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The map label for this gene is mdh [H]

Identifier: 28379550

GI number: 28379550

Start: 2815899

End: 2816987

Strand: Direct

Name: mdh [H]

Synonym: lp_3150

Alternate gene names: 28379550

Gene position: 2815899-2816987 (Clockwise)

Preceding gene: 28379549

Following gene: 28379551

Centisome position: 85.12

GC content: 47.47

Gene sequence:

>1089_bases
ATGGTAAAACGATACAATAGCAAAAAAATTGAACAACTGATTTACAATATTTACAAAGGTTACGGCTTTACCGAAGAAGA
AAGCCAAGAAGTCGCCCACATGTTGATCTACACCGATTTGATTGGCATTGAATCCCATGGCGTCCAGCGAATGATCATGT
ATGACGACTTCATTCGTAACGGTAAGATTCGCGTACATAATCGGCCAGAAGTTGTTAAAGAAACCGATGTTAGTGCGGTC
GTTGACGCGCACTTTGGCTTGGGTCAATTGAACGGTATCTATAGCATGCGCCTAGCCATTGAAAAAGCAAAACAACACGG
TATCGGTATCGTTACGACTCGTAACTCCGGTCACTATGGTATTGCAGGTTACTATGCCAACATGGCTGCCGAAGAAGGTC
TGATTGGCCTGTCGTCGTGCAATTCACGTTCAGCGATGTTACCCACTCATGCTACCAAAGCATTGGTCGGCACCAACCCA
ATTGCCTTTGCCATGCCAGCCAACCCGAACACATTTATCTTCGACGCGGCCACAACGACGGTGCCACAAGGTAAAATTGA
AGTTTATCGTAAATTAGGTAAAGATATGCCCGCATTATGGGTCGCTAAGGATGGCGAAACGCCCGTTAATAGCCATAACG
ATACCAAAGACTTGGATGCCCTCCGTGATTTAGATTCCAATGTTGGTTTAGCTCCATTAGGTGGCGTTACCGAAGACACC
GGTAGCCACAAAGGGTTCGGTCTCGGTGTCATCGTCGAGGTTTTCACAGCAATCCTTTCAATGGGCAACACCTCCAACGA
AATTACTCCGGACGACCTTTCCGTGGGCCCTTGTCAGAGCTTTGTCGCCATCGACCCTTCAATCTTTGGTGATAAGGATG
CCATTATTGCTAAGTTTTCAGCTTACTTGCAAGCCATTCGCGACCTACCATCCGTTTCCGGCAAACCAGTCATCGTTGCC
GGCGATAAGGAAGCTGCCGCGTATCAAGACCGGTCAGCTAACGGCATCGAGATTGATGACAAGACACTCGCAGAAGTTAC
CGGAATCGCCAAGCGACTAGGGATCGACTACGCGCAATATGTTGATTAA

Upstream 100 bases:

>100_bases
GATTATTAAAATTCAATTGACATTCAAAGTCCTTATTATTATCATATTATAATATACAGGGCTGTCACTTAAGTCTATTT
CAAATAACGTGGTGAATGTA

Downstream 100 bases:

>100_bases
CTAATTTTGTTATTCATCTAATTTAAAAACCAGCAAGTCCGCGTTGAGCAACCTCTAATAACCGTTGTTTTTATCGCCAT
CGCCACAAAACATTGGTACT

Product: malate dehydrogenase (putative)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MVKRYNSKKIEQLIYNIYKGYGFTEEESQEVAHMLIYTDLIGIESHGVQRMIMYDDFIRNGKIRVHNRPEVVKETDVSAV
VDAHFGLGQLNGIYSMRLAIEKAKQHGIGIVTTRNSGHYGIAGYYANMAAEEGLIGLSSCNSRSAMLPTHATKALVGTNP
IAFAMPANPNTFIFDAATTTVPQGKIEVYRKLGKDMPALWVAKDGETPVNSHNDTKDLDALRDLDSNVGLAPLGGVTEDT
GSHKGFGLGVIVEVFTAILSMGNTSNEITPDDLSVGPCQSFVAIDPSIFGDKDAIIAKFSAYLQAIRDLPSVSGKPVIVA
GDKEAAAYQDRSANGIEIDDKTLAEVTGIAKRLGIDYAQYVD

Sequences:

>Translated_362_residues
MVKRYNSKKIEQLIYNIYKGYGFTEEESQEVAHMLIYTDLIGIESHGVQRMIMYDDFIRNGKIRVHNRPEVVKETDVSAV
VDAHFGLGQLNGIYSMRLAIEKAKQHGIGIVTTRNSGHYGIAGYYANMAAEEGLIGLSSCNSRSAMLPTHATKALVGTNP
IAFAMPANPNTFIFDAATTTVPQGKIEVYRKLGKDMPALWVAKDGETPVNSHNDTKDLDALRDLDSNVGLAPLGGVTEDT
GSHKGFGLGVIVEVFTAILSMGNTSNEITPDDLSVGPCQSFVAIDPSIFGDKDAIIAKFSAYLQAIRDLPSVSGKPVIVA
GDKEAAAYQDRSANGIEIDDKTLAEVTGIAKRLGIDYAQYVD
>Mature_362_residues
MVKRYNSKKIEQLIYNIYKGYGFTEEESQEVAHMLIYTDLIGIESHGVQRMIMYDDFIRNGKIRVHNRPEVVKETDVSAV
VDAHFGLGQLNGIYSMRLAIEKAKQHGIGIVTTRNSGHYGIAGYYANMAAEEGLIGLSSCNSRSAMLPTHATKALVGTNP
IAFAMPANPNTFIFDAATTTVPQGKIEVYRKLGKDMPALWVAKDGETPVNSHNDTKDLDALRDLDSNVGLAPLGGVTEDT
GSHKGFGLGVIVEVFTAILSMGNTSNEITPDDLSVGPCQSFVAIDPSIFGDKDAIIAKFSAYLQAIRDLPSVSGKPVIVA
GDKEAAAYQDRSANGIEIDDKTLAEVTGIAKRLGIDYAQYVD

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=359, Percent_Identity=26.1838440111421, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1786727, Length=348, Percent_Identity=28.735632183908, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1790000, Length=332, Percent_Identity=28.0120481927711, Blast_Score=118, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17507179, Length=358, Percent_Identity=33.7988826815642, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17536633, Length=323, Percent_Identity=32.5077399380805, Blast_Score=150, Evalue=7e-37,
Organism=Drosophila melanogaster, GI45553211, Length=360, Percent_Identity=34.1666666666667, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24667912, Length=360, Percent_Identity=34.1666666666667, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24667904, Length=360, Percent_Identity=34.1666666666667, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24667908, Length=360, Percent_Identity=34.1666666666667, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24648360, Length=327, Percent_Identity=28.4403669724771, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24658010, Length=311, Percent_Identity=26.6881028938907, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: =1.1.1.37 [H]

Molecular weight: Translated: 39139; Mature: 39139

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKRYNSKKIEQLIYNIYKGYGFTEEESQEVAHMLIYTDLIGIESHGVQRMIMYDDFIRN
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCC
GKIRVHNRPEVVKETDVSAVVDAHFGLGQLNGIYSMRLAIEKAKQHGIGIVTTRNSGHYG
CEEEECCCCCHHHHCCHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCE
IAGYYANMAAEEGLIGLSSCNSRSAMLPTHATKALVGTNPIAFAMPANPNTFIFDAATTT
EHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCEEEEECCCCC
VPQGKIEVYRKLGKDMPALWVAKDGETPVNSHNDTKDLDALRDLDSNVGLAPLGGVTEDT
CCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
GSHKGFGLGVIVEVFTAILSMGNTSNEITPDDLSVGPCQSFVAIDPSIFGDKDAIIAKFS
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHH
AYLQAIRDLPSVSGKPVIVAGDKEAAAYQDRSANGIEIDDKTLAEVTGIAKRLGIDYAQY
HHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCCCCEECCHHHHHHHHHHHHHCCCHHHH
VD
CC
>Mature Secondary Structure
MVKRYNSKKIEQLIYNIYKGYGFTEEESQEVAHMLIYTDLIGIESHGVQRMIMYDDFIRN
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCC
GKIRVHNRPEVVKETDVSAVVDAHFGLGQLNGIYSMRLAIEKAKQHGIGIVTTRNSGHYG
CEEEECCCCCHHHHCCHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCE
IAGYYANMAAEEGLIGLSSCNSRSAMLPTHATKALVGTNPIAFAMPANPNTFIFDAATTT
EHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCEEEEECCCCC
VPQGKIEVYRKLGKDMPALWVAKDGETPVNSHNDTKDLDALRDLDSNVGLAPLGGVTEDT
CCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
GSHKGFGLGVIVEVFTAILSMGNTSNEITPDDLSVGPCQSFVAIDPSIFGDKDAIIAKFS
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHH
AYLQAIRDLPSVSGKPVIVAGDKEAAAYQDRSANGIEIDDKTLAEVTGIAKRLGIDYAQY
HHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCCCCEECCHHHHHHHHHHHHHCCCHHHH
VD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]