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The map label for this gene is deoR [H]

Identifier: 29144015

GI number: 29144015

Start: 3838597

End: 3839382

Strand: Reverse

Name: deoR [H]

Synonym: t3724

Alternate gene names: 29144015

Gene position: 3839382-3838597 (Counterclockwise)

Preceding gene: 29144030

Following gene: 29144011

Centisome position: 80.12

GC content: 51.91

Gene sequence:

>786_bases
ATGGAGACCAAGCAAAAAGAACGTATCCGACGCTTGATGGAGTTACTGAAAAAGACCGATCGAATCCATCTGAAAGACGC
CGCGCGGATGCTGGAAGTTTCGGTGATGACCATTCGCCGCGATCTCAGCCAGGATGATGACCCTTTACCGCTGACGCTGC
TCGGCGGCTATATCGTCATGGTAAATAAGCCTGCGTCTTCAACCAATATGCCGCTGCCGGCGAAAAAGACGCATCATCGG
GACGACCTTCCCGTTGCGATCTTGGCCGCCGGCCTGGTGCGTGAAAACGATCTGGTTTTTTTTGATAACGGTCCGGAAAT
GCCATTAGTCATCAGCATGATACCGGATGATATTACCTTTACCGGGATTTGCTACTCGCATCGGGTATTTATCGCGCTGA
ATGAAAAGCCTAATGCCACAGCGATTCTGTGCGGCGGCACCTATCGGGCCAAGAGCGATGCCTTTTATGATGCCAATAAT
CCTTCGGCGCTGGATTCGCTTAATCCGCGCAAAGTGTTTATTTCCGCCAGCGGCGTACATGAACATTTTGGCGTGAGCTG
GTTTAACCCGGATGATCTTGCCGCCAAACGTAAAGCGATGGAGCGCGGTCTGCGCAAAATTTTGCTGGCGCGTCACGCCC
TGTTTGATGAGGTCGCGCCTGCCAGCATTGGTCCGCTTTCTGCCTTTGATGTCCTGATTAGCGATCGCCCATTACCGACA
GATTATGCCGTTCACTGTCGGAATGGTTCCGTCAAAGTCATCACGCCTGATTCGGAAAGTGAATAA

Upstream 100 bases:

>100_bases
TCCTGACGGCCAGACGTATAGTAGTGCCACACTGTAATGTTCTCAGAAACACATAAATGTTACTGATGGAACATAACAAC
ATGATTTGCGGAGAGGGTGA

Downstream 100 bases:

>100_bases
CTTACTCAAAAAAGACGGCAATTTTATTGAACATGGTGGGATCGGACTGGTTTCGTACCACCTTCGCCACGTCTTCCAGT
TTATCGATCTGACTTATCAT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLSQDDDPLPLTLLGGYIVMVNKPASSTNMPLPAKKTHHR
DDLPVAILAAGLVRENDLVFFDNGPEMPLVISMIPDDITFTGICYSHRVFIALNEKPNATAILCGGTYRAKSDAFYDANN
PSALDSLNPRKVFISASGVHEHFGVSWFNPDDLAAKRKAMERGLRKILLARHALFDEVAPASIGPLSAFDVLISDRPLPT
DYAVHCRNGSVKVITPDSESE

Sequences:

>Translated_261_residues
METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLSQDDDPLPLTLLGGYIVMVNKPASSTNMPLPAKKTHHR
DDLPVAILAAGLVRENDLVFFDNGPEMPLVISMIPDDITFTGICYSHRVFIALNEKPNATAILCGGTYRAKSDAFYDANN
PSALDSLNPRKVFISASGVHEHFGVSWFNPDDLAAKRKAMERGLRKILLARHALFDEVAPASIGPLSAFDVLISDRPLPT
DYAVHCRNGSVKVITPDSESE
>Mature_261_residues
METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLSQDDDPLPLTLLGGYIVMVNKPASSTNMPLPAKKTHHR
DDLPVAILAAGLVRENDLVFFDNGPEMPLVISMIPDDITFTGICYSHRVFIALNEKPNATAILCGGTYRAKSDAFYDANN
PSALDSLNPRKVFISASGVHEHFGVSWFNPDDLAAKRKAMERGLRKILLARHALFDEVAPASIGPLSAFDVLISDRPLPT
DYAVHCRNGSVKVITPDSESE

Specific function: This protein is one of the repressors that regulate the expression of deoCABD genes, which encode nucleotide and deoxy ribonucleotide catabolizing enzymes. It also negatively regulates the expression of nupG (a transport protein) and tsx (a pore- forming

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787063, Length=255, Percent_Identity=38.8235294117647, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1790753, Length=262, Percent_Identity=21.3740458015267, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789059, Length=261, Percent_Identity=24.5210727969349, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28990; Mature: 28990

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLSQDDDPLPLTLLGGYIVM
CCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEE
VNKPASSTNMPLPAKKTHHRDDLPVAILAAGLVRENDLVFFDNGPEMPLVISMIPDDITF
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCEEEECCCCCCCEEEEECCCCCEE
TGICYSHRVFIALNEKPNATAILCGGTYRAKSDAFYDANNPSALDSLNPRKVFISASGVH
EEEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCEECCCCCCHHCCCCCCEEEEEECCCH
EHFGVSWFNPDDLAAKRKAMERGLRKILLARHALFDEVAPASIGPLSAFDVLISDRPLPT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEECCCCCCC
DYAVHCRNGSVKVITPDSESE
CEEEEECCCCEEEECCCCCCC
>Mature Secondary Structure
METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLSQDDDPLPLTLLGGYIVM
CCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEE
VNKPASSTNMPLPAKKTHHRDDLPVAILAAGLVRENDLVFFDNGPEMPLVISMIPDDITF
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCEEEECCCCCCCEEEEECCCCCEE
TGICYSHRVFIALNEKPNATAILCGGTYRAKSDAFYDANNPSALDSLNPRKVFISASGVH
EEEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCEECCCCCCHHCCCCCCEEEEEECCCH
EHFGVSWFNPDDLAAKRKAMERGLRKILLARHALFDEVAPASIGPLSAFDVLISDRPLPT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEECCCCCCC
DYAVHCRNGSVKVITPDSESE
CEEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]