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The map label for this gene is trpD

Identifier: 29345940

GI number: 29345940

Start: 653313

End: 654311

Strand: Reverse

Name: trpD

Synonym: BT_0530

Alternate gene names: 29345940

Gene position: 654311-653313 (Counterclockwise)

Preceding gene: 29345941

Following gene: 29345939

Centisome position: 10.45

GC content: 43.54

Gene sequence:

>999_bases
ATGAAACAGATTCTATATAAACTTTTCGAACACCAATATTTGGGACGCGATGAAGCACGTACTATCCTGCAAAACATCGC
ACAAGGGAAATATAATGACGTACAGGTAGCATCACTGATTACTGTCTTTCTGATGCGTAATATTTCTGTCGAAGAATTAT
GCGGATTCCGTGATGCATTATTGGAAATGCGGGTTCCGGTTGATTTGAGCGAGTTTGCTCCGATCGATATTGTCGGTACG
GGAGGAGATGGAAAAAATACGTTCAACATTTCTACGGCGGCCTGCTTTACAGTAGCCGGAGCAGGTATTCCGGTAGTAAA
ACATGGCAATTATGGAGCTACTTCAGTCAGCGGTGCCAGCAATGTGATGGAGCAACATGGGGTTAAATTCACAAGTGATG
TTGATCAGATGCGGCGCAGCATGGAACAATGTAATATTGCTTATCTGCACGCTCCTTTGTTCAATCCGGCACTGAAGGCA
GTTGCCCCGATCCGTAAAGGATTGGCGGTACGTACATTCTTTAATATGCTCGGTCCGTTGGTCAATCCGGTGTTGCCGAC
TTATCAGCTTTTAGGCGTGTATAATCTTCCACTTTTGCGCCTTTATACCTATACTTATCAGGAGAGTAAGACTAAATTTG
CCGTTGTACATAGCCTGGACGGATATGATGAGATTTCTCTGACGAACGAGTTTAAGGTAGCTACCTGTGGCAATGAGAAG
ATTTATACTCCGGAAGGTCTCGGATTTGCACGTTATCAGGATACTGATCTGGATGGTGGACAGACACCGGAAGATGCTGC
TAAAATCTTTGATAACATCATGAACAATACAGCTACGGAAGCACAGAAAAACGTGGTTGTTATCAATGCAGCTTTCGCTA
TTCAAGTAGTTCGTCCGGAAAAAACGATTGAAGAGTGCATCGCCCTCGCTAAAGAATCACTAGAAAGTGGCCGGGCATTG
GCTACACTGAAGAAATTCATTGAATTGAATAATAAGTAA

Upstream 100 bases:

>100_bases
CACAAAACCTATGATGTACATGGCATCCAGTTCCATCCCGAATCCGTACTGACTCCGCAAGGAAAAGAAATCATCAAAAA
CTTCTTAAACGAATAAACTT

Downstream 100 bases:

>100_bases
TAGGTAATAAGTTATAAATGATAAGTGGTAAAGGATGAATATGCGATATCCTTTGCCTTGATTCTAAATTTAAGATTAAT
GAAAGATATATTATCCGAAA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKQILYKLFEHQYLGRDEARTILQNIAQGKYNDVQVASLITVFLMRNISVEELCGFRDALLEMRVPVDLSEFAPIDIVGT
GGDGKNTFNISTAACFTVAGAGIPVVKHGNYGATSVSGASNVMEQHGVKFTSDVDQMRRSMEQCNIAYLHAPLFNPALKA
VAPIRKGLAVRTFFNMLGPLVNPVLPTYQLLGVYNLPLLRLYTYTYQESKTKFAVVHSLDGYDEISLTNEFKVATCGNEK
IYTPEGLGFARYQDTDLDGGQTPEDAAKIFDNIMNNTATEAQKNVVVINAAFAIQVVRPEKTIEECIALAKESLESGRAL
ATLKKFIELNNK

Sequences:

>Translated_332_residues
MKQILYKLFEHQYLGRDEARTILQNIAQGKYNDVQVASLITVFLMRNISVEELCGFRDALLEMRVPVDLSEFAPIDIVGT
GGDGKNTFNISTAACFTVAGAGIPVVKHGNYGATSVSGASNVMEQHGVKFTSDVDQMRRSMEQCNIAYLHAPLFNPALKA
VAPIRKGLAVRTFFNMLGPLVNPVLPTYQLLGVYNLPLLRLYTYTYQESKTKFAVVHSLDGYDEISLTNEFKVATCGNEK
IYTPEGLGFARYQDTDLDGGQTPEDAAKIFDNIMNNTATEAQKNVVVINAAFAIQVVRPEKTIEECIALAKESLESGRAL
ATLKKFIELNNK
>Mature_332_residues
MKQILYKLFEHQYLGRDEARTILQNIAQGKYNDVQVASLITVFLMRNISVEELCGFRDALLEMRVPVDLSEFAPIDIVGT
GGDGKNTFNISTAACFTVAGAGIPVVKHGNYGATSVSGASNVMEQHGVKFTSDVDQMRRSMEQCNIAYLHAPLFNPALKA
VAPIRKGLAVRTFFNMLGPLVNPVLPTYQLLGVYNLPLLRLYTYTYQESKTKFAVVHSLDGYDEISLTNEFKVATCGNEK
IYTPEGLGFARYQDTDLDGGQTPEDAAKIFDNIMNNTATEAQKNVVVINAAFAIQVVRPEKTIEECIALAKESLESGRAL
ATLKKFIELNNK

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=34.6289752650177, Blast_Score=154, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6320561, Length=271, Percent_Identity=30.2583025830258, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_BACTN (Q8AAD5)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_809443.1
- HSSP:   Q8YXQ9
- ProteinModelPortal:   Q8AAD5
- GeneID:   1071982
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_0530
- NMPDR:   fig|226186.1.peg.530
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q8AAD5
- ProtClustDB:   CLSK913502
- BioCyc:   BTHE226186:BT_0530-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36621; Mature: 36621

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQILYKLFEHQYLGRDEARTILQNIAQGKYNDVQVASLITVFLMRNISVEELCGFRDAL
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHCHHHHH
LEMRVPVDLSEFAPIDIVGTGGDGKNTFNISTAACFTVAGAGIPVVKHGNYGATSVSGAS
HHHCCCCCHHHCCCEEEEECCCCCCCEEEEHHHHHHHHHCCCCCEEECCCCCCCCCCHHH
NVMEQHGVKFTSDVDQMRRSMEQCNIAYLHAPLFNPALKAVAPIRKGLAVRTFFNMLGPL
HHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VNPVLPTYQLLGVYNLPLLRLYTYTYQESKTKFAVVHSLDGYDEISLTNEFKVATCGNEK
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCCEEEEECCCCE
IYTPEGLGFARYQDTDLDGGQTPEDAAKIFDNIMNNTATEAQKNVVVINAAFAIQVVRPE
EECCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCEEEEEEEEEEEEECCH
KTIEECIALAKESLESGRALATLKKFIELNNK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQILYKLFEHQYLGRDEARTILQNIAQGKYNDVQVASLITVFLMRNISVEELCGFRDAL
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHCHHHHH
LEMRVPVDLSEFAPIDIVGTGGDGKNTFNISTAACFTVAGAGIPVVKHGNYGATSVSGAS
HHHCCCCCHHHCCCEEEEECCCCCCCEEEEHHHHHHHHHCCCCCEEECCCCCCCCCCHHH
NVMEQHGVKFTSDVDQMRRSMEQCNIAYLHAPLFNPALKAVAPIRKGLAVRTFFNMLGPL
HHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VNPVLPTYQLLGVYNLPLLRLYTYTYQESKTKFAVVHSLDGYDEISLTNEFKVATCGNEK
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCCEEEEECCCCE
IYTPEGLGFARYQDTDLDGGQTPEDAAKIFDNIMNNTATEAQKNVVVINAAFAIQVVRPE
EECCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCEEEEEEEEEEEEECCH
KTIEECIALAKESLESGRALATLKKFIELNNK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928