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The map label for this gene is uxuA [H]

Identifier: 29345539

GI number: 29345539

Start: 124349

End: 125536

Strand: Reverse

Name: uxuA [H]

Synonym: BT_0129

Alternate gene names: 29345539

Gene position: 125536-124349 (Counterclockwise)

Preceding gene: 29345540

Following gene: 29345535

Centisome position: 2.01

GC content: 43.77

Gene sequence:

>1188_bases
ATGATGGAAAAAACATGGAGATGGTTTGGCAAGAAAGACAAGATTACCTTGCCAATGCTCCGGCAAATAGGTGTGGAAGG
GATTGTTACAGCTTTGCACGACATACCGAACGGAGAAATATGGACAATAGAAGCGATTAATGCTCTGAAATCCTATATAG
AATCATACGGACTGCGCTGGTCTGTAGTAGAAAGTTTGCCCGTATGCGAAGCGATCAAATATGGTGGGACAGAACGTGAA
CAGTTGATAGAGAACTACAAAGTAAGCCTTACCAATCTAGGTAAATGTGGAATAAAAACTGTTTGCTATAACTTTATGCC
AGTCATCGACTGGATACGTACAGACTTGCAGTACCTCTGCCCCGACGGTACTAGCTCATTGTATTATGACCGTATCCGTT
TCGCCTATTTCGACATGAAGATACTGGAACGGGAAGGGGCTGAAAAGGATTATACGGAAGAAGAACTTCATAAAGTTTCC
GAACTGGATCAAGTGATCACCGAAAAAGAGAAGGATGATCTGATTGATACCATTATCGTTAAGACACAAGGATTTGTCAA
TGGGAACATCAAAGAAGGAGACAAAGAACCGGTCGTCCTTTTCAAACGGTTGTTAACTTTGTACAAAGATATTAACCGTG
ACATCCTGCGAGAAAATATGTGTCACTTTCTTTCTGCCATTATGCCGGTTTGCGAAGAATACGGAGTGAATATGTGCGTG
CATCCCGACGATCCTCCATTCCAGGTTCTTGGTCTTCCTCGTATCGTCACCAATGAAGAAGATATAGCCTGGTTCCTGAA
TGCAGTAGACAATCCGCACAACGGACTGACATTCTGTGCAGGTTCCTTGAGTGCCGGCGAACACAATGATACCCGCGAAT
TGGCAAAGAAGTTTGCTAAACGTACGCACTTTATACACCTACGCAGCACAGCCGCCATGCCGGGTGGAAACTTCATTGAA
AGTTCTCACCTGGCAGGAAGAGGACATATCATTGACCTTATCCGAATCTTTGAGAAAGAAAATCCGGGATTACCTATGCG
CATTGATCACGGGAGAATGATGCTGGGAGATGAAGACAAGGGGTATAATCCAGGCTATTCTTTTTATGGACGTATGCTGG
CACTGGCGCAAGTAGAGGGTATGATGACGGTAGTGGATGATGAAATAAAACGTCAGATGAAATTATGA

Upstream 100 bases:

>100_bases
ACAATTTTTGTGTAGCGAAGCTGCCAGTTTTGTAACCGGTGCAATGTTGCCTATCGACGGTGGATTCAGTGCATTCAGCG
GCGTATAAAGAGAAGAAACT

Downstream 100 bases:

>100_bases
TTCTCTTTCACCAGACATTGATGCAAAAAAGAAGGGAGAAGTCATATTTAACATCTCCCTTCTTTTTATCTATCATAGCA
ATAATCAATTTCTCTTTGAA

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MMEKTWRWFGKKDKITLPMLRQIGVEGIVTALHDIPNGEIWTIEAINALKSYIESYGLRWSVVESLPVCEAIKYGGTERE
QLIENYKVSLTNLGKCGIKTVCYNFMPVIDWIRTDLQYLCPDGTSSLYYDRIRFAYFDMKILEREGAEKDYTEEELHKVS
ELDQVITEKEKDDLIDTIIVKTQGFVNGNIKEGDKEPVVLFKRLLTLYKDINRDILRENMCHFLSAIMPVCEEYGVNMCV
HPDDPPFQVLGLPRIVTNEEDIAWFLNAVDNPHNGLTFCAGSLSAGEHNDTRELAKKFAKRTHFIHLRSTAAMPGGNFIE
SSHLAGRGHIIDLIRIFEKENPGLPMRIDHGRMMLGDEDKGYNPGYSFYGRMLALAQVEGMMTVVDDEIKRQMKL

Sequences:

>Translated_395_residues
MMEKTWRWFGKKDKITLPMLRQIGVEGIVTALHDIPNGEIWTIEAINALKSYIESYGLRWSVVESLPVCEAIKYGGTERE
QLIENYKVSLTNLGKCGIKTVCYNFMPVIDWIRTDLQYLCPDGTSSLYYDRIRFAYFDMKILEREGAEKDYTEEELHKVS
ELDQVITEKEKDDLIDTIIVKTQGFVNGNIKEGDKEPVVLFKRLLTLYKDINRDILRENMCHFLSAIMPVCEEYGVNMCV
HPDDPPFQVLGLPRIVTNEEDIAWFLNAVDNPHNGLTFCAGSLSAGEHNDTRELAKKFAKRTHFIHLRSTAAMPGGNFIE
SSHLAGRGHIIDLIRIFEKENPGLPMRIDHGRMMLGDEDKGYNPGYSFYGRMLALAQVEGMMTVVDDEIKRQMKL
>Mature_395_residues
MMEKTWRWFGKKDKITLPMLRQIGVEGIVTALHDIPNGEIWTIEAINALKSYIESYGLRWSVVESLPVCEAIKYGGTERE
QLIENYKVSLTNLGKCGIKTVCYNFMPVIDWIRTDLQYLCPDGTSSLYYDRIRFAYFDMKILEREGAEKDYTEEELHKVS
ELDQVITEKEKDDLIDTIIVKTQGFVNGNIKEGDKEPVVLFKRLLTLYKDINRDILRENMCHFLSAIMPVCEEYGVNMCV
HPDDPPFQVLGLPRIVTNEEDIAWFLNAVDNPHNGLTFCAGSLSAGEHNDTRELAKKFAKRTHFIHLRSTAAMPGGNFIE
SSHLAGRGHIIDLIRIFEKENPGLPMRIDHGRMMLGDEDKGYNPGYSFYGRMLALAQVEGMMTVVDDEIKRQMKL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=390, Percent_Identity=46.9230769230769, Blast_Score=356, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 45259; Mature: 45259

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEKTWRWFGKKDKITLPMLRQIGVEGIVTALHDIPNGEIWTIEAINALKSYIESYGLRW
CCCCHHHHCCCCCCEEHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCEE
SVVESLPVCEAIKYGGTEREQLIENYKVSLTNLGKCGIKTVCYNFMPVIDWIRTDLQYLC
EHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PDGTSSLYYDRIRFAYFDMKILEREGAEKDYTEEELHKVSELDQVITEKEKDDLIDTIIV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHH
KTQGFVNGNIKEGDKEPVVLFKRLLTLYKDINRDILRENMCHFLSAIMPVCEEYGVNMCV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
HPDDPPFQVLGLPRIVTNEEDIAWFLNAVDNPHNGLTFCAGSLSAGEHNDTRELAKKFAK
CCCCCCCEEECCCCEECCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
RTHFIHLRSTAAMPGGNFIESSHLAGRGHIIDLIRIFEKENPGLPMRIDHGRMMLGDEDK
HHEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCEEEECCCCC
GYNPGYSFYGRMLALAQVEGMMTVVDDEIKRQMKL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMEKTWRWFGKKDKITLPMLRQIGVEGIVTALHDIPNGEIWTIEAINALKSYIESYGLRW
CCCCHHHHCCCCCCEEHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCEE
SVVESLPVCEAIKYGGTEREQLIENYKVSLTNLGKCGIKTVCYNFMPVIDWIRTDLQYLC
EHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PDGTSSLYYDRIRFAYFDMKILEREGAEKDYTEEELHKVSELDQVITEKEKDDLIDTIIV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHH
KTQGFVNGNIKEGDKEPVVLFKRLLTLYKDINRDILRENMCHFLSAIMPVCEEYGVNMCV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
HPDDPPFQVLGLPRIVTNEEDIAWFLNAVDNPHNGLTFCAGSLSAGEHNDTRELAKKFAK
CCCCCCCEEECCCCEECCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
RTHFIHLRSTAAMPGGNFIESSHLAGRGHIIDLIRIFEKENPGLPMRIDHGRMMLGDEDK
HHEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCEEEECCCCC
GYNPGYSFYGRMLALAQVEGMMTVVDDEIKRQMKL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA