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The map label for this gene is coaA [H]

Identifier: 28572319

GI number: 28572319

Start: 180517

End: 181272

Strand: Reverse

Name: coaA [H]

Synonym: TW156

Alternate gene names: 28572319

Gene position: 181272-180517 (Counterclockwise)

Preceding gene: 28572322

Following gene: 28572315

Centisome position: 19.58

GC content: 38.36

Gene sequence:

>756_bases
TTGGGAATTGAAGTGTTCAAGAAAGATATAACAAAAACGTATACCGAAATGCTAAAGGATATACGAAAGAGGGTTAGGGA
AAGAGGAAAGGTTGGCAAAAGTTTTATCATTGGCATAACAGGTTCTGTTGCTGCTGGTAAATCTACACTCGCAAGCGATC
TAGCCAAAATGTTGGATGGGATAAGTGTTGAGGTTATATCAACTGACGGATATTTGTATCCAAATAAAATCCTGGAGCAA
AAGGGGCTGATGCTTAAAAAGGGATTTCCTGAGTCGTATGATACCGCACACCTCGCATCACTTGTAAAAAATATTAAAGC
TGGGGCAAAAACGATTGGGATAAGACAGTATGCACATCCGATCCATGATGTAACGGGGGTGATAAAAACTGTTAATAAGC
CGGAAATATTAATCATTGAAGGGCTAAACGTTATGCGGCATCCGGTAAAAACAGTGGTTGACCTGGGTATTTATATTGAA
GCACCGAAGAGATCTGTATTCAAATGGTATGTAAAAAGATTTTTTGAACTGAGGGCGCAACATGAGAAAAACACATATTT
TCGAAAGTATGCGAATCTCCCCAGAAGACAGTGTATAAAAATGCTAAAACAAGTTTGGCGCGACGTAAACCGAAAAAACT
TCACGGAAAATATTTTGCCAGTGAAACATACGGCAGACTTTATTGTGTATAAAAATCCGAGACATAAAATGACACTTTAC
AGAAATGAAGCTAGCTCTTCTGGATTTCCTGTTTGA

Upstream 100 bases:

>100_bases
TGCAAACACACCTGCAGTAGAGAGAGATGCGCTTCAATAATAACATACACTCAGACATATGTTCAAATCTATTAGATATG
AATTTATATGAAAGAGTTAT

Downstream 100 bases:

>100_bases
AAAAATCTGCTAAATGCGAGCAGGCGCGCTCCGCTTTCTCCGGATTTAAATCCTCGACCATAATACGGATAAGAGGTTCT
GTGCCACTTGGACGAATTAC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MGIEVFKKDITKTYTEMLKDIRKRVRERGKVGKSFIIGITGSVAAGKSTLASDLAKMLDGISVEVISTDGYLYPNKILEQ
KGLMLKKGFPESYDTAHLASLVKNIKAGAKTIGIRQYAHPIHDVTGVIKTVNKPEILIIEGLNVMRHPVKTVVDLGIYIE
APKRSVFKWYVKRFFELRAQHEKNTYFRKYANLPRRQCIKMLKQVWRDVNRKNFTENILPVKHTADFIVYKNPRHKMTLY
RNEASSSGFPV

Sequences:

>Translated_251_residues
MGIEVFKKDITKTYTEMLKDIRKRVRERGKVGKSFIIGITGSVAAGKSTLASDLAKMLDGISVEVISTDGYLYPNKILEQ
KGLMLKKGFPESYDTAHLASLVKNIKAGAKTIGIRQYAHPIHDVTGVIKTVNKPEILIIEGLNVMRHPVKTVVDLGIYIE
APKRSVFKWYVKRFFELRAQHEKNTYFRKYANLPRRQCIKMLKQVWRDVNRKNFTENILPVKHTADFIVYKNPRHKMTLY
RNEASSSGFPV
>Mature_250_residues
GIEVFKKDITKTYTEMLKDIRKRVRERGKVGKSFIIGITGSVAAGKSTLASDLAKMLDGISVEVISTDGYLYPNKILEQK
GLMLKKGFPESYDTAHLASLVKNIKAGAKTIGIRQYAHPIHDVTGVIKTVNKPEILIIEGLNVMRHPVKTVVDLGIYIEA
PKRSVFKWYVKRFFELRAQHEKNTYFRKYANLPRRQCIKMLKQVWRDVNRKNFTENILPVKHTADFIVYKNPRHKMTLYR
NEASSSGFPV

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=219, Percent_Identity=41.0958904109589, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 28757; Mature: 28626

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEVFKKDITKTYTEMLKDIRKRVRERGKVGKSFIIGITGSVAAGKSTLASDLAKMLDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
ISVEVISTDGYLYPNKILEQKGLMLKKGFPESYDTAHLASLVKNIKAGAKTIGIRQYAHP
CEEEEEECCCEECHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IHDVTGVIKTVNKPEILIIEGLNVMRHPVKTVVDLGIYIEAPKRSVFKWYVKRFFELRAQ
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHH
HEKNTYFRKYANLPRRQCIKMLKQVWRDVNRKNFTENILPVKHTADFIVYKNPRHKMTLY
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCEEEEECCCCCEEEE
RNEASSSGFPV
ECCCCCCCCCC
>Mature Secondary Structure 
GIEVFKKDITKTYTEMLKDIRKRVRERGKVGKSFIIGITGSVAAGKSTLASDLAKMLDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
ISVEVISTDGYLYPNKILEQKGLMLKKGFPESYDTAHLASLVKNIKAGAKTIGIRQYAHP
CEEEEEECCCEECHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IHDVTGVIKTVNKPEILIIEGLNVMRHPVKTVVDLGIYIEAPKRSVFKWYVKRFFELRAQ
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHH
HEKNTYFRKYANLPRRQCIKMLKQVWRDVNRKNFTENILPVKHTADFIVYKNPRHKMTLY
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCEEEEECCCCCEEEE
RNEASSSGFPV
ECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA