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The map label for this gene is degQ [C]

Identifier: 29346722

GI number: 29346722

Start: 1635993

End: 1637528

Strand: Reverse

Name: degQ [C]

Synonym: BT_1312

Alternate gene names: 29346722

Gene position: 1637528-1635993 (Counterclockwise)

Preceding gene: 29346723

Following gene: 29346721

Centisome position: 26.16

GC content: 45.12

Gene sequence:

>1536_bases
ATGAAACAGACAACAAAGAACATTCTGGGAGTAGGAGCAATTATTCTTCTGAGCTCAGGAGTTGCAGGATTGACAACTTA
CAAATTGTTGCAATCTAACGAAGCTGCCAAGGAAACATCTTTTAATGAGATGTTCAAGCAGAATCCCAATGTCAAATTGG
CTGCTTTTGATGCGGTAAACGCTCAGCCGGTTGATTTGACACAGGCTGCTGAGAACTCCCTTCATGCTGTTGTACATATA
AGATCTACGCAAGAATCCAAAACTAAAACGATTCAGCAGGCACCGGATATTTTCGATTTCTTCTTCGGTGACGGACGTGG
ACAACAGCGTCAGGTACAAACCCAGCCTCGCGTAGGTTTTGGCTCGGGAGTGATTATCTCTAAAGACGGTTATATCGTAA
CCAACAACCACGTGATTGAAGGTGCAGATGAAATCAGTGTGAAGCTGAATGATAATCGTGAGTTTAAAGGACGTGTAATC
GGTACTGACCCGAGCACTGACCTTGCATTAGTGAAAATAGAAGGAGATGATCTGCCGACTATTCCGGTAGGTGACTCTGA
TGCACTGAAAGTAGGCGAGTGGGTATTGGCAGTAGGTAACCCGTTCAATCTTAACTCTACTGTAACTGCCGGTATCGTCA
GCGCAAAGGCCCGTTCATTGGGTGTATATAATGGTGGTATAGAATCTTTTATCCAGACAGACGCTGCCATTAACCAGGGA
AATAGTGGTGGTGCACTGGTCAATGCTAAGGGAGAACTGGTAGGTATCAACTCTGTACTTTCTTCTCCGACCGGAGCTTA
TGCCGGATATGGATTTGCTATTCCGACCAGCATTATGACGAAGGTTATTGCTGACCTGAAACAATATGGAACTGTGCAGC
GTGCTTTGCTTGGTATCCGTGGAGGATCTATTGGCAGCAGCTTGATGGATGACAGACAACCGATTGATAAGTCCGGTACT
ACTTTGGCAGATAAAGCTAAGGCACTGGGTGTAGTAGAAGGAGTCTGGGTTTCTGAAATTGTTGAAGGTGGCTCGGCTGC
AGGTGCTGATATCAAAGTCGATGACGTAATTATCGGTCTGGATAATAAGAAGGTTTCAAATATGGCCGACTTGCAGGAAG
CTCTTGCTAAACATCGTCCTGGTGATAAGGTGAAAGTAAAACTGATGCGTGATAAGAAGGAAAAGACTGTTGAAGTAACG
TTGAAGAACGAACAAGGCACAACGAAGATTGTAAAAGACGCAGGTATGGACATCCTGGGTGCTGCATTCAAAGAATTGCC
GGATGACTTGAAGAAACAGTTGAACCTCGGTTATGGTCTGCAAGTGACAGGTGTTTCTTCCGGTAAGATGTCAGATGCAG
GAGTCCGCAAAGGCTTCATCATCCTGAAAGCTAATGACCAGCCGATGCGCAAAGTCAGTGATCTGGAAGAAGCAATGAAA
GCTGCTGTTAAGTCTCCGAATCAGGTATTGTTCCTGACAGGTGTATTCCCATCCGGTAAACGCGGATACTTTGCAGTTGA
TCTGACTCAGGAATAA

Upstream 100 bases:

>100_bases
AAGAGTGACAAGTAGAATAAGTGAACGATATTTGTTATTATTTTAACGTCGTAAAAGTTAAAACAATGTCGAATATTAAC
ATTTTAAAGAATTATAAATC

Downstream 100 bases:

>100_bases
ATTATAAATTAAGGTAAGAAGATTGTAGGATAAGCTAATGAAATAGAAAAAGGATGCCGTCACACAACTTGTCGGCATTC
TTTTTTGTTTTATTAGTTGA

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MKQTTKNILGVGAIILLSSGVAGLTTYKLLQSNEAAKETSFNEMFKQNPNVKLAAFDAVNAQPVDLTQAAENSLHAVVHI
RSTQESKTKTIQQAPDIFDFFFGDGRGQQRQVQTQPRVGFGSGVIISKDGYIVTNNHVIEGADEISVKLNDNREFKGRVI
GTDPSTDLALVKIEGDDLPTIPVGDSDALKVGEWVLAVGNPFNLNSTVTAGIVSAKARSLGVYNGGIESFIQTDAAINQG
NSGGALVNAKGELVGINSVLSSPTGAYAGYGFAIPTSIMTKVIADLKQYGTVQRALLGIRGGSIGSSLMDDRQPIDKSGT
TLADKAKALGVVEGVWVSEIVEGGSAAGADIKVDDVIIGLDNKKVSNMADLQEALAKHRPGDKVKVKLMRDKKEKTVEVT
LKNEQGTTKIVKDAGMDILGAAFKELPDDLKKQLNLGYGLQVTGVSSGKMSDAGVRKGFIILKANDQPMRKVSDLEEAMK
AAVKSPNQVLFLTGVFPSGKRGYFAVDLTQE

Sequences:

>Translated_511_residues
MKQTTKNILGVGAIILLSSGVAGLTTYKLLQSNEAAKETSFNEMFKQNPNVKLAAFDAVNAQPVDLTQAAENSLHAVVHI
RSTQESKTKTIQQAPDIFDFFFGDGRGQQRQVQTQPRVGFGSGVIISKDGYIVTNNHVIEGADEISVKLNDNREFKGRVI
GTDPSTDLALVKIEGDDLPTIPVGDSDALKVGEWVLAVGNPFNLNSTVTAGIVSAKARSLGVYNGGIESFIQTDAAINQG
NSGGALVNAKGELVGINSVLSSPTGAYAGYGFAIPTSIMTKVIADLKQYGTVQRALLGIRGGSIGSSLMDDRQPIDKSGT
TLADKAKALGVVEGVWVSEIVEGGSAAGADIKVDDVIIGLDNKKVSNMADLQEALAKHRPGDKVKVKLMRDKKEKTVEVT
LKNEQGTTKIVKDAGMDILGAAFKELPDDLKKQLNLGYGLQVTGVSSGKMSDAGVRKGFIILKANDQPMRKVSDLEEAMK
AAVKSPNQVLFLTGVFPSGKRGYFAVDLTQE
>Mature_511_residues
MKQTTKNILGVGAIILLSSGVAGLTTYKLLQSNEAAKETSFNEMFKQNPNVKLAAFDAVNAQPVDLTQAAENSLHAVVHI
RSTQESKTKTIQQAPDIFDFFFGDGRGQQRQVQTQPRVGFGSGVIISKDGYIVTNNHVIEGADEISVKLNDNREFKGRVI
GTDPSTDLALVKIEGDDLPTIPVGDSDALKVGEWVLAVGNPFNLNSTVTAGIVSAKARSLGVYNGGIESFIQTDAAINQG
NSGGALVNAKGELVGINSVLSSPTGAYAGYGFAIPTSIMTKVIADLKQYGTVQRALLGIRGGSIGSSLMDDRQPIDKSGT
TLADKAKALGVVEGVWVSEIVEGGSAAGADIKVDDVIIGLDNKKVSNMADLQEALAKHRPGDKVKVKLMRDKKEKTVEVT
LKNEQGTTKIVKDAGMDILGAAFKELPDDLKKQLNLGYGLQVTGVSSGKMSDAGVRKGFIILKANDQPMRKVSDLEEAMK
AAVKSPNQVLFLTGVFPSGKRGYFAVDLTQE

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=270, Percent_Identity=34.4444444444444, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI24308541, Length=281, Percent_Identity=33.4519572953737, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI22129776, Length=272, Percent_Identity=33.4558823529412, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI7019477, Length=290, Percent_Identity=33.1034482758621, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1789629, Length=361, Percent_Identity=42.6592797783933, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1786356, Length=436, Percent_Identity=36.697247706422, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789630, Length=292, Percent_Identity=41.4383561643836, Blast_Score=201, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24646839, Length=320, Percent_Identity=30, Blast_Score=132, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 54167; Mature: 54167

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTTKNILGVGAIILLSSGVAGLTTYKLLQSNEAAKETSFNEMFKQNPNVKLAAFDAVN
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCC
AQPVDLTQAAENSLHAVVHIRSTQESKTKTIQQAPDIFDFFFGDGRGQQRQVQTQPRVGF
CCCCCHHHHHCCCEEEEEEEECCCCHHHHHHHHCCCHHHHHHCCCCCCCCHHCCCCCCCC
GSGVIISKDGYIVTNNHVIEGADEISVKLNDNREFKGRVIGTDPSTDLALVKIEGDDLPT
CCCEEEECCCEEEECCEEEECCCEEEEEECCCCCCCCEEECCCCCCCEEEEEECCCCCCC
IPVGDSDALKVGEWVLAVGNPFNLNSTVTAGIVSAKARSLGVYNGGIESFIQTDAAINQG
CCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHHHHCCEECCCHHHHHHHHHHHCCC
NSGGALVNAKGELVGINSVLSSPTGAYAGYGFAIPTSIMTKVIADLKQYGTVQRALLGIR
CCCCEEEECCCCEEEEHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHCHHHHHHHHCC
GGSIGSSLMDDRQPIDKSGTTLADKAKALGVVEGVWVSEIVEGGSAAGADIKVDDVIIGL
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEEEEEC
DNKKVSNMADLQEALAKHRPGDKVKVKLMRDKKEKTVEVTLKNEQGTTKIVKDAGMDILG
CCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHCCCHHHH
AAFKELPDDLKKQLNLGYGLQVTGVSSGKMSDAGVRKGFIILKANDQPMRKVSDLEEAMK
HHHHHCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
AAVKSPNQVLFLTGVFPSGKRGYFAVDLTQE
HHHCCCCEEEEEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure
MKQTTKNILGVGAIILLSSGVAGLTTYKLLQSNEAAKETSFNEMFKQNPNVKLAAFDAVN
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCC
AQPVDLTQAAENSLHAVVHIRSTQESKTKTIQQAPDIFDFFFGDGRGQQRQVQTQPRVGF
CCCCCHHHHHCCCEEEEEEEECCCCHHHHHHHHCCCHHHHHHCCCCCCCCHHCCCCCCCC
GSGVIISKDGYIVTNNHVIEGADEISVKLNDNREFKGRVIGTDPSTDLALVKIEGDDLPT
CCCEEEECCCEEEECCEEEECCCEEEEEECCCCCCCCEEECCCCCCCEEEEEECCCCCCC
IPVGDSDALKVGEWVLAVGNPFNLNSTVTAGIVSAKARSLGVYNGGIESFIQTDAAINQG
CCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHHHHCCEECCCHHHHHHHHHHHCCC
NSGGALVNAKGELVGINSVLSSPTGAYAGYGFAIPTSIMTKVIADLKQYGTVQRALLGIR
CCCCEEEECCCCEEEEHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHCHHHHHHHHCC
GGSIGSSLMDDRQPIDKSGTTLADKAKALGVVEGVWVSEIVEGGSAAGADIKVDDVIIGL
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEEEEEC
DNKKVSNMADLQEALAKHRPGDKVKVKLMRDKKEKTVEVTLKNEQGTTKIVKDAGMDILG
CCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHCCCHHHH
AAFKELPDDLKKQLNLGYGLQVTGVSSGKMSDAGVRKGFIILKANDQPMRKVSDLEEAMK
HHHHHCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
AAVKSPNQVLFLTGVFPSGKRGYFAVDLTQE
HHHCCCCEEEEEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]