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The map label for this gene is rocC [H]

Identifier: 29141022

GI number: 29141022

Start: 581108

End: 582397

Strand: Direct

Name: rocC [H]

Synonym: t0507

Alternate gene names: 29141022

Gene position: 581108-582397 (Clockwise)

Preceding gene: 29141021

Following gene: 29141023

Centisome position: 12.13

GC content: 54.42

Gene sequence:

>1290_bases
ATGGATACCCTGCAACAATCTCCGCCAGCAGAGCCTGAAGGCGGTCTGCGGCGTAACCTGAAGAAGCGGCACCTGCTGAT
GATGTCGCTGGGCGGCACGATTGGCACCGGCTTATTTATCGGCATTGCCGAACCGTTAAGCAGCGTCGGGCCGGCGGGAA
CCTTACTGGCCTATCTGTTTGCCGGAACCATTATGCTGGCGACGATGATGTGTCTTGGCGAATTATCATGCGCCTTTCCT
CACTCCGGTTCATTTCAACATTACGCGCTGATGTTTATGCCGTCACCTTGCTGGAGCTATACCATTGGCTGGCTTTACTG
GTTTAGCTGGGTCTTTTCCCTGGCAGCCGACCTCACTGCCGCAGGGTTTATTGCTCACCAGTTTTTCCCCGCGGTTCCGG
TATATATGTTCTGCCTGGCGATTCTGCTCATCCTGACGGCTATCAATCTCACCTCCGCAAAAAGTTTTGGCGAATGCGAA
TACTGGCTTTCGGCCATTAAGGTCTTCGCGATCGTGCTGTTTATCTGCGCGGGCGGGGTCATGATCTACTCGCTAATGGG
CCATAGTGACTGGCACCCGACGTTAAAAACAGACGGAATGTGGTTTCCCCACGGTTGGGAGCAAATTGTGGTCTGTATGA
CGATCGTGATTTACTCCTTCCAGGGGGTGGAACTGGTCGGAAATGCGGCAGGGGAGACCGAATCGCCGCACATTATTTTA
CCGAAGGTGATCCTGGGGATCGGTCTCAGAATCATTTTGTTTTACGGCCTGGCGATTGCGGTGCTGGCGCTGGTCTATCC
GCATGAACTGACGCCAAATGGACAAAGTCCCTTTGTATGGGTATTCTCCCACGCGGGCATTCCGGGGGCGGATACGCTGA
TGACGCTGGTGATCTTTTCCGCCGCGGTTTCTGCCGCTAACTCGGCCATTTACGCCAGTTCGCGTATGCTGTGGTCTATG
GCGGGCGATCGCTTTGCGCCAGCCTGCTTTGGTAAAACGAACGGCGGCGGCGTGCCGGTGTATGCTATTTTAATCACGGC
CTTGCTGGCGTTGGTGTCGTTGCTGACCCGCTATATTCCCGCACAGCAATTTTATTTATATCTGATCGCCAGTACCGGGC
AGGTGGGTTGCCTGGCATGGATAACCATCGGATGGTGCCAGTATCGCTTCCGACAATCGGTGCGTAATGGCACGTACGCC
AGCGATTTGCTACGCTATCGATCGCCGCTTTTTCCCTGGACGGCCCGATTTGTCATTATCACCAATTTTGCCATTATGGT
CGGCACCTAG

Upstream 100 bases:

>100_bases
CCAGACCAAAGGCGTCGCCTGGAGGTTTACGCGTTAACGCATAACCGCCGCGGCTATGTCGCGGCGGCATCTTTGACCTC
ACGAAAGACAGGGAGTAACG

Downstream 100 bases:

>100_bases
TTTAGTGAGCAGGGAGTAGTGATAATGTTGGTTGAGCTGGCTTTTATGATAGGGATTCTTTTGTCATGGTATCTCTTCAG
ACCCACTTTGAGCCGGTTAC

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDTLQQSPPAEPEGGLRRNLKKRHLLMMSLGGTIGTGLFIGIAEPLSSVGPAGTLLAYLFAGTIMLATMMCLGELSCAFP
HSGSFQHYALMFMPSPCWSYTIGWLYWFSWVFSLAADLTAAGFIAHQFFPAVPVYMFCLAILLILTAINLTSAKSFGECE
YWLSAIKVFAIVLFICAGGVMIYSLMGHSDWHPTLKTDGMWFPHGWEQIVVCMTIVIYSFQGVELVGNAAGETESPHIIL
PKVILGIGLRIILFYGLAIAVLALVYPHELTPNGQSPFVWVFSHAGIPGADTLMTLVIFSAAVSAANSAIYASSRMLWSM
AGDRFAPACFGKTNGGGVPVYAILITALLALVSLLTRYIPAQQFYLYLIASTGQVGCLAWITIGWCQYRFRQSVRNGTYA
SDLLRYRSPLFPWTARFVIITNFAIMVGT

Sequences:

>Translated_429_residues
MDTLQQSPPAEPEGGLRRNLKKRHLLMMSLGGTIGTGLFIGIAEPLSSVGPAGTLLAYLFAGTIMLATMMCLGELSCAFP
HSGSFQHYALMFMPSPCWSYTIGWLYWFSWVFSLAADLTAAGFIAHQFFPAVPVYMFCLAILLILTAINLTSAKSFGECE
YWLSAIKVFAIVLFICAGGVMIYSLMGHSDWHPTLKTDGMWFPHGWEQIVVCMTIVIYSFQGVELVGNAAGETESPHIIL
PKVILGIGLRIILFYGLAIAVLALVYPHELTPNGQSPFVWVFSHAGIPGADTLMTLVIFSAAVSAANSAIYASSRMLWSM
AGDRFAPACFGKTNGGGVPVYAILITALLALVSLLTRYIPAQQFYLYLIASTGQVGCLAWITIGWCQYRFRQSVRNGTYA
SDLLRYRSPLFPWTARFVIITNFAIMVGT
>Mature_429_residues
MDTLQQSPPAEPEGGLRRNLKKRHLLMMSLGGTIGTGLFIGIAEPLSSVGPAGTLLAYLFAGTIMLATMMCLGELSCAFP
HSGSFQHYALMFMPSPCWSYTIGWLYWFSWVFSLAADLTAAGFIAHQFFPAVPVYMFCLAILLILTAINLTSAKSFGECE
YWLSAIKVFAIVLFICAGGVMIYSLMGHSDWHPTLKTDGMWFPHGWEQIVVCMTIVIYSFQGVELVGNAAGETESPHIIL
PKVILGIGLRIILFYGLAIAVLALVYPHELTPNGQSPFVWVFSHAGIPGADTLMTLVIFSAAVSAANSAIYASSRMLWSM
AGDRFAPACFGKTNGGGVPVYAILITALLALVSLLTRYIPAQQFYLYLIASTGQVGCLAWITIGWCQYRFRQSVRNGTYA
SDLLRYRSPLFPWTARFVIITNFAIMVGT

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081708, Length=417, Percent_Identity=39.0887290167866, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1788480, Length=429, Percent_Identity=37.7622377622378, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI1789017, Length=419, Percent_Identity=34.8448687350835, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1786302, Length=417, Percent_Identity=33.5731414868106, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI87081915, Length=410, Percent_Identity=35.1219512195122, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1786789, Length=417, Percent_Identity=32.1342925659472, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI48994972, Length=409, Percent_Identity=35.4523227383863, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1790653, Length=406, Percent_Identity=33.2512315270936, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1786602, Length=403, Percent_Identity=33.9950372208437, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87082023, Length=332, Percent_Identity=24.3975903614458, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=441, Percent_Identity=31.2925170068027, Blast_Score=219, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6324061, Length=443, Percent_Identity=31.8284424379233, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6324059, Length=437, Percent_Identity=31.8077803203661, Blast_Score=192, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6324553, Length=426, Percent_Identity=27.6995305164319, Blast_Score=181, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322892, Length=418, Percent_Identity=31.3397129186603, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6324990, Length=457, Percent_Identity=29.5404814004376, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6320717, Length=437, Percent_Identity=24.4851258581236, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6321629, Length=427, Percent_Identity=27.4004683840749, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322967, Length=441, Percent_Identity=29.2517006802721, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324924, Length=456, Percent_Identity=27.6315789473684, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321053, Length=422, Percent_Identity=27.7251184834123, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6319824, Length=431, Percent_Identity=22.5058004640371, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319543, Length=432, Percent_Identity=22.9166666666667, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6319542, Length=430, Percent_Identity=23.7209302325581, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6319608, Length=371, Percent_Identity=27.4932614555256, Blast_Score=129, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6320251, Length=441, Percent_Identity=23.5827664399093, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324981, Length=440, Percent_Identity=28.8636363636364, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320364, Length=481, Percent_Identity=22.2453222453222, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667468, Length=384, Percent_Identity=21.09375, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 46882; Mature: 46882

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLQQSPPAEPEGGLRRNLKKRHLLMMSLGGTIGTGLFIGIAEPLSSVGPAGTLLAYLF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AGTIMLATMMCLGELSCAFPHSGSFQHYALMFMPSPCWSYTIGWLYWFSWVFSLAADLTA
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AGFIAHQFFPAVPVYMFCLAILLILTAINLTSAKSFGECEYWLSAIKVFAIVLFICAGGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MIYSLMGHSDWHPTLKTDGMWFPHGWEQIVVCMTIVIYSFQGVELVGNAAGETESPHIIL
HHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCEEH
PKVILGIGLRIILFYGLAIAVLALVYPHELTPNGQSPFVWVFSHAGIPGADTLMTLVIFS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
AAVSAANSAIYASSRMLWSMAGDRFAPACFGKTNGGGVPVYAILITALLALVSLLTRYIP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
AQQFYLYLIASTGQVGCLAWITIGWCQYRFRQSVRNGTYASDLLRYRSPLFPWTARFVII
HHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHE
TNFAIMVGT
EEEEEEECC
>Mature Secondary Structure
MDTLQQSPPAEPEGGLRRNLKKRHLLMMSLGGTIGTGLFIGIAEPLSSVGPAGTLLAYLF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AGTIMLATMMCLGELSCAFPHSGSFQHYALMFMPSPCWSYTIGWLYWFSWVFSLAADLTA
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AGFIAHQFFPAVPVYMFCLAILLILTAINLTSAKSFGECEYWLSAIKVFAIVLFICAGGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MIYSLMGHSDWHPTLKTDGMWFPHGWEQIVVCMTIVIYSFQGVELVGNAAGETESPHIIL
HHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCEEH
PKVILGIGLRIILFYGLAIAVLALVYPHELTPNGQSPFVWVFSHAGIPGADTLMTLVIFS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
AAVSAANSAIYASSRMLWSMAGDRFAPACFGKTNGGGVPVYAILITALLALVSLLTRYIP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
AQQFYLYLIASTGQVGCLAWITIGWCQYRFRQSVRNGTYASDLLRYRSPLFPWTARFVII
HHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHE
TNFAIMVGT
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]