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The map label for this gene is rpoB [H]

Identifier: 28572249

GI number: 28572249

Start: 73945

End: 77412

Strand: Direct

Name: rpoB [H]

Synonym: TW081

Alternate gene names: 28572249

Gene position: 73945-77412 (Clockwise)

Preceding gene: 28572248

Following gene: 28572250

Centisome position: 7.99

GC content: 50.46

Gene sequence:

>3468_bases
TTGTTTGGGGTAGGTTTTTTGGCTTTTGCTAAGGGTAAAAGGGTTTGTGCGATAGGTCGCTCCTCTCTCGGTAAGATCTC
TGATCCGCTTGAGGTTCCGAACCTTCTTGATTTGCAGCTCGATAGTTTTGACTGGCTCATAGGCGGCCCTAGGTGGCGCG
CCGCCCTTGATGCTTACCGCAAAAATCCGTCAGGCGCCCCAATTGCCGAAAAGAGTGGGCTGGATGAGGTGTTTGATGAG
ATATCCCCCATAGAAGATTCGGCTGGCAATATGCAGCTTAATTTCTCCAAGCCGGTTCTGGAGGCCGAAGAGTTGAGCGT
AAGGGAATGCCGTGTTCGAGGCAGGACCTATTCGGCACCCCTGTATGTTGAGGCCGAGTTCATGAATCATGATACGGGCG
AGATAAAGACTCAGACGGTTTTTATGGGCGATTTCCCGCTTATGACTGACAAGGGTACATTCGTCATAAACGGCACCGAG
AGAGTTGTTGTCTCTCAGCTTGTTCGCAGCCCTGGTGTTTATTTTGAGCGCACGCCGGAAAAAAACAGTGAAAAGGATCT
TTTTTCGGGCAGAATAATCCCCGCTCGCGGTGCTTGGCTAGAATTCGAAGTTGACAGGCATGACCAGCTTGGCGTTAGGG
TTGACAGGAAGCGCAGGCAGCCGGTTATTTTCTTTCTGAGAGCAATTGGCATGACTGATGATGAGATCAGGGATGCATTT
GGCGAGTTTGAATCAATAAGCGTCCAGCACGAAAAGAATATTGGGCTGTCCAGAGATGACGCGCTCCGGGAAATATACCG
TCGCGTTCGTCCGGGGGAGCAGGCATCGGCTGAGGCTGGGCGTGCACTCTTAGAGAATTTTTACTTTACCAGCAGACGTT
TTGACCTGGCAAGGGTTGGAAGGTACAAAGTAAATCGCAAACTCGGTGTTGATGTTGATCCAACTCGGATGGTTCTTACG
AGGTCGGATATTATCGCAACAATTCGTTATCTCGCGGCCTTGCATCTCGGTTTCTCCGAGGTTGCGGTGCTAAACAGCAA
CAAGAGTGTACCAATTTCAACCGATGATATTGACCATCTTGGTAATAGGCGCATTAGACCGGTTGGTGAGTTGGTGCAAA
ACCAGCTCCGGGCTGGTCTGGCCAGAATGGAGCGGGTTGTGAGAGAGCGCATGACAACCCAGGATATAGAGGCGATTATC
CCGCAGACACTCATAAATGTCATGCCAATTGTTGCAGCGCTGAAGGAGTTTTATGGCACCAGCCAGCTCTCGCAGTTTAT
GGATCAGAATAACCCCCTTGCCGGCCTTACGCACAAGAGGCGCTTGTCAGCTCTTGGCCCCGGTGGACTGTCCCGCGAAC
GTGCCGGTGTTGAGGTTCGAGACGTAAATCCCAGTCATTACGGCAGGATGTGTCCGATCGAAACCCCAGAAGGTCCAAAT
ATTGGCCTTATAGGGTCTTTAGCGTGCTATTCCAGGGTGAACAGTTTCGGCTTTATAGAAACCCCATATAGACGTGTTGT
CAACGGAAAAGTCACAGACGATATTGAGTATATGACAGCAACACAGGAAGATGAGCATGCGATTGCCCAGGCAAGCACTC
CGCTGCGACCGGACAACTCGTTTGTTGATGAGCGTGTTCTGGTTCGCCGAAAAGGTGGAGAGGTCGAGGTTGTACCGGCC
GATCAGGTTGATTATATGGATGTGTCTGGACGTCAGATGGTGTCTGTTGCAACTTCGCTTATACCCTTCCTTGAACATAA
TGACGCTAACCGTGCTCTCATGGGATCGAATATGCAGAGACAGGCTGTACCACTTCTGGTTACGGAGAGTCCCCTGGTCG
GCACAGGTATGGAGCGGTATGTAGCGATCGATGCGGGTGATGTTTTAATTGCCGAGGATCCGGGCATTGTGGGGGATGTT
TCCGCTGATGTTGTCACTGTCAAGCAGGATGACGGGAAACATCGCGACTACCATGTTGGTAAATTTGTTCGTTCAAATCA
GGGCAACTGTTACAACCAGCGAGTTGTGGTCCGATCCGGAGATCGTGTAGAAAAAGGTACAGTTCTTGCAGATGGTCCAT
GTACTGACAAAGGTGAGCTTAGTCTTGGTAGAAATCTTCTGGTTGCGTTCATGCCCTGGGAGGGCTATAACTTTGAGGAT
GCGATAATTATCAGCCAGAATTTGGTCAAGGACGACACCCTTTCGTCAATCCACATAGAAGAACATGAGGTTAGCACCCG
GGATACGAAGCTGGGCAGTGAAGAAATAACACGAGACCTTCCGAATGTAAGCATGGATTACATAAAGGACTTGGACGAAC
GGGGTATTATCCGGATTGGCGCTGAGGTTGGCCCTGGGGACATTTTGGTTGGTAAGGTGACCCCAAAGGGCGAGACCGAA
CTCAGCGCGGAAGAGCGTTTGCTCAGGGCTATCTTTAACGAGAAGAGCATGGAGGTTCGCGACACAAGTTTGAAGGTCCC
ACACGGGCAGCAGGGGACCGTAATCGATGTTAAGTTGTTTGATGCGGTTGACGGTGAAGATAAGCTGGGTGCTGGCATAA
ATCAGCGGGTTGTTGTGTACATAGCGCATAAGCGCAAGATTACGGAGGGAGATAAGCTTGCTGGGCGCCATGGCAACAAG
GGTGTTATTTCAAAGATCCTTCCGGTAGAGGATATGCCCTTCATGGCTGATGGGACCCCCGTTGATATAATCCTTAATCC
GCTCGGCGTGCCCGCGCGTATGAACTTCGGGCAGGTTTTGGAAACCCATTTGGGGTGGATCTCTAAGCAAGGATGGAAAA
TAGAGGGTGATCCTGATTGGGCAAAAGATATTCGGGTGCGCGAGGCGCAGCCTGATAGTAGGGTTTCAAGTCCGGTTTTT
GATGGAATTTCCGAAGGGGAGATAACCGGGCTTTTTTCTTCTGTATTTCCAAACCGTGATGGTGAGCGTGCTGTCGGTTC
TGATGGTAAGGCTATTCTCTATGATGGCCGCACGGGGGAGCCCTTCCCGGAACCTATTTCCGTCGGTTACATGTATGTCC
TAAAGTTGCACCATCTGGTAGACGACAAGATTCATGCTCGCTCAACAGGACCGTATTCGATGATAACCCAGCAACCGCTG
GGCGGCAAGGCACAATTCGGTGGGCAGCGCTTCGGAGAGATGGAGGTGTGGGCGCTTGAGGCATATGGTGCAGCGCACGC
ACTCCAAGAGTTGCTAACAATAAAGTCTGATGACGTTGTTGGCCGGGTAAAGGTATACGATGCGATTGTCAAGGGTTATC
CAATTCCTACCCCCGGTGTGCCTGAATCATTTAAGGTTATTGTCAAGGAAATGCAGTCTTTGTGCATAAATATTGAGGTT
GTTTCTGACGGTGAGGATGATGTTTCCGCTGATGCTGAAACCCTACAGATAGAAGAAGGTCTGGATACGTCTCCCAAGGT
AGAAGTTGGTTCGCTTGAAGAGGTCTAG

Upstream 100 bases:

>100_bases
TTTGCTACAATCATTCTCGCTGTCTCGCCACTTGCCTTCATATTGCGGTCGGCTCTGGCTTTGTCGGGGTTTTTCTTCCT
CTTGCCCGTTTTGGGTGTCT

Downstream 100 bases:

>100_bases
TCGGGCATTCGCAAAAGAGGTTTGTTTTGTCTACATCTTTTAAAGAAATCCGGGTTAGTATGGCCACGACTGAAGATATT
CGTCGTTGGTCATATGGCGT

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1155; Mature: 1155

Protein sequence:

>1155_residues
MFGVGFLAFAKGKRVCAIGRSSLGKISDPLEVPNLLDLQLDSFDWLIGGPRWRAALDAYRKNPSGAPIAEKSGLDEVFDE
ISPIEDSAGNMQLNFSKPVLEAEELSVRECRVRGRTYSAPLYVEAEFMNHDTGEIKTQTVFMGDFPLMTDKGTFVINGTE
RVVVSQLVRSPGVYFERTPEKNSEKDLFSGRIIPARGAWLEFEVDRHDQLGVRVDRKRRQPVIFFLRAIGMTDDEIRDAF
GEFESISVQHEKNIGLSRDDALREIYRRVRPGEQASAEAGRALLENFYFTSRRFDLARVGRYKVNRKLGVDVDPTRMVLT
RSDIIATIRYLAALHLGFSEVAVLNSNKSVPISTDDIDHLGNRRIRPVGELVQNQLRAGLARMERVVRERMTTQDIEAII
PQTLINVMPIVAALKEFYGTSQLSQFMDQNNPLAGLTHKRRLSALGPGGLSRERAGVEVRDVNPSHYGRMCPIETPEGPN
IGLIGSLACYSRVNSFGFIETPYRRVVNGKVTDDIEYMTATQEDEHAIAQASTPLRPDNSFVDERVLVRRKGGEVEVVPA
DQVDYMDVSGRQMVSVATSLIPFLEHNDANRALMGSNMQRQAVPLLVTESPLVGTGMERYVAIDAGDVLIAEDPGIVGDV
SADVVTVKQDDGKHRDYHVGKFVRSNQGNCYNQRVVVRSGDRVEKGTVLADGPCTDKGELSLGRNLLVAFMPWEGYNFED
AIIISQNLVKDDTLSSIHIEEHEVSTRDTKLGSEEITRDLPNVSMDYIKDLDERGIIRIGAEVGPGDILVGKVTPKGETE
LSAEERLLRAIFNEKSMEVRDTSLKVPHGQQGTVIDVKLFDAVDGEDKLGAGINQRVVVYIAHKRKITEGDKLAGRHGNK
GVISKILPVEDMPFMADGTPVDIILNPLGVPARMNFGQVLETHLGWISKQGWKIEGDPDWAKDIRVREAQPDSRVSSPVF
DGISEGEITGLFSSVFPNRDGERAVGSDGKAILYDGRTGEPFPEPISVGYMYVLKLHHLVDDKIHARSTGPYSMITQQPL
GGKAQFGGQRFGEMEVWALEAYGAAHALQELLTIKSDDVVGRVKVYDAIVKGYPIPTPGVPESFKVIVKEMQSLCINIEV
VSDGEDDVSADAETLQIEEGLDTSPKVEVGSLEEV

Sequences:

>Translated_1155_residues
MFGVGFLAFAKGKRVCAIGRSSLGKISDPLEVPNLLDLQLDSFDWLIGGPRWRAALDAYRKNPSGAPIAEKSGLDEVFDE
ISPIEDSAGNMQLNFSKPVLEAEELSVRECRVRGRTYSAPLYVEAEFMNHDTGEIKTQTVFMGDFPLMTDKGTFVINGTE
RVVVSQLVRSPGVYFERTPEKNSEKDLFSGRIIPARGAWLEFEVDRHDQLGVRVDRKRRQPVIFFLRAIGMTDDEIRDAF
GEFESISVQHEKNIGLSRDDALREIYRRVRPGEQASAEAGRALLENFYFTSRRFDLARVGRYKVNRKLGVDVDPTRMVLT
RSDIIATIRYLAALHLGFSEVAVLNSNKSVPISTDDIDHLGNRRIRPVGELVQNQLRAGLARMERVVRERMTTQDIEAII
PQTLINVMPIVAALKEFYGTSQLSQFMDQNNPLAGLTHKRRLSALGPGGLSRERAGVEVRDVNPSHYGRMCPIETPEGPN
IGLIGSLACYSRVNSFGFIETPYRRVVNGKVTDDIEYMTATQEDEHAIAQASTPLRPDNSFVDERVLVRRKGGEVEVVPA
DQVDYMDVSGRQMVSVATSLIPFLEHNDANRALMGSNMQRQAVPLLVTESPLVGTGMERYVAIDAGDVLIAEDPGIVGDV
SADVVTVKQDDGKHRDYHVGKFVRSNQGNCYNQRVVVRSGDRVEKGTVLADGPCTDKGELSLGRNLLVAFMPWEGYNFED
AIIISQNLVKDDTLSSIHIEEHEVSTRDTKLGSEEITRDLPNVSMDYIKDLDERGIIRIGAEVGPGDILVGKVTPKGETE
LSAEERLLRAIFNEKSMEVRDTSLKVPHGQQGTVIDVKLFDAVDGEDKLGAGINQRVVVYIAHKRKITEGDKLAGRHGNK
GVISKILPVEDMPFMADGTPVDIILNPLGVPARMNFGQVLETHLGWISKQGWKIEGDPDWAKDIRVREAQPDSRVSSPVF
DGISEGEITGLFSSVFPNRDGERAVGSDGKAILYDGRTGEPFPEPISVGYMYVLKLHHLVDDKIHARSTGPYSMITQQPL
GGKAQFGGQRFGEMEVWALEAYGAAHALQELLTIKSDDVVGRVKVYDAIVKGYPIPTPGVPESFKVIVKEMQSLCINIEV
VSDGEDDVSADAETLQIEEGLDTSPKVEVGSLEEV
>Mature_1155_residues
MFGVGFLAFAKGKRVCAIGRSSLGKISDPLEVPNLLDLQLDSFDWLIGGPRWRAALDAYRKNPSGAPIAEKSGLDEVFDE
ISPIEDSAGNMQLNFSKPVLEAEELSVRECRVRGRTYSAPLYVEAEFMNHDTGEIKTQTVFMGDFPLMTDKGTFVINGTE
RVVVSQLVRSPGVYFERTPEKNSEKDLFSGRIIPARGAWLEFEVDRHDQLGVRVDRKRRQPVIFFLRAIGMTDDEIRDAF
GEFESISVQHEKNIGLSRDDALREIYRRVRPGEQASAEAGRALLENFYFTSRRFDLARVGRYKVNRKLGVDVDPTRMVLT
RSDIIATIRYLAALHLGFSEVAVLNSNKSVPISTDDIDHLGNRRIRPVGELVQNQLRAGLARMERVVRERMTTQDIEAII
PQTLINVMPIVAALKEFYGTSQLSQFMDQNNPLAGLTHKRRLSALGPGGLSRERAGVEVRDVNPSHYGRMCPIETPEGPN
IGLIGSLACYSRVNSFGFIETPYRRVVNGKVTDDIEYMTATQEDEHAIAQASTPLRPDNSFVDERVLVRRKGGEVEVVPA
DQVDYMDVSGRQMVSVATSLIPFLEHNDANRALMGSNMQRQAVPLLVTESPLVGTGMERYVAIDAGDVLIAEDPGIVGDV
SADVVTVKQDDGKHRDYHVGKFVRSNQGNCYNQRVVVRSGDRVEKGTVLADGPCTDKGELSLGRNLLVAFMPWEGYNFED
AIIISQNLVKDDTLSSIHIEEHEVSTRDTKLGSEEITRDLPNVSMDYIKDLDERGIIRIGAEVGPGDILVGKVTPKGETE
LSAEERLLRAIFNEKSMEVRDTSLKVPHGQQGTVIDVKLFDAVDGEDKLGAGINQRVVVYIAHKRKITEGDKLAGRHGNK
GVISKILPVEDMPFMADGTPVDIILNPLGVPARMNFGQVLETHLGWISKQGWKIEGDPDWAKDIRVREAQPDSRVSSPVF
DGISEGEITGLFSSVFPNRDGERAVGSDGKAILYDGRTGEPFPEPISVGYMYVLKLHHLVDDKIHARSTGPYSMITQQPL
GGKAQFGGQRFGEMEVWALEAYGAAHALQELLTIKSDDVVGRVKVYDAIVKGYPIPTPGVPESFKVIVKEMQSLCINIEV
VSDGEDDVSADAETLQIEEGLDTSPKVEVGSLEEV

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908503, Length=1208, Percent_Identity=22.8476821192053, Blast_Score=163, Evalue=1e-39,
Organism=Homo sapiens, GI238908505, Length=1144, Percent_Identity=22.8146853146853, Blast_Score=158, Evalue=3e-38,
Organism=Homo sapiens, GI4505941, Length=447, Percent_Identity=28.8590604026846, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI33469941, Length=394, Percent_Identity=27.1573604060914, Blast_Score=128, Evalue=4e-29,
Organism=Homo sapiens, GI212286172, Length=394, Percent_Identity=27.1573604060914, Blast_Score=127, Evalue=5e-29,
Organism=Escherichia coli, GI1790419, Length=590, Percent_Identity=55.7627118644068, Blast_Score=657, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=387, Percent_Identity=31.5245478036176, Blast_Score=159, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25144348, Length=1131, Percent_Identity=22.9000884173298, Blast_Score=156, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17506623, Length=209, Percent_Identity=33.0143540669856, Blast_Score=105, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324781, Length=1087, Percent_Identity=23.3670653173873, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324725, Length=389, Percent_Identity=31.6195372750643, Blast_Score=155, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6325267, Length=393, Percent_Identity=27.2264631043257, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136444, Length=387, Percent_Identity=29.4573643410853, Blast_Score=146, Evalue=9e-35,
Organism=Drosophila melanogaster, GI17647877, Length=394, Percent_Identity=30.9644670050761, Blast_Score=131, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17136446, Length=748, Percent_Identity=23.6631016042781, Blast_Score=125, Evalue=2e-28,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 127714; Mature: 127714

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGVGFLAFAKGKRVCAIGRSSLGKISDPLEVPNLLDLQLDSFDWLIGGPRWRAALDAYR
CCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCHHHHHHHHHH
KNPSGAPIAEKSGLDEVFDEISPIEDSAGNMQLNFSKPVLEAEELSVRECRVRGRTYSAP
CCCCCCCCHHHCCHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEECCC
LYVEAEFMNHDTGEIKTQTVFMGDFPLMTDKGTFVINGTERVVVSQLVRSPGVYFERTPE
EEEEEEECCCCCCCEEEEEEEECCCCEEECCCEEEECCCHHHHHHHHHHCCCCEEEECCC
KNSEKDLFSGRIIPARGAWLEFEVDRHDQLGVRVDRKRRQPVIFFLRAIGMTDDEIRDAF
CCCCCHHHCCCEEECCCCEEEEEECCCCCCCCEECCCCCCCCEEEEHHHCCCHHHHHHHH
GEFESISVQHEKNIGLSRDDALREIYRRVRPGEQASAEAGRALLENFYFTSRRFDLARVG
CCHHEEEEEHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHC
RYKVNRKLGVDVDPTRMVLTRSDIIATIRYLAALHLGFSEVAVLNSNKSVPISTDDIDHL
CEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCHHHH
GNRRIRPVGELVQNQLRAGLARMERVVRERMTTQDIEAIIPQTLINVMPIVAALKEFYGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
SQLSQFMDQNNPLAGLTHKRRLSALGPGGLSRERAGVEVRDVNPSHYGRMCPIETPEGPN
HHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHCCCEEEECCCCCCCCCCCCCCCCCCC
IGLIGSLACYSRVNSFGFIETPYRRVVNGKVTDDIEYMTATQEDEHAIAQASTPLRPDNS
CCEEHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHEECCCCHHHHHHHCCCCCCCCCC
FVDERVLVRRKGGEVEVVPADQVDYMDVSGRQMVSVATSLIPFLEHNDANRALMGSNMQR
HHHHHHHEEECCCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCCCC
QAVPLLVTESPLVGTGMERYVAIDAGDVLIAEDPGIVGDVSADVVTVKQDDGKHRDYHVG
CCCCEEEECCCCCCCCCCEEEEEECCCEEEECCCCCEEECCCCEEEEECCCCCCCCEEHH
KFVRSNQGNCYNQRVVVRSGDRVEKGTVLADGPCTDKGELSLGRNLLVAFMPWEGYNFED
HHHCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCC
AIIISQNLVKDDTLSSIHIEEHEVSTRDTKLGSEEITRDLPNVSMDYIKDLDERGIIRIG
EEEEECCCCCCCCCCEEEEECCCCCCCHHCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEE
AEVGPGDILVGKVTPKGETELSAEERLLRAIFNEKSMEVRDTSLKVPHGQQGTVIDVKLF
CCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEECCEEECCCCCCCCEEEEEEE
DAVDGEDKLGAGINQRVVVYIAHKRKITEGDKLAGRHGNKGVISKILPVEDMPFMADGTP
ECCCCCHHHCCCCCCEEEEEEEECCCCCCCCHHCCCCCCCCHHHHCCCCCCCCCCCCCCC
VDIILNPLGVPARMNFGQVLETHLGWISKQGWKIEGDPDWAKDIRVREAQPDSRVSSPVF
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCHHHCCEEECCCCCCCCCCHHH
DGISEGEITGLFSSVFPNRDGERAVGSDGKAILYDGRTGEPFPEPISVGYMYVLKLHHLV
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
DDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHALQELLTIKSDDVV
CCCHHCCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCE
GRVKVYDAIVKGYPIPTPGVPESFKVIVKEMQSLCINIEVVSDGEDDVSADAETLQIEEG
EHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCEEEECCC
LDTSPKVEVGSLEEV
CCCCCCEECCCCCCC
>Mature Secondary Structure
MFGVGFLAFAKGKRVCAIGRSSLGKISDPLEVPNLLDLQLDSFDWLIGGPRWRAALDAYR
CCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCHHHHHHHHHH
KNPSGAPIAEKSGLDEVFDEISPIEDSAGNMQLNFSKPVLEAEELSVRECRVRGRTYSAP
CCCCCCCCHHHCCHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEECCC
LYVEAEFMNHDTGEIKTQTVFMGDFPLMTDKGTFVINGTERVVVSQLVRSPGVYFERTPE
EEEEEEECCCCCCCEEEEEEEECCCCEEECCCEEEECCCHHHHHHHHHHCCCCEEEECCC
KNSEKDLFSGRIIPARGAWLEFEVDRHDQLGVRVDRKRRQPVIFFLRAIGMTDDEIRDAF
CCCCCHHHCCCEEECCCCEEEEEECCCCCCCCEECCCCCCCCEEEEHHHCCCHHHHHHHH
GEFESISVQHEKNIGLSRDDALREIYRRVRPGEQASAEAGRALLENFYFTSRRFDLARVG
CCHHEEEEEHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHC
RYKVNRKLGVDVDPTRMVLTRSDIIATIRYLAALHLGFSEVAVLNSNKSVPISTDDIDHL
CEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCHHHH
GNRRIRPVGELVQNQLRAGLARMERVVRERMTTQDIEAIIPQTLINVMPIVAALKEFYGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
SQLSQFMDQNNPLAGLTHKRRLSALGPGGLSRERAGVEVRDVNPSHYGRMCPIETPEGPN
HHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHCCCEEEECCCCCCCCCCCCCCCCCCC
IGLIGSLACYSRVNSFGFIETPYRRVVNGKVTDDIEYMTATQEDEHAIAQASTPLRPDNS
CCEEHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHEECCCCHHHHHHHCCCCCCCCCC
FVDERVLVRRKGGEVEVVPADQVDYMDVSGRQMVSVATSLIPFLEHNDANRALMGSNMQR
HHHHHHHEEECCCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCCCC
QAVPLLVTESPLVGTGMERYVAIDAGDVLIAEDPGIVGDVSADVVTVKQDDGKHRDYHVG
CCCCEEEECCCCCCCCCCEEEEEECCCEEEECCCCCEEECCCCEEEEECCCCCCCCEEHH
KFVRSNQGNCYNQRVVVRSGDRVEKGTVLADGPCTDKGELSLGRNLLVAFMPWEGYNFED
HHHCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCC
AIIISQNLVKDDTLSSIHIEEHEVSTRDTKLGSEEITRDLPNVSMDYIKDLDERGIIRIG
EEEEECCCCCCCCCCEEEEECCCCCCCHHCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEE
AEVGPGDILVGKVTPKGETELSAEERLLRAIFNEKSMEVRDTSLKVPHGQQGTVIDVKLF
CCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEECCEEECCCCCCCCEEEEEEE
DAVDGEDKLGAGINQRVVVYIAHKRKITEGDKLAGRHGNKGVISKILPVEDMPFMADGTP
ECCCCCHHHCCCCCCEEEEEEEECCCCCCCCHHCCCCCCCCHHHHCCCCCCCCCCCCCCC
VDIILNPLGVPARMNFGQVLETHLGWISKQGWKIEGDPDWAKDIRVREAQPDSRVSSPVF
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCHHHCCEEECCCCCCCCCCHHH
DGISEGEITGLFSSVFPNRDGERAVGSDGKAILYDGRTGEPFPEPISVGYMYVLKLHHLV
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
DDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHALQELLTIKSDDVV
CCCHHCCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCE
GRVKVYDAIVKGYPIPTPGVPESFKVIVKEMQSLCINIEVVSDGEDDVSADAETLQIEEG
EHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCEEEECCC
LDTSPKVEVGSLEEV
CCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12606174 [H]