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The map label for this gene is ycsN [H]

Identifier: 28379674

GI number: 28379674

Start: 2953772

End: 2954692

Strand: Direct

Name: ycsN [H]

Synonym: lp_3318

Alternate gene names: 28379674

Gene position: 2953772-2954692 (Clockwise)

Preceding gene: 28379672

Following gene: 28379675

Centisome position: 89.28

GC content: 49.08

Gene sequence:

>921_bases
TTGAAAACGATTAATTTAGGTCACAGCAATATTCAAGCTTCCAGCGTGGCGCTTGGCATCATGCGCATGGACGCCTTGGA
TGTCGCTCAAGCCACCAAGGTTATCGATACCGCTGCTGATTTAGGCATCAATTACGTTGATTCAGCTGATATCTACGGTG
GTGGTCAATCATCGACCATCTTCGGTCAAGCACTCAAGCAGGCTCACGTATCGCGTGATCAGCTCTATATTCAGTCAAAA
GGCGGCATTGTTCCTGGCAAGCGTTACGACTTTTCCAAACAGCACATACTGGCAGCCGTGGATGGCGAGCTTCAACGCTT
AGGTGTTGATTATCTCGACACCTTCCTCCTCCATCGACCGGACGCCCTGATGGAACCCGAAGAAGTTGCTGCCGCTTTTG
ACAAGTTGCAAACTAGCGGCAAGGTGCGCCACTTTGGCGTCTCTAACTTCAATCCCATGCAAGTTGACATGCTTCAAGCG
GCACTAAACCAACGGCTCATCATTAACCAACTCCAATTTGGTATCATGCATACCGGTGCGATCGACTTTGGCTTGCACAC
GAACATGCAGGACGAACGTAGTCTTAACCACGACGGCGAGATGATCGAATACTCACGGCTCCATAAGATGACGATTCAAG
CTTGGTCGCCTTATCAATACGGTAACTTCGCGGGTATCTTCTTAGACAATCCGAAGTTTCCAGAACTTAATAATGCCATG
CAAGCACTCGCCGATGAGAAACAGGTCACTAAATCAGCTATTGCGACCGCATGGATTCTCCGGCACCCAGCCCACTTCCA
AGTCGTCCTTGGTACGATGAATCCGGAACATCTAGCTCAAAATGCTGCTGGAGCAGACGTTACGCTTTCTCGGCAAGAAT
GGTACGACATTTACTTTGCAGCTGGCAACGATTTACCTTAA

Upstream 100 bases:

>100_bases
GATTTACCAACAGTCGGCACCAGACGTAACCGTTTACATCCTCTTACGAAAACCGTATACTGAATTTAAATCAAGTTGCA
CATTGAGGAGGACTTTAGTT

Downstream 100 bases:

>100_bases
TCACGATCGACCTAACAGAATTGACGATTAGTTTTTACAATCAAAACGACGACCCCAAATCAGGATTGATTTTCAGGTCG
TCGTTTTTTAGACGTTTCAC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINYVDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSK
GGIVPGKRYDFSKQHILAAVDGELQRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQA
ALNQRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGNFAGIFLDNPKFPELNNAM
QALADEKQVTKSAIATAWILRHPAHFQVVLGTMNPEHLAQNAAGADVTLSRQEWYDIYFAAGNDLP

Sequences:

>Translated_306_residues
MKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINYVDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSK
GGIVPGKRYDFSKQHILAAVDGELQRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQA
ALNQRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGNFAGIFLDNPKFPELNNAM
QALADEKQVTKSAIATAWILRHPAHFQVVLGTMNPEHLAQNAAGADVTLSRQEWYDIYFAAGNDLP
>Mature_306_residues
MKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINYVDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSK
GGIVPGKRYDFSKQHILAAVDGELQRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQA
ALNQRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGNFAGIFLDNPKFPELNNAM
QALADEKQVTKSAIATAWILRHPAHFQVVLGTMNPEHLAQNAAGADVTLSRQEWYDIYFAAGNDLP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=320, Percent_Identity=25.3125, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI27436962, Length=316, Percent_Identity=25, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI27436966, Length=316, Percent_Identity=25, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI4504825, Length=316, Percent_Identity=24.6835443037975, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI27436969, Length=316, Percent_Identity=24.6835443037975, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI27436971, Length=318, Percent_Identity=23.8993710691824, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI48994888, Length=317, Percent_Identity=32.4921135646688, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788070, Length=332, Percent_Identity=25.9036144578313, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87081735, Length=323, Percent_Identity=24.7678018575851, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789375, Length=325, Percent_Identity=25.2307692307692, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788081, Length=257, Percent_Identity=26.8482490272374, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87082198, Length=295, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=127, Percent_Identity=31.496062992126, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=344, Percent_Identity=22.093023255814, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24646155, Length=165, Percent_Identity=32.7272727272727, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646159, Length=173, Percent_Identity=28.9017341040462, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 33862; Mature: 33862

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINYVDSADIYGGGQSSTI
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHH
FGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGELQRLGVDYLDTFLLHRP
HHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCHHHEEEEECCHHHHHCHHHHHHHHHCCC
DALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALNQRLIINQLQFGIMHTGA
CCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHCEEECCE
IDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGNFAGIFLDNPKFPELNNAM
EEECCCCCCCHHHCCCCCCCCHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCCCHHHHH
QALADEKQVTKSAIATAWILRHPAHFQVVLGTMNPEHLAQNAAGADVTLSRQEWYDIYFA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCCEEEECCCEEEEEEE
AGNDLP
CCCCCC
>Mature Secondary Structure
MKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINYVDSADIYGGGQSSTI
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHH
FGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGELQRLGVDYLDTFLLHRP
HHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCHHHEEEEECCHHHHHCHHHHHHHHHCCC
DALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALNQRLIINQLQFGIMHTGA
CCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHCEEECCE
IDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGNFAGIFLDNPKFPELNNAM
EEECCCCCCCHHHCCCCCCCCHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCCCHHHHH
QALADEKQVTKSAIATAWILRHPAHFQVVLGTMNPEHLAQNAAGADVTLSRQEWYDIYFA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCCEEEECCCEEEEEEE
AGNDLP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]