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The map label for this gene is yugS [H]

Identifier: 28379179

GI number: 28379179

Start: 2372628

End: 2373995

Strand: Direct

Name: yugS [H]

Synonym: lp_2671

Alternate gene names: 28379179

Gene position: 2372628-2373995 (Clockwise)

Preceding gene: 28379176

Following gene: 28379180

Centisome position: 71.72

GC content: 42.18

Gene sequence:

>1368_bases
TTGGACAGTGGCCAGATAATTTTAAATTTAGTCATTATTGTCATTACGTTCTTCGTCGCGGCTTTCTTTGTGGCCTGTGA
ATTTGCACTCGTTCAGACCCGCCCTAGCGCTCTCGAAGAAGAACAAAAAAAACGTGATAAACCGTCAAAACGGATCGCAA
CTTCTTTGCACATGGTCCGCAACCTTAACGAGTATCTTTCAACCACCCAAGTGGGGGTCTCGTTAGCTGGTATCATTTTA
GGTTGGATTGGTGAACAAACAACTGAACACTTTGTGCTTGATTTCTTATCCCTCTTCAACCTATCCGTCTCAACCGCGGT
ATTACGAGGTATTAGTATCGTCATTGGGGTTTTCCTACTGACCTACTTAGAAGTGGTCTTAACCGAAATCGTGCCTAAAA
ATATCGCAATCGACATGCCACTCAAAGTAATGGCAGTCATTACGACACCATTACGGTGGTTCCACGTGATGTTCTACCCC
TTTGTATGGTTGTTGAATGTCTCATCAGCTGGCGTCGTCAAAATGTTAGGCATCCCAGTTGCGAATGAAGATAATGATGT
TTATTCACAAGCCGAAATTCTTAACCTATCACGAAATGCCGTAACTGGCGGTGAGCTTGAACGTAACGATTACCTTTACA
TGGAGCGGGCATTTGAGTTCAATGACAAGATCGCTAAGGATATCATGATCGACCGTACTCAGCTAGTTGTGATTGATATC
AACGATACCGTCAAGCAAGCCATTCGCGTTTATTTACAGAAACGCTTTAGCCGCTTACCCGTCGTAGCTAACAATGATAA
GGACAAGATTCTGGGTTACGTTTATAACTATGACTTAATTCGCCAAGGTGAAGTTGACGATGATATTCGGGTCAATAAGT
TATTGCGTAATATCATTACAATTCCTGAAACTACACCGATTCAAGCTATTCTCCAAAAGATGATCGACAAACAAACGCCG
ATCGTCGTCGTGGTTGATGAATATGGTGGGACCAGTGGGATCGTCACTGATAAGGATATTTACGAAGAACTTTTCGGAAC
CGTCAATGACGAAATCGACAATGTTTCTAACGAATACATCGAAAAGCAGGCCGATGGCACTTACCGCATCAGTGGTAAGA
TGACCATCTACGACTTTGAACGCTACTTCAAGACCGACTTACAAGAATTTGAAGATTCCGATGTTGTCACTTTGACCGGT
TATATTTTGGATAATTTTCCTAAAATCCAAGCCGGTGATACGATTCAAATCGGTAACTTCAATTTCAAAGCGCTTGATTT
TGAAAATGCTTATATCAATTGGTTTGAGGTTAGCGCCCAGAGGGATAGCACACCTGACGATCATAATGACGATCAAACAC
AAGACTAA

Upstream 100 bases:

>100_bases
ACCGTCGCGGGGGCTGACAAAACGGGTGATAAGCCTTATAATATTAGCTACTTCGCGTTATACTTAAAGTAACTAATATT
ATGAAATGAGGAATGTTTCT

Downstream 100 bases:

>100_bases
ATATTTACACGCACTACTTAAAATGGCACTTAAGAAAGTTGATTTCTTAGGGGCCATTTTTTTGTATCCGGCGAACTTCA
ACTGGTCAACTTTGGTACTT

Product: integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MDSGQIILNLVIIVITFFVAAFFVACEFALVQTRPSALEEEQKKRDKPSKRIATSLHMVRNLNEYLSTTQVGVSLAGIIL
GWIGEQTTEHFVLDFLSLFNLSVSTAVLRGISIVIGVFLLTYLEVVLTEIVPKNIAIDMPLKVMAVITTPLRWFHVMFYP
FVWLLNVSSAGVVKMLGIPVANEDNDVYSQAEILNLSRNAVTGGELERNDYLYMERAFEFNDKIAKDIMIDRTQLVVIDI
NDTVKQAIRVYLQKRFSRLPVVANNDKDKILGYVYNYDLIRQGEVDDDIRVNKLLRNIITIPETTPIQAILQKMIDKQTP
IVVVVDEYGGTSGIVTDKDIYEELFGTVNDEIDNVSNEYIEKQADGTYRISGKMTIYDFERYFKTDLQEFEDSDVVTLTG
YILDNFPKIQAGDTIQIGNFNFKALDFENAYINWFEVSAQRDSTPDDHNDDQTQD

Sequences:

>Translated_455_residues
MDSGQIILNLVIIVITFFVAAFFVACEFALVQTRPSALEEEQKKRDKPSKRIATSLHMVRNLNEYLSTTQVGVSLAGIIL
GWIGEQTTEHFVLDFLSLFNLSVSTAVLRGISIVIGVFLLTYLEVVLTEIVPKNIAIDMPLKVMAVITTPLRWFHVMFYP
FVWLLNVSSAGVVKMLGIPVANEDNDVYSQAEILNLSRNAVTGGELERNDYLYMERAFEFNDKIAKDIMIDRTQLVVIDI
NDTVKQAIRVYLQKRFSRLPVVANNDKDKILGYVYNYDLIRQGEVDDDIRVNKLLRNIITIPETTPIQAILQKMIDKQTP
IVVVVDEYGGTSGIVTDKDIYEELFGTVNDEIDNVSNEYIEKQADGTYRISGKMTIYDFERYFKTDLQEFEDSDVVTLTG
YILDNFPKIQAGDTIQIGNFNFKALDFENAYINWFEVSAQRDSTPDDHNDDQTQD
>Mature_455_residues
MDSGQIILNLVIIVITFFVAAFFVACEFALVQTRPSALEEEQKKRDKPSKRIATSLHMVRNLNEYLSTTQVGVSLAGIIL
GWIGEQTTEHFVLDFLSLFNLSVSTAVLRGISIVIGVFLLTYLEVVLTEIVPKNIAIDMPLKVMAVITTPLRWFHVMFYP
FVWLLNVSSAGVVKMLGIPVANEDNDVYSQAEILNLSRNAVTGGELERNDYLYMERAFEFNDKIAKDIMIDRTQLVVIDI
NDTVKQAIRVYLQKRFSRLPVVANNDKDKILGYVYNYDLIRQGEVDDDIRVNKLLRNIITIPETTPIQAILQKMIDKQTP
IVVVVDEYGGTSGIVTDKDIYEELFGTVNDEIDNVSNEYIEKQADGTYRISGKMTIYDFERYFKTDLQEFEDSDVVTLTG
YILDNFPKIQAGDTIQIGNFNFKALDFENAYINWFEVSAQRDSTPDDHNDDQTQD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=394, Percent_Identity=33.756345177665, Blast_Score=226, Evalue=3e-59,
Organism=Escherichia coli, GI1790664, Length=444, Percent_Identity=23.1981981981982, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI145693175, Length=436, Percent_Identity=25, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87082033, Length=230, Percent_Identity=26.5217391304348, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786879, Length=234, Percent_Identity=29.0598290598291, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 51781; Mature: 51781

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSGQIILNLVIIVITFFVAAFFVACEFALVQTRPSALEEEQKKRDKPSKRIATSLHMVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHH
NLNEYLSTTQVGVSLAGIILGWIGEQTTEHFVLDFLSLFNLSVSTAVLRGISIVIGVFLL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TYLEVVLTEIVPKNIAIDMPLKVMAVITTPLRWFHVMFYPFVWLLNVSSAGVVKMLGIPV
HHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHEECCCC
ANEDNDVYSQAEILNLSRNAVTGGELERNDYLYMERAFEFNDKIAKDIMIDRTQLVVIDI
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEEC
NDTVKQAIRVYLQKRFSRLPVVANNDKDKILGYVYNYDLIRQGEVDDDIRVNKLLRNIIT
CHHHHHHHHHHHHHHHHCCCEEECCCCHHEEEEEECCCEEECCCCCCHHHHHHHHHHHHC
IPETTPIQAILQKMIDKQTPIVVVVDEYGGTSGIVTDKDIYEELFGTVNDEIDNVSNEYI
CCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EKQADGTYRISGKMTIYDFERYFKTDLQEFEDSDVVTLTGYILDNFPKIQAGDTIQIGNF
HHCCCCCEEEECEEEEEHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCEEEECCE
NFKALDFENAYINWFEVSAQRDSTPDDHNDDQTQD
EEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDSGQIILNLVIIVITFFVAAFFVACEFALVQTRPSALEEEQKKRDKPSKRIATSLHMVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHH
NLNEYLSTTQVGVSLAGIILGWIGEQTTEHFVLDFLSLFNLSVSTAVLRGISIVIGVFLL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TYLEVVLTEIVPKNIAIDMPLKVMAVITTPLRWFHVMFYPFVWLLNVSSAGVVKMLGIPV
HHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHEECCCC
ANEDNDVYSQAEILNLSRNAVTGGELERNDYLYMERAFEFNDKIAKDIMIDRTQLVVIDI
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEEC
NDTVKQAIRVYLQKRFSRLPVVANNDKDKILGYVYNYDLIRQGEVDDDIRVNKLLRNIIT
CHHHHHHHHHHHHHHHHCCCEEECCCCHHEEEEEECCCEEECCCCCCHHHHHHHHHHHHC
IPETTPIQAILQKMIDKQTPIVVVVDEYGGTSGIVTDKDIYEELFGTVNDEIDNVSNEYI
CCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EKQADGTYRISGKMTIYDFERYFKTDLQEFEDSDVVTLTGYILDNFPKIQAGDTIQIGNF
HHCCCCCEEEECEEEEEHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCEEEECCE
NFKALDFENAYINWFEVSAQRDSTPDDHNDDQTQD
EEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]