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The map label for this gene is pyrF [H]

Identifier: 28572558

GI number: 28572558

Start: 443180

End: 444091

Strand: Direct

Name: pyrF [H]

Synonym: TW405

Alternate gene names: 28572558

Gene position: 443180-444091 (Clockwise)

Preceding gene: 28572557

Following gene: 28572559

Centisome position: 47.86

GC content: 46.38

Gene sequence:

>912_bases
ATGATCTCTTTCGGAGATAGATTGCAGAATGCCTTCACTGATTTTGGGCATCTGTGTGTCGGAATAGATCCACATGAGTG
GATTTTGGAGCAGTGGGGGCTTCCAAACTCTCCCGCTGGTGCGCAAGAGTTTGCCCTTAGGATACTTGACTTATCCTCTG
AGCATGTTGGCCTCTATAAGGTACAGGTTGCTTTTTACGAAAGATTTGGCTCGAAGGGGATTTTTGCGCTTGAGGAGGTA
ATATCCGCAATTCGCTCAACCGGCGCTCTTGTGATAGCCGATGGAAAAAGGGGGGATATTTCATCGACAATGTCAGGATA
CGCAAAGGCTTGGTTGTGTAGGGATTCACGGCTCTTTAGTGATGCCCTGACTGTATCTCCTTATGTTGGTCTTGGCAGTT
TTAAGGGTAGCATTGATATCGCAAGACAAAATGGCGCAGGCTTGTTTTTTCTCGCGGCAACTTCCGAGATGCATGCATTT
CCGATACAGAGTGCAATTCTGCAAGATCGCCAGGGAACTTTTGGTGAGTCCTCTGGAAGCATATTGTCATGTTCCGATAT
AACCGTTGCGTCATACATTTTTGAGAGTATCGGGACTCTTGTAGGTAATCCCTCTGATTGTTCCAGTTTTGGAGTTGTTT
TGTCTGCCACAAGCGATCTTTTATCTCTGGGGATTGGTTGCAATCTCTCTGAGTTTTCAAGGGTTATGCCAATTCTTGCA
CCGGGCTTTGGTTACCAAGGGGTAGAGCTTAAGGATTCCCGAAAACGATTTGGCAGTCTTATCTCTAATTTGATAATAAG
TGAATCTCGCAGTCTGCTTGCCTCAGGCCCCAGGCGGTTTTCTGCACTTGTGAATACTCGCTCCGAAGAGCTAAGATCGC
TTTTTGACGATTCGCACGAGAATGCTGGTTAG

Upstream 100 bases:

>100_bases
TGAACGCTGCAGTTATAAGTCTTGAGTCGGGTTCGCACGAAATCGCGAGTTTGCAGGAGCTATATTCTAGCCGCGCGCGT
TCAGCTGAAAATCTCTGCGG

Downstream 100 bases:

>100_bases
GAAGGTTATTGGCGATATATGAGACGCCCTCCTCCAAAACCCGACTGGCAGTCGGCATCAAAAAAAGGGGTTGAAGTGCG
GAAGATCCGTGCAGAAGTGA

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MISFGDRLQNAFTDFGHLCVGIDPHEWILEQWGLPNSPAGAQEFALRILDLSSEHVGLYKVQVAFYERFGSKGIFALEEV
ISAIRSTGALVIADGKRGDISSTMSGYAKAWLCRDSRLFSDALTVSPYVGLGSFKGSIDIARQNGAGLFFLAATSEMHAF
PIQSAILQDRQGTFGESSGSILSCSDITVASYIFESIGTLVGNPSDCSSFGVVLSATSDLLSLGIGCNLSEFSRVMPILA
PGFGYQGVELKDSRKRFGSLISNLIISESRSLLASGPRRFSALVNTRSEELRSLFDDSHENAG

Sequences:

>Translated_303_residues
MISFGDRLQNAFTDFGHLCVGIDPHEWILEQWGLPNSPAGAQEFALRILDLSSEHVGLYKVQVAFYERFGSKGIFALEEV
ISAIRSTGALVIADGKRGDISSTMSGYAKAWLCRDSRLFSDALTVSPYVGLGSFKGSIDIARQNGAGLFFLAATSEMHAF
PIQSAILQDRQGTFGESSGSILSCSDITVASYIFESIGTLVGNPSDCSSFGVVLSATSDLLSLGIGCNLSEFSRVMPILA
PGFGYQGVELKDSRKRFGSLISNLIISESRSLLASGPRRFSALVNTRSEELRSLFDDSHENAG
>Mature_303_residues
MISFGDRLQNAFTDFGHLCVGIDPHEWILEQWGLPNSPAGAQEFALRILDLSSEHVGLYKVQVAFYERFGSKGIFALEEV
ISAIRSTGALVIADGKRGDISSTMSGYAKAWLCRDSRLFSDALTVSPYVGLGSFKGSIDIARQNGAGLFFLAATSEMHAF
PIQSAILQDRQGTFGESSGSILSCSDITVASYIFESIGTLVGNPSDCSSFGVVLSATSDLLSLGIGCNLSEFSRVMPILA
PGFGYQGVELKDSRKRFGSLISNLIISESRSLLASGPRRFSALVNTRSEELRSLFDDSHENAG

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR018089
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 32566; Mature: 32566

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFGDRLQNAFTDFGHLCVGIDPHEWILEQWGLPNSPAGAQEFALRILDLSSEHVGLYK
CCCCHHHHHHHHHHHCCEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEE
VQVAFYERFGSKGIFALEEVISAIRSTGALVIADGKRGDISSTMSGYAKAWLCRDSRLFS
EHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHH
DALTVSPYVGLGSFKGSIDIARQNGAGLFFLAATSEMHAFPIQSAILQDRQGTFGESSGS
HHHCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCC
ILSCSDITVASYIFESIGTLVGNPSDCSSFGVVLSATSDLLSLGIGCNLSEFSRVMPILA
EEEECCHHHHHHHHHHHHHHCCCCCCHHHHCCCEECHHHHHHHCCCCCHHHHHHHHHHHC
PGFGYQGVELKDSRKRFGSLISNLIISESRSLLASGPRRFSALVNTRSEELRSLFDDSHE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHCCHHHHHHHHCCCCC
NAG
CCC
>Mature Secondary Structure
MISFGDRLQNAFTDFGHLCVGIDPHEWILEQWGLPNSPAGAQEFALRILDLSSEHVGLYK
CCCCHHHHHHHHHHHCCEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEE
VQVAFYERFGSKGIFALEEVISAIRSTGALVIADGKRGDISSTMSGYAKAWLCRDSRLFS
EHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHH
DALTVSPYVGLGSFKGSIDIARQNGAGLFFLAATSEMHAFPIQSAILQDRQGTFGESSGS
HHHCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCC
ILSCSDITVASYIFESIGTLVGNPSDCSSFGVVLSATSDLLSLGIGCNLSEFSRVMPILA
EEEECCHHHHHHHHHHHHHHCCCCCCHHHHCCCEECHHHHHHHCCCCCHHHHHHHHHHHC
PGFGYQGVELKDSRKRFGSLISNLIISESRSLLASGPRRFSALVNTRSEELRSLFDDSHE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHCCHHHHHHHHCCCCC
NAG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]