Click here to switch to the map view.

The map label for this gene is avtA [H]

Identifier: 29144132

GI number: 29144132

Start: 3979610

End: 3980860

Strand: Reverse

Name: avtA [H]

Synonym: t3854

Alternate gene names: 29144132

Gene position: 3980860-3979610 (Counterclockwise)

Preceding gene: 29144133

Following gene: 29144129

Centisome position: 83.07

GC content: 53.16

Gene sequence:

>1251_bases
ATGACATTTTCACTTTTCGGCGATAAATTTACCCGCCATTCAGGCATTACCCGCCTGATGGAGGATCTCAACGACGGCTT
ACGCACGCCAGGCGCCATCATGCTTGGCGGCGGTAACCCGGCACACATCCCTGCAATGCAGGATTATTTCCAGACGCTAC
TGACAGAGATGGTAGAAAGCGGCAAAGCCGCTGATGCGCTTTGTAATTATGACGGTCCCCAGGGAAAAACGGCGCTACTG
AATGCACTGGCCGTACTGCTACGTGAAACGCTGGGATGGGATATCGAACCACAGAATATTGCGCTAACAAATGGCAGTCA
GAGCGCGTTTTTCTACTTATTTAATCTCTTCGCCGGACGTCGCGCCGACGGCAGTACGAAAAAGGTACTATTCCCGCTTG
CGCCGGAATACATCGGCTATGCGGATTCCGGTCTGGAAGACGACCTCTTCGTTTCGGCGCGCCCGAATATTGAGCTGCTG
CCGGAAGGCCAGTTTAAGTATCACGTCGATTTTGAGCATCTGCACATCGGCGAAGAAACGGGGATGATTTGCGTCTCGCG
CCCGACCAACCCAACCGGTAACGTTATCACCGACGAAGAGCTGATGAAGCTGGACAGACTGGCGAATCAGCACAACATCC
CACTGGTGATTGATAACGCTTACGGTGTACCGTTTCCGGGCATTATCTTTAGCGAGGCGCGCCCGCTGTGGAACCCCAAT
ATTATCCTATGCATGAGCCTCTCAAAGCTGGGGCTGCCCGGTTCCCGCTGCGGGATTATCATCGCCAATGATAAGACGAT
TACCGCCATTGCCAACATGAACGGCATCATCAGCCTTGCGCCCGGGGGCATGGGCCCGGCGATGATGTGCGAAATGATTA
AGCGTAACGATCTGCTGCGGCTGTCGGAAACGGTTATCAAACCTTTCTACTATCAGCGCGTTCAACAGACGATCGCGATC
ATTCGTCGCTATTTATCCGAAGAACGCTGCCTGATTCATAAACCAGAAGGCGCAATATTTTTGTGGCTGTGGTTTAAAGA
TCTGCCGATTACCACCGAGCTACTCTATCAACGCTTGAAAGCGCGCGGCGTGCTGATGGTGCCGGGCCACTATTTCTTTC
CCGGACTGGATAAACCCTGGCCGCACACACACCAGTGTATGCGGATGAACTACGTGCCTGAACCGGATAAAATCGAGGCG
GGCGTAAAAATTCTGGCAGAAGAGATAGAACGCGCCTGGCGTGAAGGCTGA

Upstream 100 bases:

>100_bases
GCATAAAACATCAATACCACCGCCTGTCCCCCATTTGCGCCCCGCCATTTGTAGCGTTATGGTTATCCACTTTGACAGAC
AGTTCGATAGATCACCCGTT

Downstream 100 bases:

>100_bases
CGGTTATTCCGGCCATTATGCAGGCCGGAACGATGTTCAGAAAGGTTGAGAATAGAGGCGCTGGCGCTGCACGTGTGTTG
CGTCAACGCACTGTAACGCA

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MTFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAHIPAMQDYFQTLLTEMVESGKAADALCNYDGPQGKTALL
NALAVLLRETLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADSGLEDDLFVSARPNIELL
PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELMKLDRLANQHNIPLVIDNAYGVPFPGIIFSEARPLWNPN
IILCMSLSKLGLPGSRCGIIIANDKTITAIANMNGIISLAPGGMGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQQTIAI
IRRYLSEERCLIHKPEGAIFLWLWFKDLPITTELLYQRLKARGVLMVPGHYFFPGLDKPWPHTHQCMRMNYVPEPDKIEA
GVKILAEEIERAWREG

Sequences:

>Translated_416_residues
MTFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAHIPAMQDYFQTLLTEMVESGKAADALCNYDGPQGKTALL
NALAVLLRETLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADSGLEDDLFVSARPNIELL
PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELMKLDRLANQHNIPLVIDNAYGVPFPGIIFSEARPLWNPN
IILCMSLSKLGLPGSRCGIIIANDKTITAIANMNGIISLAPGGMGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQQTIAI
IRRYLSEERCLIHKPEGAIFLWLWFKDLPITTELLYQRLKARGVLMVPGHYFFPGLDKPWPHTHQCMRMNYVPEPDKIEA
GVKILAEEIERAWREG
>Mature_415_residues
TFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAHIPAMQDYFQTLLTEMVESGKAADALCNYDGPQGKTALLN
ALAVLLRETLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADSGLEDDLFVSARPNIELLP
EGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELMKLDRLANQHNIPLVIDNAYGVPFPGIIFSEARPLWNPNI
ILCMSLSKLGLPGSRCGIIIANDKTITAIANMNGIISLAPGGMGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQQTIAII
RRYLSEERCLIHKPEGAIFLWLWFKDLPITTELLYQRLKARGVLMVPGHYFFPGLDKPWPHTHQCMRMNYVPEPDKIEAG
VKILAEEIERAWREG

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=415, Percent_Identity=92.289156626506, Blast_Score=798, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 46600; Mature: 46468

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAHIPAMQDYFQTLLTEMVES
CEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHC
GKAADALCNYDGPQGKTALLNALAVLLRETLGWDIEPQNIALTNGSQSAFFYLFNLFAGR
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCC
RADGSTKKVLFPLAPEYIGYADSGLEDDLFVSARPNIELLPEGQFKYHVDFEHLHIGEET
CCCCCCCEEEEECCHHHHCCCCCCCCCCEEEECCCCEEEEECCCEEEEEEHHEEEECCCC
GMICVSRPTNPTGNVITDEELMKLDRLANQHNIPLVIDNAYGVPFPGIIFSEARPLWNPN
CEEEEECCCCCCCCEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCCCCCCCC
IILCMSLSKLGLPGSRCGIIIANDKTITAIANMNGIISLAPGGMGPAMMCEMIKRNDLLR
EEEEEEHHHCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHH
LSETVIKPFYYQRVQQTIAIIRRYLSEERCLIHKPEGAIFLWLWFKDLPITTELLYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHH
ARGVLMVPGHYFFPGLDKPWPHTHQCMRMNYVPEPDKIEAGVKILAEEIERAWREG
HCCEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAHIPAMQDYFQTLLTEMVES
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHC
GKAADALCNYDGPQGKTALLNALAVLLRETLGWDIEPQNIALTNGSQSAFFYLFNLFAGR
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCC
RADGSTKKVLFPLAPEYIGYADSGLEDDLFVSARPNIELLPEGQFKYHVDFEHLHIGEET
CCCCCCCEEEEECCHHHHCCCCCCCCCCEEEECCCCEEEEECCCEEEEEEHHEEEECCCC
GMICVSRPTNPTGNVITDEELMKLDRLANQHNIPLVIDNAYGVPFPGIIFSEARPLWNPN
CEEEEECCCCCCCCEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCCCCCCCC
IILCMSLSKLGLPGSRCGIIIANDKTITAIANMNGIISLAPGGMGPAMMCEMIKRNDLLR
EEEEEEHHHCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHH
LSETVIKPFYYQRVQQTIAIIRRYLSEERCLIHKPEGAIFLWLWFKDLPITTELLYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHH
ARGVLMVPGHYFFPGLDKPWPHTHQCMRMNYVPEPDKIEAGVKILAEEIERAWREG
HCCEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]