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The map label for this gene is php [C]

Identifier: 28572813

GI number: 28572813

Start: 763248

End: 764228

Strand: Reverse

Name: php [C]

Synonym: TW672

Alternate gene names: 28572813

Gene position: 764228-763248 (Counterclockwise)

Preceding gene: 28572814

Following gene: 28572812

Centisome position: 82.54

GC content: 46.28

Gene sequence:

>981_bases
TTGGGATTTGTAAGGACGATAAAGGGTGACGTTTCGCCCGATTTACTTGGGTGTGTTAATTGCCACGATCATTTGATTCG
TACCGGCGCCGGTGAGGTGTATTTAGACAAGGATCATTTGCTGGACAGTGTCGACAAGGCAGTTGAAGAGGCGAGTTATT
TCGTTCAGGCTAGTAAGCGTTGGTCTCAGACGGCAACAATTATTGATATGTGTCCCGCCGATTGTGGGCGTGATGTCCTA
AAACTTGTCGAGGTAAACAATCGGATTCCGGGACTTCATATAGTTGTAGCAACAGGCTTCCACCGCGAACACGTTTATCT
AGAAACAAAATGCCACTGGGTGAGTCGCTATTCTGTGAACCAGATAGCTGATCTTCTTATAGCTGATATTGAAGAGGGAG
TGGATGCCCATGACTATTCTGGACCAATTGTAGAAAGAACCCCTTATAAGGCTGGGGTTATAAAGTTTGCTTCTGCTTAT
GGCCAGATTACTGAATGGGAGAAAAAGACCCAGGAAGCTGTGGCGATAGCTGCGAAGGTTACCGGTGCACCGATCAACAC
ACATACAACTTTTGGCACAGCCGGTCTTGAACAGGCAAAGCGGTTTATTGAATTGGGTGTTGATCCAGATCAGGTTGCTA
TAGGCCATATACAGCGAAATGCTGATGTGTACTATCTAGCACAGATACTAAAACTTGGCGTTTATCTCGAGCTTGATGGG
ACGTATAGGATCAAATATCTCCCTGATAGTGCACGGGTAACGCTTGTGCGTGAACTTGGCAAGCAGGGTTTTGGCAAGCG
ACTCTTGCTCGGTACCGATTCTGGAAAGCGGAGTTATCAAAAGGCTTACGGTGCGGTGAGTGGCATTGATTACGATCCTT
CAGTATTCGCCCCTCGACTGCTGGATGAAGGTTTTGATCCTGATTATGTTGATGATCTGCTTATGTACAATGCACAAACT
TTCTTTCAGGTCAGGCGGTAA

Upstream 100 bases:

>100_bases
TGTTCCTGCTGGATTTTCTGCGTGCGGCATACTTTCACAGCACTTCATGCCAGGTTTTTCGTAATGGTTCGATTTTACGT
AGTTTCCCATGGAGGTTGTT

Downstream 100 bases:

>100_bases
TGACTCGCGCTGTTATAGAACATCCCTCGCGGCCGCTTCTTCAGGTTGCACTCGATACATTTGACCTTTCAAGCGCCCTG
GGGCCTCTGCAAAAATCTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MGFVRTIKGDVSPDLLGCVNCHDHLIRTGAGEVYLDKDHLLDSVDKAVEEASYFVQASKRWSQTATIIDMCPADCGRDVL
KLVEVNNRIPGLHIVVATGFHREHVYLETKCHWVSRYSVNQIADLLIADIEEGVDAHDYSGPIVERTPYKAGVIKFASAY
GQITEWEKKTQEAVAIAAKVTGAPINTHTTFGTAGLEQAKRFIELGVDPDQVAIGHIQRNADVYYLAQILKLGVYLELDG
TYRIKYLPDSARVTLVRELGKQGFGKRLLLGTDSGKRSYQKAYGAVSGIDYDPSVFAPRLLDEGFDPDYVDDLLMYNAQT
FFQVRR

Sequences:

>Translated_326_residues
MGFVRTIKGDVSPDLLGCVNCHDHLIRTGAGEVYLDKDHLLDSVDKAVEEASYFVQASKRWSQTATIIDMCPADCGRDVL
KLVEVNNRIPGLHIVVATGFHREHVYLETKCHWVSRYSVNQIADLLIADIEEGVDAHDYSGPIVERTPYKAGVIKFASAY
GQITEWEKKTQEAVAIAAKVTGAPINTHTTFGTAGLEQAKRFIELGVDPDQVAIGHIQRNADVYYLAQILKLGVYLELDG
TYRIKYLPDSARVTLVRELGKQGFGKRLLLGTDSGKRSYQKAYGAVSGIDYDPSVFAPRLLDEGFDPDYVDDLLMYNAQT
FFQVRR
>Mature_325_residues
GFVRTIKGDVSPDLLGCVNCHDHLIRTGAGEVYLDKDHLLDSVDKAVEEASYFVQASKRWSQTATIIDMCPADCGRDVLK
LVEVNNRIPGLHIVVATGFHREHVYLETKCHWVSRYSVNQIADLLIADIEEGVDAHDYSGPIVERTPYKAGVIKFASAYG
QITEWEKKTQEAVAIAAKVTGAPINTHTTFGTAGLEQAKRFIELGVDPDQVAIGHIQRNADVYYLAQILKLGVYLELDGT
YRIKYLPDSARVTLVRELGKQGFGKRLLLGTDSGKRSYQKAYGAVSGIDYDPSVFAPRLLDEGFDPDYVDDLLMYNAQTF
FQVRR

Specific function: Its Real Enzymatic Activity Is Not Yet Known. It Was Tested For General Esterase, Aminopeptidase, Sulfatase, Phosphatase, Carbonic Anhydrase, Phosphodiesterase, And Phosphotriesterase Activities With The Following Substrates: P- Nitrophenyl Acetate, L-Ala

COG id: COG1735

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphotriesterase family [H]

Homologues:

Organism=Homo sapiens, GI20070186, Length=365, Percent_Identity=24.1095890410959, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI47933341, Length=365, Percent_Identity=24.1095890410959, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789780, Length=316, Percent_Identity=30.0632911392405, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001559 [H]

Pfam domain/function: PF02126 PTE [H]

EC number: NA

Molecular weight: Translated: 36293; Mature: 36161

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS01323 PHOSPHOTRIESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFVRTIKGDVSPDLLGCVNCHDHLIRTGAGEVYLDKDHLLDSVDKAVEEASYFVQASKR
CCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
WSQTATIIDMCPADCGRDVLKLVEVNNRIPGLHIVVATGFHREHVYLETKCHWVSRYSVN
HHHHHHHEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEEEEEEHHCCHH
QIADLLIADIEEGVDAHDYSGPIVERTPYKAGVIKFASAYGQITEWEKKTQEAVAIAAKV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
TGAPINTHTTFGTAGLEQAKRFIELGVDPDQVAIGHIQRNADVYYLAQILKLGVYLELDG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHCCCCCHHHHHHHHHCCEEEEECC
TYRIKYLPDSARVTLVRELGKQGFGKRLLLGTDSGKRSYQKAYGAVSGIDYDPSVFAPRL
EEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHH
LDEGFDPDYVDDLLMYNAQTFFQVRR
HHCCCCCHHHHHHHHHCCHHHHEECC
>Mature Secondary Structure 
GFVRTIKGDVSPDLLGCVNCHDHLIRTGAGEVYLDKDHLLDSVDKAVEEASYFVQASKR
CCCEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
WSQTATIIDMCPADCGRDVLKLVEVNNRIPGLHIVVATGFHREHVYLETKCHWVSRYSVN
HHHHHHHEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEEEEEEHHCCHH
QIADLLIADIEEGVDAHDYSGPIVERTPYKAGVIKFASAYGQITEWEKKTQEAVAIAAKV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
TGAPINTHTTFGTAGLEQAKRFIELGVDPDQVAIGHIQRNADVYYLAQILKLGVYLELDG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHCCCCCHHHHHHHHHCCEEEEECC
TYRIKYLPDSARVTLVRELGKQGFGKRLLLGTDSGKRSYQKAYGAVSGIDYDPSVFAPRL
EEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHH
LDEGFDPDYVDDLLMYNAQTFFQVRR
HHCCCCCHHHHHHHHHCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]