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The map label for this gene is trpG [H]

Identifier: 28378345

GI number: 28378345

Start: 1508203

End: 1508778

Strand: Direct

Name: trpG [H]

Synonym: lp_1653

Alternate gene names: 28378345

Gene position: 1508203-1508778 (Clockwise)

Preceding gene: 28378344

Following gene: 28378346

Centisome position: 45.59

GC content: 47.74

Gene sequence:

>576_bases
ATGGAATTATTAATTGATAACTATGACAGCTTTACTTATAACTTGTATCAACTAATTGGTCGTCTGACGCCCGATGTACG
GGTCATTAAAAATGACGATTTGACGGTTGCTGCAATCAAGGCATTACAACCTGACCATATCATTTTATCACCAGGGCCGG
GGACGCCAGCCCACACGGGAGTTAGTCCACAAGTCGTGCAACAATTAGCTGGTCAGGTCCCCATATTGGGGATTTGTATG
GGATTAGAAGTGATGGTCACCGCTTTTGGCGGTTCGCTGCAAGGCGCCCAGCATTTAGTTCACGGGCAAGCCACGTTAAT
GCACGTGCAGCCGTCATCACTATTTAAAGATTGTCCGATGCAGTTCATGGCAGCGCGCTACCACTCGTTGGTAGCTGATG
CGGGCCGTTTGCCCGTTAACTTTCGAATCATTGGGACAAGCGATGATCAGGAAATCATGGCAGTGGAAGATGTGGGCCGT
CAGCTGTACGGCGTTCAATTTCATCCAGAATCAATCATGACGCCAGCCGCCGTTGGTGAGCAACTGATCCGTAATTTTTT
AGCACTTAAACATTAA

Upstream 100 bases:

>100_bases
ATTGTTGCTGACAGTATCGGCGCTCAAGAATTTAAGGAGTGCCAGAATAAACAACGAGTGATCGTTAATGCAGTACAAGA
CGCGAAAGGACGAGTTAAAG

Downstream 100 bases:

>100_bases
GCAGACGAGAGTGGAGGAATACTTATGATTGAAACAGCGATTGCACAACTCACTAACCAAGAAAATCTAGACTTTACAAT
GAGCCAACAAGTCATTACGG

Product: anthranilate synthase, component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MELLIDNYDSFTYNLYQLIGRLTPDVRVIKNDDLTVAAIKALQPDHIILSPGPGTPAHTGVSPQVVQQLAGQVPILGICM
GLEVMVTAFGGSLQGAQHLVHGQATLMHVQPSSLFKDCPMQFMAARYHSLVADAGRLPVNFRIIGTSDDQEIMAVEDVGR
QLYGVQFHPESIMTPAAVGEQLIRNFLALKH

Sequences:

>Translated_191_residues
MELLIDNYDSFTYNLYQLIGRLTPDVRVIKNDDLTVAAIKALQPDHIILSPGPGTPAHTGVSPQVVQQLAGQVPILGICM
GLEVMVTAFGGSLQGAQHLVHGQATLMHVQPSSLFKDCPMQFMAARYHSLVADAGRLPVNFRIIGTSDDQEIMAVEDVGR
QLYGVQFHPESIMTPAAVGEQLIRNFLALKH
>Mature_191_residues
MELLIDNYDSFTYNLYQLIGRLTPDVRVIKNDDLTVAAIKALQPDHIILSPGPGTPAHTGVSPQVVQQLAGQVPILGICM
GLEVMVTAFGGSLQGAQHLVHGQATLMHVQPSSLFKDCPMQFMAARYHSLVADAGRLPVNFRIIGTSDDQEIMAVEDVGR
QLYGVQFHPESIMTPAAVGEQLIRNFLALKH

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=44.9197860962567, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1787517, Length=189, Percent_Identity=33.8624338624339, Blast_Score=105, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322638, Length=186, Percent_Identity=39.247311827957, Blast_Score=149, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=30.3317535545024, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 20798; Mature: 20798

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLIDNYDSFTYNLYQLIGRLTPDVRVIKNDDLTVAAIKALQPDHIILSPGPGTPAHTG
CCEEECCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEHHHCCCCEEEEECCCCCCCCCC
VSPQVVQQLAGQVPILGICMGLEVMVTAFGGSLQGAQHLVHGQATLMHVQPSSLFKDCPM
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECHHHHHHHCCH
QFMAARYHSLVADAGRLPVNFRIIGTSDDQEIMAVEDVGRQLYGVQFHPESIMTPAAVGE
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCEEECCHHHCCHHHHHH
QLIRNFLALKH
HHHHHHHHCCC
>Mature Secondary Structure
MELLIDNYDSFTYNLYQLIGRLTPDVRVIKNDDLTVAAIKALQPDHIILSPGPGTPAHTG
CCEEECCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEHHHCCCCEEEEECCCCCCCCCC
VSPQVVQQLAGQVPILGICMGLEVMVTAFGGSLQGAQHLVHGQATLMHVQPSSLFKDCPM
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECHHHHHHHCCH
QFMAARYHSLVADAGRLPVNFRIIGTSDDQEIMAVEDVGRQLYGVQFHPESIMTPAAVGE
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCEEECCHHHCCHHHHHH
QLIRNFLALKH
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673; 2403545; 11677609 [H]