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The map label for this gene is coaE [H]

Identifier: 28378224

GI number: 28378224

Start: 1381986

End: 1382588

Strand: Direct

Name: coaE [H]

Synonym: lp_1510

Alternate gene names: 28378224

Gene position: 1381986-1382588 (Clockwise)

Preceding gene: 28378223

Following gene: 28378225

Centisome position: 41.77

GC content: 49.09

Gene sequence:

>603_bases
GTGATCAAGATGACAAAGTTGATTGGATTGACTGGTGGCATTGCCACTGGTAAGTCGACTGTTTCTAAGCTGCTGGCAAC
TAAGTTACCAATCGTTGATGCGGATAAAATCGCGTGGCAGGTTGAAGGGCCAGGCCAACCGACGACCCAAAAAATTGTGG
CGCACTTTGGTCAGCAAGCAGTGCTGGCAGACGGGCGGCTGAATCGGCCATGGCTTGGCCAGTTGGTTTTTAACGATGCT
CAAGCTTTACAAGCCTTAACCGCAATTACACGGTTACCGATTCAGTACGCGATGTTCGAAGCGATTGTCGCGGCGAACCA
GCAACAGCCAGACGCAATTATTTTAGATGTGCCGTTGTTATTTGAAAGTGGCTGGCAACACGTTTGTGATCAAGTGTTGG
TTGTGACGGCATCACCCGCCGTAGTATTGCAGCGGTTGATGGCGCGTAACCACTTATCGCAACAGGCGGCTCAGGCACGA
ATTGACAGCCAAATGCCACTTGCACAGAAGGTCGCAAGGGCTGACGTTGTCATTGATAACGGGGCCAACATTGATAAAAC
TAAAGCAGCCGTGTTAAAATGGCTGAAAACTATTACTAAATAA

Upstream 100 bases:

>100_bases
TCGTGAAGGGGAGCCTTGCGAACGGTGTGGCACAATTATTGAGAAAATCAAAGTGGCACAGCGAGGGACCCATTTTTGCC
CGTTAGAACAACGGTTGTAG

Downstream 100 bases:

>100_bases
AGAAAAACTGATTGTTAGTTGTTACAAGGGGTGAGAAGTCTATGCAATGTCCACATTGTCATCATAATGGCTCCCGCGTG
GTTGACAGTCGACCAACTGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MIKMTKLIGLTGGIATGKSTVSKLLATKLPIVDADKIAWQVEGPGQPTTQKIVAHFGQQAVLADGRLNRPWLGQLVFNDA
QALQALTAITRLPIQYAMFEAIVAANQQQPDAIILDVPLLFESGWQHVCDQVLVVTASPAVVLQRLMARNHLSQQAAQAR
IDSQMPLAQKVARADVVIDNGANIDKTKAAVLKWLKTITK

Sequences:

>Translated_200_residues
MIKMTKLIGLTGGIATGKSTVSKLLATKLPIVDADKIAWQVEGPGQPTTQKIVAHFGQQAVLADGRLNRPWLGQLVFNDA
QALQALTAITRLPIQYAMFEAIVAANQQQPDAIILDVPLLFESGWQHVCDQVLVVTASPAVVLQRLMARNHLSQQAAQAR
IDSQMPLAQKVARADVVIDNGANIDKTKAAVLKWLKTITK
>Mature_200_residues
MIKMTKLIGLTGGIATGKSTVSKLLATKLPIVDADKIAWQVEGPGQPTTQKIVAHFGQQAVLADGRLNRPWLGQLVFNDA
QALQALTAITRLPIQYAMFEAIVAANQQQPDAIILDVPLLFESGWQHVCDQVLVVTASPAVVLQRLMARNHLSQQAAQAR
IDSQMPLAQKVARADVVIDNGANIDKTKAAVLKWLKTITK

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=188, Percent_Identity=37.7659574468085, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI191252795, Length=188, Percent_Identity=37.7659574468085, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI110227607, Length=173, Percent_Identity=31.7919075144509, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI110227605, Length=175, Percent_Identity=31.4285714285714, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI110227603, Length=175, Percent_Identity=31.4285714285714, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI110227601, Length=175, Percent_Identity=31.4285714285714, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI205277394, Length=175, Percent_Identity=31.4285714285714, Blast_Score=85, Evalue=4e-17,
Organism=Escherichia coli, GI1786292, Length=191, Percent_Identity=33.5078534031414, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17554944, Length=188, Percent_Identity=37.2340425531915, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI25143409, Length=196, Percent_Identity=25.5102040816327, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=184, Percent_Identity=44.5652173913043, Blast_Score=148, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24644728, Length=188, Percent_Identity=37.2340425531915, Blast_Score=136, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24658602, Length=198, Percent_Identity=36.8686868686869, Blast_Score=117, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21646; Mature: 21646

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKMTKLIGLTGGIATGKSTVSKLLATKLPIVDADKIAWQVEGPGQPTTQKIVAHFGQQA
CCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCE
VLADGRLNRPWLGQLVFNDAQALQALTAITRLPIQYAMFEAIVAANQQQPDAIILDVPLL
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHH
FESGWQHVCDQVLVVTASPAVVLQRLMARNHLSQQAAQARIDSQMPLAQKVARADVVIDN
HHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEEC
GANIDKTKAAVLKWLKTITK
CCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKMTKLIGLTGGIATGKSTVSKLLATKLPIVDADKIAWQVEGPGQPTTQKIVAHFGQQA
CCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCE
VLADGRLNRPWLGQLVFNDAQALQALTAITRLPIQYAMFEAIVAANQQQPDAIILDVPLL
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHH
FESGWQHVCDQVLVVTASPAVVLQRLMARNHLSQQAAQARIDSQMPLAQKVARADVVIDN
HHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEEC
GANIDKTKAAVLKWLKTITK
CCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]