| Definition | Tropheryma whipplei TW08/27, complete genome. |
|---|---|
| Accession | NC_004551 |
| Length | 925,938 |
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The map label for this gene is fabG [H]
Identifier: 28572609
GI number: 28572609
Start: 496060
End: 496776
Strand: Reverse
Name: fabG [H]
Synonym: TW459
Alternate gene names: 28572609
Gene position: 496776-496060 (Counterclockwise)
Preceding gene: 28572610
Following gene: 28572608
Centisome position: 53.65
GC content: 44.77
Gene sequence:
>717_bases ATGTCTAGCAAGAGAACAGTTTTTATAACCGGGGGAAACCGGGGGATAGGTCGCGCAATTGCTGAAAAGTTCAAGAGCTT CAACTACAATGTCGCGATTGGAGTAAGGCAACCTGAAGCTTTCAAGGATGCTGGCTGCCTTGCAGTTGAGTGCGATGTAA CCGTCTCTAGCTCGCTTACAAAAGCTTTCAAAGAGGTAGAAGAGAGATTCGGTTTTGTTGATGTGGCGATTGCAAATGCT GGAATTATCAGGGACACACTTGTTCTACGGATGAAAGAGGATGATTTTCAACATATCCTTGATACCAATCTGACAGGCGC GTGGAGGCTTGCCAAACTTGCGAGTAGATCGATGATGCGAAATAAGTTTGGTCGCATAGTTTTTATATCAAGTGTTTCTG CTGGGATGGGTGGTATTGGTCAGACAAATTATTCAGCATCTAAGGCTGGAATGATAGGCCTTGCTAGAGCTTTAACCCGT GAGCTTGCAAGTTTTGGCATTACTGTGAATGTTGTAGCTCCCGGAATAGTGCAGACGGATATGGTATCGTCAATCCCTGA CAATTTGAGAGAGGAATTGATACAAAGGGTGCCAATACGTCGAATTGGTCTGCCAGAGGAAGTTGCTAATGCCGTTTTTT GGCTTTCCAGTGATGAGGCAAGTTATGTATCCGGAGTTGTATTGCCTGTGGACGGTGGCTTATCAATGGGTTTTTAA
Upstream 100 bases:
>100_bases ACGCAGGTCCTTGGAAATTGTTGCGGAACACGAAATAGACCGCACAATAGATGCGTTTGAGCGGCTGTATGCAGGCTCTC AAGTATCCTGCAACTAGTCT
Downstream 100 bases:
>100_bases CCCCCGCGGGTTGCAGAATCCTGTCCGTCCTGCTTTCTGTGTCACATGCAGTTCAAGCAGTTTTTATTTCTCGCTTCAGA ATATTCTGTGTTTAGACTAG
Product: 3-oxoacyl-[acyl-carrier protein] reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 238; Mature: 237
Protein sequence:
>238_residues MSSKRTVFITGGNRGIGRAIAEKFKSFNYNVAIGVRQPEAFKDAGCLAVECDVTVSSSLTKAFKEVEERFGFVDVAIANA GIIRDTLVLRMKEDDFQHILDTNLTGAWRLAKLASRSMMRNKFGRIVFISSVSAGMGGIGQTNYSASKAGMIGLARALTR ELASFGITVNVVAPGIVQTDMVSSIPDNLREELIQRVPIRRIGLPEEVANAVFWLSSDEASYVSGVVLPVDGGLSMGF
Sequences:
>Translated_238_residues MSSKRTVFITGGNRGIGRAIAEKFKSFNYNVAIGVRQPEAFKDAGCLAVECDVTVSSSLTKAFKEVEERFGFVDVAIANA GIIRDTLVLRMKEDDFQHILDTNLTGAWRLAKLASRSMMRNKFGRIVFISSVSAGMGGIGQTNYSASKAGMIGLARALTR ELASFGITVNVVAPGIVQTDMVSSIPDNLREELIQRVPIRRIGLPEEVANAVFWLSSDEASYVSGVVLPVDGGLSMGF >Mature_237_residues SSKRTVFITGGNRGIGRAIAEKFKSFNYNVAIGVRQPEAFKDAGCLAVECDVTVSSSLTKAFKEVEERFGFVDVAIANAG IIRDTLVLRMKEDDFQHILDTNLTGAWRLAKLASRSMMRNKFGRIVFISSVSAGMGGIGQTNYSASKAGMIGLARALTRE LASFGITVNVVAPGIVQTDMVSSIPDNLREELIQRVPIRRIGLPEEVANAVFWLSSDEASYVSGVVLPVDGGLSMGF
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=40.5982905982906, Blast_Score=158, Evalue=4e-39, Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=31.5789473684211, Blast_Score=132, Evalue=2e-31, Organism=Homo sapiens, GI4758504, Length=248, Percent_Identity=32.258064516129, Blast_Score=110, Evalue=8e-25, Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=28.8, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI4504505, Length=238, Percent_Identity=30.672268907563, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI83715985, Length=248, Percent_Identity=30.241935483871, Blast_Score=94, Evalue=8e-20, Organism=Homo sapiens, GI59889578, Length=204, Percent_Identity=30.3921568627451, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=29.6875, Blast_Score=87, Evalue=9e-18, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=28.3400809716599, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=27.0161290322581, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=30.6451612903226, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI31542939, Length=252, Percent_Identity=27.3809523809524, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI7705925, Length=237, Percent_Identity=27.0042194092827, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI4503301, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=27.2, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI20149619, Length=190, Percent_Identity=26.8421052631579, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503817, Length=223, Percent_Identity=26.457399103139, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=30.4123711340206, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI7657478, Length=192, Percent_Identity=30.7291666666667, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI50726952, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=43.5146443514644, Blast_Score=198, Evalue=3e-52, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=35.3413654618474, Blast_Score=143, Evalue=9e-36, Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=32.5102880658436, Blast_Score=120, Evalue=6e-29, Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=36.2869198312236, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=31.8181818181818, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=29.045643153527, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=29.6296296296296, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1789208, Length=239, Percent_Identity=27.1966527196653, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=31.3807531380753, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789057, Length=198, Percent_Identity=32.3232323232323, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=28.4, Blast_Score=80, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=34.4262295081967, Blast_Score=145, Evalue=2e-35, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=33.0645161290323, Blast_Score=142, Evalue=2e-34, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=30.8943089430894, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=28.3400809716599, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17538182, Length=246, Percent_Identity=28.8617886178862, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=31.3253012048193, Blast_Score=93, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=28.4, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17536025, Length=246, Percent_Identity=26.8292682926829, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17568967, Length=138, Percent_Identity=35.5072463768116, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=28.1632653061224, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=29.277566539924, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17561272, Length=234, Percent_Identity=26.4957264957265, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=27.0491803278689, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=25.2918287937743, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=27.3764258555133, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=26.2357414448669, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=26.5384615384615, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=28.8973384030418, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=25.8555133079848, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=27.7566539923954, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17507613, Length=200, Percent_Identity=30.5, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI32563809, Length=200, Percent_Identity=30.5, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17567345, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=27.7566539923954, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=27.9693486590038, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=25.3886010362694, Blast_Score=68, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=22.9838709677419, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=24.6153846153846, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=25.6704980842912, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=24.5283018867925, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=23.6842105263158, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=247, Percent_Identity=31.5789473684211, Blast_Score=108, Evalue=1e-24, Organism=Saccharomyces cerevisiae, GI6324126, Length=245, Percent_Identity=28.9795918367347, Blast_Score=96, Evalue=6e-21, Organism=Saccharomyces cerevisiae, GI6320089, Length=197, Percent_Identity=26.9035532994924, Blast_Score=77, Evalue=2e-15, Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=5e-37, Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=31.4516129032258, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI17737361, Length=248, Percent_Identity=29.8387096774194, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=29.0983606557377, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=30.8641975308642, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=28.6852589641434, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=26.9387755102041, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI18859837, Length=239, Percent_Identity=29.2887029288703, Blast_Score=84, Evalue=6e-17, Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=30.5555555555556, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=28.1632653061224, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=32.5842696629214, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI116007236, Length=233, Percent_Identity=28.3261802575107, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI28571387, Length=245, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24581726, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24656154, Length=232, Percent_Identity=28.0172413793103, Blast_Score=64, Evalue=9e-11, Organism=Drosophila melanogaster, GI19922628, Length=232, Percent_Identity=28.0172413793103, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25660; Mature: 25529
Theoretical pI: Translated: 9.18; Mature: 9.18
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.4 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSKRTVFITGGNRGIGRAIAEKFKSFNYNVAIGVRQPEAFKDAGCLAVECDVTVSSSLT CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCEEEEECCCHHHHHH KAFKEVEERFGFVDVAIANAGIIRDTLVLRMKEDDFQHILDTNLTGAWRLAKLASRSMMR HHHHHHHHHCCEEEEEECCCCHHHHHEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHH NKFGRIVFISSVSAGMGGIGQTNYSASKAGMIGLARALTRELASFGITVNVVAPGIVQTD HHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHH MVSSIPDNLREELIQRVPIRRIGLPEEVANAVFWLSSDEASYVSGVVLPVDGGLSMGF HHHHCCHHHHHHHHHHCCHHHCCCHHHHHHEEEEECCCCCHHHCEEEEEECCCCCCCC >Mature Secondary Structure SSKRTVFITGGNRGIGRAIAEKFKSFNYNVAIGVRQPEAFKDAGCLAVECDVTVSSSLT CCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCEEEEECCCHHHHHH KAFKEVEERFGFVDVAIANAGIIRDTLVLRMKEDDFQHILDTNLTGAWRLAKLASRSMMR HHHHHHHHHCCEEEEEECCCCHHHHHEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHH NKFGRIVFISSVSAGMGGIGQTNYSASKAGMIGLARALTRELASFGITVNVVAPGIVQTD HHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHH MVSSIPDNLREELIQRVPIRRIGLPEEVANAVFWLSSDEASYVSGVVLPVDGGLSMGF HHHHCCHHHHHHHHHHCCHHHCCCHHHHHHEEEEECCCCCHHHCEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA