Click here to switch to the map view.

The map label for this gene is sglT [H]

Identifier: 29345765

GI number: 29345765

Start: 427031

End: 428725

Strand: Reverse

Name: sglT [H]

Synonym: BT_0355

Alternate gene names: 29345765

Gene position: 428725-427031 (Counterclockwise)

Preceding gene: 29345766

Following gene: 29345764

Centisome position: 6.85

GC content: 48.14

Gene sequence:

>1695_bases
GTGGAAGCATTAGATTGGCTAGTAATTGGAGTCTTCTTTTTGGCTCTGATAGGTATTATTGTTTGGGTAGTCAGACAAAA
ACAAAATGACTCGGCAGATTATTTCTTAGGCGGACGTGACGCAACATGGCTTGCGATCGGTGCCTCTATCTTCGCATCAA
ACATCGGCTCGGAACACTTGATCGGACTGGCGGGAGCAGGAGCTTCAAGCGGTATGGCGATGGCTCACTGGGAAATTCAG
GGATGGATGATCCTGATTCTGGGATGGGTATTCGTACCTTTCTATTCACGAAGCATGGTATACACGATGCCGGAATTTCT
GGAACGCCGTTACAATCCTCAGTCACGTACCATCTTATCGGTCATCTCACTGGTAAGTTATGTATTGACCAAGGTAGCAG
TGACAGTATATGCCGGCGGACTGGTATTCCAGCAAGTATTCGGCATCAAGGAACTCTGGGGAATCGACTTCTTCTGGATT
GCCGCCATCGGACTGGTTGTTCTCACTGCACTATATACGATCTTCGGTGGTATGAAATCGGTACTTTATACTTCTGTACT
TCAGACTCCGATTCTTCTGTTAGGCTCGTTGATTATCCTTGTGCTCGGTTTCAAAGAACTGGGAGGCTGGGACGAAATGA
TGAGAGTGTGCGGTGCTGTGACGGTAAACGATTATGGTGACACCATGACCAATCTGATCCGCAGCAACGATGATGCGAAC
TTCCCTTGGCTGGGTGCACTTATCGGTTCTGCCATTATCGGTTTCTGGTACTGGTGTACTGACCAGTTCATCGTACAACG
TGTACTTTCCGGAAAGAATGAAAAAGAGGCTCGTCGCGGTACTATCTTCGGCGCTTACCTGAAGCTGTTGCCTGTATTCC
TGTTCCTGATTCCGGGTATGATTGCTTTCGCATTACATCAGAAATATATCGGTGCCGGTGGCGAAGGTTTCCTCCCAATG
CTTGCCAATGGTACTGCCAACGCTGACGCCGCCTTCCCTACTCTGGTAGCTAAATTGCTTCCTGCCGGTGTGAAAGGTCT
GGTAGTATGCGGTATCCTCGCTGCCTTGATGAGTTCGCTGGCTTCACTGTTCAACTCATCTGCCATGTTGTTTACAATCG
ATTTCTACAAACGCTTCCGTCCGGAGACTCCGGAAAAGAAACTGGTGGGTATTGGTCAGATAGCAACTGTAGTGATCGTA
ATCCTCGGTATTCTCTGGATTCCTATCATGCGTAGCGTAGGTGATGTACTTTATACTTATTTGCAGGACGTTCAGTCTGT
ATTGGCTCCGGGTATTGCCGCTGCCTTCCTGCTGGGTATCTGCTGGAAACGTACTTCCGCACAAGGTGGTATGTGGGGAT
TGATCGCCGGTATGATCATCGGTCTGACTCGTCTGGGTGCCAAAGTATATTACAGCAACGCAGGTGAAGTGGCAGATTCT
ACCTTCAAATATTTGTTCTACGATATGAACTGGCTGTTCTTCTGCGGATGGATGTTCCTGTTCTGTATCATCGTAGTCAT
CGTAGTCAGCCTTGCCACGGAAGCTCCGACAGCTGAAAAGATTCAGGGACTGGTATTCGGTACGGCAACGAAAGAACAAA
AAGCGGCTACCCGCGCAAGCTGGGATCACTGGGATATCATTCATACAGTAATCATCCTTGCTATCACAGGTGCCTTCTAC
TGGTATTTCTGGTAA

Upstream 100 bases:

>100_bases
TGGCCGTCCGTTGTGCTGGAACCGGGACAAACGTACAACAGCGAATGTATCTTTAAATTCTCGACAGAGAAATAATATTA
ACTTATAAATCAAATTTATT

Downstream 100 bases:

>100_bases
TTAAATAAATTCATTCAAACGATGAAAAACTATTATAGTTCGAATCCTACCTTCTATCTCGGTATCGACTGCATCATCTT
CGGTTTTAATGAAGGCGAAA

Product: Na+/glucose cotransporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MEALDWLVIGVFFLALIGIIVWVVRQKQNDSADYFLGGRDATWLAIGASIFASNIGSEHLIGLAGAGASSGMAMAHWEIQ
GWMILILGWVFVPFYSRSMVYTMPEFLERRYNPQSRTILSVISLVSYVLTKVAVTVYAGGLVFQQVFGIKELWGIDFFWI
AAIGLVVLTALYTIFGGMKSVLYTSVLQTPILLLGSLIILVLGFKELGGWDEMMRVCGAVTVNDYGDTMTNLIRSNDDAN
FPWLGALIGSAIIGFWYWCTDQFIVQRVLSGKNEKEARRGTIFGAYLKLLPVFLFLIPGMIAFALHQKYIGAGGEGFLPM
LANGTANADAAFPTLVAKLLPAGVKGLVVCGILAALMSSLASLFNSSAMLFTIDFYKRFRPETPEKKLVGIGQIATVVIV
ILGILWIPIMRSVGDVLYTYLQDVQSVLAPGIAAAFLLGICWKRTSAQGGMWGLIAGMIIGLTRLGAKVYYSNAGEVADS
TFKYLFYDMNWLFFCGWMFLFCIIVVIVVSLATEAPTAEKIQGLVFGTATKEQKAATRASWDHWDIIHTVIILAITGAFY
WYFW

Sequences:

>Translated_564_residues
MEALDWLVIGVFFLALIGIIVWVVRQKQNDSADYFLGGRDATWLAIGASIFASNIGSEHLIGLAGAGASSGMAMAHWEIQ
GWMILILGWVFVPFYSRSMVYTMPEFLERRYNPQSRTILSVISLVSYVLTKVAVTVYAGGLVFQQVFGIKELWGIDFFWI
AAIGLVVLTALYTIFGGMKSVLYTSVLQTPILLLGSLIILVLGFKELGGWDEMMRVCGAVTVNDYGDTMTNLIRSNDDAN
FPWLGALIGSAIIGFWYWCTDQFIVQRVLSGKNEKEARRGTIFGAYLKLLPVFLFLIPGMIAFALHQKYIGAGGEGFLPM
LANGTANADAAFPTLVAKLLPAGVKGLVVCGILAALMSSLASLFNSSAMLFTIDFYKRFRPETPEKKLVGIGQIATVVIV
ILGILWIPIMRSVGDVLYTYLQDVQSVLAPGIAAAFLLGICWKRTSAQGGMWGLIAGMIIGLTRLGAKVYYSNAGEVADS
TFKYLFYDMNWLFFCGWMFLFCIIVVIVVSLATEAPTAEKIQGLVFGTATKEQKAATRASWDHWDIIHTVIILAITGAFY
WYFW
>Mature_564_residues
MEALDWLVIGVFFLALIGIIVWVVRQKQNDSADYFLGGRDATWLAIGASIFASNIGSEHLIGLAGAGASSGMAMAHWEIQ
GWMILILGWVFVPFYSRSMVYTMPEFLERRYNPQSRTILSVISLVSYVLTKVAVTVYAGGLVFQQVFGIKELWGIDFFWI
AAIGLVVLTALYTIFGGMKSVLYTSVLQTPILLLGSLIILVLGFKELGGWDEMMRVCGAVTVNDYGDTMTNLIRSNDDAN
FPWLGALIGSAIIGFWYWCTDQFIVQRVLSGKNEKEARRGTIFGAYLKLLPVFLFLIPGMIAFALHQKYIGAGGEGFLPM
LANGTANADAAFPTLVAKLLPAGVKGLVVCGILAALMSSLASLFNSSAMLFTIDFYKRFRPETPEKKLVGIGQIATVVIV
ILGILWIPIMRSVGDVLYTYLQDVQSVLAPGIAAAFLLGICWKRTSAQGGMWGLIAGMIIGLTRLGAKVYYSNAGEVADS
TFKYLFYDMNWLFFCGWMFLFCIIVVIVVSLATEAPTAEKIQGLVFGTATKEQKAATRASWDHWDIIHTVIILAITGAFY
WYFW

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI110835708, Length=590, Percent_Identity=33.8983050847458, Blast_Score=341, Evalue=1e-93,
Organism=Homo sapiens, GI14140236, Length=536, Percent_Identity=35.8208955223881, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI17941285, Length=552, Percent_Identity=36.4130434782609, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI4507033, Length=553, Percent_Identity=36.3471971066908, Blast_Score=320, Evalue=3e-87,
Organism=Homo sapiens, GI109659836, Length=583, Percent_Identity=35.8490566037736, Blast_Score=319, Evalue=5e-87,
Organism=Homo sapiens, GI109659839, Length=599, Percent_Identity=35.0584307178631, Blast_Score=314, Evalue=1e-85,
Organism=Homo sapiens, GI4507031, Length=535, Percent_Identity=36.2616822429907, Blast_Score=312, Evalue=5e-85,
Organism=Homo sapiens, GI206597483, Length=518, Percent_Identity=37.4517374517375, Blast_Score=310, Evalue=3e-84,
Organism=Homo sapiens, GI206597487, Length=543, Percent_Identity=35.5432780847145, Blast_Score=302, Evalue=6e-82,
Organism=Homo sapiens, GI157671931, Length=561, Percent_Identity=23.5294117647059, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI4507035, Length=395, Percent_Identity=23.5443037974684, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI256985183, Length=382, Percent_Identity=23.5602094240838, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI167466278, Length=463, Percent_Identity=24.4060475161987, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI310128183, Length=531, Percent_Identity=23.3521657250471, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1790113, Length=555, Percent_Identity=26.8468468468468, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI87082237, Length=470, Percent_Identity=24.8936170212766, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787251, Length=468, Percent_Identity=25.6410256410256, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24651739, Length=452, Percent_Identity=24.3362831858407, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161076631, Length=373, Percent_Identity=24.1286863270777, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28573698, Length=470, Percent_Identity=25.1063829787234, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI221459584, Length=411, Percent_Identity=23.3576642335766, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221459586, Length=442, Percent_Identity=22.8506787330317, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24651741, Length=477, Percent_Identity=21.3836477987421, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI221379702, Length=452, Percent_Identity=25.4424778761062, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364280, Length=389, Percent_Identity=22.3650385604113, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221459588, Length=465, Percent_Identity=22.3655913978495, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24645928, Length=395, Percent_Identity=25.0632911392405, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281362054, Length=398, Percent_Identity=23.3668341708543, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281362052, Length=398, Percent_Identity=23.3668341708543, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281362050, Length=398, Percent_Identity=23.3668341708543, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648056, Length=398, Percent_Identity=23.3668341708543, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356827, Length=398, Percent_Identity=23.3668341708543, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640370, Length=398, Percent_Identity=24.3718592964824, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920916, Length=399, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 62045; Mature: 62045

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALDWLVIGVFFLALIGIIVWVVRQKQNDSADYFLGGRDATWLAIGASIFASNIGSEHL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHH
IGLAGAGASSGMAMAHWEIQGWMILILGWVFVPFYSRSMVYTMPEFLERRYNPQSRTILS
EEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHH
VISLVSYVLTKVAVTVYAGGLVFQQVFGIKELWGIDFFWIAAIGLVVLTALYTIFGGMKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLYTSVLQTPILLLGSLIILVLGFKELGGWDEMMRVCGAVTVNDYGDTMTNLIRSNDDAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEECCCHHHHHHHHHCCCCCC
FPWLGALIGSAIIGFWYWCTDQFIVQRVLSGKNEKEARRGTIFGAYLKLLPVFLFLIPGM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFALHQKYIGAGGEGFLPMLANGTANADAAFPTLVAKLLPAGVKGLVVCGILAALMSSL
HHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ASLFNSSAMLFTIDFYKRFRPETPEKKLVGIGQIATVVIVILGILWIPIMRSVGDVLYTY
HHHHCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDVQSVLAPGIAAAFLLGICWKRTSAQGGMWGLIAGMIIGLTRLGAKVYYSNAGEVADS
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHEECCCCHHHHH
TFKYLFYDMNWLFFCGWMFLFCIIVVIVVSLATEAPTAEKIQGLVFGTATKEQKAATRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCHHHHHHHHCC
WDHWDIIHTVIILAITGAFYWYFW
CCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEALDWLVIGVFFLALIGIIVWVVRQKQNDSADYFLGGRDATWLAIGASIFASNIGSEHL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHH
IGLAGAGASSGMAMAHWEIQGWMILILGWVFVPFYSRSMVYTMPEFLERRYNPQSRTILS
EEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHH
VISLVSYVLTKVAVTVYAGGLVFQQVFGIKELWGIDFFWIAAIGLVVLTALYTIFGGMKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLYTSVLQTPILLLGSLIILVLGFKELGGWDEMMRVCGAVTVNDYGDTMTNLIRSNDDAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEECCCHHHHHHHHHCCCCCC
FPWLGALIGSAIIGFWYWCTDQFIVQRVLSGKNEKEARRGTIFGAYLKLLPVFLFLIPGM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFALHQKYIGAGGEGFLPMLANGTANADAAFPTLVAKLLPAGVKGLVVCGILAALMSSL
HHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ASLFNSSAMLFTIDFYKRFRPETPEKKLVGIGQIATVVIVILGILWIPIMRSVGDVLYTY
HHHHCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDVQSVLAPGIAAAFLLGICWKRTSAQGGMWGLIAGMIIGLTRLGAKVYYSNAGEVADS
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHEECCCCHHHHH
TFKYLFYDMNWLFFCGWMFLFCIIVVIVVSLATEAPTAEKIQGLVFGTATKEQKAATRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCHHHHHHHHCC
WDHWDIIHTVIILAITGAFYWYFW
CCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]