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The map label for this gene is zraR [H]

Identifier: 29346100

GI number: 29346100

Start: 858200

End: 859543

Strand: Reverse

Name: zraR [H]

Synonym: BT_0690

Alternate gene names: 29346100

Gene position: 859543-858200 (Counterclockwise)

Preceding gene: 29346101

Following gene: 29346099

Centisome position: 13.73

GC content: 46.35

Gene sequence:

>1344_bases
ATGAGTAAATCAGGAACCATCATCATTGTAGACGATAATAAAGGGGTGCTGACAGCGGTACAAATCCTTTTAAAAAACTA
CTTTTCGAAAGTCGTCACACTGTCGTCACCGGTCACACTGACCACTGCGATACGAGAGGAAACACCGGAAGTGGTACTAT
TAGATATGAATTTCACTTCGGGCATCAATACCGGCAATGAAGGATTGTTCTGGCTGCACGAAATAAAGAAAGTACGACGG
GAGCTTCCTGTCGTACTTTTTACTGCTTATGCGGATATTGATCTCGCTATCCGGGGAATCAAAGAAGGTGCTTCGGACTT
TATCGTCAAGCCCTGGAATAATCAGAAACTGGTAGAAACACTACAGGCTGCCGCCTCATCCGCACAGCAAGGACGTAAGA
CAGGAAACAAAAAGGAACCGGTCAACACTCCGGCACTCTATTGGGGAGAAAGCAAGTCTATGCAACAACTCCGAACACTG
ATCGAAAAGGTAGCCTCCACAGACGCCAATATCCTGATTACCGGTGAAAACGGAACAGGAAAAGAAATGCTTGCCCGTGA
AATTCACGCTCTTTCCAACCGCAGGCAACAGGAAATGATTGCTGTGGACATGGGAGCAATCACCGAATCTTTATTTGAAA
GCGAACTCTTCGGGCATGTGAAAGGCTCTTTTACCGATGCGCATACCGACCGGACAGGAAAGTTTGAGGCTGCCGATCAC
AGCACATTGTTTCTGGATGAAATAGGAAACCTCCCCTATCACCTGCAAGCCAAACTATTGACGGCTATCCAACGAAGAAG
TATCGTGCGAGTGGGAAGTAACACTCCGATTCCTATTGACATCCGTCTGATATGCGCCACCAACCGGAATTTGCAGGAAA
TGGTAGACCGGGAAGAGTTTCGGGAAGACTTACTCTACCGTATCAACACCATTCATATAGAAATCCCTCCTTTGAGGGAA
CGGAAAGAAGATATTGTCCCTCTTGCCGAAAGATTTATCATCCGCTTCTGCAAGCAATATGATAAGGAACTGATGAAATT
CAGTCCGGCAGCGAAGGAAAAGCTTACCGCACATCCCTGGTACGGCAATATCCGCGAATTGGAGCACGCAATCGAAAAGG
TGGTCATCATTAACGACGGGGTGCAAATCCCTGCGGAATTGTTCCAGTTATCCTCCCGAAAGACAGAAACTTCCGAGAAG
AATATTTCCACCTTGGAAGAGATGGAAGTACAAATGATACGGAAAGCGCTGGATGCTTGTGCAGGAAATCTTTCGGCAGT
AGCTGCGCAACTGGGAATTACCCGACAGACTCTCTATAACAAGATGAAAAAATTCGGATTATGA

Upstream 100 bases:

>100_bases
TATCATTCGGATTAAAGTTCCAATGGCTATAAATTCAAATCCGAATTTTGAATTATGAATTACTTTTTCGTAAGTTTGTA
GCGTACAAACCAATTCGGAC

Downstream 100 bases:

>100_bases
ACCGGATTCTACAACAAGTAGCCAACCAATATTGGTTCAGGGTATCACTGACGGTCATTTGCTGTCTGGCGACTATCTGT
TTGGGCGTGCATCAGTCTTA

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSKSGTIIIVDDNKGVLTAVQILLKNYFSKVVTLSSPVTLTTAIREETPEVVLLDMNFTSGINTGNEGLFWLHEIKKVRR
ELPVVLFTAYADIDLAIRGIKEGASDFIVKPWNNQKLVETLQAAASSAQQGRKTGNKKEPVNTPALYWGESKSMQQLRTL
IEKVASTDANILITGENGTGKEMLAREIHALSNRRQQEMIAVDMGAITESLFESELFGHVKGSFTDAHTDRTGKFEAADH
STLFLDEIGNLPYHLQAKLLTAIQRRSIVRVGSNTPIPIDIRLICATNRNLQEMVDREEFREDLLYRINTIHIEIPPLRE
RKEDIVPLAERFIIRFCKQYDKELMKFSPAAKEKLTAHPWYGNIRELEHAIEKVVIINDGVQIPAELFQLSSRKTETSEK
NISTLEEMEVQMIRKALDACAGNLSAVAAQLGITRQTLYNKMKKFGL

Sequences:

>Translated_447_residues
MSKSGTIIIVDDNKGVLTAVQILLKNYFSKVVTLSSPVTLTTAIREETPEVVLLDMNFTSGINTGNEGLFWLHEIKKVRR
ELPVVLFTAYADIDLAIRGIKEGASDFIVKPWNNQKLVETLQAAASSAQQGRKTGNKKEPVNTPALYWGESKSMQQLRTL
IEKVASTDANILITGENGTGKEMLAREIHALSNRRQQEMIAVDMGAITESLFESELFGHVKGSFTDAHTDRTGKFEAADH
STLFLDEIGNLPYHLQAKLLTAIQRRSIVRVGSNTPIPIDIRLICATNRNLQEMVDREEFREDLLYRINTIHIEIPPLRE
RKEDIVPLAERFIIRFCKQYDKELMKFSPAAKEKLTAHPWYGNIRELEHAIEKVVIINDGVQIPAELFQLSSRKTETSEK
NISTLEEMEVQMIRKALDACAGNLSAVAAQLGITRQTLYNKMKKFGL
>Mature_446_residues
SKSGTIIIVDDNKGVLTAVQILLKNYFSKVVTLSSPVTLTTAIREETPEVVLLDMNFTSGINTGNEGLFWLHEIKKVRRE
LPVVLFTAYADIDLAIRGIKEGASDFIVKPWNNQKLVETLQAAASSAQQGRKTGNKKEPVNTPALYWGESKSMQQLRTLI
EKVASTDANILITGENGTGKEMLAREIHALSNRRQQEMIAVDMGAITESLFESELFGHVKGSFTDAHTDRTGKFEAADHS
TLFLDEIGNLPYHLQAKLLTAIQRRSIVRVGSNTPIPIDIRLICATNRNLQEMVDREEFREDLLYRINTIHIEIPPLRER
KEDIVPLAERFIIRFCKQYDKELMKFSPAAKEKLTAHPWYGNIRELEHAIEKVVIINDGVQIPAELFQLSSRKTETSEKN
ISTLEEMEVQMIRKALDACAGNLSAVAAQLGITRQTLYNKMKKFGL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=443, Percent_Identity=39.0519187358916, Blast_Score=304, Evalue=9e-84,
Organism=Escherichia coli, GI1788550, Length=464, Percent_Identity=36.2068965517241, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI1790299, Length=474, Percent_Identity=33.1223628691983, Blast_Score=268, Evalue=7e-73,
Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=44.1640378548896, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1788905, Length=451, Percent_Identity=32.5942350332594, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI87082117, Length=316, Percent_Identity=39.873417721519, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1789087, Length=304, Percent_Identity=40.4605263157895, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI87082152, Length=314, Percent_Identity=39.8089171974522, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1786524, Length=308, Percent_Identity=36.038961038961, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87081872, Length=313, Percent_Identity=35.4632587859425, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787583, Length=304, Percent_Identity=33.2236842105263, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI87081858, Length=302, Percent_Identity=31.4569536423841, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1789828, Length=233, Percent_Identity=36.480686695279, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50293; Mature: 50161

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSGTIIIVDDNKGVLTAVQILLKNYFSKVVTLSSPVTLTTAIREETPEVVLLDMNFTS
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCEEEEEECCCC
GINTGNEGLFWLHEIKKVRRELPVVLFTAYADIDLAIRGIKEGASDFIVKPWNNQKLVET
CCCCCCCCCHHHHHHHHHHHHCCEEEEEEHHCHHHHHHHHHCCCCCCEECCCCCHHHHHH
LQAAASSAQQGRKTGNKKEPVNTPALYWGESKSMQQLRTLIEKVASTDANILITGENGTG
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
KEMLAREIHALSNRRQQEMIAVDMGAITESLFESELFGHVKGSFTDAHTDRTGKFEAADH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
STLFLDEIGNLPYHLQAKLLTAIQRRSIVRVGSNTPIPIDIRLICATNRNLQEMVDREEF
CEEEHHHHCCCCHHHHHHHHHHHHHHCEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHH
REDLLYRINTIHIEIPPLRERKEDIVPLAERFIIRFCKQYDKELMKFSPAAKEKLTAHPW
HHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
YGNIRELEHAIEKVVIINDGVQIPAELFQLSSRKTETSEKNISTLEEMEVQMIRKALDAC
CCCHHHHHHHHHEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGNLSAVAAQLGITRQTLYNKMKKFGL
CCCHHHHHHHHCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKSGTIIIVDDNKGVLTAVQILLKNYFSKVVTLSSPVTLTTAIREETPEVVLLDMNFTS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCEEEEEECCCC
GINTGNEGLFWLHEIKKVRRELPVVLFTAYADIDLAIRGIKEGASDFIVKPWNNQKLVET
CCCCCCCCCHHHHHHHHHHHHCCEEEEEEHHCHHHHHHHHHCCCCCCEECCCCCHHHHHH
LQAAASSAQQGRKTGNKKEPVNTPALYWGESKSMQQLRTLIEKVASTDANILITGENGTG
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
KEMLAREIHALSNRRQQEMIAVDMGAITESLFESELFGHVKGSFTDAHTDRTGKFEAADH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
STLFLDEIGNLPYHLQAKLLTAIQRRSIVRVGSNTPIPIDIRLICATNRNLQEMVDREEF
CEEEHHHHCCCCHHHHHHHHHHHHHHCEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHH
REDLLYRINTIHIEIPPLRERKEDIVPLAERFIIRFCKQYDKELMKFSPAAKEKLTAHPW
HHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
YGNIRELEHAIEKVVIINDGVQIPAELFQLSSRKTETSEKNISTLEEMEVQMIRKALDAC
CCCHHHHHHHHHEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGNLSAVAAQLGITRQTLYNKMKKFGL
CCCHHHHHHHHCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]