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The map label for this gene is nrdR

Identifier: 28572682

GI number: 28572682

Start: 571543

End: 571986

Strand: Reverse

Name: nrdR

Synonym: TW533

Alternate gene names: 28572682

Gene position: 571986-571543 (Counterclockwise)

Preceding gene: 28572683

Following gene: 28572681

Centisome position: 61.77

GC content: 47.3

Gene sequence:

>444_bases
ATGCGCTGTCTGTTTTGCCGGTCTGATGATACAAAGGTTATAGATTCCAGGACATCTGAGGACGGCATAAGCATAAGGCG
TCGCCGTGAATGCCAGTTGTGTAAGAGGCGTTTTAGCACCCTTGAAACTGCAAGTCTTACCGTTATAAAGCGAAATGGAA
CCTCCGAGCCATTTAGGAGGGAGAAGGTTGTAACAGGGGTGCATAAGGCCTGCCAGGGTCGCCCTGTAACAAAGGCTGAT
CTTGCCGTTTTAGCTCAGAGGGTTGAAGAGAGCCTGCGTGCATCGGGTAATAGTCAGGTTGATTCCAATGATATCGGTCT
TGCAATACTCCCTGAGCTTTTGAGGCTTGACCAGGTTGCCTACATAAGGTTTGCTAGTGTATATCAAGATTTTGACTCTC
TGGAAGATTTTTCCAGGGCTGTAGAGAGGCTGAAAAATCAGTAA

Upstream 100 bases:

>100_bases
TGGAATTGCCGTTGGCAAGGTTCTTCGCGAAATAGAGGATACTTTGACCGGTATTGAGTCTCGCGAGATGAATGCCGAGA
GAAAGTATCTTTTATTGTAG

Downstream 100 bases:

>100_bases
GATCGAGTGTATTCATATTTTTTGAATTTTCTAAAGTGTGTGGATCCAGAACTGGCACACAGAATTGCCGCGGTTGCTCT
AAAGTCTGGATTGGGCATGT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MRCLFCRSDDTKVIDSRTSEDGISIRRRRECQLCKRRFSTLETASLTVIKRNGTSEPFRREKVVTGVHKACQGRPVTKAD
LAVLAQRVEESLRASGNSQVDSNDIGLAILPELLRLDQVAYIRFASVYQDFDSLEDFSRAVERLKNQ

Sequences:

>Translated_147_residues
MRCLFCRSDDTKVIDSRTSEDGISIRRRRECQLCKRRFSTLETASLTVIKRNGTSEPFRREKVVTGVHKACQGRPVTKAD
LAVLAQRVEESLRASGNSQVDSNDIGLAILPELLRLDQVAYIRFASVYQDFDSLEDFSRAVERLKNQ
>Mature_147_residues
MRCLFCRSDDTKVIDSRTSEDGISIRRRRECQLCKRRFSTLETASLTVIKRNGTSEPFRREKVVTGVHKACQGRPVTKAD
LAVLAQRVEESLRASGNSQVDSNDIGLAILPELLRLDQVAYIRFASVYQDFDSLEDFSRAVERLKNQ

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=43.6241610738255, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_TROW8 (P67324)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789462.1
- STRING:   P67324
- GeneID:   1064737
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW533
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   P67324
- ProtClustDB:   PRK00464
- BioCyc:   TWHI218496:TW0507-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 16725; Mature: 16725

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCLFCRSDDTKVIDSRTSEDGISIRRRRECQLCKRRFSTLETASLTVIKRNGTSEPFRR
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHH
EKVVTGVHKACQGRPVTKADLAVLAQRVEESLRASGNSQVDSNDIGLAILPELLRLDQVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
YIRFASVYQDFDSLEDFSRAVERLKNQ
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRCLFCRSDDTKVIDSRTSEDGISIRRRRECQLCKRRFSTLETASLTVIKRNGTSEPFRR
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHH
EKVVTGVHKACQGRPVTKADLAVLAQRVEESLRASGNSQVDSNDIGLAILPELLRLDQVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
YIRFASVYQDFDSLEDFSRAVERLKNQ
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12606174