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The map label for this gene is nagD [H]

Identifier: 28572895

GI number: 28572895

Start: 851640

End: 852425

Strand: Direct

Name: nagD [H]

Synonym: TW754

Alternate gene names: 28572895

Gene position: 851640-852425 (Clockwise)

Preceding gene: 28572894

Following gene: 28572897

Centisome position: 91.98

GC content: 48.73

Gene sequence:

>786_bases
TTGACCAGAAGGCAGATAAGCGCTTGGCTAACCGATATGGATGGTGTGCTCGTGAGAGGATCGCAGGCACTGTCCGGTGC
AAATAGACTGACGCGGTACTGGGCAAAAAATGATATCCCGTTTTTGGTGCTCACAAATAACTCGATATTTACACCGCGCG
ATCTTTCCGCACGTCTGAAAAGCTGTGGACTTGATGTCCCAGAACAATCAATATGGACATCCGCGATGGCTACAGCAGAA
TTTCTCAGTCAGCAGACACCTAATGGCTCTGCCTTCGTTCTGGGAGAATCGGGAATCACAACTGCAATGCATGAGGCTGG
ATACATACTCACAGACCATAATCCAGATTATGTTGTCCTGTCAGCAACGCGCACGTATTCTTTTGAGGATATATCAAAAG
CAATACGACTTATTCTTGACGGCTCTAGATTTATTACGACCAGTCCGGACCTGACAAGTCCGGGAATCGAGGGTATACAA
CTCGGAACCGGCTCGGTTGCTGCCCTAATATCTAAGGCTACAAACCGCAATCCGTATGTTGTCGGCAAGCCAAATCCAAT
GATGTTTCGCTCAGCTATGAACAGACTTGGGGCACATTCTGAAAGTACGTGCATGATAGGCGACAACATGGACACGGACA
TACTTGCCGGAATTGAAGCAGGCCTACATACAATACTTGTTTTAAGCGGGATTTGCAGCCGCGAAGACGTCCTGCGGTAT
CCGTATCGCCCTCATGAGATACTGGACGGAGTAGATGTTCTTGCCGAGCAGCTCGAGCAGGCCTAA

Upstream 100 bases:

>100_bases
CAGATTTGCCATTTGTCCGTTTGTATTGATATCTCAACTATAGAATGTATGCAAAGATAATGCCGTCCCAAGAGAATCAG
ATTGCGATAAAAGGGGGGAA

Downstream 100 bases:

>100_bases
TCTGCGGTGCCTCTGTCCAGGATATCTGTTACCCTGAGAGCTGCATAATAGGAGTACCCGGCCTTTTCTATAGCCTGTCT
TGCCCCGGTCTCGCGGTCCA

Product: N-acetylglucosamine-6-phosphate deacetylase NagD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTRRQISAWLTDMDGVLVRGSQALSGANRLTRYWAKNDIPFLVLTNNSIFTPRDLSARLKSCGLDVPEQSIWTSAMATAE
FLSQQTPNGSAFVLGESGITTAMHEAGYILTDHNPDYVVLSATRTYSFEDISKAIRLILDGSRFITTSPDLTSPGIEGIQ
LGTGSVAALISKATNRNPYVVGKPNPMMFRSAMNRLGAHSESTCMIGDNMDTDILAGIEAGLHTILVLSGICSREDVLRY
PYRPHEILDGVDVLAEQLEQA

Sequences:

>Translated_261_residues
MTRRQISAWLTDMDGVLVRGSQALSGANRLTRYWAKNDIPFLVLTNNSIFTPRDLSARLKSCGLDVPEQSIWTSAMATAE
FLSQQTPNGSAFVLGESGITTAMHEAGYILTDHNPDYVVLSATRTYSFEDISKAIRLILDGSRFITTSPDLTSPGIEGIQ
LGTGSVAALISKATNRNPYVVGKPNPMMFRSAMNRLGAHSESTCMIGDNMDTDILAGIEAGLHTILVLSGICSREDVLRY
PYRPHEILDGVDVLAEQLEQA
>Mature_260_residues
TRRQISAWLTDMDGVLVRGSQALSGANRLTRYWAKNDIPFLVLTNNSIFTPRDLSARLKSCGLDVPEQSIWTSAMATAEF
LSQQTPNGSAFVLGESGITTAMHEAGYILTDHNPDYVVLSATRTYSFEDISKAIRLILDGSRFITTSPDLTSPGIEGIQL
GTGSVAALISKATNRNPYVVGKPNPMMFRSAMNRLGAHSESTCMIGDNMDTDILAGIEAGLHTILVLSGICSREDVLRYP
YRPHEILDGVDVLAEQLEQA

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10092677, Length=274, Percent_Identity=29.9270072992701, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI108796653, Length=262, Percent_Identity=28.2442748091603, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI14149777, Length=233, Percent_Identity=26.6094420600858, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI269847098, Length=219, Percent_Identity=24.6575342465753, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786890, Length=242, Percent_Identity=41.3223140495868, Blast_Score=199, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17562458, Length=266, Percent_Identity=26.6917293233083, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17558880, Length=266, Percent_Identity=26.6917293233083, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560956, Length=266, Percent_Identity=26.6917293233083, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562356, Length=262, Percent_Identity=28.6259541984733, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193210059, Length=262, Percent_Identity=25.9541984732824, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17557870, Length=255, Percent_Identity=24.3137254901961, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI86563050, Length=245, Percent_Identity=26.9387755102041, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319965, Length=238, Percent_Identity=26.890756302521, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24666141, Length=269, Percent_Identity=29.7397769516729, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24656326, Length=267, Percent_Identity=26.2172284644195, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24656330, Length=270, Percent_Identity=25.5555555555556, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI22026920, Length=255, Percent_Identity=25.4901960784314, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI18859765, Length=282, Percent_Identity=25.886524822695, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920940, Length=228, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 28413; Mature: 28281

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRQISAWLTDMDGVLVRGSQALSGANRLTRYWAKNDIPFLVLTNNSIFTPRDLSARLK
CCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
SCGLDVPEQSIWTSAMATAEFLSQQTPNGSAFVLGESGITTAMHEAGYILTDHNPDYVVL
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCEEEECCCCCEEEE
SATRTYSFEDISKAIRLILDGSRFITTSPDLTSPGIEGIQLGTGSVAALISKATNRNPYV
EECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCEE
VGKPNPMMFRSAMNRLGAHSESTCMIGDNMDTDILAGIEAGLHTILVLSGICSREDVLRY
EECCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
PYRPHEILDGVDVLAEQLEQA
CCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRRQISAWLTDMDGVLVRGSQALSGANRLTRYWAKNDIPFLVLTNNSIFTPRDLSARLK
CHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
SCGLDVPEQSIWTSAMATAEFLSQQTPNGSAFVLGESGITTAMHEAGYILTDHNPDYVVL
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCEEEECCCCCEEEE
SATRTYSFEDISKAIRLILDGSRFITTSPDLTSPGIEGIQLGTGSVAALISKATNRNPYV
EECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCEE
VGKPNPMMFRSAMNRLGAHSESTCMIGDNMDTDILAGIEAGLHTILVLSGICSREDVLRY
EECCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
PYRPHEILDGVDVLAEQLEQA
CCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]