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The map label for this gene is trxA3 [H]

Identifier: 28379765

GI number: 28379765

Start: 3050198

End: 3050518

Strand: Direct

Name: trxA3 [H]

Synonym: lp_3437

Alternate gene names: 28379765

Gene position: 3050198-3050518 (Clockwise)

Preceding gene: 28379763

Following gene: 28379766

Centisome position: 92.2

GC content: 43.93

Gene sequence:

>321_bases
ATGATTAAAGAAATACATGACCAAGATTTTGCCAAAGAAACAGATACTGGTATCGCCGTTATTGATTTTCGCGCAGACTG
GTGCCCACCATGTCGCATGATGGACCCAATTCTTAAGTCCCTTTCTGAAGACCCAGCTTACAAGGACCAGGTCAACTTCG
TTTCATTGAATATTGACCATGACCAAGCTACGGCCAGTCAATTCCAAGTTCAAGGAATTCCAACCTTCCTGATTAAGAAA
GATGGCCAAGTCGTCAGTCACATGGTCGGAGCACGTCCTAAGCCTGATTTTGAAGCCGAACTCAAAAAAGCACTTGCTTA
A

Upstream 100 bases:

>100_bases
TTTTTAAATCCCTCCACGGCCAGAAGCAGAATACTTGCTCGTGTATACCTATGGGGGTATATTGTTTAGTGACAAATACT
TACTAAAGGAGTCAACTAAA

Downstream 100 bases:

>100_bases
TTACGAAAGGGGCATCATGAATCATGGCAACTACTGAAGAATATGTCACTAGCAAGCAGATCAAGACCCGGCTAAAACGC
TCGGCTGGTCAACTGGACGG

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MIKEIHDQDFAKETDTGIAVIDFRADWCPPCRMMDPILKSLSEDPAYKDQVNFVSLNIDHDQATASQFQVQGIPTFLIKK
DGQVVSHMVGARPKPDFEAELKKALA

Sequences:

>Translated_106_residues
MIKEIHDQDFAKETDTGIAVIDFRADWCPPCRMMDPILKSLSEDPAYKDQVNFVSLNIDHDQATASQFQVQGIPTFLIKK
DGQVVSHMVGARPKPDFEAELKKALA
>Mature_106_residues
MIKEIHDQDFAKETDTGIAVIDFRADWCPPCRMMDPILKSLSEDPAYKDQVNFVSLNIDHDQATASQFQVQGIPTFLIKK
DGQVVSHMVGARPKPDFEAELKKALA

Specific function: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=108, Percent_Identity=37.037037037037, Blast_Score=77, Evalue=3e-16,
Organism=Escherichia coli, GI1788936, Length=86, Percent_Identity=40.6976744186046, Blast_Score=72, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319925, Length=74, Percent_Identity=44.5945945945946, Blast_Score=68, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323072, Length=101, Percent_Identity=36.6336633663366, Blast_Score=65, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321648, Length=105, Percent_Identity=32.3809523809524, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11904; Mature: 11904

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEIHDQDFAKETDTGIAVIDFRADWCPPCRMMDPILKSLSEDPAYKDQVNFVSLNIDH
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
DQATASQFQVQGIPTFLIKKDGQVVSHMVGARPKPDFEAELKKALA
CHHHHHHEEECCCCEEEEECCCHHHHHHHCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MIKEIHDQDFAKETDTGIAVIDFRADWCPPCRMMDPILKSLSEDPAYKDQVNFVSLNIDH
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
DQATASQFQVQGIPTFLIKKDGQVVSHMVGARPKPDFEAELKKALA
CHHHHHHEEECCCCEEEEECCCHHHHHHHCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]