Click here to switch to the map view.

The map label for this gene is opuB [H]

Identifier: 28378308

GI number: 28378308

Start: 1462618

End: 1463247

Strand: Direct

Name: opuB [H]

Synonym: lp_1608

Alternate gene names: 28378308

Gene position: 1462618-1463247 (Clockwise)

Preceding gene: 28378307

Following gene: 28378309

Centisome position: 44.21

GC content: 46.83

Gene sequence:

>630_bases
ATGATAACTTTCCTACAAAACTACGGCATGCAGCTGCTGGTTAAGACGTGGCAACACTTGTATATTTCGGCGTTTTCATT
GTTCTTAGGCATTATCGTAGCGGTTCCGATTGGAATTCTGCTTACGCGGGTGAAGCCGATTGCGAATGTGGTCATGTCAA
TCGCTAGTATGTTGCAAACGATCCCAGCGATGGCGTTGTTGGCATTGATGATCCCGTTTTTCGGGATTGGTGCAATTCCA
GCTATCATTGCGCTGTTCATCTATTCTTTATTACCGATTCTCCGCAATACCTATCTTGGACTGGAAGACGTTGATCCGGC
CTTGATCGATGCGGCTAAGGGAATGGGAATGACCGGTTGGCAGTCAATTGTTAAAGTTGAGTTACCGATGGCAGCCCCAG
TTATTATGGCTGGTATTCGATTATCCGCAACGTACGTTATTGCCTGGGCCGCGTTAGCATCATACATTGGTGCCGGTGGC
CTTGGGGACTTTATCTTTAATGGGTTAAACCTCTATCGAACTGACTTGATTTTAGGCGGTTCGATTCCAGTGATTATCTT
AGCCCTCATCGTTGATTGGCTGTTGGGTAAACTAGAAGCAGCGGTTACCCCAAGAACCACACAAGCGTAG

Upstream 100 bases:

>100_bases
TTGTTTATGATGCTCTCTGGGGTGATGAAGACGAAGATGAAGCTGAAAATAATATTCATCATGGGGAGGACGATGCGCCC
GCTGAAGGCGGTGAACAGGC

Downstream 100 bases:

>100_bases
GGGGGATTAAAGATGAAGAAAATTAAAAAGTGGTTGTTAGGTGTTTTCGCAACGGTCGCCAGTGCGTTATTATTGGCCGG
CTGTGGCTTTCCGGGTTTGT

Product: glycine betaine/carnitine/choline ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MITFLQNYGMQLLVKTWQHLYISAFSLFLGIIVAVPIGILLTRVKPIANVVMSIASMLQTIPAMALLALMIPFFGIGAIP
AIIALFIYSLLPILRNTYLGLEDVDPALIDAAKGMGMTGWQSIVKVELPMAAPVIMAGIRLSATYVIAWAALASYIGAGG
LGDFIFNGLNLYRTDLILGGSIPVIILALIVDWLLGKLEAAVTPRTTQA

Sequences:

>Translated_209_residues
MITFLQNYGMQLLVKTWQHLYISAFSLFLGIIVAVPIGILLTRVKPIANVVMSIASMLQTIPAMALLALMIPFFGIGAIP
AIIALFIYSLLPILRNTYLGLEDVDPALIDAAKGMGMTGWQSIVKVELPMAAPVIMAGIRLSATYVIAWAALASYIGAGG
LGDFIFNGLNLYRTDLILGGSIPVIILALIVDWLLGKLEAAVTPRTTQA
>Mature_209_residues
MITFLQNYGMQLLVKTWQHLYISAFSLFLGIIVAVPIGILLTRVKPIANVVMSIASMLQTIPAMALLALMIPFFGIGAIP
AIIALFIYSLLPILRNTYLGLEDVDPALIDAAKGMGMTGWQSIVKVELPMAAPVIMAGIRLSATYVIAWAALASYIGAGG
LGDFIFNGLNLYRTDLILGGSIPVIILALIVDWLLGKLEAAVTPRTTQA

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=190, Percent_Identity=39.4736842105263, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1788451, Length=191, Percent_Identity=34.0314136125654, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789033, Length=164, Percent_Identity=34.7560975609756, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87081802, Length=189, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786564, Length=195, Percent_Identity=28.2051282051282, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22388; Mature: 22388

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFLQNYGMQLLVKTWQHLYISAFSLFLGIIVAVPIGILLTRVKPIANVVMSIASMLQT
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPAMALLALMIPFFGIGAIPAIIALFIYSLLPILRNTYLGLEDVDPALIDAAKGMGMTGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHH
QSIVKVELPMAAPVIMAGIRLSATYVIAWAALASYIGAGGLGDFIFNGLNLYRTDLILGG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCC
SIPVIILALIVDWLLGKLEAAVTPRTTQA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MITFLQNYGMQLLVKTWQHLYISAFSLFLGIIVAVPIGILLTRVKPIANVVMSIASMLQT
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPAMALLALMIPFFGIGAIPAIIALFIYSLLPILRNTYLGLEDVDPALIDAAKGMGMTGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHH
QSIVKVELPMAAPVIMAGIRLSATYVIAWAALASYIGAGGLGDFIFNGLNLYRTDLILGG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCC
SIPVIILALIVDWLLGKLEAAVTPRTTQA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]