BacMap

Definition	Tropheryma whipplei TW08/27, complete genome.
Accession	NC_004551
Length	925,938

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The map label for this gene is dnaJ2 [H]

Identifier: 28572901

GI number: 28572901

Start: 857155

End: 858018

Strand: Reverse

Name: dnaJ2 [H]

Synonym: TW760

Alternate gene names: 28572901

Gene position: 858018-857155 (Counterclockwise)

Preceding gene: 28572902

Following gene: 28572900

Centisome position: 92.66

GC content: 45.49

Gene sequence:

>864_bases
ATGGTTAGTCAAGACTGGCTTGAGAAGGACTTTTATGCGGTTCTTGATGTTGATAGCGGGGTAAGCGGGAGTCAGATTAG
CAAAGCATATCGCAAACTTGCCCGTAGATATCATCCAGACTCGAATCCGGGGTCTAAAGAGGCCGAGGCTCGTTTCAAAG
AAATAAGTGAAGCGTACACAGTCCTTTCCGATCCGGTACAGCGAGAGGAATATGACCAATTACGGAATCAAAAGGGCGCG
TTTACGACCGGTGATTTTGGTGATATATTCAGTAATCTCTTCACGGGCCATAGAAGCCATTTTGCCCCGTCAGGTGGTGA
TATTGCGGCTTCCGTGAAGGTATCCTTAGAATCGATTGTTCTCGGTGATTATGTGAATATGCAACTTTCTTCTGGTGAGA
CTTTAAGGGTGAAAATACCGAGTGGAATAGGTAACGGTGAACGCTTTCGTGTTAGGGGAAAAGGGGCGCCATCACCATAT
GGTGGCCCGAGCGGAGATCTCATTGTAACCGTAAATATAAGACCCCATCCTGTTTTTGAACTTGATGGAAAAGATTTGCG
CATGAATCTTCCAATAACGTTTGTTGAAGCATTTAGTGGGGCTGTTATAGAAGTTCCGACTATGCAAAAACAGACGGTAA
AGATAAAAATTCAGCCTGGTACGCTCAGTGGTATGACTCTCAGAATAAAGGGCCGTGGTGTTCAATCTGCACAACAGCCA
GGAGATCTCCTGGCTGTTGTGCAGATTGTGCCACCGAAAAATACTGATGATGTCAGAAAGATTATTGAGCAGCTTGCTGC
AAAGACTGCTGGAGATAATCCAAGACGTGATGTGCTGGAATGCGTTAGAGACTCTGACCCTTAA

Upstream 100 bases:

>100_bases
CCAGACGTTCAAACTGAGACGGTGCAGGATGTTATCGAAGCTGGATATTGCTTGGGTGAAACTGTGATCAGGGCTGCAAA
AGTTGTTGTACAGGTTCCGA

Downstream 100 bases:

>100_bases
GGTATGAAATGGGTACTCCTCAATTCTTTACTGTAACAGTAGCGGCAGCCCTATCGGGCATGCACCCACAGACACTTAGA
AAACTCGACCGCCTTGGGCT

Product: molecular chaperone DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MVSQDWLEKDFYAVLDVDSGVSGSQISKAYRKLARRYHPDSNPGSKEAEARFKEISEAYTVLSDPVQREEYDQLRNQKGA
FTTGDFGDIFSNLFTGHRSHFAPSGGDIAASVKVSLESIVLGDYVNMQLSSGETLRVKIPSGIGNGERFRVRGKGAPSPY
GGPSGDLIVTVNIRPHPVFELDGKDLRMNLPITFVEAFSGAVIEVPTMQKQTVKIKIQPGTLSGMTLRIKGRGVQSAQQP
GDLLAVVQIVPPKNTDDVRKIIEQLAAKTAGDNPRRDVLECVRDSDP

Sequences:

>Translated_287_residues
MVSQDWLEKDFYAVLDVDSGVSGSQISKAYRKLARRYHPDSNPGSKEAEARFKEISEAYTVLSDPVQREEYDQLRNQKGA
FTTGDFGDIFSNLFTGHRSHFAPSGGDIAASVKVSLESIVLGDYVNMQLSSGETLRVKIPSGIGNGERFRVRGKGAPSPY
GGPSGDLIVTVNIRPHPVFELDGKDLRMNLPITFVEAFSGAVIEVPTMQKQTVKIKIQPGTLSGMTLRIKGRGVQSAQQP
GDLLAVVQIVPPKNTDDVRKIIEQLAAKTAGDNPRRDVLECVRDSDP
>Mature_287_residues
MVSQDWLEKDFYAVLDVDSGVSGSQISKAYRKLARRYHPDSNPGSKEAEARFKEISEAYTVLSDPVQREEYDQLRNQKGA
FTTGDFGDIFSNLFTGHRSHFAPSGGDIAASVKVSLESIVLGDYVNMQLSSGETLRVKIPSGIGNGERFRVRGKGAPSPY
GGPSGDLIVTVNIRPHPVFELDGKDLRMNLPITFVEAFSGAVIEVPTMQKQTVKIKIQPGTLSGMTLRIKGRGVQSAQQP
GDLLAVVQIVPPKNTDDVRKIIEQLAAKTAGDNPRRDVLECVRDSDP

Specific function: DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adapt

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm, nucleoid [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI7706495, Length=321, Percent_Identity=28.6604361370716, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI194328760, Length=255, Percent_Identity=30.5882352941176, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI194328758, Length=255, Percent_Identity=30.5882352941176, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI6631085, Length=66, Percent_Identity=54.5454545454545, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI47777312, Length=90, Percent_Identity=48.8888888888889, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI201862518, Length=65, Percent_Identity=55.3846153846154, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI201862587, Length=65, Percent_Identity=55.3846153846154, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI56549115, Length=65, Percent_Identity=55.3846153846154, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4504511, Length=254, Percent_Identity=28.740157480315, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI5031741, Length=133, Percent_Identity=39.8496240601504, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI9558755, Length=76, Percent_Identity=51.3157894736842, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI23503241, Length=65, Percent_Identity=55.3846153846154, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4885495, Length=66, Percent_Identity=53.030303030303, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI17388799, Length=66, Percent_Identity=53.030303030303, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5453690, Length=67, Percent_Identity=53.7313432835821, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27151736, Length=64, Percent_Identity=53.125, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI88501736, Length=64, Percent_Identity=53.125, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI194306642, Length=105, Percent_Identity=40, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI194306640, Length=105, Percent_Identity=40, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI205360840, Length=65, Percent_Identity=44.6153846153846, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI205360838, Length=65, Percent_Identity=44.6153846153846, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI45504382, Length=84, Percent_Identity=39.2857142857143, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI29126218, Length=92, Percent_Identity=36.9565217391304, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787235, Length=303, Percent_Identity=39.9339933993399, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1786197, Length=141, Percent_Identity=38.2978723404255, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI212645553, Length=325, Percent_Identity=26.4615384615385, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17554644, Length=65, Percent_Identity=52.3076923076923, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17553098, Length=65, Percent_Identity=52.3076923076923, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17553096, Length=65, Percent_Identity=52.3076923076923, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534355, Length=68, Percent_Identity=50, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17507263, Length=66, Percent_Identity=48.4848484848485, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323870, Length=66, Percent_Identity=48.4848484848485, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324265, Length=268, Percent_Identity=27.9850746268657, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320888, Length=91, Percent_Identity=36.2637362637363, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19920464, Length=332, Percent_Identity=25.6024096385542, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24658562, Length=321, Percent_Identity=30.2180685358255, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24658555, Length=321, Percent_Identity=30.2180685358255, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI45549272, Length=71, Percent_Identity=49.2957746478873, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552813, Length=71, Percent_Identity=49.2957746478873, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552811, Length=71, Percent_Identity=49.2957746478873, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24654066, Length=93, Percent_Identity=40.8602150537634, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654070, Length=93, Percent_Identity=40.8602150537634, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654068, Length=93, Percent_Identity=40.8602150537634, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654072, Length=93, Percent_Identity=40.8602150537634, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651436, Length=68, Percent_Identity=48.5294117647059, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24651439, Length=68, Percent_Identity=48.5294117647059, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161077138, Length=64, Percent_Identity=53.125, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358311, Length=68, Percent_Identity=48.5294117647059, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129487, Length=119, Percent_Identity=39.4957983193277, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24584014, Length=119, Percent_Identity=39.4957983193277, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI85726398, Length=273, Percent_Identity=27.1062271062271, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24646562, Length=82, Percent_Identity=43.9024390243902, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646560, Length=82, Percent_Identity=43.9024390243902, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646558, Length=82, Percent_Identity=43.9024390243902, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646556, Length=82, Percent_Identity=43.9024390243902, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357547, Length=82, Percent_Identity=43.9024390243902, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668523, Length=84, Percent_Identity=36.9047619047619, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17737735, Length=84, Percent_Identity=36.9047619047619, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI28574723, Length=84, Percent_Identity=36.9047619047619, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C [H]

EC number: NA

Molecular weight: Translated: 31331; Mature: 31331

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSQDWLEKDFYAVLDVDSGVSGSQISKAYRKLARRYHPDSNPGSKEAEARFKEISEAYT
CCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VLSDPVQREEYDQLRNQKGAFTTGDFGDIFSNLFTGHRSHFAPSGGDIAASVKVSLESIV
HHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEHEE
LGDYVNMQLSSGETLRVKIPSGIGNGERFRVRGKGAPSPYGGPSGDLIVTVNIRPHPVFE
ECCEEEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEE
LDGKDLRMNLPITFVEAFSGAVIEVPTMQKQTVKIKIQPGTLSGMTLRIKGRGVQSAQQP
ECCCEEEEECCEEEEHHHCCCEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCC
GDLLAVVQIVPPKNTDDVRKIIEQLAAKTAGDNPRRDVLECVRDSDP
CCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MVSQDWLEKDFYAVLDVDSGVSGSQISKAYRKLARRYHPDSNPGSKEAEARFKEISEAYT
CCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VLSDPVQREEYDQLRNQKGAFTTGDFGDIFSNLFTGHRSHFAPSGGDIAASVKVSLESIV
HHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEHEE
LGDYVNMQLSSGETLRVKIPSGIGNGERFRVRGKGAPSPYGGPSGDLIVTVNIRPHPVFE
ECCEEEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEE
LDGKDLRMNLPITFVEAFSGAVIEVPTMQKQTVKIKIQPGTLSGMTLRIKGRGVQSAQQP
ECCCEEEEECCEEEEHHHCCCEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCC
GDLLAVVQIVPPKNTDDVRKIIEQLAAKTAGDNPRRDVLECVRDSDP
CCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA