATCAGCCGGATGATTCAATATAAATAG

Upstream 100 bases:

>100_bases
AAAAAGCTAATATATTAGTATAGTTGGCTAAAAGGTTTAGAAGCTCTCTTATTTCCCTTTTTAGTCAGTCTTTTATTGTA
GAACATTAATAATTAACATT

Downstream 100 bases:

>100_bases
TCAATTGGGAATTGTTAGCTTCAATCGTAATTTATAAATCGTAAAACCCTAAATTGGATGGATTTTCTGCAATTAGTGTT
GTCTCGCCAAAGTGACCGGG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MFSGIVEEYATLVALVKDQENIHFTFKCSFVNELKIDQSISHNGVCLTVVNLTDDTYTVTAMKETLDRSNLGLLKVGDKV
NVERSMMMNGRLDGHIVQGHVDQTATCVEIKDADGSWYFTFKYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTDDTFQ
VAIIPYTYEHTNFHTFEIGSVVNIEFDIIGKYISRMIQYK

Sequences:

>Translated_200_residues
MFSGIVEEYATLVALVKDQENIHFTFKCSFVNELKIDQSISHNGVCLTVVNLTDDTYTVTAMKETLDRSNLGLLKVGDKV
NVERSMMMNGRLDGHIVQGHVDQTATCVEIKDADGSWYFTFKYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTDDTFQ
VAIIPYTYEHTNFHTFEIGSVVNIEFDIIGKYISRMIQYK
>Mature_200_residues
MFSGIVEEYATLVALVKDQENIHFTFKCSFVNELKIDQSISHNGVCLTVVNLTDDTYTVTAMKETLDRSNLGLLKVGDKV
NVERSMMMNGRLDGHIVQGHVDQTATCVEIKDADGSWYFTFKYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTDDTFQ
VAIIPYTYEHTNFHTFEIGSVVNIEFDIIGKYISRMIQYK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=190, Percent_Identity=36.8421052631579, Blast_Score=105, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319733, Length=209, Percent_Identity=34.9282296650718, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22570; Mature: 22570

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGIVEEYATLVALVKDQENIHFTFKCSFVNELKIDQSISHNGVCLTVVNLTDDTYTVT
CCCHHHHHHHHHEEEEECCCCEEEEEEEEEEEEEEECCCCCCCCEEEEEEEECCCEEEEE
AMKETLDRSNLGLLKVGDKVNVERSMMMNGRLDGHIVQGHVDQTATCVEIKDADGSWYFT
EEHHHCCCCCCCEEEECCCCCCCEEEEECCCCCCEEEECCCCCCEEEEEEEECCCCEEEE
FKYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTDDTFQVAIIPYTYEHTNFHTFEIGS
EEEEECHHHHHCCCEEEECCCEEEEEEEEEEECCCCCCEEEEEEEEEEECCCEEEEECCC
VVNIEFDIIGKYISRMIQYK
EEEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSGIVEEYATLVALVKDQENIHFTFKCSFVNELKIDQSISHNGVCLTVVNLTDDTYTVT
CCCHHHHHHHHHEEEEECCCCEEEEEEEEEEEEEEECCCCCCCCEEEEEEEECCCEEEEE
AMKETLDRSNLGLLKVGDKVNVERSMMMNGRLDGHIVQGHVDQTATCVEIKDADGSWYFT
EEHHHCCCCCCCEEEECCCCCCCEEEEECCCCCCEEEECCCCCCEEEEEEEECCCCEEEE
FKYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTDDTFQVAIIPYTYEHTNFHTFEIGS
EEEEECHHHHHCCCEEEECCCEEEEEEEEEEECCCCCCEEEEEEEEEEECCCEEEEECCC
VVNIEFDIIGKYISRMIQYK
EEEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]