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The map label for this gene is kup2

Identifier: 28379645

GI number: 28379645

Start: 2918829

End: 2920871

Strand: Direct

Name: kup2

Synonym: lp_3279

Alternate gene names: 28379645

Gene position: 2918829-2920871 (Clockwise)

Preceding gene: 28379644

Following gene: 28379648

Centisome position: 88.23

GC content: 47.38

Gene sequence:

>2043_bases
ATGCGTAAGCAACGGATCCAGGAACGTTCATTGATTGGCATGTTAATCACATTAGGCGTCGTGTACGGGGACATCGGAAC
GTCACCGCTATACGTTATGAACGCCCTGATCAATGACGCGGGGCAACTTAAGAATGCAACACCTGATTATGTTATCGGCA
GTGTTTCATTAATCTTTTGGACGTTGATGCTCATTACAACGGTAAAGTACGTCCTGATTGCTTTACGCGCTGATAATCAT
CATGAAGGTGGCATTTTCGCCCTGTATGCACTGGTTCGTCACCGGGCCAAATGGTTAATTTTCGTCGCGTTGATTGGTGG
CGCCGCTTTGTTAGCAGATGGCACCCTAACACCTGCTGTGACAGTCACATCAGCAGTTGAAGGCTTAAAGGGATTACCCA
AACTGGGGGCTTTTTCCCAGTACCCGTGGCTCGTGCCTCTAACCGTTACGGTTATTTTACTGGTTCTCTTTATGATTCAA
GGGTTTGGTACTGCCGTCGTTGGCCGGTCATTCGGTCCCATGATGTTGCTCTGGTTCACCGTCATCGGCATCTTCGGTCT
GATCAACATCAGTCAGGCACCCGTCATTCTCAAAGCTTTCTCACCCGTTTACGCCGTACAAGTCTTATTCAATCCGGCTA
ATAAAATGGGAATTTTCATTCTTGGTAGTGTCTTCCTTGCAACGACCGGGGCTGAAGCGCTGTATTCTGATATGGGGCAC
GTTGGTAAAGCCAACATCGACGCCACTTGGCCGTTCGTATACACGACTTTGATTCTCAATTATCTTGGTCAGGGCGCGTG
GATGTTAACCCATTATCAGGATGCGGCATGGCGCAATGCCACCAATGTCAATCCGTTCTATGCCATGGTTCCTGCGGGCG
GTCAAATTGCAATGATTATCTTAGCCACGGCCGCAGCCATCATTGCGTCACAGGCCTTGATCACGGGCTCTTATACCTTA
GTTGACGAAGCAGTCGGTTTAAAGTTCTTACCACGTATGATTATCAAGCACCCCAGTAACGTTCGGAGCCAGATTTATAT
TGGTGCGATCAACTGGCTGTTATGTCTGGTCACCTTAGGAATCGTTTGGCTATTTCAAACTTCAGCTCACATGGAAGCGG
CGTATGGTTTAGCCATCACCTTAACAATGTTGATGACGACCATCCTGCTTAGCCAGTGGATTCACATGAAGGGCCACCGG
GCGCTGGCGCTAGCTTTATTATTCGGCTTTGGCGCACTGGAGACCGTCTTTCTAACGGCTAGTCTGACCAAGTTTATTCA
CGGTGGCTATTTGACCTTGGGGCTGACCCTCGTCATTTTCTTGATTATGGTCGTTTGGTTCTTTGGTAATCGCCGGCGTT
TGCGTTACAACCAGGCAAATGAACAGATTAGTCTGCTAGATTATCGTAATCAACTGATCCAGCTAAGCCACGATGATCAC
CTGCCAGTATTTGCAACGAATTTAGTCTACTTGGCTAAGGTCGACCATCAACACCGGGTTAAACGGTCAATTCTGTACTC
GATTTTAGATAAGCGGCCTAAACGCGCTAAGGTTTACTGGTTTATTACCATTAATGAAACCAACCGACCTTATGATTGTA
GTTACAGCATTGACATGCTAGGCACTCGAAATATCGTGGAAGTTCAACTCAACTTAGGTTTCCGTAAATCACAGCACATT
AATTTATATTTGCGCCAAATTGTCACGAACTTAATTGCAGATCACAGCATCGATCCCCAATATTCCCGTTACGGAATCAC
ACAACCTCGTCAAGTTGGCGATTTTAAATTTGTCGTTCAGAATCAGCAGATCATGGACCTTGCTAGCAACCCAACTATGG
GCCAGTTCGATCGACTACTAATTGGTGGTCGCGTTCTACTACAAAACATCACCCCATCTCCTGCTATCTGGTACGGCTTA
GCGTTTAGCGATGTCTTGGAAGAGACGATTCCGTTGTTCACGAAACCAGCAACGGACGCCACACTAACGAATTTGACGGT
CCACCATGCCCGCACGCCGCAACGGAATTCGCGCCAACCATAA

Upstream 100 bases:

>100_bases
GTTAACATGAGCAAATTTTTAGTTTGTCTGGTTAACCCCTTTTGAAAAAAGCTAGTATAGTATGAGTCACAGTTCTAATT
GAAGTGGGGGTCAATAATTC

Downstream 100 bases:

>100_bases
ATAAAAGACTAGTTTCAAGGAATTCAACCTTGAAACTAGTCTTTTATTATTAAAATCTATCAGTCAACACACTTATGTTT
GCGGCATAAACATTACCTTA

Product: potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MRKQRIQERSLIGMLITLGVVYGDIGTSPLYVMNALINDAGQLKNATPDYVIGSVSLIFWTLMLITTVKYVLIALRADNH
HEGGIFALYALVRHRAKWLIFVALIGGAALLADGTLTPAVTVTSAVEGLKGLPKLGAFSQYPWLVPLTVTVILLVLFMIQ
GFGTAVVGRSFGPMMLLWFTVIGIFGLINISQAPVILKAFSPVYAVQVLFNPANKMGIFILGSVFLATTGAEALYSDMGH
VGKANIDATWPFVYTTLILNYLGQGAWMLTHYQDAAWRNATNVNPFYAMVPAGGQIAMIILATAAAIIASQALITGSYTL
VDEAVGLKFLPRMIIKHPSNVRSQIYIGAINWLLCLVTLGIVWLFQTSAHMEAAYGLAITLTMLMTTILLSQWIHMKGHR
ALALALLFGFGALETVFLTASLTKFIHGGYLTLGLTLVIFLIMVVWFFGNRRRLRYNQANEQISLLDYRNQLIQLSHDDH
LPVFATNLVYLAKVDHQHRVKRSILYSILDKRPKRAKVYWFITINETNRPYDCSYSIDMLGTRNIVEVQLNLGFRKSQHI
NLYLRQIVTNLIADHSIDPQYSRYGITQPRQVGDFKFVVQNQQIMDLASNPTMGQFDRLLIGGRVLLQNITPSPAIWYGL
AFSDVLEETIPLFTKPATDATLTNLTVHHARTPQRNSRQP

Sequences:

>Translated_680_residues
MRKQRIQERSLIGMLITLGVVYGDIGTSPLYVMNALINDAGQLKNATPDYVIGSVSLIFWTLMLITTVKYVLIALRADNH
HEGGIFALYALVRHRAKWLIFVALIGGAALLADGTLTPAVTVTSAVEGLKGLPKLGAFSQYPWLVPLTVTVILLVLFMIQ
GFGTAVVGRSFGPMMLLWFTVIGIFGLINISQAPVILKAFSPVYAVQVLFNPANKMGIFILGSVFLATTGAEALYSDMGH
VGKANIDATWPFVYTTLILNYLGQGAWMLTHYQDAAWRNATNVNPFYAMVPAGGQIAMIILATAAAIIASQALITGSYTL
VDEAVGLKFLPRMIIKHPSNVRSQIYIGAINWLLCLVTLGIVWLFQTSAHMEAAYGLAITLTMLMTTILLSQWIHMKGHR
ALALALLFGFGALETVFLTASLTKFIHGGYLTLGLTLVIFLIMVVWFFGNRRRLRYNQANEQISLLDYRNQLIQLSHDDH
LPVFATNLVYLAKVDHQHRVKRSILYSILDKRPKRAKVYWFITINETNRPYDCSYSIDMLGTRNIVEVQLNLGFRKSQHI
NLYLRQIVTNLIADHSIDPQYSRYGITQPRQVGDFKFVVQNQQIMDLASNPTMGQFDRLLIGGRVLLQNITPSPAIWYGL
AFSDVLEETIPLFTKPATDATLTNLTVHHARTPQRNSRQP
>Mature_680_residues
MRKQRIQERSLIGMLITLGVVYGDIGTSPLYVMNALINDAGQLKNATPDYVIGSVSLIFWTLMLITTVKYVLIALRADNH
HEGGIFALYALVRHRAKWLIFVALIGGAALLADGTLTPAVTVTSAVEGLKGLPKLGAFSQYPWLVPLTVTVILLVLFMIQ
GFGTAVVGRSFGPMMLLWFTVIGIFGLINISQAPVILKAFSPVYAVQVLFNPANKMGIFILGSVFLATTGAEALYSDMGH
VGKANIDATWPFVYTTLILNYLGQGAWMLTHYQDAAWRNATNVNPFYAMVPAGGQIAMIILATAAAIIASQALITGSYTL
VDEAVGLKFLPRMIIKHPSNVRSQIYIGAINWLLCLVTLGIVWLFQTSAHMEAAYGLAITLTMLMTTILLSQWIHMKGHR
ALALALLFGFGALETVFLTASLTKFIHGGYLTLGLTLVIFLIMVVWFFGNRRRLRYNQANEQISLLDYRNQLIQLSHDDH
LPVFATNLVYLAKVDHQHRVKRSILYSILDKRPKRAKVYWFITINETNRPYDCSYSIDMLGTRNIVEVQLNLGFRKSQHI
NLYLRQIVTNLIADHSIDPQYSRYGITQPRQVGDFKFVVQNQQIMDLASNPTMGQFDRLLIGGRVLLQNITPSPAIWYGL
AFSDVLEETIPLFTKPATDATLTNLTVHHARTPQRNSRQP

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=452, Percent_Identity=38.9380530973451, Blast_Score=277, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP2_LACPL (Q88SV0)

Other databases:

- EMBL:   AL935261
- RefSeq:   NP_786537.1
- GeneID:   1062657
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_3279
- NMPDR:   fig|220668.1.peg.2671
- HOGENOM:   HBG351154
- OMA:   FILMTTW
- ProtClustDB:   CLSK581978
- BioCyc:   LPLA220668:LP_3279-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 75705; Mature: 75705

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10a991a0)-; HASH(0xf24d6e0)-; HASH(0x10562be0)-; HASH(0xed958e0)-; HASH(0xe9ee804)-; HASH(0x110f6f9c)-; HASH(0xf48c4a4)-; HASH(0x1122dab8)-; HASH(0x106e9eec)-; HASH(0x107ab914)-; HASH(0xfde690c)-; HASH(0x114fe960)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKQRIQERSLIGMLITLGVVYGDIGTSPLYVMNALINDAGQLKNATPDYVIGSVSLIFW
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TLMLITTVKYVLIALRADNHHEGGIFALYALVRHRAKWLIFVALIGGAALLADGTLTPAV
HHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHH
TVTSAVEGLKGLPKLGAFSQYPWLVPLTVTVILLVLFMIQGFGTAVVGRSFGPMMLLWFT
HHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHH
VIGIFGLINISQAPVILKAFSPVYAVQVLFNPANKMGIFILGSVFLATTGAEALYSDMGH
HHHHHHHHCCCCCCEEEECCCHHHEEHEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHCC
VGKANIDATWPFVYTTLILNYLGQGAWMLTHYQDAAWRNATNVNPFYAMVPAGGQIAMII
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCCCCEEEEECCCCCCHHHH
LATAAAIIASQALITGSYTLVDEAVGLKFLPRMIIKHPSNVRSQIYIGAINWLLCLVTLG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHH
IVWLFQTSAHMEAAYGLAITLTMLMTTILLSQWIHMKGHRALALALLFGFGALETVFLTA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLTKFIHGGYLTLGLTLVIFLIMVVWFFGNRRRLRYNQANEQISLLDYRNQLIQLSHDDH
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHEEECCCCC
LPVFATNLVYLAKVDHQHRVKRSILYSILDKRPKRAKVYWFITINETNRPYDCSYSIDML
CCCHHHCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEEEEC
GTRNIVEVQLNLGFRKSQHINLYLRQIVTNLIADHSIDPQYSRYGITQPRQVGDFKFVVQ
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEC
NQQIMDLASNPTMGQFDRLLIGGRVLLQNITPSPAIWYGLAFSDVLEETIPLFTKPATDA
CCHHHHHCCCCCCCHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
TLTNLTVHHARTPQRNSRQP
EEEEEEEECCCCCCCCCCCH
>Mature Secondary Structure
MRKQRIQERSLIGMLITLGVVYGDIGTSPLYVMNALINDAGQLKNATPDYVIGSVSLIFW
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TLMLITTVKYVLIALRADNHHEGGIFALYALVRHRAKWLIFVALIGGAALLADGTLTPAV
HHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHH
TVTSAVEGLKGLPKLGAFSQYPWLVPLTVTVILLVLFMIQGFGTAVVGRSFGPMMLLWFT
HHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHH
VIGIFGLINISQAPVILKAFSPVYAVQVLFNPANKMGIFILGSVFLATTGAEALYSDMGH
HHHHHHHHCCCCCCEEEECCCHHHEEHEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHCC
VGKANIDATWPFVYTTLILNYLGQGAWMLTHYQDAAWRNATNVNPFYAMVPAGGQIAMII
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCCCCEEEEECCCCCCHHHH
LATAAAIIASQALITGSYTLVDEAVGLKFLPRMIIKHPSNVRSQIYIGAINWLLCLVTLG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHH
IVWLFQTSAHMEAAYGLAITLTMLMTTILLSQWIHMKGHRALALALLFGFGALETVFLTA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLTKFIHGGYLTLGLTLVIFLIMVVWFFGNRRRLRYNQANEQISLLDYRNQLIQLSHDDH
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHEEECCCCC
LPVFATNLVYLAKVDHQHRVKRSILYSILDKRPKRAKVYWFITINETNRPYDCSYSIDML
CCCHHHCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEEEEC
GTRNIVEVQLNLGFRKSQHINLYLRQIVTNLIADHSIDPQYSRYGITQPRQVGDFKFVVQ
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEC
NQQIMDLASNPTMGQFDRLLIGGRVLLQNITPSPAIWYGLAFSDVLEETIPLFTKPATDA
CCHHHHHCCCCCCCHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
TLTNLTVHHARTPQRNSRQP
EEEEEEEECCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12566566