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The map label for this gene is ytfL [C]

Identifier: 29345558

GI number: 29345558

Start: 151535

End: 152824

Strand: Reverse

Name: ytfL [C]

Synonym: BT_0148

Alternate gene names: 29345558

Gene position: 152824-151535 (Counterclockwise)

Preceding gene: 29345559

Following gene: 29345557

Centisome position: 2.44

GC content: 47.13

Gene sequence:

>1290_bases
ATGGAATTTCTTATCATACTTCTCTTACTTGTACTGAATGGCATCTTTGCCATGTACGAAATTGCGCTGGTATCATCCAG
CAAAGCACGTCTCGAAACTCTCGCCGGAAAAGGCAACAAATCTGCACGTGGAGTACTGAAACAACTGGAAGAACCCGAAA
AGTTCTTGTCCACCATTCAAATCGGTATTACCCTGATCGGTATCGTATCCGGTGCCTATGGTGGTGTCGCTATCGCAGAC
GACCTTGTTCCGCTCTTCTCCCTCATACCGGGAGCGGAAGCCTATGCACGTAATCTGGCCATGATCACCACTGTGGTAAT
CATCACCTATCTCTCTCTTATCATCGGAGAGCTGGTTCCCAAGTCCATTGCCCTCAGCAATCCGGAACGGTACGCAACCT
TGTTCAGCCCGATTATGATTTTATTGACGAAAGTATCCTATCCGTTCGTCTGGTTTCTCAGTATCTCCACCCGCCTGCTG
AACAGAATCATCGGCGTAAAGAACGAAGAACGCCCGATGACACAGGAAGAGATCAAAATGATTCTCCACCAAAGCTCCGA
ACAGGGAGTGATCGACAAGGAAGAGACGGAAATGCTGCGTGATGTGTTCCGCTTCTCGGACAAACGTGCCAATGAACTGA
TGACGCACCGCAGAGACCTTGTCATCTTCCATCCCGACGATACGAAAGACAAGGTGATGAAGACAATCGAAGAAGAGCAC
TACAGCAAATATCTGTTGGTGGACGAGCGGAAAGACGAGATTATCGGTGTGGTATCCGTAAAGGATATTATTCTGATGGT
AGGCAATAAAAAAGAGTTCAATCTGCGCGAAATAGCCCGTCCGGCTCTGTTTATCCCCGAAAGTTTATATGCAAATAAAA
TTTTAGAGCTGTTCAAGAAGAACAAAAACAAGTTCGGAGTTGTTGTTAACGAGTATGGTAGTACAGAAGGTATCATTACC
CTGCACGACCTTACCGAAAGCATCTTCGGAGACATCCTTGAAGAGGACGATACGGAAGAGGAAGATATCGTCAGAAGACA
GGATGGTTCGATGCTGGTGGAGGCTTCGATGAACATCAAGGACTTTATGGAAGAGATGGGAATCCTATCTTATGAAGACC
TGGAGGACGAAGACTTCACGACCCTCGGAGGATTGGCAATGTTCCTGCTGGGCGGTATCCCGAAAGCCGGAGATATCTTC
ACCTACAAGAACCTGCAATTCGAAGTAGTAGATATGGACCGCGGACGGGTAGACAAACTGCTGGTCATCAAACGGGACGA
AGAAGAATAA

Upstream 100 bases:

>100_bases
CGCACCAATTGTTTATTAAAAAATCATTAATATACAGCACATATTTGCATGATGTCGTGATTTCATTTAATTTCACGGCA
ATAATCATTTAAATCCATTT

Downstream 100 bases:

>100_bases
AGAAAAAATAACCCGAGCAGTAAGCTCACTATATTTATATTAACTTAAAGCACTTAACGATGAAAAAAGTAATTATGTTA
GCAGCAGTCGTAGCTGCTTT

Product: putative hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MEFLIILLLLVLNGIFAMYEIALVSSSKARLETLAGKGNKSARGVLKQLEEPEKFLSTIQIGITLIGIVSGAYGGVAIAD
DLVPLFSLIPGAEAYARNLAMITTVVIITYLSLIIGELVPKSIALSNPERYATLFSPIMILLTKVSYPFVWFLSISTRLL
NRIIGVKNEERPMTQEEIKMILHQSSEQGVIDKEETEMLRDVFRFSDKRANELMTHRRDLVIFHPDDTKDKVMKTIEEEH
YSKYLLVDERKDEIIGVVSVKDIILMVGNKKEFNLREIARPALFIPESLYANKILELFKKNKNKFGVVVNEYGSTEGIIT
LHDLTESIFGDILEEDDTEEEDIVRRQDGSMLVEASMNIKDFMEEMGILSYEDLEDEDFTTLGGLAMFLLGGIPKAGDIF
TYKNLQFEVVDMDRGRVDKLLVIKRDEEE

Sequences:

>Translated_429_residues
MEFLIILLLLVLNGIFAMYEIALVSSSKARLETLAGKGNKSARGVLKQLEEPEKFLSTIQIGITLIGIVSGAYGGVAIAD
DLVPLFSLIPGAEAYARNLAMITTVVIITYLSLIIGELVPKSIALSNPERYATLFSPIMILLTKVSYPFVWFLSISTRLL
NRIIGVKNEERPMTQEEIKMILHQSSEQGVIDKEETEMLRDVFRFSDKRANELMTHRRDLVIFHPDDTKDKVMKTIEEEH
YSKYLLVDERKDEIIGVVSVKDIILMVGNKKEFNLREIARPALFIPESLYANKILELFKKNKNKFGVVVNEYGSTEGIIT
LHDLTESIFGDILEEDDTEEEDIVRRQDGSMLVEASMNIKDFMEEMGILSYEDLEDEDFTTLGGLAMFLLGGIPKAGDIF
TYKNLQFEVVDMDRGRVDKLLVIKRDEEE
>Mature_429_residues
MEFLIILLLLVLNGIFAMYEIALVSSSKARLETLAGKGNKSARGVLKQLEEPEKFLSTIQIGITLIGIVSGAYGGVAIAD
DLVPLFSLIPGAEAYARNLAMITTVVIITYLSLIIGELVPKSIALSNPERYATLFSPIMILLTKVSYPFVWFLSISTRLL
NRIIGVKNEERPMTQEEIKMILHQSSEQGVIDKEETEMLRDVFRFSDKRANELMTHRRDLVIFHPDDTKDKVMKTIEEEH
YSKYLLVDERKDEIIGVVSVKDIILMVGNKKEFNLREIARPALFIPESLYANKILELFKKNKNKFGVVVNEYGSTEGIIT
LHDLTESIFGDILEEDDTEEEDIVRRQDGSMLVEASMNIKDFMEEMGILSYEDLEDEDFTTLGGLAMFLLGGIPKAGDIF
TYKNLQFEVVDMDRGRVDKLLVIKRDEEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=378, Percent_Identity=29.3650793650794, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1790664, Length=428, Percent_Identity=30.8411214953271, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI145693175, Length=393, Percent_Identity=27.735368956743, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1786879, Length=248, Percent_Identity=27.8225806451613, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87082033, Length=282, Percent_Identity=26.5957446808511, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788119, Length=441, Percent_Identity=23.1292517006803, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48594; Mature: 48594

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLIILLLLVLNGIFAMYEIALVSSSKARLETLAGKGNKSARGVLKQLEEPEKFLSTIQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHH
IGITLIGIVSGAYGGVAIADDLVPLFSLIPGAEAYARNLAMITTVVIITYLSLIIGELVP
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSIALSNPERYATLFSPIMILLTKVSYPFVWFLSISTRLLNRIIGVKNEERPMTQEEIKM
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
ILHQSSEQGVIDKEETEMLRDVFRFSDKRANELMTHRRDLVIFHPDDTKDKVMKTIEEEH
HHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHH
YSKYLLVDERKDEIIGVVSVKDIILMVGNKKEFNLREIARPALFIPESLYANKILELFKK
CCEEEEEECCCCCEEEEEEHEEEEEEECCCCCCCHHHHCCCHHCCCHHHHHHHHHHHHHC
NKNKFGVVVNEYGSTEGIITLHDLTESIFGDILEEDDTEEEDIVRRQDGSMLVEASMNIK
CCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEECCCHH
DFMEEMGILSYEDLEDEDFTTLGGLAMFLLGGIPKAGDIFTYKNLQFEVVDMDRGRVDKL
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCCEE
LVIKRDEEE
EEEECCCCC
>Mature Secondary Structure
MEFLIILLLLVLNGIFAMYEIALVSSSKARLETLAGKGNKSARGVLKQLEEPEKFLSTIQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHH
IGITLIGIVSGAYGGVAIADDLVPLFSLIPGAEAYARNLAMITTVVIITYLSLIIGELVP
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSIALSNPERYATLFSPIMILLTKVSYPFVWFLSISTRLLNRIIGVKNEERPMTQEEIKM
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
ILHQSSEQGVIDKEETEMLRDVFRFSDKRANELMTHRRDLVIFHPDDTKDKVMKTIEEEH
HHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHH
YSKYLLVDERKDEIIGVVSVKDIILMVGNKKEFNLREIARPALFIPESLYANKILELFKK
CCEEEEEECCCCCEEEEEEHEEEEEEECCCCCCCHHHHCCCHHCCCHHHHHHHHHHHHHC
NKNKFGVVVNEYGSTEGIITLHDLTESIFGDILEEDDTEEEDIVRRQDGSMLVEASMNIK
CCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEECCCHH
DFMEEMGILSYEDLEDEDFTTLGGLAMFLLGGIPKAGDIFTYKNLQFEVVDMDRGRVDKL
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCCEE
LVIKRDEEE
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]