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The map label for this gene is sunL [H]

Identifier: 28378317

GI number: 28378317

Start: 1471215

End: 1472558

Strand: Direct

Name: sunL [H]

Synonym: lp_1617

Alternate gene names: 28378317

Gene position: 1471215-1472558 (Clockwise)

Preceding gene: 28378316

Following gene: 28378318

Centisome position: 44.47

GC content: 46.5

Gene sequence:

>1344_bases
ATGAGTACAGTTGGTAATACCCCCCGCTGGTTAGCGGTCGCCGCCTTAGCGAAGATTAAGAACGGTGCATATTCAAATTT
GCAATTAAACCAGTTAATCAATGATCATCAGATGGATCGGCGTGACATTAATCTGCTGACAAATATGGTTTACGGTGTCA
TTCAACATCGGTTGACTCTCGAATACTGGTTGACCCCGTTTGTTCGACATCCGCACCAGATTGACCCCTGGGTACGGGAG
CTCTTATTGAGCGCATTGTATCAATGGCAGTATCTGGATAAGATTCCACAACGGGCCGTTTTCAACGAAACGATTGAAAT
TGCTAAGGTCAAAGGTCACCCTGGCATTCGGCGGTTTGTAACCGGCGTCTTACATCAAATGGATCGCTCAGGACTACCGA
GTTTTGATGCGATTAAAAATCCTGATGAACGGTTGAGTGTGACTTATAGCATGCCAATATGGTTGATTCAAGAATTGCGG
CGTCAATTAGGTGCTGAAAAGATGGAGCGAATCTTATCATCATTGAACCAACCAGCTAAGCAAGCCTTACGTGTCAACCC
GGCCTTGTCGACGGTTGAAGATGTGACAACGGCGCTGATTAATGATGGTTTGACAATTACGCCGAGTGAAATCTCACCGT
TAGGGCTGATTGCAACGGATGGTCAGGCCATTAATACTGAAGCGATGCGGTATGGCATGTTCACAGTTCAAGATGAAAGT
GCACAATTAGTTGTGCCAGCACTCAATCCGCAGCCGAATGATCGAGTCTTGGATGCTTGTGCGGCCCCCGGGGGCAAGAC
GACCCAGATTGCGGCTAGTTTAGATGCTGAGCAGGGTGGCACAGTCGTTGCCCTTGATATTCATGCCAATAAAGTGAAAC
TGATCGGTCAAAATGCGGCGCGCATGCACGTTGCTGATCGCGTTGAGGCCACCGAACTCGATGCCCGTAAAGTTGAGACG
CAGTTTAATGCTGAAAGTTTTGATCGAATTTTAGTCGATGCTCCGTGTTCGGGACTGGGATTGATGCGCCGGAAGCCTGA
GATTCGCTATGAGAAACAGTTGCAGGATAGTTTGAACTTGCAACGAATTCAGCTGGCAATTTTGACAGCGGTCGCCCCAA
CCTTGAAAAAAGGTGGTATCATGACGTATAGTACGTGCACGATTTTGCAACAGGAAAATCAGGATGTGATTACCAAATTC
TTAGCGGATCACCCAGATTTTGAGCTGCAAACAACGCCAACTGAACGAGACTTGAAAACTGATCGAACGGAAAAGACTTT
GTCGATTTATCCCGATGATTATTTATCCGACGGCTTTTTCATTGCTTGTTTGCGAAAAAAATAA

Upstream 100 bases:

>100_bases
TCAATCAGTTGCAGCCAGCTGGTAAACCGAAGATGACAATTACAGACTATTTAAATGGGGCGGCAGATAAGTTCGCTACC
GGAGAGCAGGTTATTAATAA

Downstream 100 bases:

>100_bases
TGGTGGAGTGGTAAACAATGGATTTTGCATACCGGTCGGATATTGGCCAACAACGTGAAGAAAATGAGGACTATGTCGGC
TTTTTTCAAAATAAAGCGGG

Product: rRNA methylase (putative)

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSTVGNTPRWLAVAALAKIKNGAYSNLQLNQLINDHQMDRRDINLLTNMVYGVIQHRLTLEYWLTPFVRHPHQIDPWVRE
LLLSALYQWQYLDKIPQRAVFNETIEIAKVKGHPGIRRFVTGVLHQMDRSGLPSFDAIKNPDERLSVTYSMPIWLIQELR
RQLGAEKMERILSSLNQPAKQALRVNPALSTVEDVTTALINDGLTITPSEISPLGLIATDGQAINTEAMRYGMFTVQDES
AQLVVPALNPQPNDRVLDACAAPGGKTTQIAASLDAEQGGTVVALDIHANKVKLIGQNAARMHVADRVEATELDARKVET
QFNAESFDRILVDAPCSGLGLMRRKPEIRYEKQLQDSLNLQRIQLAILTAVAPTLKKGGIMTYSTCTILQQENQDVITKF
LADHPDFELQTTPTERDLKTDRTEKTLSIYPDDYLSDGFFIACLRKK

Sequences:

>Translated_447_residues
MSTVGNTPRWLAVAALAKIKNGAYSNLQLNQLINDHQMDRRDINLLTNMVYGVIQHRLTLEYWLTPFVRHPHQIDPWVRE
LLLSALYQWQYLDKIPQRAVFNETIEIAKVKGHPGIRRFVTGVLHQMDRSGLPSFDAIKNPDERLSVTYSMPIWLIQELR
RQLGAEKMERILSSLNQPAKQALRVNPALSTVEDVTTALINDGLTITPSEISPLGLIATDGQAINTEAMRYGMFTVQDES
AQLVVPALNPQPNDRVLDACAAPGGKTTQIAASLDAEQGGTVVALDIHANKVKLIGQNAARMHVADRVEATELDARKVET
QFNAESFDRILVDAPCSGLGLMRRKPEIRYEKQLQDSLNLQRIQLAILTAVAPTLKKGGIMTYSTCTILQQENQDVITKF
LADHPDFELQTTPTERDLKTDRTEKTLSIYPDDYLSDGFFIACLRKK
>Mature_446_residues
STVGNTPRWLAVAALAKIKNGAYSNLQLNQLINDHQMDRRDINLLTNMVYGVIQHRLTLEYWLTPFVRHPHQIDPWVREL
LLSALYQWQYLDKIPQRAVFNETIEIAKVKGHPGIRRFVTGVLHQMDRSGLPSFDAIKNPDERLSVTYSMPIWLIQELRR
QLGAEKMERILSSLNQPAKQALRVNPALSTVEDVTTALINDGLTITPSEISPLGLIATDGQAINTEAMRYGMFTVQDESA
QLVVPALNPQPNDRVLDACAAPGGKTTQIAASLDAEQGGTVVALDIHANKVKLIGQNAARMHVADRVEATELDARKVETQ
FNAESFDRILVDAPCSGLGLMRRKPEIRYEKQLQDSLNLQRIQLAILTAVAPTLKKGGIMTYSTCTILQQENQDVITKFL
ADHPDFELQTTPTERDLKTDRTEKTLSIYPDDYLSDGFFIACLRKK

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=321, Percent_Identity=29.595015576324, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI76150623, Length=321, Percent_Identity=29.595015576324, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI32698918, Length=185, Percent_Identity=40, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI39995082, Length=178, Percent_Identity=34.2696629213483, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI301336155, Length=178, Percent_Identity=34.2696629213483, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI8922322, Length=235, Percent_Identity=31.4893617021277, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI270288816, Length=235, Percent_Identity=31.4893617021277, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI270288818, Length=235, Percent_Identity=31.4893617021277, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI23199998, Length=235, Percent_Identity=31.4893617021277, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI11545785, Length=175, Percent_Identity=30.8571428571429, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI40316918, Length=189, Percent_Identity=29.1005291005291, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367212, Length=422, Percent_Identity=31.5165876777251, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87081985, Length=312, Percent_Identity=30.7692307692308, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17536757, Length=302, Percent_Identity=32.1192052980132, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI115534021, Length=224, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71998419, Length=224, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25143471, Length=173, Percent_Identity=33.5260115606936, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324268, Length=281, Percent_Identity=30.2491103202847, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319447, Length=176, Percent_Identity=33.5227272727273, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324306, Length=208, Percent_Identity=25, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI22024126, Length=343, Percent_Identity=30.6122448979592, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24668781, Length=199, Percent_Identity=34.6733668341709, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356513, Length=199, Percent_Identity=34.6733668341709, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355201, Length=179, Percent_Identity=32.9608938547486, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356579, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920494, Length=159, Percent_Identity=30.188679245283, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50118; Mature: 49987

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVGNTPRWLAVAALAKIKNGAYSNLQLNQLINDHQMDRRDINLLTNMVYGVIQHRLTL
CCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHH
EYWLTPFVRHPHQIDPWVRELLLSALYQWQYLDKIPQRAVFNETIEIAKVKGHPGIRRFV
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHH
TGVLHQMDRSGLPSFDAIKNPDERLSVTYSMPIWLIQELRRQLGAEKMERILSSLNQPAK
HHHHHHHHHCCCCCCHHCCCCCHHEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHCHHHH
QALRVNPALSTVEDVTTALINDGLTITPSEISPLGLIATDGQAINTEAMRYGMFTVQDES
HHHCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCCCCHHHHHCCEEEEECCC
AQLVVPALNPQPNDRVLDACAAPGGKTTQIAASLDAEQGGTVVALDIHANKVKLIGQNAA
CEEEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEEEECCCCH
RMHVADRVEATELDARKVETQFNAESFDRILVDAPCSGLGLMRRKPEIRYEKQLQDSLNL
HHHHHHHCHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCHHHHCCCCCHHHHHHHHCCCH
QRIQLAILTAVAPTLKKGGIMTYSTCTILQQENQDVITKFLADHPDFELQTTPTERDLKT
HHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCCC
DRTEKTLSIYPDDYLSDGFFIACLRKK
CCCCCEEEECCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
STVGNTPRWLAVAALAKIKNGAYSNLQLNQLINDHQMDRRDINLLTNMVYGVIQHRLTL
CCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHH
EYWLTPFVRHPHQIDPWVRELLLSALYQWQYLDKIPQRAVFNETIEIAKVKGHPGIRRFV
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHH
TGVLHQMDRSGLPSFDAIKNPDERLSVTYSMPIWLIQELRRQLGAEKMERILSSLNQPAK
HHHHHHHHHCCCCCCHHCCCCCHHEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHCHHHH
QALRVNPALSTVEDVTTALINDGLTITPSEISPLGLIATDGQAINTEAMRYGMFTVQDES
HHHCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCCCCHHHHHCCEEEEECCC
AQLVVPALNPQPNDRVLDACAAPGGKTTQIAASLDAEQGGTVVALDIHANKVKLIGQNAA
CEEEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEEEECCCCH
RMHVADRVEATELDARKVETQFNAESFDRILVDAPCSGLGLMRRKPEIRYEKQLQDSLNL
HHHHHHHCHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCHHHHCCCCCHHHHHHHHCCCH
QRIQLAILTAVAPTLKKGGIMTYSTCTILQQENQDVITKFLADHPDFELQTTPTERDLKT
HHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCCC
DRTEKTLSIYPDDYLSDGFFIACLRKK
CCCCCEEEECCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]