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The map label for this gene is sucD [H]

Identifier: 29346197

GI number: 29346197

Start: 976337

End: 977197

Strand: Reverse

Name: sucD [H]

Synonym: BT_0787

Alternate gene names: 29346197

Gene position: 977197-976337 (Counterclockwise)

Preceding gene: 29346198

Following gene: 29346193

Centisome position: 15.61

GC content: 46.46

Gene sequence:

>861_bases
ATGAGTATATTAATAGATAAATCCACCCGTTTGATTGTACAAGGTATTACCGGTAGAGACGGGCTTTTTCATGCCAAGAA
GATGAAAGAATATGGAACGAATGTCGTTGGCGGCACTTCTCCGGGCAAGGGAGGTACGGAAGTAGACGGTATTCCGGTAT
TCAATACGATGCATGAAGCTGTAAAACAGACACAGGCTAATACTTCCATCATCTTTGTGCCGGCCCGTTTTGCAGCAGAT
ACCATTATGGAAGCTGCGGATGCAGGCATCCGGCTAATAGTCTGTATCGCAGAAGGTATTCCGACCCTGGATGTCATCAA
AGCACATCGGTTTGCCGAACAAAGAGGGGCAATGTTGGTTGGCCCCAACTGTCCGGGACTTATTTCTCCCGGAGAAAGTA
TGGTAGGAATCCTTCCGGGACAAGTCTTTCAGAAAGGAAATGTCGGTGTCATCAGCCGTAGTGGAACACTCACTTATGAA
ATAGTATATCACTTAACGACTAATGGTATGGGACAGTCTACTGCAATCGGCATCGGAGGAGATCCTGTGGTAGGTCTGCA
TTTCCTTAAACTACTGGAAATGTTCCAGAATGATCCTGAAACGAAAGCAATTGTGTTAATCGGAGAAATCGGAGGAAACG
CGGAAGAACAGGCTGCTGAATATATTCGCAGTCATGTAAATAAGCCTGTAGTAGCATTTATTGCCGGACAGTCTGCTCCT
CCGGGAAAACAGATGGGCCACGCAGGAGCCATTATCTCGGGAGGTTCCGGCTCGGCAAAAGACAAAATAGAGGCTTTAGA
AGCTGCCGGCATACGAGTTGCACAAGAGCCTTCGGATATTCCTAAGTTACTGAAAAGATAA

Upstream 100 bases:

>100_bases
TACGCAACCATAGCCGTTTTCAGATAGCTACAACTATGCAGGAAGCCGCTTTAATGGCTATCAAATCTTAAGATGAAATC
ACATAAAAAATGAAGGAACA

Downstream 100 bases:

>100_bases
ACAGAACCACACGGAGAAATAGAGCTTTGGGCTTTTGTTTCTCCGTGTGGTTCTATTTTATGTACCAATATATCCCCGCG
ATGATAAAGTAATATCTGAA

Product: succinyl-CoA synthetase alpha chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSILIDKSTRLIVQGITGRDGLFHAKKMKEYGTNVVGGTSPGKGGTEVDGIPVFNTMHEAVKQTQANTSIIFVPARFAAD
TIMEAADAGIRLIVCIAEGIPTLDVIKAHRFAEQRGAMLVGPNCPGLISPGESMVGILPGQVFQKGNVGVISRSGTLTYE
IVYHLTTNGMGQSTAIGIGGDPVVGLHFLKLLEMFQNDPETKAIVLIGEIGGNAEEQAAEYIRSHVNKPVVAFIAGQSAP
PGKQMGHAGAIISGGSGSAKDKIEALEAAGIRVAQEPSDIPKLLKR

Sequences:

>Translated_286_residues
MSILIDKSTRLIVQGITGRDGLFHAKKMKEYGTNVVGGTSPGKGGTEVDGIPVFNTMHEAVKQTQANTSIIFVPARFAAD
TIMEAADAGIRLIVCIAEGIPTLDVIKAHRFAEQRGAMLVGPNCPGLISPGESMVGILPGQVFQKGNVGVISRSGTLTYE
IVYHLTTNGMGQSTAIGIGGDPVVGLHFLKLLEMFQNDPETKAIVLIGEIGGNAEEQAAEYIRSHVNKPVVAFIAGQSAP
PGKQMGHAGAIISGGSGSAKDKIEALEAAGIRVAQEPSDIPKLLKR
>Mature_285_residues
SILIDKSTRLIVQGITGRDGLFHAKKMKEYGTNVVGGTSPGKGGTEVDGIPVFNTMHEAVKQTQANTSIIFVPARFAADT
IMEAADAGIRLIVCIAEGIPTLDVIKAHRFAEQRGAMLVGPNCPGLISPGESMVGILPGQVFQKGNVGVISRSGTLTYEI
VYHLTTNGMGQSTAIGIGGDPVVGLHFLKLLEMFQNDPETKAIVLIGEIGGNAEEQAAEYIRSHVNKPVVAFIAGQSAPP
GKQMGHAGAIISGGSGSAKDKIEALEAAGIRVAQEPSDIPKLLKR

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=283, Percent_Identity=54.416961130742, Blast_Score=265, Evalue=3e-71,
Organism=Homo sapiens, GI38569423, Length=251, Percent_Identity=33.8645418326693, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI38569421, Length=251, Percent_Identity=33.8645418326693, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1786949, Length=285, Percent_Identity=57.5438596491228, Blast_Score=341, Evalue=4e-95,
Organism=Escherichia coli, GI1786513, Length=223, Percent_Identity=24.6636771300448, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17553126, Length=284, Percent_Identity=53.8732394366197, Blast_Score=287, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI17550194, Length=284, Percent_Identity=52.8169014084507, Blast_Score=283, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI17551266, Length=244, Percent_Identity=32.7868852459016, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17557344, Length=274, Percent_Identity=30.6569343065693, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324716, Length=285, Percent_Identity=45.6140350877193, Blast_Score=235, Evalue=7e-63,
Organism=Drosophila melanogaster, GI21356559, Length=284, Percent_Identity=49.2957746478873, Blast_Score=286, Evalue=8e-78,
Organism=Drosophila melanogaster, GI28574296, Length=284, Percent_Identity=52.4647887323944, Blast_Score=263, Evalue=8e-71,
Organism=Drosophila melanogaster, GI281363477, Length=237, Percent_Identity=31.6455696202532, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281363475, Length=237, Percent_Identity=31.6455696202532, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281363473, Length=237, Percent_Identity=31.6455696202532, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29904; Mature: 29773

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIDKSTRLIVQGITGRDGLFHAKKMKEYGTNVVGGTSPGKGGTEVDGIPVFNTMHEA
CEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VKQTQANTSIIFVPARFAADTIMEAADAGIRLIVCIAEGIPTLDVIKAHRFAEQRGAMLV
HHHHCCCCEEEEEEHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEE
GPNCPGLISPGESMVGILPGQVFQKGNVGVISRSGTLTYEIVYHLTTNGMGQSTAIGIGG
CCCCCCCCCCCCCEEEECCHHHCCCCCEEEEECCCCEEEEEEEEEECCCCCCCEEEECCC
DPVVGLHFLKLLEMFQNDPETKAIVLIGEIGGNAEEQAAEYIRSHVNKPVVAFIAGQSAP
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCC
PGKQMGHAGAIISGGSGSAKDKIEALEAAGIRVAQEPSDIPKLLKR
CCHHCCCCCEEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHHHCC
>Mature Secondary Structure 
SILIDKSTRLIVQGITGRDGLFHAKKMKEYGTNVVGGTSPGKGGTEVDGIPVFNTMHEA
EEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VKQTQANTSIIFVPARFAADTIMEAADAGIRLIVCIAEGIPTLDVIKAHRFAEQRGAMLV
HHHHCCCCEEEEEEHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEE
GPNCPGLISPGESMVGILPGQVFQKGNVGVISRSGTLTYEIVYHLTTNGMGQSTAIGIGG
CCCCCCCCCCCCCEEEECCHHHCCCCCEEEEECCCCEEEEEEEEEECCCCCCCEEEECCC
DPVVGLHFLKLLEMFQNDPETKAIVLIGEIGGNAEEQAAEYIRSHVNKPVVAFIAGQSAP
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCC
PGKQMGHAGAIISGGSGSAKDKIEALEAAGIRVAQEPSDIPKLLKR
CCHHCCCCCEEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]