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The map label for this gene is efp

Identifier: 28572554

GI number: 28572554

Start: 436842

End: 437399

Strand: Direct

Name: efp

Synonym: TW401

Alternate gene names: 28572554

Gene position: 436842-437399 (Clockwise)

Preceding gene: 28572553

Following gene: 28572555

Centisome position: 47.18

GC content: 44.8

Gene sequence:

>558_bases
GTGGCGTCAACTTCCGATATCCGTAATGGTGTTGTTCTCAATATAAATGGGCAACTGAATACAGTGATCGAGTTTCAGCA
TGTAAAGCCCGGGAAGGGTGGCGCATTTGTTAGGACAAAACTGAAAAATATTCTGACTGGAAAGGTTGTTGATAAAACAT
TTAATGCAGGTGCCAGCGTTGTTCTTGAGAATGTTGATAGGCGTGATTGCACCTATCTGTATCGTGATGCTGATAGTTTC
GTGTTTATGGATCTTGCTGATTACGATCAGATACGCCTAACTGCCTCTCAGGTTGCTTCTGCTGCAAACTATCTTTCCGA
TAATCAGAAAGTTGTTATCGCGACACATAATAATGCGCCTCTGTATGTTGATTTGCCTCCGTCTGTTGTGCTTGCAGTTA
CGCATACAGAACCTGGCGTTCAGGCGGACCGTTCAACAGGTGGAACTAAACCTGCAACCCTTGAGACTGGTTATCAGATT
CAGGTTCCACTCTTTATTACTGTCGGGACTCGTATAAGAGTCGATACCCGCACGGGGGCATATATCGGCAAAGCATGA

Upstream 100 bases:

>100_bases
CGCACAGGTTTCAGGGCTGGGGGTTGATTCGTATAGACTTGCCCTTGACCATATCGTACGAAAGATAGCATGTTAGGTGT
TGGACATTTGAAAGGGGATT

Downstream 100 bases:

>100_bases
GGATATTAAATTGTGACCCGCCAATCTTTTTTTATAAAAAATGTAACACTGCCAGGGCTTGGCGCGAGAACATTGTTTTT
GTCTGGTGGTCTTATCCAGG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MASTSDIRNGVVLNINGQLNTVIEFQHVKPGKGGAFVRTKLKNILTGKVVDKTFNAGASVVLENVDRRDCTYLYRDADSF
VFMDLADYDQIRLTASQVASAANYLSDNQKVVIATHNNAPLYVDLPPSVVLAVTHTEPGVQADRSTGGTKPATLETGYQI
QVPLFITVGTRIRVDTRTGAYIGKA

Sequences:

>Translated_185_residues
MASTSDIRNGVVLNINGQLNTVIEFQHVKPGKGGAFVRTKLKNILTGKVVDKTFNAGASVVLENVDRRDCTYLYRDADSF
VFMDLADYDQIRLTASQVASAANYLSDNQKVVIATHNNAPLYVDLPPSVVLAVTHTEPGVQADRSTGGTKPATLETGYQI
QVPLFITVGTRIRVDTRTGAYIGKA
>Mature_184_residues
ASTSDIRNGVVLNINGQLNTVIEFQHVKPGKGGAFVRTKLKNILTGKVVDKTFNAGASVVLENVDRRDCTYLYRDADSFV
FMDLADYDQIRLTASQVASAANYLSDNQKVVIATHNNAPLYVDLPPSVVLAVTHTEPGVQADRSTGGTKPATLETGYQIQ
VPLFITVGTRIRVDTRTGAYIGKA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=181, Percent_Identity=37.0165745856354, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=4e-21,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_TROW8 (Q83NK8)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789334.1
- ProteinModelPortal:   Q83NK8
- SMR:   Q83NK8
- STRING:   Q83NK8
- GeneID:   1064245
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW401
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q83NK8
- ProtClustDB:   PRK00529
- BioCyc:   TWHI218496:TW0379-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20016; Mature: 19885

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTSDIRNGVVLNINGQLNTVIEFQHVKPGKGGAFVRTKLKNILTGKVVDKTFNAGASV
CCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCEECCCCCCCCEE
VLENVDRRDCTYLYRDADSFVFMDLADYDQIRLTASQVASAANYLSDNQKVVIATHNNAP
EEECCCCCCCEEEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCCEEEEEECCCCC
LYVDLPPSVVLAVTHTEPGVQADRSTGGTKPATLETGYQIQVPLFITVGTRIRVDTRTGA
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEEEECCEEEEECCCCE
YIGKA
EEECC
>Mature Secondary Structure 
ASTSDIRNGVVLNINGQLNTVIEFQHVKPGKGGAFVRTKLKNILTGKVVDKTFNAGASV
CCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCEECCCCCCCCEE
VLENVDRRDCTYLYRDADSFVFMDLADYDQIRLTASQVASAANYLSDNQKVVIATHNNAP
EEECCCCCCCEEEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCCEEEEEECCCCC
LYVDLPPSVVLAVTHTEPGVQADRSTGGTKPATLETGYQIQVPLFITVGTRIRVDTRTGA
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEEEECCEEEEECCCCE
YIGKA
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12606174