Click here to switch to the map view.

The map label for this gene is sgbH [H]

Identifier: 29144123

GI number: 29144123

Start: 3970474

End: 3971136

Strand: Reverse

Name: sgbH [H]

Synonym: t3844

Alternate gene names: 29144123

Gene position: 3971136-3970474 (Counterclockwise)

Preceding gene: 29144124

Following gene: 29144122

Centisome position: 82.87

GC content: 60.78

Gene sequence:

>663_bases
ATGAGCCGACCATTACTGCAACTGGCGCTCGACCACACCAGTCTGGAAGCAGCCCAGCGCGATGTCGCCCTGCTACAGGA
TCATGTCGATATCGTTGAGGCCGGAACCATCCTTTGTTTAACCGAAGGCCTTAGCGCGGTGAAAGCCCTGCGAGCGCAGT
GCCCGGAAAAAATCATCGTCGCCGACTGGAAAGTGGCCGATGCCGGTGAAACCCTGGCGCAGCAGGCTTTTAGCGCTGGC
GCTAACTGGATGACTATCATCTGCGCCGCGCCGCTCGCGACCGTCGAGAAAGGCCATGCCGTCGCGCAATCCTGCGGCGG
TGAAATTCAAATGGAACTGTTCGGCAACTGGACGCTGGACGACGCCCGAGACTGGTATCGCGTCGGGGTTCGCCAGGCGA
TTTACCACCGCGGACACGATGCGCAGGCCAGCGGGCAGCAGTGGGGAGAAGCGGACCTGGCGCGTATGAAGGCGTTGTCC
GACATCGGCCTTGAACTATCGATTACCGGCGGCATTACCCCAGCGGATCTGCCGCTGTTCCGCGACATTAACGTTAAGGC
ATTTATCGCCGGACGTGCGCTGGCAGGTGCCGCCCATCCGGCGCAGGTCGCCGCCGAATTCCACGCCCAAATTGACGCCA
TTTGGGGAGAAAAGCATGCGTAA

Upstream 100 bases:

>100_bases
ACATGACCGCGCACGCCCTCTACCAGCGCAAATACCGCCAATACCAGGATTTGATTGAAGCACTACAGGGCTATCACGCC
CGTATTAAGGAGCACGCATT

Downstream 100 bases:

>100_bases
TCATCCATTAGGTATTTACGAGAAAGCACTGGCGAAAGATCTCAGTTGGCCAGAGCGGCTGGTGCTGGCAAAAAGCTGCG
GTTTTGATTTTGTTGAGATG

Product: 3-keto-L-gulonate-6-phosphate decarboxylase

Products: NA

Alternate protein names: KGPDC; 3-dehydro-L-gulonate-6-phosphate decarboxylase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIVADWKVADAGETLAQQAFSAG
ANWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLDDARDWYRVGVRQAIYHRGHDAQASGQQWGEADLARMKALS
DIGLELSITGGITPADLPLFRDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWGEKHA

Sequences:

>Translated_220_residues
MSRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIVADWKVADAGETLAQQAFSAG
ANWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLDDARDWYRVGVRQAIYHRGHDAQASGQQWGEADLARMKALS
DIGLELSITGGITPADLPLFRDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWGEKHA
>Mature_219_residues
SRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIVADWKVADAGETLAQQAFSAGA
NWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLDDARDWYRVGVRQAIYHRGHDAQASGQQWGEADLARMKALSD
IGLELSITGGITPADLPLFRDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWGEKHA

Specific function: Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. May be involved in the utilization of 2,3- diketo-L-gulonate [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. KGPDC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790006, Length=220, Percent_Identity=89.5454545454545, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1790640, Length=216, Percent_Identity=45.3703703703704, Blast_Score=210, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.85 [H]

Molecular weight: Translated: 23539; Mature: 23408

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCEEE
ADWKVADAGETLAQQAFSAGANWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLD
ECCEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCH
DARDWYRVGVRQAIYHRGHDAQASGQQWGEADLARMKALSDIGLELSITGGITPADLPLF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEE
RDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWGEKHA
ECCCEEEEEECHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCEEE
ADWKVADAGETLAQQAFSAGANWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLD
ECCEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCH
DARDWYRVGVRQAIYHRGHDAQASGQQWGEADLARMKALSDIGLELSITGGITPADLPLF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEE
RDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWGEKHA
ECCCEEEEEECHHHCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 9274005; 11741871 [H]