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The map label for this gene is dapL [H]

Identifier: 29345957

GI number: 29345957

Start: 673080

End: 674312

Strand: Reverse

Name: dapL [H]

Synonym: BT_0547

Alternate gene names: 29345957

Gene position: 674312-673080 (Counterclockwise)

Preceding gene: 29345958

Following gene: 29345956

Centisome position: 10.77

GC content: 45.99

Gene sequence:

>1233_bases
ATGGCATTAGTAAACGAACATTTTTTGAAATTACCGGGGAGCTATTTGTTCTCGGATATAGCGAAGAAGGTAAATACATT
CAAAATAACGCATCCGAAGCAGGATATTATTCGGTTAGGTATCGGAGATGTCACTCAGCCGCTTCCCAAAGCATGTATCG
AGGCTATGCACAAAGCAGTGGAAGAGCTGGCAAGTAAAGATACATTTCGCGGATATGGTCCTGAGCAGGGGTACGATTTT
TTGATTGAAGCTATTATAAAGAATGATTTCGCTCCACGTGGCATTCATTTCTCACCATCAGAAATATTCGTCAACGACGG
AGCCAAAAGTGATACCGGAAATATCGGCGATATCCTTCGCCACGACAATAGTGTCGGTGTAACAGACCCTATTTACCCGG
TATATATTGACAGTAACGTCATGTGCGGACGTGCCGGAGTGCTGGAAGAAGGAACAGGCAAATGGAGCAATGTGACTTAT
ATGCCTTGTACAAGTGAGAATGACTTCATTCCGGAGATTCCCGACAAACGGATAGACATTGTTTACCTCTGCTACCCGAA
CAATCCGACAGGGACGACACTGACCAAACCGGAACTAAAAAAGTGGGTAGACTATGCATTGGCAAATGATACACTGATTT
TGTTCGATGCCGCATACGAAGCCTATATTCAGGATGCGGATGTCCCCCACTCCATATACGAAATCAAAGGAGCCAAGAAA
TGTGCTATTGAGTTCCGCAGTTTCTCAAAGACAGCCGGTTTCACCGGAGTACGTTGCGGATATACCGTAGTCCCGAAAGA
ACTGACAGCTGCCACACTGGAAGGCGACCGGATTCCACTCAACAAATTATGGAACCGCCGCCAGTGCACTAAATTCAACG
GCACTTCGTACATCACACAACGTGCAGCGGAAGCCGTCTACAGTACAGAAGGCAAAGCACAGATTAAAGAAACGATTAAC
TATTATATGAGCAATGCGAAGATCATGAAGGAAGGACTGGAAGCTACCGGATTGAAAGTATACGGAGGCGTCAATGCTCC
ATACTTATGGGTGAAAACCCCGAACGGGCTCTCTTCCTGGCGATTCTTCGAACAGATGTTGTATGAAGCCAATGTAGTAG
GAACCCCCGGTGTAGGTTTCGGCCCCAGCGGTGAGGGATATATCCGACTGACAGCATTCGGCGATCACAATGATTGTATG
GAAGCAATGAGAAGAATAAAGAACTGGCTTTGA

Upstream 100 bases:

>100_bases
AGGACCGGCAACTAAAGTTTTTGATGGGGAGATGGAGGGATAGGTAATAAGTATTAGGTAATAGGTAACAGGTTTTGCAG
AAACTTAAAACAATAACAAT

Downstream 100 bases:

>100_bases
TAGTATTTTGCGCGCTACTATATAACACTGGACCGTACATCCACATTTTTCTAACTATTAAAGGTAAAAAGACGATGAAA
ACGACGATTAACAAAAAATT

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MALVNEHFLKLPGSYLFSDIAKKVNTFKITHPKQDIIRLGIGDVTQPLPKACIEAMHKAVEELASKDTFRGYGPEQGYDF
LIEAIIKNDFAPRGIHFSPSEIFVNDGAKSDTGNIGDILRHDNSVGVTDPIYPVYIDSNVMCGRAGVLEEGTGKWSNVTY
MPCTSENDFIPEIPDKRIDIVYLCYPNNPTGTTLTKPELKKWVDYALANDTLILFDAAYEAYIQDADVPHSIYEIKGAKK
CAIEFRSFSKTAGFTGVRCGYTVVPKELTAATLEGDRIPLNKLWNRRQCTKFNGTSYITQRAAEAVYSTEGKAQIKETIN
YYMSNAKIMKEGLEATGLKVYGGVNAPYLWVKTPNGLSSWRFFEQMLYEANVVGTPGVGFGPSGEGYIRLTAFGDHNDCM
EAMRRIKNWL

Sequences:

>Translated_410_residues
MALVNEHFLKLPGSYLFSDIAKKVNTFKITHPKQDIIRLGIGDVTQPLPKACIEAMHKAVEELASKDTFRGYGPEQGYDF
LIEAIIKNDFAPRGIHFSPSEIFVNDGAKSDTGNIGDILRHDNSVGVTDPIYPVYIDSNVMCGRAGVLEEGTGKWSNVTY
MPCTSENDFIPEIPDKRIDIVYLCYPNNPTGTTLTKPELKKWVDYALANDTLILFDAAYEAYIQDADVPHSIYEIKGAKK
CAIEFRSFSKTAGFTGVRCGYTVVPKELTAATLEGDRIPLNKLWNRRQCTKFNGTSYITQRAAEAVYSTEGKAQIKETIN
YYMSNAKIMKEGLEATGLKVYGGVNAPYLWVKTPNGLSSWRFFEQMLYEANVVGTPGVGFGPSGEGYIRLTAFGDHNDCM
EAMRRIKNWL
>Mature_409_residues
ALVNEHFLKLPGSYLFSDIAKKVNTFKITHPKQDIIRLGIGDVTQPLPKACIEAMHKAVEELASKDTFRGYGPEQGYDFL
IEAIIKNDFAPRGIHFSPSEIFVNDGAKSDTGNIGDILRHDNSVGVTDPIYPVYIDSNVMCGRAGVLEEGTGKWSNVTYM
PCTSENDFIPEIPDKRIDIVYLCYPNNPTGTTLTKPELKKWVDYALANDTLILFDAAYEAYIQDADVPHSIYEIKGAKKC
AIEFRSFSKTAGFTGVRCGYTVVPKELTAATLEGDRIPLNKLWNRRQCTKFNGTSYITQRAAEAVYSTEGKAQIKETINY
YMSNAKIMKEGLEATGLKVYGGVNAPYLWVKTPNGLSSWRFFEQMLYEANVVGTPGVGFGPSGEGYIRLTAFGDHNDCME
AMRRIKNWL

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=24.6113989637306, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 45697; Mature: 45566

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVNEHFLKLPGSYLFSDIAKKVNTFKITHPKQDIIRLGIGDVTQPLPKACIEAMHKAV
CCCCCCHHHHCCHHHHHHHHHHHHCEEEEECCHHHHHEECCCHHCHHHHHHHHHHHHHHH
EELASKDTFRGYGPEQGYDFLIEAIIKNDFAPRGIHFSPSEIFVNDGAKSDTGNIGDILR
HHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHH
HDNSVGVTDPIYPVYIDSNVMCGRAGVLEEGTGKWSNVTYMPCTSENDFIPEIPDKRIDI
CCCCCCCCCCCEEEEECCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEE
VYLCYPNNPTGTTLTKPELKKWVDYALANDTLILFDAAYEAYIQDADVPHSIYEIKGAKK
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHCCCCCCHHHHHHCCCHH
CAIEFRSFSKTAGFTGVRCGYTVVPKELTAATLEGDRIPLNKLWNRRQCTKFNGTSYITQ
HHHHHHHHHCCCCCCCCCCCCEECCHHHHHEECCCCCCCHHHHCCCCCCCCCCCCHHHHH
RAAEAVYSTEGKAQIKETINYYMSNAKIMKEGLEATGLKVYGGVNAPYLWVKTPNGLSSW
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCHHH
RFFEQMLYEANVVGTPGVGFGPSGEGYIRLTAFGDHNDCMEAMRRIKNWL
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALVNEHFLKLPGSYLFSDIAKKVNTFKITHPKQDIIRLGIGDVTQPLPKACIEAMHKAV
CCCCCHHHHCCHHHHHHHHHHHHCEEEEECCHHHHHEECCCHHCHHHHHHHHHHHHHHH
EELASKDTFRGYGPEQGYDFLIEAIIKNDFAPRGIHFSPSEIFVNDGAKSDTGNIGDILR
HHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHH
HDNSVGVTDPIYPVYIDSNVMCGRAGVLEEGTGKWSNVTYMPCTSENDFIPEIPDKRIDI
CCCCCCCCCCCEEEEECCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEE
VYLCYPNNPTGTTLTKPELKKWVDYALANDTLILFDAAYEAYIQDADVPHSIYEIKGAKK
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHCCCCCCHHHHHHCCCHH
CAIEFRSFSKTAGFTGVRCGYTVVPKELTAATLEGDRIPLNKLWNRRQCTKFNGTSYITQ
HHHHHHHHHCCCCCCCCCCCCEECCHHHHHEECCCCCCCHHHHCCCCCCCCCCCCHHHHH
RAAEAVYSTEGKAQIKETINYYMSNAKIMKEGLEATGLKVYGGVNAPYLWVKTPNGLSSW
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCHHH
RFFEQMLYEANVVGTPGVGFGPSGEGYIRLTAFGDHNDCMEAMRRIKNWL
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA