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The map label for this gene is dfrA [H]

Identifier: 28379511

GI number: 28379511

Start: 2758531

End: 2759568

Strand: Direct

Name: dfrA [H]

Synonym: lp_3098

Alternate gene names: 28379511

Gene position: 2758531-2759568 (Clockwise)

Preceding gene: 28379509

Following gene: 28379515

Centisome position: 83.38

GC content: 49.61

Gene sequence:

>1038_bases
ATGCAAAAACAATTAGTCGTCGTCACTGGTGGTAGCGGTTTTATCGCCATTCATATCATTCGTCAATTATTACAACAAGG
CTACGCCGTCCGCACAACGGTCCGCTCATTAGCCAAAGCACCCGTTATTAAAGAAATGCTGACCAATGGTGGTATCACCG
ACTTATCAGCTCTCGAAATTGTTGTGGCCGACCTGGCGCATGATGAACACTGGTCGGAAGCGATGGCCGGAGCCACTTAT
GCGATCGACGTCGCTTCCCCAACCCCAAAGCTCAACTTCAAAAACAAAGCTGAAATGATCCGACCAGCCGTTGACGGTGT
TCGGCGGGTTCTAACTGCTAGTCGTGATGCGGGCGTTAAACGAGTCGTGTTAACGTCTGCGTACGGGGCCATCTTTGCTG
GTCACAAAAATCGTACGACCCCCTACACTGAAGCTGACTGGTCTGATCTCAACTGGAAAGCGATCCATCCTTATCAAGAA
TCCAAGACACGTGCTGAATTAGCAGCTTGGGACTTTATTAACCATGAGGGCCGCGGGTTAGAATTAACAACGGTCAATCC
CGTTGCCGTCATGGGTCCGGTGTTGTCCGCCAAATATTCACATTCCAATATTCAAATCCAACAATTCTTAGAAGGCCAAG
TTAAAGCCGTTCCAAACGTTGATTCCGGTTATGTTGATGTTCGTGACGTGGCTAGTCTGCACTTGCTTGCCATGACCGCA
CCGCAAGCTAACGGCGAACGTTTTCTAGCCACAACGGGTGAGACGCTATCCATGCTTGACGTTGCAAATGTCTTAAGACA
GGCCTTTCCAGCTTTTGCCAGTCAGCTACCAACCAAAACCATTCCCAATGCAGCGGTTAAGCTAGCCGCTAAGGCCCGAC
CAGAATTGCGAATGGTCGCCTCACTAGTTGGCACCTACGCGGAAACGAGCAATCATAAAGCCCAAACATTGTTGGATTGG
CATCCCCGTCCCGCTGCGGAATCGATTATTGCAACCGCCCAATCTATGATTGACCTAGGAATCGTCACCAAACCATAA

Upstream 100 bases:

>100_bases
GCTCGTGATTACCTTGTATTCGTCGTGACCCCATTGTAAGATACTGGCACAGACGTTACAAGTGTAACAGCAATTCATAA
ATTCATTTGGAGGTAGTCCC

Downstream 100 bases:

>100_bases
GCATACTCCTACTAACACCAACTAAATACTAACCGGCAACGCCCGCAAGATTGGACTCAGTATTCAACCTTGCGGGCGTT
GTCGTTCGTTATCATTGCGA

Product: oxidoreductase (putative)

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MQKQLVVVTGGSGFIAIHIIRQLLQQGYAVRTTVRSLAKAPVIKEMLTNGGITDLSALEIVVADLAHDEHWSEAMAGATY
AIDVASPTPKLNFKNKAEMIRPAVDGVRRVLTASRDAGVKRVVLTSAYGAIFAGHKNRTTPYTEADWSDLNWKAIHPYQE
SKTRAELAAWDFINHEGRGLELTTVNPVAVMGPVLSAKYSHSNIQIQQFLEGQVKAVPNVDSGYVDVRDVASLHLLAMTA
PQANGERFLATTGETLSMLDVANVLRQAFPAFASQLPTKTIPNAAVKLAAKARPELRMVASLVGTYAETSNHKAQTLLDW
HPRPAAESIIATAQSMIDLGIVTKP

Sequences:

>Translated_345_residues
MQKQLVVVTGGSGFIAIHIIRQLLQQGYAVRTTVRSLAKAPVIKEMLTNGGITDLSALEIVVADLAHDEHWSEAMAGATY
AIDVASPTPKLNFKNKAEMIRPAVDGVRRVLTASRDAGVKRVVLTSAYGAIFAGHKNRTTPYTEADWSDLNWKAIHPYQE
SKTRAELAAWDFINHEGRGLELTTVNPVAVMGPVLSAKYSHSNIQIQQFLEGQVKAVPNVDSGYVDVRDVASLHLLAMTA
PQANGERFLATTGETLSMLDVANVLRQAFPAFASQLPTKTIPNAAVKLAAKARPELRMVASLVGTYAETSNHKAQTLLDW
HPRPAAESIIATAQSMIDLGIVTKP
>Mature_345_residues
MQKQLVVVTGGSGFIAIHIIRQLLQQGYAVRTTVRSLAKAPVIKEMLTNGGITDLSALEIVVADLAHDEHWSEAMAGATY
AIDVASPTPKLNFKNKAEMIRPAVDGVRRVLTASRDAGVKRVVLTSAYGAIFAGHKNRTTPYTEADWSDLNWKAIHPYQE
SKTRAELAAWDFINHEGRGLELTTVNPVAVMGPVLSAKYSHSNIQIQQFLEGQVKAVPNVDSGYVDVRDVASLHLLAMTA
PQANGERFLATTGETLSMLDVANVLRQAFPAFASQLPTKTIPNAAVKLAAKARPELRMVASLVGTYAETSNHKAQTLLDW
HPRPAAESIIATAQSMIDLGIVTKP

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71987463, Length=345, Percent_Identity=36.5217391304348, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324421, Length=356, Percent_Identity=28.6516853932584, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320750, Length=295, Percent_Identity=31.864406779661, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321399, Length=357, Percent_Identity=25.2100840336134, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6321281, Length=362, Percent_Identity=25.414364640884, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 37321; Mature: 37321

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKQLVVVTGGSGFIAIHIIRQLLQQGYAVRTTVRSLAKAPVIKEMLTNGGITDLSALEI
CCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHH
VVADLAHDEHWSEAMAGATYAIDVASPTPKLNFKNKAEMIRPAVDGVRRVLTASRDAGVK
HHHHHHCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
RVVLTSAYGAIFAGHKNRTTPYTEADWSDLNWKAIHPYQESKTRAELAAWDFINHEGRGL
EEEEEHHHHHEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCE
ELTTVNPVAVMGPVLSAKYSHSNIQIQQFLEGQVKAVPNVDSGYVDVRDVASLHLLAMTA
EEEECCCHHHHHHHHHCCCCCCCCHHHHHHCCHHEECCCCCCCCEEHHHHHHEEEEEEEC
PQANGERFLATTGETLSMLDVANVLRQAFPAFASQLPTKTIPNAAVKLAAKARPELRMVA
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHH
SLVGTYAETSNHKAQTLLDWHPRPAAESIIATAQSMIDLGIVTKP
HHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQKQLVVVTGGSGFIAIHIIRQLLQQGYAVRTTVRSLAKAPVIKEMLTNGGITDLSALEI
CCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHH
VVADLAHDEHWSEAMAGATYAIDVASPTPKLNFKNKAEMIRPAVDGVRRVLTASRDAGVK
HHHHHHCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
RVVLTSAYGAIFAGHKNRTTPYTEADWSDLNWKAIHPYQESKTRAELAAWDFINHEGRGL
EEEEEHHHHHEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCE
ELTTVNPVAVMGPVLSAKYSHSNIQIQQFLEGQVKAVPNVDSGYVDVRDVASLHLLAMTA
EEEECCCHHHHHHHHHCCCCCCCCHHHHHHCCHHEECCCCCCCCEEHHHHHHEEEEEEEC
PQANGERFLATTGETLSMLDVANVLRQAFPAFASQLPTKTIPNAAVKLAAKARPELRMVA
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHH
SLVGTYAETSNHKAQTLLDWHPRPAAESIIATAQSMIDLGIVTKP
HHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]