Click here to switch to the map view.

The map label for this gene is creB [H]

Identifier: 29144856

GI number: 29144856

Start: 4778770

End: 4779459

Strand: Direct

Name: creB [H]

Synonym: t4627

Alternate gene names: 29144856

Gene position: 4778770-4779459 (Clockwise)

Preceding gene: 29144855

Following gene: 29144857

Centisome position: 99.72

GC content: 57.97

Gene sequence:

>690_bases
ATGCAGCAACCGCAGGTCTGGTTAGTCGAGGATGAACAGGGAATCGCCGATACGCTCATCTACACCCTGCAACTGGAAGG
GTTTACCGTTGAGCTATTCGCTCGCGGGCTGCCCGCGCTGGAAAAAGCGCGTCAGCAACGGCCAGATGCGGTGATTCTCG
ATGTGGGACTACCGGATATCAGCGGCTTTGAGCTGTGTCGGCAGTTGCTGGAGCGTCATCCGGCGCTGCCGATTCTTTTC
CTGACTGCCCGTAGCGATGAAGTGGATCGATTGCTTGGTCTGGAGATCGGCGCAGATGATTATGTCGCCAAGCCGTTCTC
GCCGCGCGAAGTGAGCGCCCGCGTGCGCACGCTGCTGCGCCGGGTGAAAAAGTTTGCTGCGCCGTCGCCGGTGGTGCGTA
CCGGACATTTTGATCTCAATGAACCGGCGGCGCAGATCGCCTGGTTTGGTACGCCGCTCTCGCTGACGCGTTATGAGTTT
CTGCTCCTTAAAACCCTGCTGCTGTCGCCGGAGCGCGTGTACTCGTGCCAGCAATTGATGGATATTGTCTGGTCTGATGC
CCAAGAGACCTTCGATCGGACGGTCGATACGCACATCAAAACCCTGCGCGCTAAACTACGCGCGATCAACCCGGATCTCT
CGCCAATTAACACGCATCGTGGAATGGGATACAGCCTGAGGAGCATCTGA

Upstream 100 bases:

>100_bases
GGCGTATCTGGCCTACTCCGACAAAGTGGTCGACGGGTCGCCGAAGAACGCCATCAGCGCGGTGCCGGTCATGCCGTGGC
GACAATAACAGGGAAAGCGT

Downstream 100 bases:

>100_bases
TGCGCATCGGAATGCGTTTGCTGCTGGGCTACTTTCTTATTGTCGCCGTCGCCGCCGTGTTTGTGCTGTCTATCTTTGTT
CAGGAGATAAAGCCGGGCGT

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDISGFELCRQLLERHPALPILF
LTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLRRVKKFAAPSPVVRTGHFDLNEPAAQIAWFGTPLSLTRYEF
LLLKTLLLSPERVYSCQQLMDIVWSDAQETFDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSI

Sequences:

>Translated_229_residues
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDISGFELCRQLLERHPALPILF
LTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLRRVKKFAAPSPVVRTGHFDLNEPAAQIAWFGTPLSLTRYEF
LLLKTLLLSPERVYSCQQLMDIVWSDAQETFDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSI
>Mature_229_residues
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDISGFELCRQLLERHPALPILF
LTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLRRVKKFAAPSPVVRTGHFDLNEPAAQIAWFGTPLSLTRYEF
LLLKTLLLSPERVYSCQQLMDIVWSDAQETFDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSI

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=83.4061135371179, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=42.2907488986784, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=34.9557522123894, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=36.7713004484305, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.2678571428571, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=36.4035087719298, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=35.8744394618834, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.7586206896552, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=32.4324324324324, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=33.9130434782609, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=33.6363636363636, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=30.2222222222222, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790299, Length=135, Percent_Identity=32.5925925925926, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=25.764192139738, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790437, Length=142, Percent_Identity=28.8732394366197, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25964; Mature: 25964

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDI
CCCCCEEEEECCCCHHHHEEEEEEECCEEHHHHHCCCHHHHHHHHCCCCEEEEECCCCCC
SGFELCRQLLERHPALPILFLTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLR
CHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHH
RVKKFAAPSPVVRTGHFDLNEPAAQIAWFGTPLSLTRYEFLLLKTLLLSPERVYSCQQLM
HHHHHCCCCCCEECCCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHH
DIVWSDAQETFDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDI
CCCCCEEEEECCCCHHHHEEEEEEECCEEHHHHHCCCHHHHHHHHCCCCEEEEECCCCCC
SGFELCRQLLERHPALPILFLTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLR
CHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHH
RVKKFAAPSPVVRTGHFDLNEPAAQIAWFGTPLSLTRYEFLLLKTLLLSPERVYSCQQLM
HHHHHCCCCCCEECCCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHH
DIVWSDAQETFDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]