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The map label for this gene is map [C]

Identifier: 29346048

GI number: 29346048

Start: 786540

End: 787463

Strand: Reverse

Name: map [C]

Synonym: BT_0638

Alternate gene names: 29346048

Gene position: 787463-786540 (Counterclockwise)

Preceding gene: 29346049

Following gene: 29346047

Centisome position: 12.58

GC content: 44.05

Gene sequence:

>924_bases
ATGATAAACGATTTCATTTTCCATTTATTCTCGTACCTTTGTAGTACGATTAAAAAACATCCTATAATAATGAAGAACTT
TATCAAGGGATTCCGGTTTACTCCCTCCAATTACCCGGCTGAAGTAGAAGCGAAAATACAGAAATACAGAAAACAAGGTT
ACAAACTCCCACCGCGCAAAGTACTGCGTACTCCCGAACAACTGGAAGGAATCCGTGAGAGTGCCAAAATCAATACTGCC
CTGTTGGATTATATTTCGGAGAATATCCGTGAAGGAATGTCGACTGAAGAAATCGATGTCATGGTATATGACTTCACCAC
AAAGCACGGTGCCATCCCTGCTCCTCTCAACTACGAAGGATTTCCTAAAAGCGTCTGCACCAGTATCAATGATGTGGTAT
GCCACGGTATTCCCAGCAAAACAGAAATACTGCAAAGCGGAGATATCATCAATGTAGATGTTTCTACCATTTACAAAGGA
TATTTCTCCGACGCATCCCGTATGTTTATGATCGGTGACGTAAGTCCCGAAATGCGCAAACTGGTTCAAGTGACTAAAGA
GTGTATGGAAATAGGTATAGCCGCCGCACAGCCTTGGAAACAATTAGGAGATGTAGGCGCCGCTATTCAGGAACACGCAG
AAAAGAACGGATTCAACGTGGTACGCGATCTTTGCGGGCATGGTGTAGGAATGCAGTTTCATGAAGCACCGGATGTGGAA
CATTTCGGACGCCGGGGAACAGGAATGATGATCGTTCCGGGCATGACCTTCACCATTGAACCGATGATAAATATGGGTAC
TTATGAAGTATTTGTTGACGAAGCTGACGGATGGACGGTATGCACGGATGACGGACTGCCTTCTGCCCAATGGGAGAATA
TGATTCTGATTACTGAAACCGGAAACGAAATTCTGACTTATTGA

Upstream 100 bases:

>100_bases
ATTGAAAACCGGCGTACAATATCAATACAACACCATACAAAAAAGATGGGAATGGGTGCCTCAGATCTGTATTTCTTATG
AATGGTAAAAAAGGAATCAC

Downstream 100 bases:

>100_bases
TGGAACTGATTCTACTTATTGTTATTGCCGCATTAGCAGTAATCTCGATTGTACTATCACTGGCAAAAGGAAATAATCAT
GCGCAAGCGGAACAATTACA

Product: putative methionine aminopeptidase A

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MINDFIFHLFSYLCSTIKKHPIIMKNFIKGFRFTPSNYPAEVEAKIQKYRKQGYKLPPRKVLRTPEQLEGIRESAKINTA
LLDYISENIREGMSTEEIDVMVYDFTTKHGAIPAPLNYEGFPKSVCTSINDVVCHGIPSKTEILQSGDIINVDVSTIYKG
YFSDASRMFMIGDVSPEMRKLVQVTKECMEIGIAAAQPWKQLGDVGAAIQEHAEKNGFNVVRDLCGHGVGMQFHEAPDVE
HFGRRGTGMMIVPGMTFTIEPMINMGTYEVFVDEADGWTVCTDDGLPSAQWENMILITETGNEILTY

Sequences:

>Translated_307_residues
MINDFIFHLFSYLCSTIKKHPIIMKNFIKGFRFTPSNYPAEVEAKIQKYRKQGYKLPPRKVLRTPEQLEGIRESAKINTA
LLDYISENIREGMSTEEIDVMVYDFTTKHGAIPAPLNYEGFPKSVCTSINDVVCHGIPSKTEILQSGDIINVDVSTIYKG
YFSDASRMFMIGDVSPEMRKLVQVTKECMEIGIAAAQPWKQLGDVGAAIQEHAEKNGFNVVRDLCGHGVGMQFHEAPDVE
HFGRRGTGMMIVPGMTFTIEPMINMGTYEVFVDEADGWTVCTDDGLPSAQWENMILITETGNEILTY
>Mature_307_residues
MINDFIFHLFSYLCSTIKKHPIIMKNFIKGFRFTPSNYPAEVEAKIQKYRKQGYKLPPRKVLRTPEQLEGIRESAKINTA
LLDYISENIREGMSTEEIDVMVYDFTTKHGAIPAPLNYEGFPKSVCTSINDVVCHGIPSKTEILQSGDIINVDVSTIYKG
YFSDASRMFMIGDVSPEMRKLVQVTKECMEIGIAAAQPWKQLGDVGAAIQEHAEKNGFNVVRDLCGHGVGMQFHEAPDVE
HFGRRGTGMMIVPGMTFTIEPMINMGTYEVFVDEADGWTVCTDDGLPSAQWENMILITETGNEILTY

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=247, Percent_Identity=44.5344129554656, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI40385867, Length=245, Percent_Identity=40.4081632653061, Blast_Score=192, Evalue=4e-49,
Organism=Escherichia coli, GI1786364, Length=246, Percent_Identity=43.4959349593496, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI1788728, Length=252, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789275, Length=270, Percent_Identity=22.5925925925926, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=250, Percent_Identity=44, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6323273, Length=242, Percent_Identity=42.9752066115703, Blast_Score=220, Evalue=2e-58,
Organism=Drosophila melanogaster, GI21355531, Length=241, Percent_Identity=41.49377593361, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24583427, Length=256, Percent_Identity=39.0625, Blast_Score=191, Evalue=6e-49,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 34500; Mature: 34500

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDFIFHLFSYLCSTIKKHPIIMKNFIKGFRFTPSNYPAEVEAKIQKYRKQGYKLPPRK
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHH
VLRTPEQLEGIRESAKINTALLDYISENIREGMSTEEIDVMVYDFTTKHGAIPAPLNYEG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCC
FPKSVCTSINDVVCHGIPSKTEILQSGDIINVDVSTIYKGYFSDASRMFMIGDVSPEMRK
CCHHHHHHHHHHHHCCCCCHHHHHHCCCEEEEEHHHHHHHHHCCCCCEEEEECCCHHHHH
LVQVTKECMEIGIAAAQPWKQLGDVGAAIQEHAEKNGFNVVRDLCGHGVGMQFHEAPDVE
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHH
HFGRRGTGMMIVPGMTFTIEPMINMGTYEVFVDEADGWTVCTDDGLPSAQWENMILITET
HHCCCCCCEEEECCCEEEECCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEEC
GNEILTY
CCCCCCC
>Mature Secondary Structure
MINDFIFHLFSYLCSTIKKHPIIMKNFIKGFRFTPSNYPAEVEAKIQKYRKQGYKLPPRK
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHH
VLRTPEQLEGIRESAKINTALLDYISENIREGMSTEEIDVMVYDFTTKHGAIPAPLNYEG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCC
FPKSVCTSINDVVCHGIPSKTEILQSGDIINVDVSTIYKGYFSDASRMFMIGDVSPEMRK
CCHHHHHHHHHHHHCCCCCHHHHHHCCCEEEEEHHHHHHHHHCCCCCEEEEECCCHHHHH
LVQVTKECMEIGIAAAQPWKQLGDVGAAIQEHAEKNGFNVVRDLCGHGVGMQFHEAPDVE
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHH
HFGRRGTGMMIVPGMTFTIEPMINMGTYEVFVDEADGWTVCTDDGLPSAQWENMILITET
HHCCCCCCEEEECCCEEEECCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEEC
GNEILTY
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]