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The map label for this gene is yhdG [H]

Identifier: 28379644

GI number: 28379644

Start: 2917143

End: 2918567

Strand: Direct

Name: yhdG [H]

Synonym: lp_3278

Alternate gene names: 28379644

Gene position: 2917143-2918567 (Clockwise)

Preceding gene: 28379641

Following gene: 28379645

Centisome position: 88.18

GC content: 47.44

Gene sequence:

>1425_bases
ATGGATTTATCACACACGCGGTTACTCCGCAAAAAAGATATCAATGCCATGTTAGCCACTTATCACAGTCCGCTCAAAAA
GGAACTTAAAACATTTGACCTAACGATGCTGGGAATTGGGGCCATCATCGGGACCGGGATTTTCGTTTTAACTGGTACGG
GGGCCTTGACGGCTGGTCCCGGCCTAATGATCTCATTCGTCTTAGCTGCAATTGCTTGCCTGTTTGCTTCACTCTGCTAC
GCTGAATTCGCTGCGATGGTGCCTGAAAGTGGGTCAGCGTACACCTATGCCTACACAACCCTCGGCGAAATTGTTGCATT
CATTATCGGCTGGGACTTGATGTTAGAATACCTTTTCGCTGTCTCAACCGTTTCAGCGGGCTGGTCAGGCTACTTTCAAT
CATTCTTGGCGGGCTTCGGCCTCAAACTGCCCGCTGCTTTGTCGGCAGCTGCAGGTTCCGTCCCTGGTGTGACCAGCTAT
TTTAATCTGCCGGCCTTCACCATTATTATCCTGATTACCACTTTATTGTCTCTCGGGGTCAAAGAAACTAAACGCGTCAA
TAACGTCATGGTAGTGATTAAATTAGCCGTTGTTCTTTTATTCATCTTTACCGCAGTGCGCTTCATCAAGCCGGCAAACT
GGAGTCCGTTATTACCGTTTGGCTTCAAGGGCGTATTCGGCGCAGCTTCTAGCGTTTTCTTCGCCTTCATCGGTTTTGAC
GCCATTTCATCTAGCGTTGAAGAAACATTGGAACCATCCAAAACACTCCCACGTTCCATGTTACTGTCTCTTGGTATCTG
TACCATTCTCTACGTGGCTGTATCAGCCATCATGACTGGCGTGGTCCCATTTGAAACGTTTGCCAAGTACATTGATCATC
CGATTTCGGCCGTTCTTATTTACTCCGGTCAAAATTGGATGGCCGGAATCATTGACCTTGGCGCGATTCTTGGTATGACC
ACTGTAATGTTAGTCTGTCTCTACGGTCAAACTCGGATTTCCTTCTCCATGTCGCGGGATGGATTACTCCCCCATGTCTT
TAGCGATATTAGTGCCAAGACCGGTGCACCACTTAAATCAACCGTCTTATTTGGGTCGATTGCCGCAATCATGGGTGGCT
TTATTCCATTAGCTGACTTAGCTGAACTGGTGAATATCGGTACTTTGACTGCCTTTACCCTAGTTTCCTTCTCCATCTTA
CGGCTACGTAAAACACAACCAGATCTTCGGCGTCCCTTCAAAACGCCGTGGGTCCCGTTTGTACCAATCATGTCAATCAT
CTGTTGTGTCTTCCTACTAATCAACCTGAAGCCTGTCACTTGGATTCGCTTCGTGGTATGGTTAGCCATCGGTATGGTCG
TTTACTTTGGCTATTCCGTTAAACACTCCCAGTTGAAGACGGATACAGCCACCGATGAGAAATAA

Upstream 100 bases:

>100_bases
ACTATAGCCCATCAGAATATTTATTTTGGTCGGATTAACCATCGTAACTTTGTCAAAACCGATTAAACTAAAGCTATCAC
ATCGAAATGGGGCGATGATT

Downstream 100 bases:

>100_bases
TTGACTAGACTATTAAATTCAAAACTAATGGGCCGTTTCATTTCAGCGTTATCAACTGGAATGAAACGGCCCATTTTTTA
TCCTCTAAATACGAACAACC

Product: amino acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MDLSHTRLLRKKDINAMLATYHSPLKKELKTFDLTMLGIGAIIGTGIFVLTGTGALTAGPGLMISFVLAAIACLFASLCY
AEFAAMVPESGSAYTYAYTTLGEIVAFIIGWDLMLEYLFAVSTVSAGWSGYFQSFLAGFGLKLPAALSAAAGSVPGVTSY
FNLPAFTIIILITTLLSLGVKETKRVNNVMVVIKLAVVLLFIFTAVRFIKPANWSPLLPFGFKGVFGAASSVFFAFIGFD
AISSSVEETLEPSKTLPRSMLLSLGICTILYVAVSAIMTGVVPFETFAKYIDHPISAVLIYSGQNWMAGIIDLGAILGMT
TVMLVCLYGQTRISFSMSRDGLLPHVFSDISAKTGAPLKSTVLFGSIAAIMGGFIPLADLAELVNIGTLTAFTLVSFSIL
RLRKTQPDLRRPFKTPWVPFVPIMSIICCVFLLINLKPVTWIRFVVWLAIGMVVYFGYSVKHSQLKTDTATDEK

Sequences:

>Translated_474_residues
MDLSHTRLLRKKDINAMLATYHSPLKKELKTFDLTMLGIGAIIGTGIFVLTGTGALTAGPGLMISFVLAAIACLFASLCY
AEFAAMVPESGSAYTYAYTTLGEIVAFIIGWDLMLEYLFAVSTVSAGWSGYFQSFLAGFGLKLPAALSAAAGSVPGVTSY
FNLPAFTIIILITTLLSLGVKETKRVNNVMVVIKLAVVLLFIFTAVRFIKPANWSPLLPFGFKGVFGAASSVFFAFIGFD
AISSSVEETLEPSKTLPRSMLLSLGICTILYVAVSAIMTGVVPFETFAKYIDHPISAVLIYSGQNWMAGIIDLGAILGMT
TVMLVCLYGQTRISFSMSRDGLLPHVFSDISAKTGAPLKSTVLFGSIAAIMGGFIPLADLAELVNIGTLTAFTLVSFSIL
RLRKTQPDLRRPFKTPWVPFVPIMSIICCVFLLINLKPVTWIRFVVWLAIGMVVYFGYSVKHSQLKTDTATDEK
>Mature_474_residues
MDLSHTRLLRKKDINAMLATYHSPLKKELKTFDLTMLGIGAIIGTGIFVLTGTGALTAGPGLMISFVLAAIACLFASLCY
AEFAAMVPESGSAYTYAYTTLGEIVAFIIGWDLMLEYLFAVSTVSAGWSGYFQSFLAGFGLKLPAALSAAAGSVPGVTSY
FNLPAFTIIILITTLLSLGVKETKRVNNVMVVIKLAVVLLFIFTAVRFIKPANWSPLLPFGFKGVFGAASSVFFAFIGFD
AISSSVEETLEPSKTLPRSMLLSLGICTILYVAVSAIMTGVVPFETFAKYIDHPISAVLIYSGQNWMAGIIDLGAILGMT
TVMLVCLYGQTRISFSMSRDGLLPHVFSDISAKTGAPLKSTVLFGSIAAIMGGFIPLADLAELVNIGTLTAFTLVSFSIL
RLRKTQPDLRRPFKTPWVPFVPIMSIICCVFLLINLKPVTWIRFVVWLAIGMVVYFGYSVKHSQLKTDTATDEK

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=416, Percent_Identity=36.7788461538462, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI110347453, Length=403, Percent_Identity=35.4838709677419, Blast_Score=225, Evalue=7e-59,
Organism=Homo sapiens, GI258614005, Length=439, Percent_Identity=33.7129840546697, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI258614003, Length=439, Percent_Identity=33.7129840546697, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI4507047, Length=439, Percent_Identity=34.3963553530752, Blast_Score=218, Evalue=8e-57,
Organism=Homo sapiens, GI258645169, Length=439, Percent_Identity=34.1685649202733, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI114326544, Length=430, Percent_Identity=33.7209302325581, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI114326550, Length=430, Percent_Identity=33.7209302325581, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI186910308, Length=429, Percent_Identity=26.5734265734266, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI186910306, Length=429, Percent_Identity=26.5734265734266, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI186910304, Length=429, Percent_Identity=26.5734265734266, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI187423910, Length=493, Percent_Identity=25.7606490872211, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI7657591, Length=493, Percent_Identity=25.7606490872211, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI33286428, Length=432, Percent_Identity=25.462962962963, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI7657683, Length=406, Percent_Identity=24.6305418719212, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI71979932, Length=433, Percent_Identity=25.8660508083141, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI87081869, Length=442, Percent_Identity=23.9819004524887, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788480, Length=491, Percent_Identity=23.6252545824847, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87082023, Length=459, Percent_Identity=24.6187363834423, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081708, Length=466, Percent_Identity=22.3175965665236, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786694, Length=338, Percent_Identity=23.9644970414201, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082250, Length=415, Percent_Identity=25.3012048192771, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786302, Length=434, Percent_Identity=20.0460829493088, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789017, Length=438, Percent_Identity=22.8310502283105, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081915, Length=445, Percent_Identity=20.6741573033708, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790653, Length=454, Percent_Identity=21.8061674008811, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786789, Length=434, Percent_Identity=21.1981566820277, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=419, Percent_Identity=34.8448687350835, Blast_Score=251, Evalue=6e-67,
Organism=Caenorhabditis elegans, GI17531343, Length=429, Percent_Identity=32.4009324009324, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17533459, Length=435, Percent_Identity=32.4137931034483, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17540018, Length=413, Percent_Identity=25.181598062954, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17568033, Length=431, Percent_Identity=24.8259860788863, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI32566699, Length=382, Percent_Identity=23.8219895287958, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=366, Percent_Identity=23.224043715847, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=401, Percent_Identity=23.4413965087282, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71982612, Length=401, Percent_Identity=23.4413965087282, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322892, Length=371, Percent_Identity=23.989218328841, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321053, Length=491, Percent_Identity=20.5702647657841, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24667468, Length=424, Percent_Identity=37.2641509433962, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24666159, Length=423, Percent_Identity=35.4609929078014, Blast_Score=258, Evalue=8e-69,
Organism=Drosophila melanogaster, GI221512776, Length=423, Percent_Identity=35.4609929078014, Blast_Score=258, Evalue=8e-69,
Organism=Drosophila melanogaster, GI24668806, Length=423, Percent_Identity=33.806146572104, Blast_Score=241, Evalue=9e-64,
Organism=Drosophila melanogaster, GI21356285, Length=423, Percent_Identity=33.806146572104, Blast_Score=241, Evalue=9e-64,
Organism=Drosophila melanogaster, GI24668802, Length=423, Percent_Identity=33.806146572104, Blast_Score=241, Evalue=9e-64,
Organism=Drosophila melanogaster, GI161077963, Length=427, Percent_Identity=35.3629976580796, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI281366235, Length=412, Percent_Identity=33.9805825242718, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI116007820, Length=412, Percent_Identity=33.9805825242718, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=32.9297820823245, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=32.9297820823245, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21357367, Length=432, Percent_Identity=26.8518518518519, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221331183, Length=429, Percent_Identity=25.6410256410256, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI17647653, Length=429, Percent_Identity=25.6410256410256, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24664379, Length=429, Percent_Identity=25.6410256410256, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24651635, Length=430, Percent_Identity=23.7209302325581, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24651633, Length=430, Percent_Identity=23.7209302325581, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI45550968, Length=438, Percent_Identity=24.6575342465753, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921172, Length=438, Percent_Identity=24.6575342465753, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641993, Length=432, Percent_Identity=24.3055555555556, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641995, Length=432, Percent_Identity=24.3055555555556, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51189; Mature: 51189

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]