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The map label for this gene is trpG [H]

Identifier: 28572186

GI number: 28572186

Start: 11399

End: 12037

Strand: Direct

Name: trpG [H]

Synonym: TW011

Alternate gene names: 28572186

Gene position: 11399-12037 (Clockwise)

Preceding gene: 28572184

Following gene: 28572187

Centisome position: 1.23

GC content: 50.7

Gene sequence:

>639_bases
ATGTTCAAAGTCTTGGTTATTGACAACCACGACAGCTTTATCTACACGCTTGTAAATTATCTGCAGCAACTTGGGGTAAC
AACCAGTGTTGTGCGGAGTGATAACAATTGTCATTCGGTTGAGTCTATGCTGGGTGTGCATGACGCAGCTCTCATCTCAC
CCGGCCCCGGCACCCCCGAGGAAAGCGGCATCACCCTTTCTGTCATTCGAGCTGCTTACTCTACCTCTACCCCACTTCTT
GGGGTTTGCTTGGGCCATCAGGCCCTTGCCGTCGCGTTTGGCGGTGACATAGGGCCTTCCGGAAGGATTATGCACGGAAA
GTTGGTTACGGTGCGCCCTCGGCCCAGCGCCATATTCAAGGACCTCCCCACTGCTTTTACCGCAACAAGGTACAACTCAC
TTACTGTTACAAAGGTGCCGCAAGCATTGAGGGTAATAGCCAGAGCAGACTGTGGCGAAGTTATGGCACTTGAACACCGG
ACGGCACCAATGTATGGTGTGCAATTTCACCCAGAGTCTGCAGTTTCCGAATGGGGTTTTCGCATTTTGGGAAATTGGTT
ATACATATCAGGTTTCAACAAGGCCCTGGGAATATCCCGTGATCTGCCCATTGTTGTTTACAATACTCGTGTACGCTAA

Upstream 100 bases:

>100_bases
CACACGGGGTTATTTTCGCTGGACTCGTGTTTTTTTCTGCTCATGAACTCCTAAGGGCAGAGACTGCGCGCCTTGAGATA
CCCCTATTATATATACCGTT

Downstream 100 bases:

>100_bases
GAGGCTCGTGCATGCTGGGGTTTGTTGCCCGCTTCGTGCCTCTCAGGGTATTTCAAGGCTTGTTTGATTCAATGACTAAG
GTGTTTGTATTTGCGGAGGT

Product: glutamine amidotransferase

Products: NA

Alternate protein names: Anthranilate synthase component II; Glutamine amido-transferase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MFKVLVIDNHDSFIYTLVNYLQQLGVTTSVVRSDNNCHSVESMLGVHDAALISPGPGTPEESGITLSVIRAAYSTSTPLL
GVCLGHQALAVAFGGDIGPSGRIMHGKLVTVRPRPSAIFKDLPTAFTATRYNSLTVTKVPQALRVIARADCGEVMALEHR
TAPMYGVQFHPESAVSEWGFRILGNWLYISGFNKALGISRDLPIVVYNTRVR

Sequences:

>Translated_212_residues
MFKVLVIDNHDSFIYTLVNYLQQLGVTTSVVRSDNNCHSVESMLGVHDAALISPGPGTPEESGITLSVIRAAYSTSTPLL
GVCLGHQALAVAFGGDIGPSGRIMHGKLVTVRPRPSAIFKDLPTAFTATRYNSLTVTKVPQALRVIARADCGEVMALEHR
TAPMYGVQFHPESAVSEWGFRILGNWLYISGFNKALGISRDLPIVVYNTRVR
>Mature_212_residues
MFKVLVIDNHDSFIYTLVNYLQQLGVTTSVVRSDNNCHSVESMLGVHDAALISPGPGTPEESGITLSVIRAAYSTSTPLL
GVCLGHQALAVAFGGDIGPSGRIMHGKLVTVRPRPSAIFKDLPTAFTATRYNSLTVTKVPQALRVIARADCGEVMALEHR
TAPMYGVQFHPESAVSEWGFRILGNWLYISGFNKALGISRDLPIVVYNTRVR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=188, Percent_Identity=41.4893617021277, Blast_Score=145, Evalue=1e-36,
Organism=Escherichia coli, GI1787517, Length=189, Percent_Identity=33.8624338624339, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322638, Length=192, Percent_Identity=38.5416666666667, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324361, Length=214, Percent_Identity=30.3738317757009, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 22998; Mature: 22998

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS00442 GATASE_TYPE_I ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKVLVIDNHDSFIYTLVNYLQQLGVTTSVVRSDNNCHSVESMLGVHDAALISPGPGTPE
CEEEEEEECCCCHHHHHHHHHHHCCCEEEEHCCCCCHHHHHHHHCCCCCEEECCCCCCCC
ESGITLSVIRAAYSTSTPLLGVCLGHQALAVAFGGDIGPSGRIMHGKLVTVRPRPSAIFK
CCCCCCEEEHHHHCCCCCCEEEECCCCEEEEEECCCCCCCCEEEECEEEEECCCCHHHHH
DLPTAFTATRYNSLTVTKVPQALRVIARADCGEVMALEHRTAPMYGVQFHPESAVSEWGF
HCCCHHEECCCCCEEEEHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCHHHHHHCCC
RILGNWLYISGFNKALGISRDLPIVVYNTRVR
EEECCEEEEECCCHHCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MFKVLVIDNHDSFIYTLVNYLQQLGVTTSVVRSDNNCHSVESMLGVHDAALISPGPGTPE
CEEEEEEECCCCHHHHHHHHHHHCCCEEEEHCCCCCHHHHHHHHCCCCCEEECCCCCCCC
ESGITLSVIRAAYSTSTPLLGVCLGHQALAVAFGGDIGPSGRIMHGKLVTVRPRPSAIFK
CCCCCCEEEHHHHCCCCCCEEEECCCCEEEEEECCCCCCCCEEEECEEEEECCCCHHHHH
DLPTAFTATRYNSLTVTKVPQALRVIARADCGEVMALEHRTAPMYGVQFHPESAVSEWGF
HCCCHHEECCCCCEEEEHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCHHHHHHCCC
RILGNWLYISGFNKALGISRDLPIVVYNTRVR
EEECCEEEEECCCHHCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]